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The map label for this gene is moaC [H]

Identifier: 108563208

GI number: 108563208

Start: 822874

End: 823350

Strand: Reverse

Name: moaC [H]

Synonym: HPAG1_0783

Alternate gene names: 108563208

Gene position: 823350-822874 (Counterclockwise)

Preceding gene: 108563209

Following gene: 108563207

Centisome position: 51.58

GC content: 40.67

Gene sequence:

>477_bases
ATGCCACTCACTCATTTGAATGAAGAAAATCAGCCTAAAATGGTGGATATAGGGGATAAAGAAACCACTGAAAGAATCGC
TCTAGCAAGCGGTCGTATCAGCATGAATAAAGAGGCTTATGACGCTATTATCAATCATGGCGTTAAAAAGGGTCCGGTGT
TACAGACTGCTATTATTGCTGGGATCATGGGGGCTAAAAAGACAAGCGAGCTCATTCCCATGTGCCATCCAATCATGCTC
AATGGGGTGGATATTGATATTTTAGAAGAAAAAGAAACTCATAGTTTTAAACTCTATGCGAGAGTCAAAACTCAAGCTAA
AACAGGCGTGGAAATGGAAGCGCTAATGAGTGTGAGCATAGGGCTTTTAACCATTTATGACATGGTGAAAGCCATTGATA
AGAGCATGACAATTAGCGGTGTGATGCTAGAGCATAAAAGTGGAGGCAAAAGTGGGGATTATAACGCTAAAAAATAG

Upstream 100 bases:

>100_bases
TTCCAGCGATTCCTTATTGCGTGGATTTGATTTTAGGGAATTATATGCAAGTGAATGAAAAAAACATTCAAGCGTTTCGC
CCCAAACAATAAGGTAAAAA

Downstream 100 bases:

>100_bases
AAAAAGACTGATAATCTAAAGATGTTAGGGTAAAATAACATTTTGACAACAAAAGCGTGTTGGTTGGTTTGTTGTTATAG
AAGTCTAAAATATTACAATC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIML
NGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK

Sequences:

>Translated_158_residues
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIML
NGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
>Mature_157_residues
PLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIMLN
GVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=46.0526315789474, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.9530201342282, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=45.2702702702703, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=46.7153284671533, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17259; Mature: 17128

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIA
CCCCCCCCCCCCCEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
GIMGAKKTSELIPMCHPIMLNGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSI
HHHCCCCCHHHCCCCCCEEECCCCEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHH
GLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIA
CCCCCCCCCCCCEEECCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
GIMGAKKTSELIPMCHPIMLNGVDIDILEEKETHSFKLYARVKTQAKTGVEMEALMSVSI
HHHCCCCCHHHCCCCCCEEECCCCEEEECCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHH
GLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA