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The map label for this gene is hypA

Identifier: 108563277

GI number: 108563277

Start: 885353

End: 885706

Strand: Reverse

Name: hypA

Synonym: HPAG1_0852

Alternate gene names: 108563277

Gene position: 885706-885353 (Counterclockwise)

Preceding gene: 108563278

Following gene: 108563276

Centisome position: 55.48

GC content: 39.55

Gene sequence:

>354_bases
ATGCATGAATACTCGGTCGTTTCTTCTTTAATCGCTCTTTGCGAAGAGCATGCGAAGAAAAATCAAGCCCATAAGATTGA
AAGAGTTGTGGTCGGTATTGGTGAAAGAAGCGCTATGGATAAGAGCTTGTTTGTGAGCGCGTTTGAGACTTTTAGAGAAG
AATCTTTGGTGTGTAAAGACGCTATTTTAGACATTGTAGATGAAAAGGTTGAATTAGAATGCAAGGATTGCTCGCATGTT
TTTAAGCCTAACGCGCTAGATTATGGGGTGTGTGAGAAATGCCACAGCAAGAATGTTATTATCACCCAAGGCAATGAAAT
GCGTTTGTTGTCTTTAGAAATGTTAGCGGAATAA

Upstream 100 bases:

>100_bases
TCTGATCAAATCCTTAATACCCTATTGAATCTTAAGCAATAAACCAAAGGATTACTCTAATACAATATAATAGGGGCTAA
TTTAAAGATTAAGGTTTAGT

Downstream 100 bases:

>100_bases
CCGATGCAAGAAGAATTGAACGCTTACCAGCAAGAAATTGAAGACACTAGGGAAGTTTTAAAAAAAATCCGTTTGGAATT
GAAGCAAGTCCAAGAAATCT

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHV
FKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE

Sequences:

>Translated_117_residues
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHV
FKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE
>Mature_117_residues
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKDAILDIVDEKVELECKDCSHV
FKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE

Specific function: Plays a role in both the hydrogenase and the urease nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_HELPJ (P0A0U5)

Other databases:

- EMBL:   AE001439
- PIR:   E64628
- RefSeq:   NP_223521.1
- STRING:   P0A0U5
- GeneID:   890093
- GenomeReviews:   AE001439_GR
- KEGG:   hpj:jhp0803
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   AFETFKL
- ProtClustDB:   PRK00564
- BioCyc:   HPYL85963:JHP0803-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 13202; Mature: 13202

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKD
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AILDIVDEKVELECKDCSHVFKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE
HHHHHHHHHHEEEHHHHHHHCCCCCCCHHHHHHHCCCCEEEECCCCEEEEHHHHHCC
>Mature Secondary Structure
MHEYSVVSSLIALCEEHAKKNQAHKIERVVVGIGERSAMDKSLFVSAFETFREESLVCKD
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AILDIVDEKVELECKDCSHVFKPNALDYGVCEKCHSKNVIITQGNEMRLLSLEMLAE
HHHHHHHHHHEEEHHHHHHHCCCCCCCHHHHHHHCCCCEEEECCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682