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The map label for this gene is atoC [H]

Identifier: 108563113

GI number: 108563113

Start: 722702

End: 723847

Strand: Direct

Name: atoC [H]

Synonym: HPAG1_0688

Alternate gene names: 108563113

Gene position: 722702-723847 (Clockwise)

Preceding gene: 108563112

Following gene: 108563114

Centisome position: 45.27

GC content: 40.05

Gene sequence:

>1146_bases
ATGAAAATCGCCATTGTAGAAGATGATATCAACATGCGTAAAAGCCTGGAGCTTTTTTTTGAGCTTCAAGACGATTTAGA
GATTGTGAGTTTTAAAAACCCTAAAGACGCTTTAGCCAAGTTAGATGAAAGCTTTGATTTAGTCATCACGGATATTAACA
TGCCCCATATGGACGGCTTGGAATTTTTACGCCTTTTAGAGGGCAAATATGAATCCATTGTGATTACCGGTAATGCGACC
TTGAATAAAGCCATTGATTCCATTCGTTTAGGCGTGAAAGACTTTTTCCAAAAACCTTTTAAACCAGAATTGCTTTTAGA
ATCCATCTATCGCACTAAAAAAGTTTTAGAATTTCAAAAAAAACACCCTCTAGAAAAACCTTTAAAAAAACCACACAAAC
ACAGCTTTTTAGCCGCTTCAAAAGCGTTAGAAGAAAGCAAACGGCAGGCCTTAAAAGTCGCAAGCACGGACGCTAATGTC
ATGCTATTAGGCGAAAGCGGGGTGGGTAAGGAGGTTTTTGCTCATTTCATCCACCAGCATTCGCATCGCTCCAAACACCC
TTTTATCGCAATCAACATGTCCGCAATCCCAGAGCATTTATTAGAAAGCGAGCTTTTTGGGTATCAAAAAGGGGCGTTCA
CGGACGCCACAGCCCCTAAAATGGGACTTTTTGAAAGCGCTAATAAAGGCACGATCTTTTTAGATGAAATCGCTGAAATG
CCCTTTCAATTGCAAAGCAAACTTTTAAGAGTGGTTCAAGAAAAAGAAATCACGCGCCTTGGGGATAATAAGAGCGTTAA
AATTGATGTTCGTTTCATTTCCGCTACCAACGCTAACATGAAAGAAAAAATCGCTGCGAAAGAATTTAGAGAAGATTTAT
TTTTCCGCTTGCAAATCGTGCCTATAACTATCGCGCCTTTAAGAGAGAGGGTAGAAGAGATTTTACCCATTGCTGAAATC
AAGCTTAAAGAAGTGTGCGATGCGTATCATTTGGGGCCAAAATCTTTTTCAAAAAACGCCGCAAAACGCCTTTTAGAATA
TTCTTGGCATGGGAATGTGCGAGAGCTTTTAGGCGTCGTGGAAAGAGCGGCGATTTTAAGCGAAGGAGCAGAAATCCAAG
AGAAAGATTTGTTTTTGGAAAGGTAG

Upstream 100 bases:

>100_bases
GCACCACTACCACAAGCATACTTGATCTCAAAGCCTTAAGCGTTAGAGCGAGTTTAGTGGGAGATGCGCTGTTTTTAGAT
ATTTTTAGAAAGGAAGAAGA

Downstream 100 bases:

>100_bases
TTTGTAAGGCTTCTTTATAAATCATCTGCAACCAGATAAGTTTAATAAGTTTTAGTGATCACGCTATAATTTCATGGAGT
TATTAAAGGCTGATAAGGAA

Product: transcriptional activator of flagella proteins

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIAIVEDDINMRKSLELFFELQDDLEIVSFKNPKDALAKLDESFDLVITDINMPHMDGLEFLRLLEGKYESIVITGNAT
LNKAIDSIRLGVKDFFQKPFKPELLLESIYRTKKVLEFQKKHPLEKPLKKPHKHSFLAASKALEESKRQALKVASTDANV
MLLGESGVGKEVFAHFIHQHSHRSKHPFIAINMSAIPEHLLESELFGYQKGAFTDATAPKMGLFESANKGTIFLDEIAEM
PFQLQSKLLRVVQEKEITRLGDNKSVKIDVRFISATNANMKEKIAAKEFREDLFFRLQIVPITIAPLRERVEEILPIAEI
KLKEVCDAYHLGPKSFSKNAAKRLLEYSWHGNVRELLGVVERAAILSEGAEIQEKDLFLER

Sequences:

>Translated_381_residues
MKIAIVEDDINMRKSLELFFELQDDLEIVSFKNPKDALAKLDESFDLVITDINMPHMDGLEFLRLLEGKYESIVITGNAT
LNKAIDSIRLGVKDFFQKPFKPELLLESIYRTKKVLEFQKKHPLEKPLKKPHKHSFLAASKALEESKRQALKVASTDANV
MLLGESGVGKEVFAHFIHQHSHRSKHPFIAINMSAIPEHLLESELFGYQKGAFTDATAPKMGLFESANKGTIFLDEIAEM
PFQLQSKLLRVVQEKEITRLGDNKSVKIDVRFISATNANMKEKIAAKEFREDLFFRLQIVPITIAPLRERVEEILPIAEI
KLKEVCDAYHLGPKSFSKNAAKRLLEYSWHGNVRELLGVVERAAILSEGAEIQEKDLFLER
>Mature_381_residues
MKIAIVEDDINMRKSLELFFELQDDLEIVSFKNPKDALAKLDESFDLVITDINMPHMDGLEFLRLLEGKYESIVITGNAT
LNKAIDSIRLGVKDFFQKPFKPELLLESIYRTKKVLEFQKKHPLEKPLKKPHKHSFLAASKALEESKRQALKVASTDANV
MLLGESGVGKEVFAHFIHQHSHRSKHPFIAINMSAIPEHLLESELFGYQKGAFTDATAPKMGLFESANKGTIFLDEIAEM
PFQLQSKLLRVVQEKEITRLGDNKSVKIDVRFISATNANMKEKIAAKEFREDLFFRLQIVPITIAPLRERVEEILPIAEI
KLKEVCDAYHLGPKSFSKNAAKRLLEYSWHGNVRELLGVVERAAILSEGAEIQEKDLFLER

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=383, Percent_Identity=38.9033942558747, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1788905, Length=351, Percent_Identity=38.1766381766382, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1790299, Length=380, Percent_Identity=34.7368421052632, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1790437, Length=383, Percent_Identity=33.9425587467363, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI87082117, Length=230, Percent_Identity=44.7826086956522, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1789233, Length=254, Percent_Identity=42.5196850393701, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789087, Length=238, Percent_Identity=43.2773109243698, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1786524, Length=243, Percent_Identity=44.0329218106996, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082152, Length=253, Percent_Identity=39.9209486166008, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=40.1709401709402, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787583, Length=244, Percent_Identity=35.655737704918, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87081858, Length=218, Percent_Identity=33.9449541284404, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=31.2757201646091, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 43409; Mature: 43409

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVEDDINMRKSLELFFELQDDLEIVSFKNPKDALAKLDESFDLVITDINMPHMDGL
CEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCHH
EFLRLLEGKYESIVITGNATLNKAIDSIRLGVKDFFQKPFKPELLLESIYRTKKVLEFQK
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KHPLEKPLKKPHKHSFLAASKALEESKRQALKVASTDANVMLLGESGVGKEVFAHFIHQH
HCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
SHRSKHPFIAINMSAIPEHLLESELFGYQKGAFTDATAPKMGLFESANKGTIFLDEIAEM
CCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHC
PFQLQSKLLRVVQEKEITRLGDNKSVKIDVRFISATNANMKEKIAAKEFREDLFFRLQIV
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHEEEEEEE
PITIAPLRERVEEILPIAEIKLKEVCDAYHLGPKSFSKNAAKRLLEYSWHGNVRELLGVV
EEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ERAAILSEGAEIQEKDLFLER
HHHHHHHCCCCCCHHHCCCCC
>Mature Secondary Structure
MKIAIVEDDINMRKSLELFFELQDDLEIVSFKNPKDALAKLDESFDLVITDINMPHMDGL
CEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCEEEEECCCCCCCHH
EFLRLLEGKYESIVITGNATLNKAIDSIRLGVKDFFQKPFKPELLLESIYRTKKVLEFQK
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KHPLEKPLKKPHKHSFLAASKALEESKRQALKVASTDANVMLLGESGVGKEVFAHFIHQH
HCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
SHRSKHPFIAINMSAIPEHLLESELFGYQKGAFTDATAPKMGLFESANKGTIFLDEIAEM
CCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHC
PFQLQSKLLRVVQEKEITRLGDNKSVKIDVRFISATNANMKEKIAAKEFREDLFFRLQIV
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHEEEEEEE
PITIAPLRERVEEILPIAEIKLKEVCDAYHLGPKSFSKNAAKRLLEYSWHGNVRELLGVV
EEEHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ERAAILSEGAEIQEKDLFLER
HHHHHHHCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]