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The map label for this gene is dorA [H]

Identifier: 108563410

GI number: 108563410

Start: 1036156

End: 1038546

Strand: Reverse

Name: dorA [H]

Synonym: HPAG1_0985

Alternate gene names: 108563410

Gene position: 1038546-1036156 (Counterclockwise)

Preceding gene: 108563411

Following gene: 108563409

Centisome position: 65.06

GC content: 41.49

Gene sequence:

>2391_bases
ATGTCCATTTCACGCAGAAGTATCCTAACAAAAGTCCCAATCGCACTCGCTAGCACTAATGTTTTGAAAGCTACTGGTGT
TTTTGAAAAAGTAGAATCCATTCCGCATGCAACGCATTTTGGCCCCTTTATCGCAAAGGTTCAAAACGGAGTGATTAAAG
ATATTATCCCCCAAAAGAGCGATTATAACCCTACCATGATGTTAAAAGCGATGGTTGATAGGGTGTATTCAGATAGTAGG
GTGAAGTATCCTTGCGTGCGTAAGAGTTTCTTAGAAAACAAAAAAAACCACAAAGAATTGCGCGGGAGAGAAGAGTTTGT
GCGTGTGAGTTGGGATGTGGCGTTGGATTTGGCGGCTAAAAAACTTAAAGAAATCCCTAAAGAAAACATTTATAATGCCA
GTTATGGTGGTTGGGGGCATGCGGGCAGCTTGCATCGTTGCCATCATTTAACATGGCGTTTTTTTAATACGACTTTAGGG
GGGGCTATTGGCACTGATGGGGAATATAGTAATGGCGCGGCTGCAAGAATAAACCCTATGATTGTAGGGGATATGGAAGT
TTATTCGCAACAAACCACGCATGAAGAGATGATTAAAAATTGTAAGGTGTATGTCATGTGGGGGGCGGATTTACTCAAGT
GCAACCGCATTGATTATTTTGTGCCAAACCATGTCAATGACAGCTACTACCCCAAGTATAAAAGAGCCGGTATTAAATTC
ATTAGTATCGATCCCATTTATACCGAAACCGCTCAAGCCTTTAACGCTGAATGGATACCCATTCGCCCTAATACTGATGT
AGCGTTGATGCTAGGCATGATGCATTATCTTTATACGAGCAATCAATATGATAAAGCGTTTATCGCTAAATACACTGATG
GTTTTGATAAATTTTTACCCTATTTGCTAGGAGAGAGCGATAATGCACCTAAGACTTTAGAATGGGCGTCTCAAATCACT
GGAGTGAGTGCAGAAAAAATCAAAGAATTAGCGGATTTATTTGTCTCTAAACGCACTTTTTTAGCGGGTAATTGGGCCAT
GCAAAGAGCTCAGTATGGCGAGCAACCGGATTGGGCGTTAATTGTTTTAGCTAGCATGATTGGTCAAGTGGGCTTATCTG
GTGGGGGCTTTGGCTTTTCTATGCATTATGGAGGGAACGCTCAAGCAAGCTCAGGGGCAAGAATTGTTCCGATGATTTCA
CAAGGGCATAATTCTGTAAAAAGCGTTATTCCAGCATCTAGAATTTCTGAAGCGATTTTAAACCCGGATAAAGAAATTGA
TTTTATGGGCAAAAAACTCAAATTGCCTAAAATCAAAATGATTTATAATTGTGGGGCGGATTTGTTAGGGCATGAAGCTG
ATACAAACGAGCTGATTCGCGCTTTAAGGACCTTAGATTGCGTGATCGTGCATGAGCCTTGGTGGACGCCTACGGCAAAA
TTTGCTGATATTGTCTTTGCTTCCACTAGCACTATGGAAAGAGATGATATTACTTTTGGAGGGAGTTATTCTAAGAATGT
GGTTTATGCCATGCGTAAGGTGGTAGAGCCTGTTTATGAATCTAAAGACGATTATGAGATTTTCAGACAGCTTGCTTTAC
GCATTGGGGGCAATGAAACAGAACAGAAATTCACTGAATCTAAGAGTTACATGGAATGGATTAAGAGCCTTTATGAAAAA
AGCGATGGCCCTACTTTGAAATCGTTTGATCAATTTTGGAGGGATGGCTTTGTGGAGTTTGAAATCCCTGAAAATGCGAG
AAAGTTTGTGCGTCATGCGAAATTCAGGCAAGACCCTATTAATAATAAGCTGGATACAGAGAGCGGGAAAATTCAAATTT
TTTCTCAAAAATGTGCGGATTTTAAACTAGCTGATTTTAAAGGGTATCCTACTTGGTTTGAGCCAGCTGAGTGGCTAGGC
TCTAAAATGGCTGAGACTTATCCGTTCCATTTGATCTCTCCGCACCCAAAATACCGTGTCAATTCACAGCTTGATAACAC
TTGGGTTAGGAATGTGTATAAAATTCAAGGCAGAGAGCCTGTAATGATCAACGAACTAGACGCTAATAAATTAGGCATTA
GGCATGGTGAAATTGTAGAAGTGTTTAACGCTAGGGGGAGGTTGTTAGCAGGGGCGTTTGTAACTAAGAATATCCGTCAA
GGGGTTTTGAGTATCCAAAAAGGGGCGTGGTATGACCCAGAAGATGCGAGGGTTAGAAACCCACGATGCAATGCGGGGCA
TGTGAATACGCTCACTTCTTTGCGCCCCACAAGCAGCATGACACAAGCCATTTCAGCCAATACCGCCTTAGTTAATATCA
GAAGACTCAGAAGGTATGAATTAGTCAAGCCCTATCATTCCATTTCAACACCAAGCATTATTGGGGCTTAA

Upstream 100 bases:

>100_bases
TAAATTAACGTCCATGCTGAGGGCTTATTAGCGGTAATTTTAGGTGAATCTATGTTAGAATTTGGGGTGTTTTAACAGAA
TGCAAGCTTGAAGGAGAACC

Downstream 100 bases:

>100_bases
AAGGAGTGAAAATACTAGCATGAGGGTGTTTTAGAAAGACTTAAGTGCTAAAGACTTGAGCGCTAGCCAAGCTAAAGCGT
AATTCTCAATTTTTATATTA

Product: biotin sulfoxide reductase

Products: NA

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MSISRRSILTKVPIALASTNVLKATGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKSDYNPTMMLKAMVDRVYSDSR
VKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAKKLKEIPKENIYNASYGGWGHAGSLHRCHHLTWRFFNTTLG
GAIGTDGEYSNGAAARINPMIVGDMEVYSQQTTHEEMIKNCKVYVMWGADLLKCNRIDYFVPNHVNDSYYPKYKRAGIKF
ISIDPIYTETAQAFNAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLPYLLGESDNAPKTLEWASQIT
GVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWALIVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMIS
QGHNSVKSVIPASRISEAILNPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVVEPVYESKDDYEIFRQLALRIGGNETEQKFTESKSYMEWIKSLYEK
SDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPINNKLDTESGKIQIFSQKCADFKLADFKGYPTWFEPAEWLG
SKMAETYPFHLISPHPKYRVNSQLDNTWVRNVYKIQGREPVMINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
GVLSIQKGAWYDPEDARVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRRLRRYELVKPYHSISTPSIIGA

Sequences:

>Translated_796_residues
MSISRRSILTKVPIALASTNVLKATGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKSDYNPTMMLKAMVDRVYSDSR
VKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAKKLKEIPKENIYNASYGGWGHAGSLHRCHHLTWRFFNTTLG
GAIGTDGEYSNGAAARINPMIVGDMEVYSQQTTHEEMIKNCKVYVMWGADLLKCNRIDYFVPNHVNDSYYPKYKRAGIKF
ISIDPIYTETAQAFNAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLPYLLGESDNAPKTLEWASQIT
GVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWALIVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMIS
QGHNSVKSVIPASRISEAILNPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVVEPVYESKDDYEIFRQLALRIGGNETEQKFTESKSYMEWIKSLYEK
SDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPINNKLDTESGKIQIFSQKCADFKLADFKGYPTWFEPAEWLG
SKMAETYPFHLISPHPKYRVNSQLDNTWVRNVYKIQGREPVMINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
GVLSIQKGAWYDPEDARVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRRLRRYELVKPYHSISTPSIIGA
>Mature_795_residues
SISRRSILTKVPIALASTNVLKATGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKSDYNPTMMLKAMVDRVYSDSRV
KYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAKKLKEIPKENIYNASYGGWGHAGSLHRCHHLTWRFFNTTLGG
AIGTDGEYSNGAAARINPMIVGDMEVYSQQTTHEEMIKNCKVYVMWGADLLKCNRIDYFVPNHVNDSYYPKYKRAGIKFI
SIDPIYTETAQAFNAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLPYLLGESDNAPKTLEWASQITG
VSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWALIVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMISQ
GHNSVKSVIPASRISEAILNPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAKF
ADIVFASTSTMERDDITFGGSYSKNVVYAMRKVVEPVYESKDDYEIFRQLALRIGGNETEQKFTESKSYMEWIKSLYEKS
DGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPINNKLDTESGKIQIFSQKCADFKLADFKGYPTWFEPAEWLGS
KMAETYPFHLISPHPKYRVNSQLDNTWVRNVYKIQGREPVMINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQG
VLSIQKGAWYDPEDARVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRRLRRYELVKPYHSISTPSIIGA

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=803, Percent_Identity=37.4844333748443, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI145693196, Length=770, Percent_Identity=38.5714285714286, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI1787231, Length=774, Percent_Identity=39.6640826873385, Blast_Score=526, Evalue=1e-150,
Organism=Escherichia coli, GI87081797, Length=757, Percent_Identity=31.8361955085865, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1787870, Length=756, Percent_Identity=30.952380952381, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI171474008, Length=760, Percent_Identity=29.0789473684211, Blast_Score=250, Evalue=3e-67,
Organism=Escherichia coli, GI3868721, Length=646, Percent_Identity=23.374613003096, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 90193; Mature: 90062

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISRRSILTKVPIALASTNVLKATGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKS
CCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCC
DYNPTMMLKAMVDRVYSDSRVKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAK
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHEEEHHHHHHHHHHH
KLKEIPKENIYNASYGGWGHAGSLHRCHHLTWRFFNTTLGGAIGTDGEYSNGAAARINPM
HHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCE
IVGDMEVYSQQTTHEEMIKNCKVYVMWGADLLKCNRIDYFVPNHVNDSYYPKYKRAGIKF
EEECHHHHHHHCHHHHHHHCCEEEEEECCCEEEECCCCEECCCCCCCCCCCCHHHCCEEE
ISIDPIYTETAQAFNAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLP
EEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
YLLGESDNAPKTLEWASQITGVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWAL
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCHHH
IVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMISQGHNSVKSVIPASRISEAIL
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEHHCCCHHHHHHCCHHHHHHHHC
NPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
CCCCCHHHCCCCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHCEEEEECCCCCCCHH
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVVEPVYESKDDYEIFRQLALRIGGNET
HHHEEEECCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EQKFTESKSYMEWIKSLYEKSDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCC
NNKLDTESGKIQIFSQKCADFKLADFKGYPTWFEPAEWLGSKMAETYPFHLISPHPKYRV
CCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCC
NSQLDNTWVRNVYKIQGREPVMINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
CCCHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHH
GVLSIQKGAWYDPEDARVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRRLRRYE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHH
LVKPYHSISTPSIIGA
HHCCHHCCCCCCCCCC
>Mature Secondary Structure 
SISRRSILTKVPIALASTNVLKATGVFEKVESIPHATHFGPFIAKVQNGVIKDIIPQKS
CCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCC
DYNPTMMLKAMVDRVYSDSRVKYPCVRKSFLENKKNHKELRGREEFVRVSWDVALDLAAK
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCHHHHEEEHHHHHHHHHHH
KLKEIPKENIYNASYGGWGHAGSLHRCHHLTWRFFNTTLGGAIGTDGEYSNGAAARINPM
HHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCE
IVGDMEVYSQQTTHEEMIKNCKVYVMWGADLLKCNRIDYFVPNHVNDSYYPKYKRAGIKF
EEECHHHHHHHCHHHHHHHCCEEEEEECCCEEEECCCCEECCCCCCCCCCCCHHHCCEEE
ISIDPIYTETAQAFNAEWIPIRPNTDVALMLGMMHYLYTSNQYDKAFIAKYTDGFDKFLP
EEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
YLLGESDNAPKTLEWASQITGVSAEKIKELADLFVSKRTFLAGNWAMQRAQYGEQPDWAL
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECHHHHHHHHCCCCCCHHH
IVLASMIGQVGLSGGGFGFSMHYGGNAQASSGARIVPMISQGHNSVKSVIPASRISEAIL
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEHHCCCHHHHHHCCHHHHHHHHC
NPDKEIDFMGKKLKLPKIKMIYNCGADLLGHEADTNELIRALRTLDCVIVHEPWWTPTAK
CCCCCHHHCCCCCCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHCEEEEECCCCCCCHH
FADIVFASTSTMERDDITFGGSYSKNVVYAMRKVVEPVYESKDDYEIFRQLALRIGGNET
HHHEEEECCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
EQKFTESKSYMEWIKSLYEKSDGPTLKSFDQFWRDGFVEFEIPENARKFVRHAKFRQDPI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCC
NNKLDTESGKIQIFSQKCADFKLADFKGYPTWFEPAEWLGSKMAETYPFHLISPHPKYRV
CCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCC
NSQLDNTWVRNVYKIQGREPVMINELDANKLGIRHGEIVEVFNARGRLLAGAFVTKNIRQ
CCCHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHH
GVLSIQKGAWYDPEDARVRNPRCNAGHVNTLTSLRPTSSMTQAISANTALVNIRRLRRYE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHH
LVKPYHSISTPSIIGA
HHCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8856102; 8890911; 8890912; 10835270; 10985771 [H]