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The map label for this gene is nuoA1 [H]

Identifier: 108563629

GI number: 108563629

Start: 1266396

End: 1266797

Strand: Direct

Name: nuoA1 [H]

Synonym: HPAG1_1204

Alternate gene names: 108563629

Gene position: 1266396-1266797 (Clockwise)

Preceding gene: 108563628

Following gene: 108563630

Centisome position: 79.33

GC content: 39.05

Gene sequence:

>402_bases
ATGCAACAAGCCACAGAAGCATTGAATCACCCCTATTTTGGCGTTTTTGTTTTGCTAGTATTCACCTTTTGGGTGTTTAA
CTTAACCTTAAGGATTCAAAGGTTTTTAAGCCGTAAAATGGCTCAAAAAAAGGGCGAAAAGCTCAAGCTCGCTCCCTATG
AATGCGGGCCTGTGGCTCTCAAGCAGCCTAATAGGGTGTCGCACCATTTCTATATCATGGCCATGCTTTTTATTTTATTT
GATGTAGAAATCGTTTTCATGTTCCCTTGGGCGATTGATTTTAAAAAGTTAGGCTTGTTTGGGCTCATTGAAATGCTAGG
CTTTGTCTTCTTTTTAATGATTGGTTTTATTTACGCTTTAAAGCGAAACGCTTTGAGCTGGCAGAAATTAGAGGTGAAAT
AA

Upstream 100 bases:

>100_bases
TGAAATAATTTTTATTTTTTCAGCTAACGATTAGCAAAAACATGGTTTAATTGGCTTCATCGTTTGCTGAAAGTAATAAT
TAAAGGAGTCTGAGAGCCTA

Downstream 100 bases:

>100_bases
TGCAACAAGCACCGGTTGTTCTAAGCACTTTGGATAAATTATTGAATTGGGGGCGTTCTAATTCGCTCTGGCCCTTAACT
TATGGCTTGGCGTGTTGCGC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1 [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MQQATEALNHPYFGVFVLLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVALKQPNRVSHHFYIMAMLFILF
DVEIVFMFPWAIDFKKLGLFGLIEMLGFVFFLMIGFIYALKRNALSWQKLEVK

Sequences:

>Translated_133_residues
MQQATEALNHPYFGVFVLLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVALKQPNRVSHHFYIMAMLFILF
DVEIVFMFPWAIDFKKLGLFGLIEMLGFVFFLMIGFIYALKRNALSWQKLEVK
>Mature_133_residues
MQQATEALNHPYFGVFVLLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVALKQPNRVSHHFYIMAMLFILF
DVEIVFMFPWAIDFKKLGLFGLIEMLGFVFFLMIGFIYALKRNALSWQKLEVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=130, Percent_Identity=30, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15721; Mature: 15721

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQATEALNHPYFGVFVLLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVAL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
KQPNRVSHHFYIMAMLFILFDVEIVFMFPWAIDFKKLGLFGLIEMLGFVFFLMIGFIYAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNALSWQKLEVK
HHCCCCCHHCCCC
>Mature Secondary Structure
MQQATEALNHPYFGVFVLLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVAL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
KQPNRVSHHFYIMAMLFILFDVEIVFMFPWAIDFKKLGLFGLIEMLGFVFFLMIGFIYAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNALSWQKLEVK
HHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA