Click here to switch to the map view.

The map label for this gene is mqo [H]

Identifier: 108562512

GI number: 108562512

Start: 87598

End: 88950

Strand: Reverse

Name: mqo [H]

Synonym: HPAG1_0087

Alternate gene names: 108562512

Gene position: 88950-87598 (Counterclockwise)

Preceding gene: 108562513

Following gene: 108562511

Centisome position: 5.57

GC content: 41.02

Gene sequence:

>1353_bases
ATGAGTATGGAATTTGATGCTGTTATTATTGGAGGTGGGGTTTCAGGGTGCGCGACCTTTTATACTTTGAGCGAATACAG
CTCCTTAAAGCGCGTGGCTATCGTGGAAAAATGCTCTAAATTGGCTCAAATCAGCTCCAGCGCTAAAGCTAATTCGCAAA
CCATTCATGATGGCTCTATTGAAACAAATTACACTCCCGAAAAAGCTAAAAAAGTGCGTTTGAGCGCTTATAAGACCAGA
CAATACGCGCTCAATAAAGGCTTGCAAAATGAAGTGATTTTTGAAACCCAGAAAATGGCTATAGGCGTGGGCGATGAAGA
ATGCGAGTTCATGAAAAAACGCTATGAATCCTTTAAAGAAATCTTTGTGGGGCTAGAAGAATTTGACAAGCAAAAGATTA
AAGAATTAGAGCCTAATGTGATTTTAGGGGCTAATGGCATAGACAGGCATGAAAACATTATCGGGCATGGTTATCAAAAA
GATTGGAGCACCATGAATTTTGCGAAGTTGAGTGAAAACTTCGTTGAAGAAGCCCTAAAATTAAAGCCTAACAACCAGGT
GTTTTTGAATTTCAAAGTGAAAAAGATTGAAAAACGCAACGACACTTACGCCGTAATTTCAGAAGACGCTGAAGAAGTGT
ATGCTAAATTCGTGCTGGTCAATGCCGGCTCTTACGCTTTGCCTTTGGCTCAGAGCATGGGCTATGGCCTAGATTTAGGG
TGCTTGCCTGTGGCGGGTAGCTTTTATTTTGTGCCGGATTTATTAAGGGGCAAGGTTTATACCGTTCAAAACCCCAAGCT
CCCTTTTGCAGCCGTGCATGGCGACCCTGATGCTGTCATTAAAGGAAAAACACGAATCGGGCCTACCGCTTTAACGATGC
CTAAATTAGAACGCAACAAATGCTGGCTTAAGGGCATTAGTTTGGAATTGTTGAAAATGGATTTGAATAAAGATGTGTTT
AAAATCGCATTTGATTTGATGAGCGATAAAGAAATCCGTAATTATGTGTTTAAAAACATGGTTTTTGAATTGCCCGTTAT
CGGTAAAAGGAAATTTTTAAAAGACGCTCAAAAAATCATCCCCTCTCTTAGCCTAGAAGATTTAGAATACGCTCATGGTT
TTGGCGAAGTGCGCCCGCAAGTTTTAGACAGAACCAAGCGAAAACTGGAATTAGGCGAAAAAAAGATTTGCACCCATAAA
GGCATCACTTTTAACATGACCCCCTCTCCAGGCGCGACGAGTTGCTTGCAAAACGCCCTTGTGGATTCCCAAGAAATCGC
TGCGTATTTGGGCGAGAGCTTTGAATTGGAACGCTTTTATAAAGATTTATCTCCAGAAGAATTGGAAAATTAA

Upstream 100 bases:

>100_bases
TGAAAGATTTTGTCAATAAAACTTCAAGCCCTTTGAAGGCGAATTGATTTTCTTATACTATGATTACGATTTATCAATTT
AAAACATTTGGAGAAAGACA

Downstream 100 bases:

>100_bases
AAACGCATGCAAAAAGAACAAGAAGCCCAAGAAATCGCTAAAAAAGCCGTTCAAATCGTGTTTTTTTTAGGGCTTGTGGT
GGTGCTTTTGATGATGATAA

Product: hypothetical protein

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone] [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSIETNYTPEKAKKVRLSAYKTR
QYALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKEIFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYQK
DWSTMNFAKLSENFVEEALKLKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLG
CLPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNKCWLKGISLELLKMDLNKDVF
KIAFDLMSDKEIRNYVFKNMVFELPVIGKRKFLKDAQKIIPSLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHK
GITFNMTPSPGATSCLQNALVDSQEIAAYLGESFELERFYKDLSPEELEN

Sequences:

>Translated_450_residues
MSMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSIETNYTPEKAKKVRLSAYKTR
QYALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKEIFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYQK
DWSTMNFAKLSENFVEEALKLKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLG
CLPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNKCWLKGISLELLKMDLNKDVF
KIAFDLMSDKEIRNYVFKNMVFELPVIGKRKFLKDAQKIIPSLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHK
GITFNMTPSPGATSCLQNALVDSQEIAAYLGESFELERFYKDLSPEELEN
>Mature_449_residues
SMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSIETNYTPEKAKKVRLSAYKTRQ
YALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKEIFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYQKD
WSTMNFAKLSENFVEEALKLKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLGC
LPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNKCWLKGISLELLKMDLNKDVFK
IAFDLMSDKEIRNYVFKNMVFELPVIGKRKFLKDAQKIIPSLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHKG
ITFNMTPSPGATSCLQNALVDSQEIAAYLGESFELERFYKDLSPEELEN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family [H]

Homologues:

Organism=Escherichia coli, GI1788539, Length=456, Percent_Identity=24.780701754386, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006231 [H]

Pfam domain/function: PF06039 Mqo [H]

EC number: =1.1.5.4 [H]

Molecular weight: Translated: 50671; Mature: 50540

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSI
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
ETNYTPEKAKKVRLSAYKTRQYALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHEEECCCHHHHHHHHHHHHHHH
IFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYQKDWSTMNFAKLSENFVEEALK
HHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
LKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLG
CCCCCEEEEEEEEEEECCCCCCEEEECCCHHHHHHEEEEEECCCCHHHHHHHCCCCCCCC
CLPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNK
CHHCCCCEEECHHHHCCCEEEECCCCCCEEEECCCCCCEEECCCCCCCCEECCCCCCCCC
CWLKGISLELLKMDLNKDVFKIAFDLMSDKEIRNYVFKNMVFELPVIGKRKFLKDAQKII
HHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PSLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHKGITFNMTPSPGATSCLQNAL
CCCCHHHHHHHCCCHHCCHHHHHHHHHHHHCCCHHHHEECCEEEEECCCCCHHHHHHHHH
VDSQEIAAYLGESFELERFYKDLSPEELEN
CCHHHHHHHHCCCCCHHHHHHCCCHHHHCC
>Mature Secondary Structure 
SMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSI
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
ETNYTPEKAKKVRLSAYKTRQYALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHEEECCCHHHHHHHHHHHHHHH
IFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYQKDWSTMNFAKLSENFVEEALK
HHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
LKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLG
CCCCCEEEEEEEEEEECCCCCCEEEECCCHHHHHHEEEEEECCCCHHHHHHHCCCCCCCC
CLPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNK
CHHCCCCEEECHHHHCCCEEEECCCCCCEEEECCCCCCEEECCCCCCCCEECCCCCCCCC
CWLKGISLELLKMDLNKDVFKIAFDLMSDKEIRNYVFKNMVFELPVIGKRKFLKDAQKII
HHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
PSLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHKGITFNMTPSPGATSCLQNAL
CCCCHHHHHHHCCCHHCCHHHHHHHHHHHHCCCHHHHEECCEEEEECCCCCHHHHHHHHH
VDSQEIAAYLGESFELERFYKDLSPEELEN
CCHHHHHHHHCCCCCHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA