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The map label for this gene is hsdS [H]

Identifier: 108563200

GI number: 108563200

Start: 813528

End: 814862

Strand: Reverse

Name: hsdS [H]

Synonym: HPAG1_0775

Alternate gene names: 108563200

Gene position: 814862-813528 (Counterclockwise)

Preceding gene: 108563201

Following gene: 108563196

Centisome position: 51.04

GC content: 35.51

Gene sequence:

>1335_bases
ATGCATAAAATAGAGCGCTTACTCCAAACTCTAGCGCCTAAGGGGGTGGAGTTTAGGAAGTTGGGGGAGGTGCTAGAGTA
TGATCAACCCAATCAATATTGCGTAACGAGTAAAGAATTTGATAAAAGTTATCCTACCCCCGTTTTAACCGCAGGAAAAA
CCTTTATTTTAGGTTATACAAACGAAAAAGACAATATTTATCAAGCGAGTAAAAACGCTCCGGTTATCATCTTTGACGAT
TTCACAACAGCGACCCAATGGGTTGATTTCCCCTTCAAAGTAAAATCAAGCGCCATGAAAATCTTATTCTCAAAAAATCC
TACAATTAATATTAGATTTATCTTTTTTTACATGCAAATTATTCCTTATAATATCGGTGGGGAACATGCAAGGCAGTGGA
TTTCTCGCTATTCACAATTAGAAGTCCCCATCCCACCCCTAGAGATCCAACAAGAGATCGTTAAGATTTTGGACGCTTTC
ACAGAATTAAACACAGAATTAAACACAGAATTAAACACAGAATTAAACACAGAATTAAACACAGAATTAAAAGCGCGCAA
AAAGCAATACGAATATTACCAAAACATGCTTTTAGACTTCAATGACATTAATTCAAACCACAAAGACGCCAAAATGAGCG
CCAAACCCTACCCCAAACGCTTGAAAACCTTACTCCAAACTCTAGCGCCTAAGGGGGTGGAGTTTAGGAAGTTGGGGGAT
ATTGGGGAATTTTATGGCGGACTTGTTGGAAAAAGTAAAAAATCTTTCTCTCAAGGGAATAAATTTTATGTTCCTTATAT
CAATGTTTTTAATAATCCACAACTAGATCTAAATGCTTTAGAAAGCGTTCAAATAGGAGATAAAGAAAAACAAAATACAA
TTCAATTAGGCGATGTGCTTTTTACCGGTTCGTCTGAAAATTTAGAGGATTGTGCGATGTCTTGCGTGGTTACTCAAAAG
ATTGAAAAAGATATTTATCTTAATAGTTTTTGTTTTGGTTTTAGATTTTTTGATAAGAATTTATTTAATCCATCGTTTCT
TAAACATTTTTTAAGAGACTACAATTTTAGGAAAAATATTTCAAAAGTTGCTAATGGTGTAACACGCTTCAATGTTTCAA
AGCAATTACTTTCACAAATAACCATCCCCATCCCACCCCTAGAGATCCAACAAGAGATCGTTAAGATTTTGGATCAGTTT
TCAGCCCTAACCACCGATTTATTAGCCGGTATCCCCGCTGAAATAAAAGCCCGAAAAAAGCAATACGAATATTACCGAGA
AAAACTATTGACTTTCAAACCTCTAACCCCCCACAAAGAAGTTAAAAAATGCTAA

Upstream 100 bases:

>100_bases
GGCGATGTGGGGGTTACGCTTTTGGCCTTAGCCAATTCCATGCGCGCGATGAGGGCTTAAAGCCTTGAATCTATCATCAA
AGAGTTAGAAGGGGAGCCAA

Downstream 100 bases:

>100_bases
AAGCGTTTTTACAATCAATCATAAAAGAGCTTGCGGTAGCAAGTGATATTTTCTAAAAAAAGCGGTCTTTTAGGGGGATC
TAGTTGGGGGTTAATGGGGA

Product: putative type I restriction-modification enzyme specificity subunit S

Products: NA

Alternate protein names: S.EcoR124II; Type I restriction enzyme EcoR124II specificity protein; S protein [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MHKIERLLQTLAPKGVEFRKLGEVLEYDQPNQYCVTSKEFDKSYPTPVLTAGKTFILGYTNEKDNIYQASKNAPVIIFDD
FTTATQWVDFPFKVKSSAMKILFSKNPTINIRFIFFYMQIIPYNIGGEHARQWISRYSQLEVPIPPLEIQQEIVKILDAF
TELNTELNTELNTELNTELNTELKARKKQYEYYQNMLLDFNDINSNHKDAKMSAKPYPKRLKTLLQTLAPKGVEFRKLGD
IGEFYGGLVGKSKKSFSQGNKFYVPYINVFNNPQLDLNALESVQIGDKEKQNTIQLGDVLFTGSSENLEDCAMSCVVTQK
IEKDIYLNSFCFGFRFFDKNLFNPSFLKHFLRDYNFRKNISKVANGVTRFNVSKQLLSQITIPIPPLEIQQEIVKILDQF
SALTTDLLAGIPAEIKARKKQYEYYREKLLTFKPLTPHKEVKKC

Sequences:

>Translated_444_residues
MHKIERLLQTLAPKGVEFRKLGEVLEYDQPNQYCVTSKEFDKSYPTPVLTAGKTFILGYTNEKDNIYQASKNAPVIIFDD
FTTATQWVDFPFKVKSSAMKILFSKNPTINIRFIFFYMQIIPYNIGGEHARQWISRYSQLEVPIPPLEIQQEIVKILDAF
TELNTELNTELNTELNTELNTELKARKKQYEYYQNMLLDFNDINSNHKDAKMSAKPYPKRLKTLLQTLAPKGVEFRKLGD
IGEFYGGLVGKSKKSFSQGNKFYVPYINVFNNPQLDLNALESVQIGDKEKQNTIQLGDVLFTGSSENLEDCAMSCVVTQK
IEKDIYLNSFCFGFRFFDKNLFNPSFLKHFLRDYNFRKNISKVANGVTRFNVSKQLLSQITIPIPPLEIQQEIVKILDQF
SALTTDLLAGIPAEIKARKKQYEYYREKLLTFKPLTPHKEVKKC
>Mature_444_residues
MHKIERLLQTLAPKGVEFRKLGEVLEYDQPNQYCVTSKEFDKSYPTPVLTAGKTFILGYTNEKDNIYQASKNAPVIIFDD
FTTATQWVDFPFKVKSSAMKILFSKNPTINIRFIFFYMQIIPYNIGGEHARQWISRYSQLEVPIPPLEIQQEIVKILDAF
TELNTELNTELNTELNTELNTELKARKKQYEYYQNMLLDFNDINSNHKDAKMSAKPYPKRLKTLLQTLAPKGVEFRKLGD
IGEFYGGLVGKSKKSFSQGNKFYVPYINVFNNPQLDLNALESVQIGDKEKQNTIQLGDVLFTGSSENLEDCAMSCVVTQK
IEKDIYLNSFCFGFRFFDKNLFNPSFLKHFLRDYNFRKNISKVANGVTRFNVSKQLLSQITIPIPPLEIQQEIVKILDQF
SALTTDLLAGIPAEIKARKKQYEYYREKLLTFKPLTPHKEVKKC

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 51370; Mature: 51370

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKIERLLQTLAPKGVEFRKLGEVLEYDQPNQYCVTSKEFDKSYPTPVLTAGKTFILGYT
CCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCHHHCCCCCCCEEECCCEEEEEEE
NEKDNIYQASKNAPVIIFDDFTTATQWVDFPFKVKSSAMKILFSKNPTINIRFIFFYMQI
CCCCCCEECCCCCCEEEEECCCCHHHHCCCCHHHHHHHHEEEECCCCEEEEEEHHEEHHH
IPYNIGGEHARQWISRYSQLEVPIPPLEIQQEIVKILDAFTELNTELNTELNTELNTELN
HCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TELKARKKQYEYYQNMLLDFNDINSNHKDAKMSAKPYPKRLKTLLQTLAPKGVEFRKLGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHCC
IGEFYGGLVGKSKKSFSQGNKFYVPYINVFNNPQLDLNALESVQIGDKEKQNTIQLGDVL
HHHHHHHHHCCCHHHHHCCCEEEEEEEEECCCCCCCHHHHHHCCCCCCCCCCEEEECCEE
FTGSSENLEDCAMSCVVTQKIEKDIYLNSFCFGFRFFDKNLFNPSFLKHFLRDYNFRKNI
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
SKVANGVTRFNVSKQLLSQITIPIPPLEIQQEIVKILDQFSALTTDLLAGIPAEIKARKK
HHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QYEYYREKLLTFKPLTPHKEVKKC
HHHHHHHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure
MHKIERLLQTLAPKGVEFRKLGEVLEYDQPNQYCVTSKEFDKSYPTPVLTAGKTFILGYT
CCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCHHHCCCCCCCEEECCCEEEEEEE
NEKDNIYQASKNAPVIIFDDFTTATQWVDFPFKVKSSAMKILFSKNPTINIRFIFFYMQI
CCCCCCEECCCCCCEEEEECCCCHHHHCCCCHHHHHHHHEEEECCCCEEEEEEHHEEHHH
IPYNIGGEHARQWISRYSQLEVPIPPLEIQQEIVKILDAFTELNTELNTELNTELNTELN
HCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TELKARKKQYEYYQNMLLDFNDINSNHKDAKMSAKPYPKRLKTLLQTLAPKGVEFRKLGD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHCC
IGEFYGGLVGKSKKSFSQGNKFYVPYINVFNNPQLDLNALESVQIGDKEKQNTIQLGDVL
HHHHHHHHHCCCHHHHHCCCEEEEEEEEECCCCCCCHHHHHHCCCCCCCCCCEEEECCEE
FTGSSENLEDCAMSCVVTQKIEKDIYLNSFCFGFRFFDKNLFNPSFLKHFLRDYNFRKNI
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
SKVANGVTRFNVSKQLLSQITIPIPPLEIQQEIVKILDQFSALTTDLLAGIPAEIKARKK
HHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QYEYYREKLLTFKPLTPHKEVKKC
HHHHHHHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]