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The map label for this gene is mcp4 [H]

Identifier: 108562524

GI number: 108562524

Start: 101761

End: 103788

Strand: Direct

Name: mcp4 [H]

Synonym: HPAG1_0099

Alternate gene names: 108562524

Gene position: 101761-103788 (Clockwise)

Preceding gene: 108562521

Following gene: 108562525

Centisome position: 6.37

GC content: 39.79

Gene sequence:

>2028_bases
TTGTCTAAAGGTTTGAGTATCGGTAATAAAATCATATTGTGCGTGGCGTTGATTGTGATCGTGTGCGTGAGCATTTTAGG
GGTGTCCTTAAACAGCAGGGTGAAAGAGATTTTAAAAGAAAGCGCTTTGCATTCTATGCAAGATAGTTTGCATTTTAAGG
TTAAGGAAGTGCAAGGGGTTTTGGAAAACACCTATACGAGCATGGGCATTGTCAAAGAAATGCTCCCTAAAGACATCAAA
AGAGAAATCAAAATCCACTTGTTAAAAAACTTCATTTTAGCCAATTCGCATGTCGCTGGGGTGAGCATGTTTTTTAAAGG
CAGAGAAGATTTAAGATTAACGCTTTTAAGGGATAACAATACGATTAAGCTAGTGGAAAATCCGTCATTAGAGAATAGCC
CTTTAGCGCAAAAAGCGATGAAAAATAAAGAAATTTCTAAAAGCCTGCCTTATTATAGGAAAATGCCTAATGGGGCGGAA
GTTTATGGGGTTGATATTCTTTTACCTTTATTGAATGAAAACGCTCAAGAGGTTGTAGGGGCTTTGATGGTTTTTATTTC
CATTGACAGCTTCAGCAATGAAATCACTAAAAACAGGAGCGATTTATTTTTAATTGGCGTTAAAGGTAAAGTGCTTTTGA
GCGCGAATAAGAGTTTGCAAGACAAACCTATCGCAGAAATTTATAAGAGCGTGCCTAAAGCCACCAGCGAAGTGCTAACT
ATTTTAGAAAACGGCTCTAAAGCGACTTTAGAATACCTGGATCCCTTTAGCCATAAGGAAAATTTTTTAGCCGTTGAAAC
CTTTAAAATGCTAGGCAAAACAGAAAGTAAAGACAATCTTAATTGGATGATCGCTTTAATCATTGAAAAAGACAAGGTCT
ATGAGCAAGTAGGATCGGTGCGTTTTGTGGTGATCATAGCGAGCGCGATCATGGTGTTAGCCTTGATTATAGCGATCACT
CTCTTAATGCGAGCGATCGTGAGCAATCGTTTGGAAATCGTTTCTAGCACCTTGTCTCACTTCTTTAAGTTATTGAACAA
TCAAGCCCATTCCAGCGGTATTAAATTGATTGAAGCGAAATCTAATGACGAATTAGGGCGCATGCAAACAGCGATCAATA
AAAATATCTTGCAAACCCAAAAAACCATGCAAGAAGACAGGCAAGCCGTCCAAGACACCATTAAAGTGGTTTCAGACGTG
AAAGCAGGGAATTTTGCGGTGCGCATCACGGCTGAGCCTGCAAGCCCTGATTTGAAAGAATTGAGAGACGCGCTAAACGG
GATCATGGATTATTTGCAAGAAAGCGTAGGGACTCACATGCCAAGCATTTTCAAAATCTTTGAAAGCTATTCTGGTTTGG
ACTTTAGAGGGCGGATCCAAAACGCTTCGGGTAGGGTGGAATTGGTTACTAACGCTTTAGGGCAAGAAATCCAAAAAATG
CTAGAAACTTCGTCTAATTTTGCCAAAGATTTAGCGAACGATAGTGCGAATTTAAAAGAATGCGTGCAAAATTTAGAAAA
GGCTTCAAACTCCCAACACAAAAGCTTGATGGAAACTTCTAAAACGATAGAAAATATCACCACTTCCATTCAAGGCGTGA
GCTCTCAAAGTGAAGCCATGATTGAACAAGGGCAAGACATTAAAAGCATTGTAGAAATCATCAGAGACATCGCTGATCAA
ACCAATCTTTTAGCCCTGAATGCTGCTATTGAAGCCGCAAGAGCCGGCGAGCATGGCAGAGGCTTTGCGGTGGTGGCTGA
TGAGGTGAGAAAGCTCGCTGAAAGGACGCAAAAATCGCTCAGCGAAATTGAAGCCAATATTAATATTCTCGTTCAAAGCA
TTTCAGACACGAGCGAAAGCATTAAAAACCAGGTTAAGGAAGTGGAAGAAATCAACGCTTCTATTGAAGCCTTAAGATCG
GTTACTGAGGGCAATCTAAAAATCGCTAGCGATTCTTTAGAAATCAGTCAAGAAATTGACAAAGTCTCTAACGATATTTT
AGAAGACGTGAATAAAAAGCAGTTTTAA

Upstream 100 bases:

>100_bases
TTAATCCAGTTTAATTTTTGATTTATGCCTATAATACTATAATGCGGTTTAAAAATTTGCCGCAAATGGGCAAAAAATTT
CATCATAGTAAGGTTGTGTT

Downstream 100 bases:

>100_bases
TGCTCATTCATATTTGTTGCTCAGTGGATAATCTGTATTTTTTAAAAAAAGCTAAAGAGGCTTTTGCGGGTGAAAAAATT
GTAGGGTTTTTTTATAACCC

Product: methyl-accepting chemotaxis transmembrane sensory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MSKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKESALHSMQDSLHFKVKEVQGVLENTYTSMGIVKEMLPKDIK
REIKIHLLKNFILANSHVAGVSMFFKGREDLRLTLLRDNNTIKLVENPSLENSPLAQKAMKNKEISKSLPYYRKMPNGAE
VYGVDILLPLLNENAQEVVGALMVFISIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKPIAEIYKSVPKATSEVLT
ILENGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIALIIEKDKVYEQVGSVRFVVIIASAIMVLALIIAIT
LLMRAIVSNRLEIVSSTLSHFFKLLNNQAHSSGIKLIEAKSNDELGRMQTAINKNILQTQKTMQEDRQAVQDTIKVVSDV
KAGNFAVRITAEPASPDLKELRDALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEIQKM
LETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAMIEQGQDIKSIVEIIRDIADQ
TNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRS
VTEGNLKIASDSLEISQEIDKVSNDILEDVNKKQF

Sequences:

>Translated_675_residues
MSKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKESALHSMQDSLHFKVKEVQGVLENTYTSMGIVKEMLPKDIK
REIKIHLLKNFILANSHVAGVSMFFKGREDLRLTLLRDNNTIKLVENPSLENSPLAQKAMKNKEISKSLPYYRKMPNGAE
VYGVDILLPLLNENAQEVVGALMVFISIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKPIAEIYKSVPKATSEVLT
ILENGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIALIIEKDKVYEQVGSVRFVVIIASAIMVLALIIAIT
LLMRAIVSNRLEIVSSTLSHFFKLLNNQAHSSGIKLIEAKSNDELGRMQTAINKNILQTQKTMQEDRQAVQDTIKVVSDV
KAGNFAVRITAEPASPDLKELRDALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEIQKM
LETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAMIEQGQDIKSIVEIIRDIADQ
TNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRS
VTEGNLKIASDSLEISQEIDKVSNDILEDVNKKQF
>Mature_674_residues
SKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKESALHSMQDSLHFKVKEVQGVLENTYTSMGIVKEMLPKDIKR
EIKIHLLKNFILANSHVAGVSMFFKGREDLRLTLLRDNNTIKLVENPSLENSPLAQKAMKNKEISKSLPYYRKMPNGAEV
YGVDILLPLLNENAQEVVGALMVFISIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKPIAEIYKSVPKATSEVLTI
LENGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIALIIEKDKVYEQVGSVRFVVIIASAIMVLALIIAITL
LMRAIVSNRLEIVSSTLSHFFKLLNNQAHSSGIKLIEAKSNDELGRMQTAINKNILQTQKTMQEDRQAVQDTIKVVSDVK
AGNFAVRITAEPASPDLKELRDALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEIQKML
ETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAMIEQGQDIKSIVEIIRDIADQT
NLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRSV
TEGNLKIASDSLEISQEIDKVSNDILEDVNKKQF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=206, Percent_Identity=34.9514563106796, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1787690, Length=165, Percent_Identity=40.6060606060606, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788195, Length=179, Percent_Identity=36.8715083798883, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789453, Length=199, Percent_Identity=31.6582914572864, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788194, Length=187, Percent_Identity=34.7593582887701, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74662; Mature: 74531

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKESALHSMQDSLHFKVKEVQGV
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENTYTSMGIVKEMLPKDIKREIKIHLLKNFILANSHVAGVSMFFKGREDLRLTLLRDNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCC
TIKLVENPSLENSPLAQKAMKNKEISKSLPYYRKMPNGAEVYGVDILLPLLNENAQEVVG
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCEEHHHHHHHHHCCCHHHHHH
ALMVFISIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKPIAEIYKSVPKATSEVLT
HHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCCCHHHHHHHHCHHHHHHHH
ILENGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIALIIEKDKVYEQVGSV
HHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHCCH
RFVVIIASAIMVLALIIAITLLMRAIVSNRLEIVSSTLSHFFKLLNNQAHSSGIKLIEAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
SNDELGRMQTAINKNILQTQKTMQEDRQAVQDTIKVVSDVKAGNFAVRITAEPASPDLKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
LRDALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEIQKM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAM
HHCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IEQGQDIKSIVEIIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSL
HHCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRSVTEGNLKIASDSLEISQEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHH
KVSNDILEDVNKKQF
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKESALHSMQDSLHFKVKEVQGV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENTYTSMGIVKEMLPKDIKREIKIHLLKNFILANSHVAGVSMFFKGREDLRLTLLRDNN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEEECCC
TIKLVENPSLENSPLAQKAMKNKEISKSLPYYRKMPNGAEVYGVDILLPLLNENAQEVVG
EEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCEEHHHHHHHHHCCCHHHHHH
ALMVFISIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKPIAEIYKSVPKATSEVLT
HHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCCCHHHHHHHHCHHHHHHHH
ILENGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIALIIEKDKVYEQVGSV
HHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHCCH
RFVVIIASAIMVLALIIAITLLMRAIVSNRLEIVSSTLSHFFKLLNNQAHSSGIKLIEAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
SNDELGRMQTAINKNILQTQKTMQEDRQAVQDTIKVVSDVKAGNFAVRITAEPASPDLKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
LRDALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEIQKM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAM
HHCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IEQGQDIKSIVEIIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSL
HHCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
SEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRSVTEGNLKIASDSLEISQEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHH
KVSNDILEDVNKKQF
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]