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The map label for this gene is hcpA [H]

Identifier: 108562637

GI number: 108562637

Start: 215289

End: 216041

Strand: Reverse

Name: hcpA [H]

Synonym: HPAG1_0212

Alternate gene names: 108562637

Gene position: 216041-215289 (Counterclockwise)

Preceding gene: 108562638

Following gene: 108562634

Centisome position: 13.53

GC content: 40.9

Gene sequence:

>753_bases
ATGCTAGGAAGCGTTAAAAAAACCCTTTTTGGGGTCTTGTGTTTGGGCGCGTTGTGTTTGAGAGGGTTAATGGCAGAGCC
AGACGCTAAAGAGCTTGTTAATTTAGGCATAGAGAGCGCAAAGAAGCAAGATTTCGCTCAAGCTAAAACGCATTTTGAAA
AAGCTTGTGAGTTAAAAAATGGCTTTGGGTGTGTTTTTTTAGGGGCGTTCTATGAAGAAGGGAAAGGAGTGGGAAAAGAC
TTGAAAAAAGCCATCCAATTTTACACTAAAGGTTGTGAATTAAATGATGGTTATGGGTGCAACCTGCTAGGCAATTTATA
CTATAACGGACAAGGCGTGTCAAAAGACGCTAAAAAAGCCTCACAATACTACTCTAAAGCTTGCGACTTAAACCATGCTG
AAGGGTGTATGGTATTAGGAAGCTTACACCATTATGGCGTAGGCACGCCTAAGGATTTAAGAAAGGCTCTTGATTTGTAT
GAAAAGGCTTGCGATTTAAAAGACAGCCCCGGGTGCATTAATGCAGGATACATGTATGGTGCAGCAAAGAATTTTAAGGA
GGCTATCGTTCGTTATTCTCAAGCTTGCGAGTTAAAAGATGGCAGGGGGTGTTATAATTTAGGGGTTATGCAATACAACG
CCCAAGGCACAGCAAAGGACGAAAAGCAAGCGGTAGAAAACTTTAAAAAAGGTTGCAAATCAAGCGTTAAAGAAGCATGC
GACGCTCTCAAGGAATTAAAAATAGAACTTTAA

Upstream 100 bases:

>100_bases
TTTTTTCTTTATTCTATCAATAAAGGTTCAATAAGGATTCAATCGTCAATATTTGATTATAATTGTAAAGGATTACATTT
TTTATAATAGGAGATATACC

Downstream 100 bases:

>100_bases
TTTTAATGAAGTTAAGCTAAACGCCGCGTTTAGCTGGCTTTTACGCTTTTTAATCTTTTAAGGAAAACATAAACCCTACA
GAATAATCATTTTTAATGAT

Product: cysteine-rich protein A

Products: NA

Alternate protein names: Cysteine-rich 28 kDa protein [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFAQAKTHFEKACELKNGFGCVFLGAFYEEGKGVGKD
LKKAIQFYTKGCELNDGYGCNLLGNLYYNGQGVSKDAKKASQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLY
EKACDLKDSPGCINAGYMYGAAKNFKEAIVRYSQACELKDGRGCYNLGVMQYNAQGTAKDEKQAVENFKKGCKSSVKEAC
DALKELKIEL

Sequences:

>Translated_250_residues
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFAQAKTHFEKACELKNGFGCVFLGAFYEEGKGVGKD
LKKAIQFYTKGCELNDGYGCNLLGNLYYNGQGVSKDAKKASQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLY
EKACDLKDSPGCINAGYMYGAAKNFKEAIVRYSQACELKDGRGCYNLGVMQYNAQGTAKDEKQAVENFKKGCKSSVKEAC
DALKELKIEL
>Mature_250_residues
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFAQAKTHFEKACELKNGFGCVFLGAFYEEGKGVGKD
LKKAIQFYTKGCELNDGYGCNLLGNLYYNGQGVSKDAKKASQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLY
EKACDLKDSPGCINAGYMYGAAKNFKEAIVRYSQACELKDGRGCYNLGVMQYNAQGTAKDEKQAVENFKKGCKSSVKEAC
DALKELKIEL

Specific function: Slowly hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. May be involved in the synthesis of the cell wall peptidoglycan [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI87081769, Length=241, Percent_Identity=23.2365145228216, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355295, Length=165, Percent_Identity=30.9090909090909, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 27239; Mature: 27239

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFAQAKTHFEKACELKN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GFGCVFLGAFYEEGKGVGKDLKKAIQFYTKGCELNDGYGCNLLGNLYYNGQGVSKDAKKA
CCCCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECEEECCCCCCHHHHHH
SQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLYEKACDLKDSPGCINAGYMYG
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AAKNFKEAIVRYSQACELKDGRGCYNLGVMQYNAQGTAKDEKQAVENFKKGCKSSVKEAC
HHHHHHHHHHHHHHHHCCCCCCCEEEECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
DALKELKIEL
HHHHHHHCCC
>Mature Secondary Structure
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFAQAKTHFEKACELKN
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GFGCVFLGAFYEEGKGVGKDLKKAIQFYTKGCELNDGYGCNLLGNLYYNGQGVSKDAKKA
CCCCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECEEECCCCCCHHHHHH
SQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLYEKACDLKDSPGCINAGYMYG
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AAKNFKEAIVRYSQACELKDGRGCYNLGVMQYNAQGTAKDEKQAVENFKKGCKSSVKEAC
HHHHHHHHHHHHHHHHCCCCCCCEEEECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
DALKELKIEL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]