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The map label for this gene is dapE [H]

Identifier: 108562638

GI number: 108562638

Start: 216501

End: 217652

Strand: Reverse

Name: dapE [H]

Synonym: HPAG1_0213

Alternate gene names: 108562638

Gene position: 217652-216501 (Counterclockwise)

Preceding gene: 108562639

Following gene: 108562637

Centisome position: 13.63

GC content: 40.89

Gene sequence:

>1152_bases
ATGGACGCTTTAGAAATCACCCAAAAGCTCATCAGCTACCCCACCATTACGCCCAAAGAATGCGGTATTTTTGAATACAT
TAAATCGCTTTTTCCTCATTTTAAAACTCTAGAGTGTGGAGAAAATGGCGTGAAAAACCTTTTTTTATACCGCATTTTTA
ACCCCCCCAAAGACCATGCAGAAGAAAAGCATGCAAAAGAAAATGTTAAGCCCTTGCATTTTTCTTTTGCAGGGCATATT
GATGTCGTGCCTCCTGGAGATCATTGGCAAAACGATCCTTTTAAACCCGTTATTAAAGAGGGGTTTTTATACGGCCGTGG
GGCGCAAGACATGAAAGGAGGCGTGGGGGCGTTTTTGAGCGCGAGTTTAAATTTTAACCCTAAAACCCCTTTTTTGCTTT
CTATTTTACTCACAAGCGATGAAGAAGGGCCAGGGATTTTTGGCACAAAACTCATGTTAGAAAAGCTCAAAGAAAAAGAT
TTGTTGCCTCATATGGCGATTGTGGCTGAACCCACTTGCGAAAAAGTCCTAGGCGATAGCATCAAAATTGGCCGAAGAGG
CTCTATTAATGGCAAACTCATTTTAAAAGGCATTCAAGGGCATGCGGCTTACCCAAAAAAATGCCAAAACCCCATTGATA
CGCTCGCTTCTGTTTTGCCCTTGATTTCAGGAGTTAATTTAGACGATGGCGATGAATATTTTGACCCTTCAAAATTGGTT
ATCACCAACTTGCATGCAGGGTTAGGAGCGAATAACGTTACCCCGGCAAGCGTAGAAATCATCTTTAATGCACGCCATTC
TTTAAAAACCACCAAAGAGAGTTTGAAAGAATATTTAGAAAAAGTTTTAAAAGATTTGCCTCACACTTTAGAATTAGAGT
CAAGCAGTTCGCCTTTCATCACGGCTTCTCATTCAAAGCTTACCAGCGTTTTAAAAGAAAATATTTTAAAGACATGCCGC
ACCACCCCCCTTTTAAACACCAAAGGCGGCACGAGCGATGCGCGATTTTTTAGCGCTCATGGTATAGAAGTGGTGGAATT
TGGCGTTATTAATGACAGGATTCATGCCATTGATGAAAGGGTGAGCTTGAAAGAATTAGAGCTTTTAGAAAAAGTGTTTT
TGGGGGTTTTAGAGGATTTGAGCGAGAAATGA

Upstream 100 bases:

>100_bases
AAGCCTTTTTGAAGCCTCAGAAATCAGCGGGATCACCCCAGCGAATTTAGACGTTTTGCATTTGTATATTCATTTGCGGA
AAAACTCTTAAAGGATTGGC

Downstream 100 bases:

>100_bases
ATGTGGAGTTTTGGCGTAAGGGTTTTATTTTTAATACCAACGCCTTTTTCGCTGGCAAAAACCACCAAACCAACTCAAGC
TTTAGCATGTGCTAGTATCC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHAEEKHAKENVKPLHFSFAGHI
DVVPPGDHWQNDPFKPVIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTKLMLEKLKEKD
LLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGIQGHAAYPKKCQNPIDTLASVLPLISGVNLDDGDEYFDPSKLV
ITNLHAGLGANNVTPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPHTLELESSSSPFITASHSKLTSVLKENILKTCR
TTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDERVSLKELELLEKVFLGVLEDLSEK

Sequences:

>Translated_383_residues
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHAEEKHAKENVKPLHFSFAGHI
DVVPPGDHWQNDPFKPVIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTKLMLEKLKEKD
LLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGIQGHAAYPKKCQNPIDTLASVLPLISGVNLDDGDEYFDPSKLV
ITNLHAGLGANNVTPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPHTLELESSSSPFITASHSKLTSVLKENILKTCR
TTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDERVSLKELELLEKVFLGVLEDLSEK
>Mature_383_residues
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHAEEKHAKENVKPLHFSFAGHI
DVVPPGDHWQNDPFKPVIKEGFLYGRGAQDMKGGVGAFLSASLNFNPKTPFLLSILLTSDEEGPGIFGTKLMLEKLKEKD
LLPHMAIVAEPTCEKVLGDSIKIGRRGSINGKLILKGIQGHAAYPKKCQNPIDTLASVLPLISGVNLDDGDEYFDPSKLV
ITNLHAGLGANNVTPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPHTLELESSSSPFITASHSKLTSVLKENILKTCR
TTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDERVSLKELELLEKVFLGVLEDLSEK

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=388, Percent_Identity=34.5360824742268, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 42306; Mature: 42306

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEHHCCCCCCCEEEEEEECCCCHHHH
EEKHAKENVKPLHFSFAGHIDVVPPGDHWQNDPFKPVIKEGFLYGRGAQDMKGGVGAFLS
HHHHHHHCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHCCCEECCCCHHHCCCCCHHEE
ASLNFNPKTPFLLSILLTSDEEGPGIFGTKLMLEKLKEKDLLPHMAIVAEPTCEKVLGDS
EECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHEECCHHHHHCCCC
IKIGRRGSINGKLILKGIQGHAAYPKKCQNPIDTLASVLPLISGVNLDDGDEYFDPSKLV
CCCCCCCCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ITNLHAGLGANNVTPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPHTLELESSSSPFI
EEEHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
TASHSKLTSVLKENILKTCRTTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDER
EECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHHHH
VSLKELELLEKVFLGVLEDLSEK
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDALEITQKLISYPTITPKECGIFEYIKSLFPHFKTLECGENGVKNLFLYRIFNPPKDHA
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEHHCCCCCCCEEEEEEECCCCHHHH
EEKHAKENVKPLHFSFAGHIDVVPPGDHWQNDPFKPVIKEGFLYGRGAQDMKGGVGAFLS
HHHHHHHCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHCCCEECCCCHHHCCCCCHHEE
ASLNFNPKTPFLLSILLTSDEEGPGIFGTKLMLEKLKEKDLLPHMAIVAEPTCEKVLGDS
EECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHEECCHHHHHCCCC
IKIGRRGSINGKLILKGIQGHAAYPKKCQNPIDTLASVLPLISGVNLDDGDEYFDPSKLV
CCCCCCCCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
ITNLHAGLGANNVTPASVEIIFNARHSLKTTKESLKEYLEKVLKDLPHTLELESSSSPFI
EEEHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEE
TASHSKLTSVLKENILKTCRTTPLLNTKGGTSDARFFSAHGIEVVEFGVINDRIHAIDER
EECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHHHH
VSLKELELLEKVFLGVLEDLSEK
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA