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The map label for this gene is ytnA [H]

Identifier: 107023455

GI number: 107023455

Start: 2103683

End: 2105089

Strand: Reverse

Name: ytnA [H]

Synonym: Bcen_1906

Alternate gene names: 107023455

Gene position: 2105089-2103683 (Counterclockwise)

Preceding gene: 107023456

Following gene: 107023454

Centisome position: 63.9

GC content: 67.8

Gene sequence:

>1407_bases
ATGGTGGTGCAGGGGAGTGGTAACGCAGTGACACAACAACAACGGTCGTTCGACGCTATCGTCGCGCGAGAACAAGGGTT
GCGCCACGCGCTGACGTCGGGGCAGATGGCGATGATCGCGATCGGCGGCGCGATCGGCACGGGGCTGTTCCTCGGCAGCG
GGTTCGCGATCGGGCTCGCCGGCCCGAGCGTGCTGGTGTCCTATGCGATCGGCGCGCTGATCGCGCTGCTGCTGATGGGC
GCGCTCGCGGAAATGACCGTCGCGCATCCGACGGCCGGCTCGTTCGGCGCCTATGCCGAGCATTACGTCGGCCCGCTCGC
GGGCTTCCTGGTGCGCTACGCGTACTGGTTCGCGGTCGTGTTCGCGATCGGCACCGAGATCAGCGCGATCGCGGTGTTCA
TGAAGTACTGGTTCCCGGCCGTGCCCGGCTGGTACTGGGTGATCGGCTTCTCGGCGCTGCTGATCGCGGTGAACCTCGCG
AGCGTCACGCTGTACGGGACGGTCGAATACGCGTTCTCACTGCTGAAGATCGCGGCGATCGTCGTGTTCATCGTGCTCGG
TGCGTATCTCGTGTGGGCGGCGCCGGTCGCGTCAGGCATCGGTTTCGCGAACTACACCGCGCACGGCGGCTTCATGCCGA
AGGGGCCGTGGGGTACGTGGGTCGCGGTGATCGTCGCGATCTTCAGCTACATGAGCATCGAAGCGGTCGCGATCGCGGCC
GGCGAGGCGCGCGATCCGCAGCACGCGGTCACGCGCGCATTCCGCTCGACCGTGTTCCGGCTCGTGCTGTTCTACCTGCT
GACGCTCGCGCTGATGCTCGCGATCGTGCCATGGACGCAGGCCGGCACCGACGAAAGCCCGTTCGTGAAGGTGATGGCCG
CGACGCACGTGCCGTATGCGGCCGGCGTGATCAACTTCGTGCTGTTGATCGCGGCGCTGTCGGCGATGAACAGCCAGCTC
TACGTGACGACACGCATGATGTTCAGCCTGTCGCGCGCGCGCCTCGCGCCCGCGGTGTTCGGCCGGCTCGGTGCGAACGG
CGTGCCGCGGGCGGCGCTGTGGATCTCGACGAGCGGCGTCGCGGTGGCGGCCGTGCTGGTCGCGCTCGCGCCCGACACCG
CGTTCACGGTGATGATGGCGATCGCCATGTTCGGCGCGCTGTTCACGTGGCTGATGATCTTCGTCACGCACCTGCGGTTC
CGTGCGCGGTATCGCGGCCCCGCGCTCGCGTTCCGGATGTGGGGGCACCCGTTCGGCAGCCTGCTCGGCGCGGGGCTCGT
CGCCGCGATCCTGCTGACGACCGCTTTCACGCGCGAATTCCGGATGACGATGGTGGTCGGCGTCGTATTCGTCGTGCTGC
TGACGCTCGCCTACGCGCTGCATTACCGGCACCAGCACGCGCGCTGA

Upstream 100 bases:

>100_bases
GAAGAGACGGTCGAAGTCGAGTAAGCGATAATTCGTTGTTCATGCGAACGGCGCGGGAAGTTCTCCGCGCCGTTTCGTTT
TATCCGGCGCCGGCGGCGCG

Downstream 100 bases:

>100_bases
CCGCGCCGGCGCGAGCACTCGCGCCGTTCGTCACACTCGCTAAGGTTCCGTTAAGCGAGCGGCGCCTACATTCGATCCTG
TCTGCATGGCGTGCCGATCC

Product: amino acid permease-associated region

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MVVQGSGNAVTQQQRSFDAIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMG
ALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLA
SVTLYGTVEYAFSLLKIAAIVVFIVLGAYLVWAAPVASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
GEARDPQHAVTRAFRSTVFRLVLFYLLTLALMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVLLIAALSAMNSQL
YVTTRMMFSLSRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRF
RARYRGPALAFRMWGHPFGSLLGAGLVAAILLTTAFTREFRMTMVVGVVFVVLLTLAYALHYRHQHAR

Sequences:

>Translated_468_residues
MVVQGSGNAVTQQQRSFDAIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMG
ALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLA
SVTLYGTVEYAFSLLKIAAIVVFIVLGAYLVWAAPVASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
GEARDPQHAVTRAFRSTVFRLVLFYLLTLALMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVLLIAALSAMNSQL
YVTTRMMFSLSRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRF
RARYRGPALAFRMWGHPFGSLLGAGLVAAILLTTAFTREFRMTMVVGVVFVVLLTLAYALHYRHQHAR
>Mature_468_residues
MVVQGSGNAVTQQQRSFDAIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMG
ALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLA
SVTLYGTVEYAFSLLKIAAIVVFIVLGAYLVWAAPVASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
GEARDPQHAVTRAFRSTVFRLVLFYLLTLALMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVLLIAALSAMNSQL
YVTTRMMFSLSRARLAPAVFGRLGANGVPRAALWISTSGVAVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRF
RARYRGPALAFRMWGHPFGSLLGAGLVAAILLTTAFTREFRMTMVVGVVFVVLLTLAYALHYRHQHAR

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=451, Percent_Identity=37.0288248337029, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI87081708, Length=448, Percent_Identity=36.8303571428571, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1786602, Length=448, Percent_Identity=33.9285714285714, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1786302, Length=445, Percent_Identity=32.1348314606742, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI48994972, Length=458, Percent_Identity=33.6244541484716, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790653, Length=418, Percent_Identity=33.7320574162679, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1789017, Length=419, Percent_Identity=33.890214797136, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=33.4975369458128, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1788480, Length=394, Percent_Identity=35.0253807106599, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081869, Length=246, Percent_Identity=27.6422764227642, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320772, Length=415, Percent_Identity=31.0843373493976, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6324061, Length=444, Percent_Identity=30.4054054054054, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6324553, Length=435, Percent_Identity=31.0344827586207, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324059, Length=476, Percent_Identity=31.3025210084034, Blast_Score=172, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6324924, Length=455, Percent_Identity=27.2527472527473, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6324990, Length=420, Percent_Identity=29.2857142857143, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322892, Length=429, Percent_Identity=30.5361305361305, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6321629, Length=418, Percent_Identity=25.5980861244019, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=416, Percent_Identity=25.7211538461538, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319824, Length=429, Percent_Identity=28.6713286713287, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=391, Percent_Identity=27.3657289002558, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319543, Length=402, Percent_Identity=27.363184079602, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319542, Length=396, Percent_Identity=26.5151515151515, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6321053, Length=396, Percent_Identity=26.2626262626263, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319608, Length=466, Percent_Identity=24.6781115879828, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6322967, Length=394, Percent_Identity=26.3959390862944, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6324981, Length=459, Percent_Identity=26.797385620915, Blast_Score=116, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320364, Length=501, Percent_Identity=22.1556886227545, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49961; Mature: 49961

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVQGSGNAVTQQQRSFDAIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCEEECC
GPSVLVSYAIGALIALLLMGALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGTVEYAFSLLKIAAI
HHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFIVLGAYLVWAAPVASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GEARDPQHAVTRAFRSTVFRLVLFYLLTLALMLAIVPWTQAGTDESPFVKVMAATHVPYA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHH
AGVINFVLLIAALSAMNSQLYVTTRMMFSLSRARLAPAVFGRLGANGVPRAALWISTSGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
AVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRARYRGPALAFRMWGHPFGS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHH
LLGAGLVAAILLTTAFTREFRMTMVVGVVFVVLLTLAYALHYRHQHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVQGSGNAVTQQQRSFDAIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCEEECC
GPSVLVSYAIGALIALLLMGALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGTVEYAFSLLKIAAI
HHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFIVLGAYLVWAAPVASGIGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GEARDPQHAVTRAFRSTVFRLVLFYLLTLALMLAIVPWTQAGTDESPFVKVMAATHVPYA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHH
AGVINFVLLIAALSAMNSQLYVTTRMMFSLSRARLAPAVFGRLGANGVPRAALWISTSGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
AVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRARYRGPALAFRMWGHPFGS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHH
LLGAGLVAAILLTTAFTREFRMTMVVGVVFVVLLTLAYALHYRHQHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]