| Definition | Helicobacter pylori HPAG1 chromosome, complete genome. |
|---|---|
| Accession | NC_008086 |
| Length | 1,596,366 |
Click here to switch to the map view.
The map label for this gene is uvrA [H]
Identifier: 108563115
GI number: 108563115
Start: 724748
End: 727573
Strand: Reverse
Name: uvrA [H]
Synonym: HPAG1_0690
Alternate gene names: 108563115
Gene position: 727573-724748 (Counterclockwise)
Preceding gene: 108563124
Following gene: 108563095
Centisome position: 45.58
GC content: 40.76
Gene sequence:
>2826_bases TTGCAACATAAAACCATTATGGATAAGATCATTATTCAAGGGGCTAGGGAAAATAATCTCAAAAATATTTTTTTAGAAAT CCCTAAAAACCAGTTTGTTGTTTTTACCGGATTAAGCGGTTCGGGTAAATCCACTCTGGCGTTTGACACTTTATACGCTG AAGGCCAAAGGCGCTATTTAGAGAGTTTGTCCAGCTATGCTAGGCAATTTTTAGATAAAGTGGGTAAGCCTAATGTGGAT AAAATTGAAGGCCTAACCCCTGCGATCGCTATTGATCAAAAGACCACTTCTAAAAACCCTAGATCCACTGTGGGGACGAT CACTGAGATTTATGATTATTTAAGGTTGTTGTTTGCAAGGATTGGGGAGCAATTTTGCCCCACATGTTCAGAGCCCATTA GTTCTATGAGCGCGAGCGATATTATTTCTCAAATCTGTCATTTAGAAGAAAATTCTAAAATCATTATTCTTGCCCCCATT ATTAAAGATAAAAAAGGTTCGTTTAACGATAAATTAGAGAGCTTGCGTTTGAAGGGGTATGTGAGGGCTTTTGTTGATGG GGTGATGGTGCGTTTAGATGAAGAAATCCATTTGCACAAAACCAAAAAACACACCATTGAAGCGGTGGTGGATAGAGTGG TTATCAATAGCGAAAATGCTTCACGGATCGCTAGCGCAGTAGAAAAAGCCCTTAAAGAAAGCTATGGGGAATTAGAAGTG GAAATCTTGCAAGACAACGCGCCAAGCATCAGAAAGCATTACAGCGAGCATAAGGCATGCTTTAAATGCAAGATGAGTTT TGAAGAATTAGAGCCTTTGAGTTTTTCCTTCAATTCGCCTAAAGGGGCGTGCGAGAGCTGTTTGGGTTTAGGGACAAAAT TCAGTTTAGACATTAGTAAGATTTTAGATCCTAACACGCCTTTAAATCAAGGAGCGATTAAAGTGATTTTTGGGTATAAC CGCAGTTATTACGCTCAAATGTTTGAAGGCTTTTGCGCTTATAATGGCATTGACAGCGCGCTTTGTTTTAACGAATTGAA TAAAGAGCAACAGGACGCTCTTTTATATGGGAATGGCACTGAAATCAGCTTTCATTTTAAAAACAGCCCTTTAAAACGCC CTTGGAAAGGCATTATCCAAATCGCTTATGACATGTTTAAAGAGCAAAAGGATTTGAGCGATTACATGAGCGAAAAAACC TGTTCTTCGTGCAAGGGGCATCGTTTGAAAGTCTCCAGTTTGAGCGTCCAAGTCGCCGGCTTGAAAATGGCGGATTTTTT AACTAAGCCCATTGAAGAAGTCTATCATTTTTTTAATGATCCCACGCATTTTAGCTATCTTAACGAGCAAGAAAAAAAGA TCGCTGAACCCATTTTAAAAGAGATTTTAGAAAGGGTGTTTTTTTTATACGATGTGGGGCTAGGGTATTTGACTTTAGGG AGGGATGCGCGAACGATTAGCGGAGGGGAGAGTCAAAGGATACGAATCGCTAGTCAAATCGGGAGTGGCTTGACAGGGGT TTTGTATGTTTTAGACGAGCCTAGCATTGGCTTGCATGAAAAAGACACGCTCAAACTCATCAACACCCTTAGGAATTTAC AAAAAAAGGGGAACACGCTCATTGTCGTAGAGCATGATAAAGAGACGATTAAGCATGCGGATTTTGTTGTGGATATTGGA CCAAAGGCTGGAAGGCATGGGGGTGAAGTGGTTTTTAGCGGGAGCGTGAAAGAGTTATTGCAGAATAACCATTCTACCGC CTTGTATCTCAACGGCACTAAAAAGATTGAGCGCCCTAAATTTGAACTCCCTAAAGAAAAGCATTTTTTAGAAATCAAAA ATGTCAATATCAATAACATTAGGAATTTGAGCGTTCAAATCCCTTTAAAACAATTGGTGTGCATTACTGGGGTGAGCGGG AGCGGTAAAAGCTCGCTGATTTTACAAACCCTTTTACCCACCGCTCAAACCCTTTTAAACCATGCTAAAAAAACTCAAAG CTTGAATGGGGTGGAGATTGTAGGGTTGGAGCATTTGGATAAAGTGATTTATTTAGACCAAGCCCCCATAGGCAAAACCC CACGAAGCAACCCTGCCACTTACACGGGAGTGATGGATGAAATCAGGATTTTATTTGCCGAGCAAAAAGAAGCTAAAATT TTAGGCTATAGCGCGAGCCGTTTCAGCTTTAATGTTAAAGGGGGGCGGTGCGAGAAATGCCAAGGCGATGGGGATATTAA AATAGAAATGCACTTTTTGCCTGATGTGTTAGTCCAATGCGATAGCTGTAAGGGCGCTAAATACAACCCTCAAACTCTAG AAATCAAGGTGAAAGGCAAATCTATTGCTGATGTGTTGAACATGAGCGTAGAAGAGGCTTATGAGTTTTTTGCTAAATTC CCTAAAATCGCTGTGAAGTTAAAAACGCTTATAGATGTGGGCTTGGGCTATATCACTTTAGGGCAAAACGCTACGACTTT AAGCGGGGGGGAGGCTCAAAGGATCAAATTGGCTAAAGAATTGAGTAAAAAAGACACAGGCAAAACCCTTTATATTTTAG ATGAGCCTACCACCGGTTTGCATTTTGAAGACGTGAATCACCTTTTACAAGTCTTGCATTCTTTAGTAGCGTTAGGCAAT TCCATGCTAGTGATTGAGCATAATTTAGACATTATCAAAAACGCTGACTACATTATAGACATGGGGCCTGATGGGGGGGA TAAGGGCGGGAAAGTCATTGCGAGCGGCACGCCTTTAGAGGTGGCGCAAAATTGCGAAAAAACCCAAAGCTATACGGGAA AATTTTTAGCTTTAGAATTGAAATAG
Upstream 100 bases:
>100_bases AAATATTTTTAACTCTTATGAATAAGAAATGATAATAAAACCATTCTTTTTTGAAGTATAATAGCTCCTTTTAATCCATT TTCTTATTTTAAGGAAACTC
Downstream 100 bases:
>100_bases CTTGATCATGCAAGAGTTAGCAAAGAAGCCATGCCTTTAAAATCCTCGCATGAAAGTTTGAAAGAACGGCTTTATTATTA TTAAGTGTTAATCATAAATT
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 941; Mature: 941
Protein sequence:
>941_residues MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVD KIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARIGEQFCPTCSEPISSMSASDIISQICHLEENSKIIILAPI IKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENASRIASAVEKALKESYGELEV EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYN RSYYAQMFEGFCAYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKT CSSCKGHRLKVSSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIG PKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIRNLSVQIPLKQLVCITGVSG SGKSSLILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKF PKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGN SMLVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
Sequences:
>Translated_941_residues MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVD KIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARIGEQFCPTCSEPISSMSASDIISQICHLEENSKIIILAPI IKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENASRIASAVEKALKESYGELEV EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYN RSYYAQMFEGFCAYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKT CSSCKGHRLKVSSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIG PKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIRNLSVQIPLKQLVCITGVSG SGKSSLILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKF PKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGN SMLVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK >Mature_941_residues MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVD KIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARIGEQFCPTCSEPISSMSASDIISQICHLEENSKIIILAPI IKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENASRIASAVEKALKESYGELEV EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYN RSYYAQMFEGFCAYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKT CSSCKGHRLKVSSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIG PKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIRNLSVQIPLKQLVCITGVSG SGKSSLILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKF PKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGN SMLVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=947, Percent_Identity=51.1087645195354, Blast_Score=905, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104711; Mature: 104711
Theoretical pI: Translated: 8.01; Mature: 8.01
Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYL CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH ESLSSYARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFAR HHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH IGEQFCPTCSEPISSMSASDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGY HHHHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH VRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENASRIASAVEKALKESYGELEV HHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEE EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISK EEEECCCCHHHHHHHHHHHHHHEECCHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEHHH ILDPNTPLNQGAIKVIFGYNRSYYAQMFEGFCAYNGIDSALCFNELNKEQQDALLYGNGT HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCC EISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCKGHRLKVSSLSVQVAG EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEC LKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG CHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTL CCCCCCCCCCCCEEEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEE IVVEHDKETIKHADFVVDIGPKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPK EEEECCHHHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHHCCCCEEEEECCCCCCCCCC FELPKEKHFLEIKNVNINNIRNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLN CCCCCCCCEEEEECCCCCCEEEEEEEECHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHH HAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI HHHHHCCCCCEEEEEHHHHCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEE LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGK EEEECCEEEEECCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEEEEECCC SIADVLNMSVEEAYEFFAKFPKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKE HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHH LSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIEHNLDIIKNADYIID HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEE MGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK ECCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEC >Mature Secondary Structure MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYL CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH ESLSSYARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFAR HHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH IGEQFCPTCSEPISSMSASDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGY HHHHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH VRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENASRIASAVEKALKESYGELEV HHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEE EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISK EEEECCCCHHHHHHHHHHHHHHEECCHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEHHH ILDPNTPLNQGAIKVIFGYNRSYYAQMFEGFCAYNGIDSALCFNELNKEQQDALLYGNGT HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCC EISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCKGHRLKVSSLSVQVAG EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEC LKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG CHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTL CCCCCCCCCCCCEEEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEE IVVEHDKETIKHADFVVDIGPKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPK EEEECCHHHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHHCCCCEEEEECCCCCCCCCC FELPKEKHFLEIKNVNINNIRNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLN CCCCCCCCEEEEECCCCCCEEEEEEEECHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHH HAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI HHHHHCCCCCEEEEEHHHHCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEE LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGK EEEECCEEEEECCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEEEEECCC SIADVLNMSVEEAYEFFAKFPKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKE HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHH LSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIEHNLDIIKNADYIID HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEE MGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK ECCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]