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The map label for this gene is serB [C]

Identifier: 108563062

GI number: 108563062

Start: 662721

End: 663344

Strand: Reverse

Name: serB [C]

Synonym: HPAG1_0637

Alternate gene names: 108563062

Gene position: 663344-662721 (Counterclockwise)

Preceding gene: 108563063

Following gene: 108563061

Centisome position: 41.55

GC content: 41.03

Gene sequence:

>624_bases
GTGCAAAAACTAGCCGTTTTTGATTTTGACTCCACGCTAGTCAATGCTGAGACGATTGAGTCTTTAGCGAGAGCGTGGGG
GGTGTTTGATGAAGTGAAAACAATCACTTCGCAAGCCATGAATGGCGAGACAGATTTTCATAAAAGTCTTATTTTAAGGG
TTTCTAAACTCAAAAACATGCCTTTAAAACTAGCCAAAGAAGTTTGTGAAAGTCTGCCTTTGTTTGAGGGGGCGTTTGAT
CTCATTAGCGCCTTAAAAGAGAAAAATTACAAAGTGGTTTGCTTTAGTGGGGGCTTTGATCTAGCGACGAATTATTATAG
GGATTTATTGAATTTAGATGCGGCTTTCAGTAACACGCTGGTAGTGGAAAATGACGCCTTAAACGGCTTGGTTACCGGGC
ATATGATGTTTTCACACTCTAAAGGCGAAATGCTCCTCGCCTTGCAACGCTTATTGAATATCAGTAAAGATCGCACTCTA
GTGGTGGGCGATGGAGCGAATGACTTGAGCATGTTCAAACATGCCCATATCAAAATCGCTTTCAACGCTAAAGAGATTTT
AAAACAACACGCCACGCATTGCATCAATGAGCCTAATTTAGCTCTAATCAAGCCTTTGATTTAA

Upstream 100 bases:

>100_bases
AAATTGAGTTGATTGGTAATGAAAACCATGGCTTGTATTTGGCTGATCAGTATGTCAAAGGGATCGCTAAAAGCAGGAAA
TCTTAATTTTAGGGTATTGG

Downstream 100 bases:

>100_bases
AAAAATTTTTTTGTAAAATACTCCTTTTAAAGGATAGCCATGTTCCAACCCTTACTAGACGCCTTTATAGAAAGCACTCC
AATTAAAAAAAAATTACCTC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITSQAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGAFD
LISALKEKNYKVVCFSGGFDLATNYYRDLLNLDAAFSNTLVVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKDRTL
VVGDGANDLSMFKHAHIKIAFNAKEILKQHATHCINEPNLALIKPLI

Sequences:

>Translated_207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITSQAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGAFD
LISALKEKNYKVVCFSGGFDLATNYYRDLLNLDAAFSNTLVVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKDRTL
VVGDGANDLSMFKHAHIKIAFNAKEILKQHATHCINEPNLALIKPLI
>Mature_207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITSQAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGAFD
LISALKEKNYKVVCFSGGFDLATNYYRDLLNLDAAFSNTLVVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKDRTL
VVGDGANDLSMFKHAHIKIAFNAKEILKQHATHCINEPNLALIKPLI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=191, Percent_Identity=30.3664921465969, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1790849, Length=197, Percent_Identity=36.0406091370558, Blast_Score=118, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6321647, Length=204, Percent_Identity=36.7647058823529, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23029; Mature: 23029

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITSQAMNGETDFHKSLILRVSKLKNM
CCCEEEEECCCHHCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
PLKLAKEVCESLPLFEGAFDLISALKEKNYKVVCFSGGFDLATNYYRDLLNLDAAFSNTL
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCE
VVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKDRTLVVGDGANDLSMFKHAHIKIA
EEECCCCCCEEEHHEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHEEEEEE
FNAKEILKQHATHCINEPNLALIKPLI
ECHHHHHHHHHHHHCCCCCHHCCCCCC
>Mature Secondary Structure
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITSQAMNGETDFHKSLILRVSKLKNM
CCCEEEEECCCHHCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
PLKLAKEVCESLPLFEGAFDLISALKEKNYKVVCFSGGFDLATNYYRDLLNLDAAFSNTL
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCE
VVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKDRTLVVGDGANDLSMFKHAHIKIA
EEECCCCCCEEEHHEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHEEEEEE
FNAKEILKQHATHCINEPNLALIKPLI
ECHHHHHHHHHHHHCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]