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The map label for this gene is hflC [C]

Identifier: 108562676

GI number: 108562676

Start: 254566

End: 255654

Strand: Direct

Name: hflC [C]

Synonym: HPAG1_0251

Alternate gene names: 108562676

Gene position: 254566-255654 (Clockwise)

Preceding gene: 108562675

Following gene: 108562677

Centisome position: 15.95

GC content: 44.17

Gene sequence:

>1089_bases
ATGCCCATTGATTTGAACGAACATTTAAAAAAGAAAAATTCTCAAAGAGAAACCCCCACGCCTAATACGCCTAATAATGG
GGGGCGTTTCATCCCGCCGTCTAACTCTTTTAATTCTAAAAAACTATCGGTTTTGATTGTCATTGTCCTTTTAGGCGTTA
TCGCTTTTTTGGCCAAGCCTTTTGAAGTGATCAGCTCAGGAGAAATTGGCATTAAAATCACCGCCGGGAAATACGAACCC
ACCCCCTTACAGCCAGGAATCCACTTTTTTGTGCCTATCATTCAAGACATTCTCATTGTAGATACAAGGATCAGGAATAT
CAATTTTTCACGCACCGAAGACATGGGCGTGGCGGGTAAAAACCAAGGGATTTTTAGAAACGACGCTATTAATGTGATGG
ATAGCAGGGGTTTGACCGTTTCTATTGAACTCACCGTGCAATACCGCCTAAACCCCCAAACCACCCCCCAAACGATCGCT
ACTTATGGCTTGTCTTGGGAGCAAAAAATCATCAACCCTGTGGTGCGCGATGTGGTGCGATCTGTGGTGGGGCGCTATCC
GGCTGAAGATTTACCCATTAAGCGCAATGAAATCGCCGCTCTTATTAATAGCGGTATCAATAAAGAAGTTTCTAAGCTCC
CCAACACCCCTGTGGAATTAAGCTCTATCCAATTGAGAGAAATCGTCTTGCCCGCTAAGATTAAAGAGCAAATTGAAAAA
GTCCAAATCGCGCGCCAAGAATCAGAAAGGGTGAAATACGAGGTGGAGCGCTCCAAACAAGAAGCTCAAAAACAAGCCGC
TTTGGCTAAAGGGGAAGCGGACGCTAACAGGATTAAGGCTCAGGGCGTGGCTGATGCGATAGTGATTGAGGCTAAGGCAA
AATCTCAAGCCAATTTAAGCATTTCACAAAGCCTGAGCGACAAGCTTTTAAGGCTGCGCCAAATTGAAGTTCAAGGTCAG
TTTAATGAAGCGTTAAAAACGAATAATAACGCTCAAATCATGCTCACTCCAGGCGGGGCTGTGCCTAATATTTGGATTGA
CACTAAAAGTAAGGTTAAATCTAGTATCGCTGAGACTAAAGAGCCTTAA

Upstream 100 bases:

>100_bases
CGCGTTCTTTCAAAAAGGGCCAGCACAGAGACAGACACCCTAAAACAAACCACCATTCTAAAAAACCCAAACGCCGTTAA
AATATTTAAAAAGGAAATTC

Downstream 100 bases:

>100_bases
AAACGCATGGCGTCTCTTGCCTTTATCCAAGCTTTTTTGGAGTCTTTTAAGGGCTTTTTAAATCAAGCGACTTTAATTAG
CGTTTTAATAGCGAGCGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: SPFH Domain-Containing Protein; SPFH Domain-Containing Protein/Band 7 Family Protein; Band 7 Family Protein; Spfh Domain Band 7 Family Protein; Cation-Transporting ATPase/ Band 7 Family Protein; B-Cell Receptor Associated Protein-Related Protein; Spfh Domain Protein; Cation-Transporting ATPase P-Type; SPFH Domain Band 7 Family Protein

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPIDLNEHLKKKNSQRETPTPNTPNNGGRFIPPSNSFNSKKLSVLIVIVLLGVIAFLAKPFEVISSGEIGIKITAGKYEP
TPLQPGIHFFVPIIQDILIVDTRIRNINFSRTEDMGVAGKNQGIFRNDAINVMDSRGLTVSIELTVQYRLNPQTTPQTIA
TYGLSWEQKIINPVVRDVVRSVVGRYPAEDLPIKRNEIAALINSGINKEVSKLPNTPVELSSIQLREIVLPAKIKEQIEK
VQIARQESERVKYEVERSKQEAQKQAALAKGEADANRIKAQGVADAIVIEAKAKSQANLSISQSLSDKLLRLRQIEVQGQ
FNEALKTNNNAQIMLTPGGAVPNIWIDTKSKVKSSIAETKEP

Sequences:

>Translated_362_residues
MPIDLNEHLKKKNSQRETPTPNTPNNGGRFIPPSNSFNSKKLSVLIVIVLLGVIAFLAKPFEVISSGEIGIKITAGKYEP
TPLQPGIHFFVPIIQDILIVDTRIRNINFSRTEDMGVAGKNQGIFRNDAINVMDSRGLTVSIELTVQYRLNPQTTPQTIA
TYGLSWEQKIINPVVRDVVRSVVGRYPAEDLPIKRNEIAALINSGINKEVSKLPNTPVELSSIQLREIVLPAKIKEQIEK
VQIARQESERVKYEVERSKQEAQKQAALAKGEADANRIKAQGVADAIVIEAKAKSQANLSISQSLSDKLLRLRQIEVQGQ
FNEALKTNNNAQIMLTPGGAVPNIWIDTKSKVKSSIAETKEP
>Mature_361_residues
PIDLNEHLKKKNSQRETPTPNTPNNGGRFIPPSNSFNSKKLSVLIVIVLLGVIAFLAKPFEVISSGEIGIKITAGKYEPT
PLQPGIHFFVPIIQDILIVDTRIRNINFSRTEDMGVAGKNQGIFRNDAINVMDSRGLTVSIELTVQYRLNPQTTPQTIAT
YGLSWEQKIINPVVRDVVRSVVGRYPAEDLPIKRNEIAALINSGINKEVSKLPNTPVELSSIQLREIVLPAKIKEQIEKV
QIARQESERVKYEVERSKQEAQKQAALAKGEADANRIKAQGVADAIVIEAKAKSQANLSISQSLSDKLLRLRQIEVQGQF
NEALKTNNNAQIMLTPGGAVPNIWIDTKSKVKSSIAETKEP

Specific function: Hflc And Hflk Govern The Stability Of Phage Lambda Cii Protein And Have Been Proposed To Encode Or Regulate A Cii- Specific Protease. [C]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6005854, Length=213, Percent_Identity=24.8826291079812, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221307584, Length=213, Percent_Identity=24.8826291079812, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193205005, Length=199, Percent_Identity=24.6231155778894, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321571, Length=246, Percent_Identity=23.1707317073171, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40006; Mature: 39874

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDLNEHLKKKNSQRETPTPNTPNNGGRFIPPSNSFNSKKLSVLIVIVLLGVIAFLAKP
CCCCHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
FEVISSGEIGIKITAGKYEPTPLQPGIHFFVPIIQDILIVDTRIRNINFSRTEDMGVAGK
HHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NQGIFRNDAINVMDSRGLTVSIELTVQYRLNPQTTPQTIATYGLSWEQKIINPVVRDVVR
CCCCCCCCCCCEEECCCCEEEEEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
SVVGRYPAEDLPIKRNEIAALINSGINKEVSKLPNTPVELSSIQLREIVLPAKIKEQIEK
HHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEHHHHHCCHHHHHHHHH
VQIARQESERVKYEVERSKQEAQKQAALAKGEADANRIKAQGVADAIVIEAKAKSQANLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCH
ISQSLSDKLLRLRQIEVQGQFNEALKTNNNAQIMLTPGGAVPNIWIDTKSKVKSSIAETK
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHCC
EP
CC
>Mature Secondary Structure 
PIDLNEHLKKKNSQRETPTPNTPNNGGRFIPPSNSFNSKKLSVLIVIVLLGVIAFLAKP
CCCHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
FEVISSGEIGIKITAGKYEPTPLQPGIHFFVPIIQDILIVDTRIRNINFSRTEDMGVAGK
HHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
NQGIFRNDAINVMDSRGLTVSIELTVQYRLNPQTTPQTIATYGLSWEQKIINPVVRDVVR
CCCCCCCCCCCEEECCCCEEEEEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
SVVGRYPAEDLPIKRNEIAALINSGINKEVSKLPNTPVELSSIQLREIVLPAKIKEQIEK
HHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEHHHHHCCHHHHHHHHH
VQIARQESERVKYEVERSKQEAQKQAALAKGEADANRIKAQGVADAIVIEAKAKSQANLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCH
ISQSLSDKLLRLRQIEVQGQFNEALKTNNNAQIMLTPGGAVPNIWIDTKSKVKSSIAETK
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHCC
EP
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA