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The map label for this gene is mutSB [H]

Identifier: 108563029

GI number: 108563029

Start: 630187

End: 632493

Strand: Reverse

Name: mutSB [H]

Synonym: HPAG1_0604

Alternate gene names: 108563029

Gene position: 632493-630187 (Counterclockwise)

Preceding gene: 108563030

Following gene: 108563021

Centisome position: 39.62

GC content: 37.97

Gene sequence:

>2307_bases
TTGTCAGACGCTTCAAAAAGATCCCTTAATCCAACCCCAATGAACCCCCCAATGATAAATAATAATAATAATAACACCCC
ACCCAAACCCCTAGAAGAAAGTCTGGATTTAAAAGAGTTTATCGCTCTTTTTAAAACTTTTTTTGCTAAAGAAAGAGATA
CTATTGCTTTAGAAAACGATCTCAAGCAAACTTTCACTTATTTAAACGAAGTGGATGCGATCGGGTTGCCTACCCCTAAA
AGCGTGAAAGAAAGCGATCTCATTGTTATCAAACTCACCAAATTAGGGACGCTCCATTTAGATGAAATTTTTGAGATTGT
CAAACGATTGCGCTACATTGTCGTTTTACAAAACGCTTTTAAAACTTTCACGCATTTAAAATTTCATGAACGCCTTAACG
CCATTATTTTACCCCCTTTTTTTAACGACCTGATCGCTTTATTAGATGATGAAGGCAAAATCAAACAAGGGGCGAACGCT
ACCCTAGACGCTTTGAATGAAAGTTTGAACCGCCTTAAAAAAGAGAGCGCAAAAATCATTCACCATTACGCCCGCTCTAA
AGAGCTTGCCCCTTATTTAGTGGATACGCAAAGCCACCTTAAGCATGGTCATGAATGCCTTTTATTAAAGAGCGGGTTTT
CTAGCGCGATTAAGGGCGTTGTGCTAGAAAGGAGTGCTAATGGTTATTTCTATCTTTTGCCTGAAAGCGCCCAAAAAATC
GCGCAAAAAATCGCACAAATTGGTAATGAAATAGATTGCTGTATTGTTGAAATATGTCAAACTCTAAGCCGTAGCTTGCA
AAAACACCTTTTATTTTTAAAATTCCTTTTTAAAGAATTTGATTTTTTAGACAGCTTGCAAGCCAGACTCAATTTTGCTA
AAGCTTATAATTTAGAATTTGTCATGCCAAGCTTTACGCAAAAAAAAATGGTTTTAGAAAACTTTTCGCACCCCATTTTG
AAAGAGCCAAAGCCCTTAAATTTGAAGTTTGAAAAATCCATGCTCGCTGTTACCGGCGTGAATGCGGGCGGGAAAACCAT
GCTCTTAAAATCGCTTTTAAGTGCGGCTTTTTTAAGCAAGCATCTCATTCCTATGAAAATCAACGCCCATCATTCCATTA
TCCCCTATTTTAAAGAAATCCACGCCATTATTAATGACCCCCAAAACAGCGCGAACAATATCTCTACTTTTGCCGGCAGA
ATGAAGCAATTTAGCGCTCTTTTATCCAAAGAAAACATGCTTTTAGGCGTTGATGAAATTGAGCTAGGGACTGACGCTGA
TGAAGCGAGCAGCTTGTATAAAACCCTGTTGGAAAAATTGCTTAAACAAAACAACAAAATCGTTATCACCACGCACCACA
AACGCTTGAGCGTATTAATGGCAGAAAATAAGGAAGTGGAATTACTAGCCGCTCTTTATGACGAAGAAAAAGAACGGCCC
ACTTACACTTTTTTAAAAGGGGTTATTGGCAAAAGCTATGCGTTTGAAACCGCTTTACGCTATGGCGTGCCGCATTTTTT
GATTGAAAAAGCGAAAGCCTTTTATGGCGAAGATAAGGAAAAATTGAATGTTTTGATTGAAAATTCCAGCGCGCTAGAAA
GAGAATTAAAACAAAAAAATGAAAGCTTAGAGAACGCTTTAAAAGAGCAAGAAGATTTAAAAAACGCATGGCTTTTAGAA
ATGGAAAAACAAAAAGAAATCTTTCACCATAAAAAATTGGAATTGGAAAAATCCTACCAACAAGCCCTAAATATCTTAAA
AAGCGAAGTCGCTTCAAAAGATACCAGCTCCATGCATAAAAAAATCCATAAAGCGAGCGAAATTTTAAACAAGCATAAAA
CAAACCAGGAAATCCCACAAATCATAACAAGTTTTCAAATTAACGAAAAAGCGCGCTATAAAAATGAAAGCGTGCTGATA
GCACAAATTTTAGATAAGGGCTATTATTTGGTAGAAACCGAGCTTGGAATGCGCTTAAAAGCGCATGGGAGTTGGTTGAA
ACAAATCCAAAAACCCCCTAAAAACAAATTCAAACCCCCTAAAACAACCATCCCTAAACCTAAAAAGGCGAGCTTGCACC
TTGATTTAAGGGGGCAACGCAGCGAAGAAGCCCTGGATTTACTAGACGCTTTTTTAAACGATGCGCTTTTAGGGGGCTTT
GAAGAAGTGCTTATTTGCCACGGCAAGGGGAGCGGGATTTTAGAAAAGTTTGTGAAAGAATTTTTAAAAAACCACCCCAA
AGTGGTAAGCTTTAGCGACGCTCCCATTAATTTAGGTGGCAGTGGGGTTAAAATCGTTAAATTGTAG

Upstream 100 bases:

>100_bases
TTAAAGTGAATAACCAAACCTTTAATTTAGTGAGCGGGACTTTGAGCTTTTTAGGCAAAAAACAAACCCCTATGAAAGAC
GTTCTTGTGGATTTGGATTC

Downstream 100 bases:

>100_bases
TTTTTGGCGCTTTTTTATGGGGGATTAATATAAAAATCCGCTTTTAAACTATAAAGCCATTTCACACCAACGCCCGATGA
GAACAAAGCCTTTTTAAAAG

Product: recombination and DNA strand exchange inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MSDASKRSLNPTPMNPPMINNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPK
SVKESDLIVIKLTKLGTLHLDEIFEIVKRLRYIVVLQNAFKTFTHLKFHERLNAIILPPFFNDLIALLDDEGKIKQGANA
TLDALNESLNRLKKESAKIIHHYARSKELAPYLVDTQSHLKHGHECLLLKSGFSSAIKGVVLERSANGYFYLLPESAQKI
AQKIAQIGNEIDCCIVEICQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPIL
KEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGR
MKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNKIVITTHHKRLSVLMAENKEVELLAALYDEEKERP
TYTFLKGVIGKSYAFETALRYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNESLENALKEQEDLKNAWLLE
MEKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHKKIHKASEILNKHKTNQEIPQIITSFQINEKARYKNESVLI
AQILDKGYYLVETELGMRLKAHGSWLKQIQKPPKNKFKPPKTTIPKPKKASLHLDLRGQRSEEALDLLDAFLNDALLGGF
EEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL

Sequences:

>Translated_768_residues
MSDASKRSLNPTPMNPPMINNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPK
SVKESDLIVIKLTKLGTLHLDEIFEIVKRLRYIVVLQNAFKTFTHLKFHERLNAIILPPFFNDLIALLDDEGKIKQGANA
TLDALNESLNRLKKESAKIIHHYARSKELAPYLVDTQSHLKHGHECLLLKSGFSSAIKGVVLERSANGYFYLLPESAQKI
AQKIAQIGNEIDCCIVEICQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPIL
KEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGR
MKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNKIVITTHHKRLSVLMAENKEVELLAALYDEEKERP
TYTFLKGVIGKSYAFETALRYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNESLENALKEQEDLKNAWLLE
MEKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHKKIHKASEILNKHKTNQEIPQIITSFQINEKARYKNESVLI
AQILDKGYYLVETELGMRLKAHGSWLKQIQKPPKNKFKPPKTTIPKPKKASLHLDLRGQRSEEALDLLDAFLNDALLGGF
EEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
>Mature_767_residues
SDASKRSLNPTPMNPPMINNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKS
VKESDLIVIKLTKLGTLHLDEIFEIVKRLRYIVVLQNAFKTFTHLKFHERLNAIILPPFFNDLIALLDDEGKIKQGANAT
LDALNESLNRLKKESAKIIHHYARSKELAPYLVDTQSHLKHGHECLLLKSGFSSAIKGVVLERSANGYFYLLPESAQKIA
QKIAQIGNEIDCCIVEICQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILK
EPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRM
KQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNKIVITTHHKRLSVLMAENKEVELLAALYDEEKERPT
YTFLKGVIGKSYAFETALRYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNESLENALKEQEDLKNAWLLEM
EKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHKKIHKASEILNKHKTNQEIPQIITSFQINEKARYKNESVLIA
QILDKGYYLVETELGMRLKAHGSWLKQIQKPPKNKFKPPKTTIPKPKKASLHLDLRGQRSEEALDLLDAFLNDALLGGFE
EVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL

Specific function: This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Possible That It Carries Out The Mismatch Recognition Step. This Protein Has A Weak Atpase Activity. [C]

COG id: COG1193

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Smr domain [H]

Homologues:

Organism=Escherichia coli, GI1789089, Length=260, Percent_Identity=28.0769230769231, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005747
- InterPro:   IPR000432
- InterPro:   IPR007696
- InterPro:   IPR002625 [H]

Pfam domain/function: PF00488 MutS_V; PF01713 Smr [H]

EC number: NA

Molecular weight: Translated: 87185; Mature: 87054

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50828 SMR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDASKRSLNPTPMNPPMINNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALEND
CCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEHHHH
LKQTFTYLNEVDAIGLPTPKSVKESDLIVIKLTKLGTLHLDEIFEIVKRLRYIVVLQNAF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
KTFTHLKFHERLNAIILPPFFNDLIALLDDEGKIKQGANATLDALNESLNRLKKESAKII
HHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HHYARSKELAPYLVDTQSHLKHGHECLLLKSGFSSAIKGVVLERSANGYFYLLPESAQKI
HHHHHCCCCCCCEECCHHHHCCCCEEEEEECCHHHHHHCCCEEECCCCEEEECCHHHHHH
AQKIAQIGNEIDCCIVEICQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VMPSFTQKKMVLENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSK
ECCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHH
HLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEI
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCE
ELGTDADEASSLYKTLLEKLLKQNNKIVITTHHKRLSVLMAENKEVELLAALYDEEKERP
ECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCC
TYTFLKGVIGKSYAFETALRYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKN
HHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHH
ESLENALKEQEDLKNAWLLEMEKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KIHKASEILNKHKTNQEIPQIITSFQINEKARYKNESVLIAQILDKGYYLVETELGMRLK
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCCCEEEEECCCCEEH
AHGSWLKQIQKPPKNKFKPPKTTIPKPKKASLHLDLRGQRSEEALDLLDAFLNDALLGGF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
EEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SDASKRSLNPTPMNPPMINNNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALEND
CCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEHHHH
LKQTFTYLNEVDAIGLPTPKSVKESDLIVIKLTKLGTLHLDEIFEIVKRLRYIVVLQNAF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
KTFTHLKFHERLNAIILPPFFNDLIALLDDEGKIKQGANATLDALNESLNRLKKESAKII
HHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HHYARSKELAPYLVDTQSHLKHGHECLLLKSGFSSAIKGVVLERSANGYFYLLPESAQKI
HHHHHCCCCCCCEECCHHHHCCCCEEEEEECCHHHHHHCCCEEECCCCEEEECCHHHHHH
AQKIAQIGNEIDCCIVEICQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VMPSFTQKKMVLENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSK
ECCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHH
HLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEI
CCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCE
ELGTDADEASSLYKTLLEKLLKQNNKIVITTHHKRLSVLMAENKEVELLAALYDEEKERP
ECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCC
TYTFLKGVIGKSYAFETALRYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKN
HHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHH
ESLENALKEQEDLKNAWLLEMEKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KIHKASEILNKHKTNQEIPQIITSFQINEKARYKNESVLIAQILDKGYYLVETELGMRLK
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHCCCEEEEECCCCEEH
AHGSWLKQIQKPPKNKFKPPKTTIPKPKKASLHLDLRGQRSEEALDLLDAFLNDALLGGF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
EEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
CCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]