Click here to switch to the map view.

The map label for this gene is glnA [H]

Identifier: 108562911

GI number: 108562911

Start: 503801

End: 505246

Strand: Reverse

Name: glnA [H]

Synonym: HPAG1_0486

Alternate gene names: 108562911

Gene position: 505246-503801 (Counterclockwise)

Preceding gene: 108562918

Following gene: 108562897

Centisome position: 31.65

GC content: 42.39

Gene sequence:

>1446_bases
ATGATAGTAAGAACTCAAAATAGTGAAAGCAAGATCAAAGAGTTTTTTGAATTTTGCAAAGAAAATGAAGTGGAATTTGT
GGATTTTAGATTCAGCGATATTAAAGGCACTTGGAATCACATCGCTTATTCTTTTGGGGCTTTAACGCATGGCATGTTTA
AAGAGGGGATTCCTTTTGATGCGAGTTGTTTTAAAGGCTGGCAAGGCATTGAACACTCCGATATGATTTTAACCCCTGAT
TTGGTGCGTTATTTCATTGATCCTTTTAGCGCGGATGTGAGCGTGGTCGTGTTTTGCGATGTGTATGATGTGTATAAAAA
CCAGCCTTATGAAAAATGCCCTAGAAGTATCGCTAAAAAAGCCTTACAGCATTTAAAAGATTCAGGTTTGGGCGATGTGG
CTTATTTTGGCGCAGAGAATGAATTTTTTATCTTTGATTCCATTAAGATTAAAGACGCTTCCAATTCCCAATACTATGAA
GTGGATAGCGAAGAGGGCGAATGGAATCGGGATAAGAGCTTTGAAAATGGCGTGAATTTTGGGCATAGACCGGGCAAGCA
AGGGGGCTATATGCCTGTGCCGCCAACGGATACGATGATGGATATTCGCACAGAAATCGTGAAAGTCTTAAACCAAGTGG
GGTTAGAAACTTTTGTCGTCCATCATGAAGTCGCGCAAGCGCAAGGCGAAGTGGGAGTGAAATTTGGGGATTTAGTGGAA
GCCGCTGACAATATCCAAAAACTCAAATATGTGGTTAAAATGGTCGCTCATTTAAACGGGAAAACCGCCACTTTCATGCC
AAAACCCCTATATGGGGATAACGGGAGCGGGATGCACACCCATGTGAGTATTTGGAAGAATAACGAAAACCTTTTTAGCG
GCGAAACTTACAAGGGCTTGAGTGAGTTGGCGTTGCATTTTTTAGGGGGCGTGTTGCGCCACGCTAGAGGGTTGGCCGCT
TTCACTAACGCTTCCACTAACTCTTACAAACGCCTGATTCCGGGATATGAAGCCCCATCTATTTTAACTTATTCGGCTAA
TAACAGGAGTGCGAGCGTGCGTATCCCTTATGGGATTTCTAAAAACAGCGCGAGGTTTGAATTCAGGTTTCCTGACAGCT
CATCAAACCCCTACCTGGCTTTTGGGGCTATTTTAATGGCGGGCATGGATGGCGTTAAAAATAAGATCGATCCCGGCGAA
GCGATGGATATTAACCTTTTCAAATTGACTTTAGATGAAATCCGAGAAAAGGGTATCAAACAAATGCCCCACACTTTGAG
GCGATCGTTAGAAGAAATGCTGGCTGATAAGCAGTATTTAAAAGAGGATCAGGTCTTTAGCGAAGAATTTATTCAAACTT
ATCAGTCTCTTAAATTCAACGCTGAAGTGTTCCCATGGGAGAGCAAACCCCATCCTTTTGAATTTATCACCACTTATTCA
TGCTAA

Upstream 100 bases:

>100_bases
GTCTTAATAAAACTTGATACAGATTCTACTTTTTTTACCCCATAAATGCTATAATCACCCCTATCAATCAAACTCAATTC
ATAACAATTAAAGGTGGTTA

Downstream 100 bases:

>100_bases
AACAATGAGTGGGTTAATAATCCCGCTCTAAAAGTTTAGAATAAGGAAAAAATACCTTGTTCTTAAAAAAAGTGGTTGAA
AAAATTTATTTTTTTTTGCT

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDKSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNIQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSIWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFGAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKEDQVFSEEFIQTYQSLKFNAEVFPWESKPHPFEFITTYS
C

Sequences:

>Translated_481_residues
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDKSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNIQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSIWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFGAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKEDQVFSEEFIQTYQSLKFNAEVFPWESKPHPFEFITTYS
C
>Mature_481_residues
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFDASCFKGWQGIEHSDMILTPD
LVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYE
VDSEEGEWNRDKSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
AADNIQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSIWKNNENLFSGETYKGLSELALHFLGGVLRHARGLAA
FTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGISKNSARFEFRFPDSSSNPYLAFGAILMAGMDGVKNKIDPGE
AMDINLFKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKEDQVFSEEFIQTYQSLKFNAEVFPWESKPHPFEFITTYS
C

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1790301, Length=462, Percent_Identity=49.1341991341991, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI87081870, Length=366, Percent_Identity=25.9562841530055, Blast_Score=102, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24641292, Length=332, Percent_Identity=25.6024096385542, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641290, Length=332, Percent_Identity=25.6024096385542, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360453, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17136208, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24580558, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 54558; Mature: 54558

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFD
CEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASCFKGWQGIEHSDMILTPDLVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKK
HHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHH
ALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYEVDSEEGEWNRDKSFENGVNF
HHHHHHHCCCCCEEEECCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHCCCC
GHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHH
AADNIQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSIWKNNENLFSGETYKGL
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHCCH
SELALHFLGGVLRHARGLAAFTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGIS
HHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEECCCCC
KNSARFEFRFPDSSSNPYLAFGAILMAGMDGVKNKIDPGEAMDINLFKLTLDEIREKGIK
CCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHH
QMPHTLRRSLEEMLADKQYLKEDQVFSEEFIQTYQSLKFNAEVFPWESKPHPFEFITTYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECC
C
C
>Mature Secondary Structure
MIVRTQNSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMFKEGIPFD
CEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASCFKGWQGIEHSDMILTPDLVRYFIDPFSADVSVVVFCDVYDVYKNQPYEKCPRSIAKK
HHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHH
ALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNSQYYEVDSEEGEWNRDKSFENGVNF
HHHHHHHCCCCCEEEECCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCHHHCCCC
GHRPGKQGGYMPVPPTDTMMDIRTEIVKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHH
AADNIQKLKYVVKMVAHLNGKTATFMPKPLYGDNGSGMHTHVSIWKNNENLFSGETYKGL
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHCCH
SELALHFLGGVLRHARGLAAFTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIPYGIS
HHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHCCCCCCCCEEEEECCCCCEEEEECCCCC
KNSARFEFRFPDSSSNPYLAFGAILMAGMDGVKNKIDPGEAMDINLFKLTLDEIREKGIK
CCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHH
QMPHTLRRSLEEMLADKQYLKEDQVFSEEFIQTYQSLKFNAEVFPWESKPHPFEFITTYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]