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The map label for this gene is gmhB [H]

Identifier: 108563268

GI number: 108563268

Start: 878595

End: 879116

Strand: Reverse

Name: gmhB [H]

Synonym: HPAG1_0843

Alternate gene names: 108563268

Gene position: 879116-878595 (Counterclockwise)

Preceding gene: 108563269

Following gene: 108563267

Centisome position: 55.07

GC content: 35.63

Gene sequence:

>522_bases
ATGAACACTAACAAAGCCCTTTTTTTGGACAGAGACGGCATTATCAATATTGACAAAGGTTATGTGAGTCAAAAAGAAGA
TTTTGAGTTTCAAAAAGGGATTTTTGAATTGCTAAAGCATGCGAAATCTTTAGGCTACAAACTGCTTTTAATCACCAACC
AATCCGGGATCAACCGAGGCTATTACACCCTTAAAGATTTTGAAAATCTCACCCAATATCTCCAAGAAAGCTTGCTTAAA
GAATTAGGTTTTAATTTGGATGGCATCTATTTTTGCAGGCACGCCCCAGAAGAAAATTGCGCTTGCAGAAAGCCAAAACC
CTTTTTGATTTTACAAGCCGCTAAAGAGCATCAAATTTGCTTGGAGCAATCTTTTATGATAGGCGATAAAGAGAGCGACA
TGTTAGCCGGCTTGAACGCTAAAGTTAAAAATAACCTTTTATTGAGCACAAATTTTTTAAAAACTCCTCATTCTTGGATA
CAATGTAAAGATCTTAAAGAGATGATGGAACTAATCAAATAA

Upstream 100 bases:

>100_bases
GTCTTTTATATGGGGATCATGCTCATTAATCATAAAATGCCTCATGCGATGCATCATCAAAACAGCACCACTCAGCATGA
TCATAAAGGAGTGCATTCGC

Downstream 100 bases:

>100_bases
GGATAAGAATGCGTTATATTGATGATGGATTAGAAAATCAAACGATTTTAATCACCGGTGGGGCTGGCTTTGTAGGCAGT
AATTTGGCCTTTTATTTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRGYYTLKDFENLTQYLQESLLK
ELGFNLDGIYFCRHAPEENCACRKPKPFLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLSTNFLKTPHSWI
QCKDLKEMMELIK

Sequences:

>Translated_173_residues
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRGYYTLKDFENLTQYLQESLLK
ELGFNLDGIYFCRHAPEENCACRKPKPFLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLSTNFLKTPHSWI
QCKDLKEMMELIK
>Mature_173_residues
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRGYYTLKDFENLTQYLQESLLK
ELGFNLDGIYFCRHAPEENCACRKPKPFLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLSTNFLKTPHSWI
QCKDLKEMMELIK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=160, Percent_Identity=41.25, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI87082027, Length=136, Percent_Identity=33.8235294117647, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20002; Mature: 20002

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRG
CCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCC
YYTLKDFENLTQYLQESLLKELGFNLDGIYFCRHAPEENCACRKPKPFLILQAAKEHQIC
CEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHH
LEQSFMIGDKESDMLAGLNAKVKNNLLLSTNFLKTPHSWIQCKDLKEMMELIK
HHHHHCCCCCCCHHHHCCCCHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRG
CCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCC
YYTLKDFENLTQYLQESLLKELGFNLDGIYFCRHAPEENCACRKPKPFLILQAAKEHQIC
CEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHH
LEQSFMIGDKESDMLAGLNAKVKNNLLLSTNFLKTPHSWIQCKDLKEMMELIK
HHHHHCCCCCCCHHHHCCCCHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 12101286 [H]