Click here to switch to the map view.

The map label for this gene is dapL [H]

Identifier: 108563032

GI number: 108563032

Start: 634158

End: 635285

Strand: Reverse

Name: dapL [H]

Synonym: HPAG1_0607

Alternate gene names: 108563032

Gene position: 635285-634158 (Counterclockwise)

Preceding gene: 108563038

Following gene: 108563031

Centisome position: 39.8

GC content: 39.36

Gene sequence:

>1128_bases
ATGACCTTTGAGCCTTATCCTTTTGAACGATTAAGAGCCTTGTTTAAAGAGATCACCCCTAAAAAAAAGGGGCTAGATCT
AGGCATCGGCGAGCCGCGATTTGAAACGCCCAAATTCATTCAAGACGCCCTCAAAAACCACACCCATTCGCTCAATATCT
ACCCTAAAAGCGCGTTTGAAGAGAGTTTGAGAGAGGCTCAAAGGGGTTTTTTTAAACGCCGTTTCAAGATAGAATTGAAA
GAAAACGAACTAGTTTCCACGCTAGGATCTAGGGAAGTGTTATTCAATTTCCCTAGTTTTGTTTTATTTGATTACCAAAA
CCCCACTATCGCCTACCCTAACCCCTTTTATCAAATCTATGAAGGAGCGGCTAAATTTATCAAAGCTAAAAGCCTTTTAA
TGCCCTTAACTAAAGAAAATGATTTCACGCCAAGCTTGAATGAAAAAGAGTTGCAAGAAGTGGATTTAGTGATCTTAAAT
TCCCCTAACAACCCCACCGGAAGAACCCTTTCTTTAGAAGAACTGATTAGTTGGGTCAAACTCGCTTTAAAACATGATTT
TATTTTAATTAATGATGAATGCTATAGTGAAATTTATGAAAATACGCCTCCCCCTTCGCTTTTAGAAGCTTGCAAGCTTA
TTGGTAATGAAGCGTTTAAAAATGTTTTGGTTATCCATTCGCTCTCCAAACGCTCTAGCGCTCCAGGACTAAGGAGTGGT
TTTATCGCTGGGGATAGCAGCCTTTTAGAAAAATACAAAGCGTTTCGCACCTATTTAGGCTATACGAGTGCTAATGCGAT
CCAAAAGGCTAGTGAAGCGGCCTGGCTAGATGATAGGCATGCAGAATTTTTCCGCAATATTTATGCGAATAATTTGAAAC
TAGCGCGAAAAATCTTTAAAAACACGCTCATTTATCCTTTTAGTTTTTATGTGTATCTGCCCGTTCAAAACGGCGAAAAT
TTTGCTAAAAGACTTTATCAAAATGAAGGCATTATTACTTTACCGGCCTTGTATTTAGGGCGTAATCGTATCGGCGCTGA
TTGCGTGCGTTTAGCCCTTGTCTATGACACCCCCCTTTTAGAAAAGCCTTTAGAAATCATAGAAACTTATCGAGAAAACC
ATGCTTGA

Upstream 100 bases:

>100_bases
AATTCTTATGTGCTATTATACTCTTTCTTGGTGGTTTCATACCATAACGCTTAAATTTTAGGTAAGATTAACTATTCCAT
TTTAAGATTAAAGTAGCCCT

Downstream 100 bases:

>100_bases
AACCCCAAAAGTTTTACTCAAAAACCTGCAAGATTGCAAGATCCATTTTATCGGTATAGGGGGGATTGGCATTTCAGGCT
TAGCCAAATACCTTAAAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKNHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELK
ENELVSTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSLLMPLTKENDFTPSLNEKELQEVDLVILN
SPNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACKLIGNEAFKNVLVIHSLSKRSSAPGLRSG
FIAGDSSLLEKYKAFRTYLGYTSANAIQKASEAAWLDDRHAEFFRNIYANNLKLARKIFKNTLIYPFSFYVYLPVQNGEN
FAKRLYQNEGIITLPALYLGRNRIGADCVRLALVYDTPLLEKPLEIIETYRENHA

Sequences:

>Translated_375_residues
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKNHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELK
ENELVSTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSLLMPLTKENDFTPSLNEKELQEVDLVILN
SPNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACKLIGNEAFKNVLVIHSLSKRSSAPGLRSG
FIAGDSSLLEKYKAFRTYLGYTSANAIQKASEAAWLDDRHAEFFRNIYANNLKLARKIFKNTLIYPFSFYVYLPVQNGEN
FAKRLYQNEGIITLPALYLGRNRIGADCVRLALVYDTPLLEKPLEIIETYRENHA
>Mature_374_residues
TFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKNHTHSLNIYPKSAFEESLREAQRGFFKRRFKIELKE
NELVSTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSLLMPLTKENDFTPSLNEKELQEVDLVILNS
PNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACKLIGNEAFKNVLVIHSLSKRSSAPGLRSGF
IAGDSSLLEKYKAFRTYLGYTSANAIQKASEAAWLDDRHAEFFRNIYANNLKLARKIFKNTLIYPFSFYVYLPVQNGENF
AKRLYQNEGIITLPALYLGRNRIGADCVRLALVYDTPLLEKPLEIIETYRENHA

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=287, Percent_Identity=25.4355400696864, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI56713254, Length=287, Percent_Identity=25.4355400696864, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=26.0869565217391, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=302, Percent_Identity=24.5033112582781, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=302, Percent_Identity=24.5033112582781, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=285, Percent_Identity=24.2105263157895, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=297, Percent_Identity=23.2323232323232, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43182; Mature: 43051

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS01037 SBP_BACTERIAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKNHTHSLNIYPKSAFE
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHH
ESLREAQRGFFKRRFKIELKENELVSTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIY
HHHHHHHHHHHHHHEEEEECHHHHHHHCCCCHHEEECCCEEEEECCCCEEECCCHHHHHH
EGAAKFIKAKSLLMPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELISWVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEHHHHHHHHH
LALKHDFILINDECYSEIYENTPPPSLLEACKLIGNEAFKNVLVIHSLSKRSSAPGLRSG
HHHHCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCC
FIAGDSSLLEKYKAFRTYLGYTSANAIQKASEAAWLDDRHAEFFRNIYANNLKLARKIFK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NTLIYPFSFYVYLPVQNGENFAKRLYQNEGIITLPALYLGRNRIGADCVRLALVYDTPLL
CCEEEEEEEEEEEEECCCHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHHHHHHCCCHH
EKPLEIIETYRENHA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFEPYPFERLRALFKEITPKKKGLDLGIGEPRFETPKFIQDALKNHTHSLNIYPKSAFE
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHH
ESLREAQRGFFKRRFKIELKENELVSTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIY
HHHHHHHHHHHHHHEEEEECHHHHHHHCCCCHHEEECCCEEEEECCCCEEECCCHHHHHH
EGAAKFIKAKSLLMPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELISWVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCCCCCEEEHHHHHHHHH
LALKHDFILINDECYSEIYENTPPPSLLEACKLIGNEAFKNVLVIHSLSKRSSAPGLRSG
HHHHCCEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCC
FIAGDSSLLEKYKAFRTYLGYTSANAIQKASEAAWLDDRHAEFFRNIYANNLKLARKIFK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
NTLIYPFSFYVYLPVQNGENFAKRLYQNEGIITLPALYLGRNRIGADCVRLALVYDTPLL
CCEEEEEEEEEEEEECCCHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHHHHHHCCCHH
EKPLEIIETYRENHA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA