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The map label for this gene is prmA [H]

Identifier: 108562804

GI number: 108562804

Start: 391805

End: 392794

Strand: Reverse

Name: prmA [H]

Synonym: HPAG1_0379

Alternate gene names: 108562804

Gene position: 392794-391805 (Counterclockwise)

Preceding gene: 108562805

Following gene: 108562803

Centisome position: 24.61

GC content: 37.37

Gene sequence:

>990_bases
GTGTTAAAGCCAATGTATTATGAGTTTTTCTTTATCTTCCCTAAGGAGCGAGAGCTTTTTGAGAGCTTTCTTTTAGACAC
CACGCATCTAGCCTTAGAAGAATCAAGCCTAGAAAATTTAAAAGCGTTTGACGATAAAGAAACCATTGAGTTTATAAGCC
AATCCAGTTGGCATTATTTCGCCACTCATGATCCTTTAAAAGAACATTTAAAAGAAAAACCCCAACATCTCAAAAATTTC
GTTATTTTACGCTCTCAAAAGGATTTGAATAACTCGCTCATTCTAGCATTAGAAGCGTTTTGTTTGAATTTAAAACAAAA
CCTGCAAAGTGAGTTTGATTTTTTCTATCTTTCACGCAATTTGGCTTCAAAAGACTGGCTAGAAGCTTACAAACAAGCTA
TTTTGCCGGTGCAATGCGCCAAATTTTACATACACCCTAGTTGGCATCAAAAGCCAAGCCATATCTCTACAGATGATTGC
ATAATGATTGATCCGGCTTTGGCCTTTGGATCAGGCCATCATGAAAGCACTTCTATGTGTTTGGAACTGCTCTCTGACCT
TGATTTAAAACGCAAAAACGCCTTAGATGTGGGCTGTGGGAGCGGGATTTTAAGCATCGCTTTAAAAAAACAAGGCGTTA
GCGCTTTAGTAGCTTGCGATACGGATAGTTTAGCCGTTGAAGAAACCCTAAAAAATTTTAGCTTGAATCAAATACCCCTA
TTAGCGCAAGATAAGGTCATTTATGGCTCTACGCAAAAAATTGAAGGGCGTTTTGATATCATTGTGGCGAACCTTGTCGC
TGATGTGGTTAAGAGTTTGTATAGTGAATTTGTGCGGCTTTGTAACCACACTCTTATTTTGTCAGGGATTTTAGAAACCC
ATTTAAACTCTGTTTTACAGATCTATTATAATGGATTTGAGATTTTAGAACAGCGACAGCGTAACGAATGGGTCGCTCTA
AAATTGCTTAAAAAACAACCAATAAATTAA

Upstream 100 bases:

>100_bases
TACGGCTTTGAAAGCGGGCGTGAATAACTACATTGTGAAACCTTTTACCCCCCAGGTTTTGAAAGAAAAATTAGAGGTTG
TTTTAGGGACAAACGATTGA

Downstream 100 bases:

>100_bases
GGATTATAATGAAACCAACGAACGAACCTAAAAAACCTTTTTTTCAAAGTCCCATTATCCTTGCGGTTCTTGGAGGGATT
TTACTCATTTTTTTTCTGCG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLKPMYYEFFFIFPKERELFESFLLDTTHLALEESSLENLKAFDDKETIEFISQSSWHYFATHDPLKEHLKEKPQHLKNF
VILRSQKDLNNSLILALEAFCLNLKQNLQSEFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHISTDDC
IMIDPALAFGSGHHESTSMCLELLSDLDLKRKNALDVGCGSGILSIALKKQGVSALVACDTDSLAVEETLKNFSLNQIPL
LAQDKVIYGSTQKIEGRFDIIVANLVADVVKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEILEQRQRNEWVAL
KLLKKQPIN

Sequences:

>Translated_329_residues
MLKPMYYEFFFIFPKERELFESFLLDTTHLALEESSLENLKAFDDKETIEFISQSSWHYFATHDPLKEHLKEKPQHLKNF
VILRSQKDLNNSLILALEAFCLNLKQNLQSEFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHISTDDC
IMIDPALAFGSGHHESTSMCLELLSDLDLKRKNALDVGCGSGILSIALKKQGVSALVACDTDSLAVEETLKNFSLNQIPL
LAQDKVIYGSTQKIEGRFDIIVANLVADVVKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEILEQRQRNEWVAL
KLLKKQPIN
>Mature_329_residues
MLKPMYYEFFFIFPKERELFESFLLDTTHLALEESSLENLKAFDDKETIEFISQSSWHYFATHDPLKEHLKEKPQHLKNF
VILRSQKDLNNSLILALEAFCLNLKQNLQSEFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHISTDDC
IMIDPALAFGSGHHESTSMCLELLSDLDLKRKNALDVGCGSGILSIALKKQGVSALVACDTDSLAVEETLKNFSLNQIPL
LAQDKVIYGSTQKIEGRFDIIVANLVADVVKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEILEQRQRNEWVAL
KLLKKQPIN

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=209, Percent_Identity=32.5358851674641, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 37780; Mature: 37780

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPMYYEFFFIFPKERELFESFLLDTTHLALEESSLENLKAFDDKETIEFISQSSWHYF
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
ATHDPLKEHLKEKPQHLKNFVILRSQKDLNNSLILALEAFCLNLKQNLQSEFDFFYLSRN
ECCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHH
LASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHISTDDCIMIDPALAFGSGHHESTSMC
CCCHHHHHHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCEEEECCHHHCCCCCCHHHHHH
LELLSDLDLKRKNALDVGCGSGILSIALKKQGVSALVACDTDSLAVEETLKNFSLNQIPL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCE
LAQDKVIYGSTQKIEGRFDIIVANLVADVVKSLYSEFVRLCNHTLILSGILETHLNSVLQ
EECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYYNGFEILEQRQRNEWVALKLLKKQPIN
HHHHHHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MLKPMYYEFFFIFPKERELFESFLLDTTHLALEESSLENLKAFDDKETIEFISQSSWHYF
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
ATHDPLKEHLKEKPQHLKNFVILRSQKDLNNSLILALEAFCLNLKQNLQSEFDFFYLSRN
ECCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHH
LASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHISTDDCIMIDPALAFGSGHHESTSMC
CCCHHHHHHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCEEEECCHHHCCCCCCHHHHHH
LELLSDLDLKRKNALDVGCGSGILSIALKKQGVSALVACDTDSLAVEETLKNFSLNQIPL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCE
LAQDKVIYGSTQKIEGRFDIIVANLVADVVKSLYSEFVRLCNHTLILSGILETHLNSVLQ
EECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYYNGFEILEQRQRNEWVALKLLKKQPIN
HHHHHHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9244252; 9252185 [H]