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The map label for this gene is fur [H]

Identifier: 108562845

GI number: 108562845

Start: 428707

End: 429159

Strand: Reverse

Name: fur [H]

Synonym: HPAG1_0420

Alternate gene names: 108562845

Gene position: 429159-428707 (Counterclockwise)

Preceding gene: 108562846

Following gene: 108562839

Centisome position: 26.88

GC content: 37.31

Gene sequence:

>453_bases
ATGAAAAGATTAGAAACTTTGGAATCCATTTTAGAGCGCTTGAGAATGTCTATCAAAAAAAACGGACTCAAAAATTCAAA
ACAAAGAGAAGAAGTGGTGAGCGTTTTGTATCGCAGCGGCACACACTTAAGCCCTGAAGAAATCACGCATTCTATCCGCC
AAAAGGACAAAAACACCAGCATTTCTTCAGTCTATCGCATTTTGAATTTCTTAGAAAAAGAAAATTTTATCTGCGTTTTA
GAAACTTCAAAAAGCGGTCGGCGCTATGAAATTGCGGCTAAAGAACACCATGATCACATCATTTGTTTGCATTGCGGTAA
GATCATTGAATTTGCAGACCCTGAAATTGAAAACCGCCAGAATGAAGTCGTTAAAAAATATCAAGCCAAGCTGATTAGCC
ATGACATGAAAATGTTTGTGTGGTGTAAAGAATGCCAAGAGAGTGAATGTTAA

Upstream 100 bases:

>100_bases
ATTAAAATAATAATGAGTTTTATCTATGTTTCATCGCATTATTATTGTATAATAATATTCTAGTTATAAAAATCATTTTA
CGGATAAGGAAAATACCAGC

Downstream 100 bases:

>100_bases
AAAATTTTAAAGAAGAAGCTTAGATAGGGCTATCTTTAATGGTTTTAAGGACTTCGTCCAGGTTAAAACGCTTGAGTTTT
AGATTTTTGATTTCTTCATC

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVL
ETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIENRQNEVVKKYQAKLISHDMKMFVWCKECQESEC

Sequences:

>Translated_150_residues
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVL
ETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIENRQNEVVKKYQAKLISHDMKMFVWCKECQESEC
>Mature_150_residues
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVL
ETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIENRQNEVVKKYQAKLISHDMKMFVWCKECQESEC

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=136, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17682; Mature: 17682

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ISSVYRILNFLEKENFICVLETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIENRQ
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCEEEEECCCHHHHCCCCCCCHH
NEVVKKYQAKLISHDMKMFVWCKECQESEC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ISSVYRILNFLEKENFICVLETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIENRQ
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCEEEEECCCHHHHCCCCCCCHH
NEVVKKYQAKLISHDMKMFVWCKECQESEC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]