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The map label for this gene is bioD [H]

Identifier: 108562452

GI number: 108562452

Start: 30544

End: 31200

Strand: Reverse

Name: bioD [H]

Synonym: HPAG1_0027

Alternate gene names: 108562452

Gene position: 31200-30544 (Counterclockwise)

Preceding gene: 108562453

Following gene: 108562449

Centisome position: 1.95

GC content: 40.18

Gene sequence:

>657_bases
ATGCTCTTTATCAGCGCGACTAACACCAATGCCGGAAAAACCACATGCGCTAGGCTATTAGCCCAATATTGCAACGCTTG
TGGCGTCAGAACGATTCTATTAAAGCCCATTGAAACAGGCGTTAATGATGCAACCAACCACTCTAGCGATGCGCATTTGT
TCTTGCAAGATAACCGCCTTTTGGATCGCTCTTTAACCTTAAAAGACATTTCATTCTATCGTTATCATAAAGCTTCAGCC
CCTCTCATCGCCCAACAAGAAGAAGATCCAAACGCCCCCATTGACACCAATCATTTAATCCAACGCCTCCAAAATTTCAC
CAAAACTTACGATTTAGTCATCGTTGAAGGGGCTGGGGGGCTATGCGTGCCTATCACTTTAGAAGAAAACATGCTAAATT
TTGCCCTAAAATTAAAAGCCAAAATGCTTTTGATTAGCCATGACAATTTGGGCTTGATCAATGATTGTTTGCTGAATGAC
TTTTTATTGAAATCCCACCAACTAGACTATAAAATCGCTATCAATTTGAGGGAAAATAACACCGCTTTTCACAGCATCAG
TTTGCCCTATATTGAGCTTTTTAATACACGCTCCAATAACCCCATTGTGATTTTCCAACAAAGCCTGAAAGAATTAATGA
GCTTTGCTCTTAAATAA

Upstream 100 bases:

>100_bases
AGTCCCAAGAGAAGCGCTAAAGAATGTGAAGTTACCACAAATTAAAAATGTATTGACCGCTCAAATCTTTGAGGGTGCTT
ACCAGTTTAAAAGTTAAACC

Downstream 100 bases:

>100_bases
AGTGCAAACAGAACGCACGCTGATAAAAAAGCCCATTAACAGCAAAGCGTATAAAATCCAGCTAAAAATGGGTTTTGAAA
TGTCAGTGCTCTCTTTTAAG

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDATNHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKASA
PLIAQQEEDPNAPIDTNHLIQRLQNFTKTYDLVIVEGAGGLCVPITLEENMLNFALKLKAKMLLISHDNLGLINDCLLND
FLLKSHQLDYKIAINLRENNTAFHSISLPYIELFNTRSNNPIVIFQQSLKELMSFALK

Sequences:

>Translated_218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDATNHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKASA
PLIAQQEEDPNAPIDTNHLIQRLQNFTKTYDLVIVEGAGGLCVPITLEENMLNFALKLKAKMLLISHDNLGLINDCLLND
FLLKSHQLDYKIAINLRENNTAFHSISLPYIELFNTRSNNPIVIFQQSLKELMSFALK
>Mature_218_residues
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDATNHSSDAHLFLQDNRLLDRSLTLKDISFYRYHKASA
PLIAQQEEDPNAPIDTNHLIQRLQNFTKTYDLVIVEGAGGLCVPITLEENMLNFALKLKAKMLLISHDNLGLINDCLLND
FLLKSHQLDYKIAINLRENNTAFHSISLPYIELFNTRSNNPIVIFQQSLKELMSFALK

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24550; Mature: 24550

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDATNHSSDAHLFLQDNRL
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCCCCEEEEEECCCE
LDRSLTLKDISFYRYHKASAPLIAQQEEDPNAPIDTNHLIQRLQNFTKTYDLVIVEGAGG
ECCCCCHHHHHEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCC
LCVPITLEENMLNFALKLKAKMLLISHDNLGLINDCLLNDFLLKSHQLDYKIAINLRENN
EEEEEEECCHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
TAFHSISLPYIELFNTRSNNPIVIFQQSLKELMSFALK
CEEEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MLFISATNTNAGKTTCARLLAQYCNACGVRTILLKPIETGVNDATNHSSDAHLFLQDNRL
CEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCCCCCCEEEEEECCCE
LDRSLTLKDISFYRYHKASAPLIAQQEEDPNAPIDTNHLIQRLQNFTKTYDLVIVEGAGG
ECCCCCHHHHHEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCC
LCVPITLEENMLNFALKLKAKMLLISHDNLGLINDCLLNDFLLKSHQLDYKIAINLRENN
EEEEEEECCHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCC
TAFHSISLPYIELFNTRSNNPIVIFQQSLKELMSFALK
CEEEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]