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The map label for this gene is yeiA [H]

Identifier: 107023146

GI number: 107023146

Start: 1770519

End: 1771832

Strand: Reverse

Name: yeiA [H]

Synonym: Bcen_1595

Alternate gene names: 107023146

Gene position: 1771832-1770519 (Counterclockwise)

Preceding gene: 107023147

Following gene: 107023145

Centisome position: 53.78

GC content: 65.53

Gene sequence:

>1314_bases
ATGGCCGACCTTCGCTGCACCATCGCAGGCATCACTTCGCCGAATCCCTTCTGGCTGGCGTCCGCGCCGCCCACAGACAA
GGCCTACAACGTCAATCGCGCCTTCGAGGCGGGCTGGGGTGGCGTCGTCTGGAAGACGCTCGGGCTCGATCCGCACGTTG
TCAACGTCAGTTCGCGTTACGGCGCCGTGCAGTGGAATGGCCAGCGCATCGCGGGGCTGAACAACATCGAGCTGATCACC
GACCGTCCGCTCGACGTGAACCTGAGAGAGATCGCGCAGGTGAAGCGCGACTGGCCGGACCGCGCGCTGATCGTGTCGCT
GATGGTGCCGTGCAACGAGCGCGACTGGAAATGGATCCTGCCGCTCGTCGAGGACACCGGGGCCGACGCGGTCGAACTCA
ACTTCGGCTGCCCGCACGGGATGAGCGAGCGCGGCATGGGCGCGGCGGTCGGGCAGGTGCCCGAATACGTCGAGATGGTC
ACGCGCTGGGTGAAGGAAGGCACGAAGCTGCCGTGCCTCGTGAAGCTCACGCCGAACATCAGCGATATCCGGATGGGCTC
GCGCGCCGCGTACAAGGGCGGCGCGGACGGCGTGTCGCTGATCAACACGATCAACTCGATCGTCGCGGTCGATCTCGACC
AGATGGCGCCGATGCCGACCGTCGACGGCAAGGGCACGCACGGCGGCTATTGCGGGCCGGCGGTCAAGCCGATCGCACTG
AACATGGTCGCGGAGATCGCCCGCGACCCGGAAACACCGAACCTGCCGATCTCGGGCATCGGCGGCATCTCGTCGTGGCG
TGATGCGGCCGAGTTCATGGTGCTCGGCGCCGGCAGCGTGCAGGTGTGCACCGCCGCGATGCATTACGGATTCCGGATCG
TGTCGGATCTCGCCGATGGCCTGTCGAACTGGATGGACGAAAAGGGCTACGCGACGCTCGATGACATTCGCGGCCGCGCG
GTGCCGAACGTGACCGACTGGAAATACCTGAACCTGAAGTACGACATCAAGGCGCGCATCGACCAGGATCGCTGCATCCA
GTGCGGGCTGTGCCATATCGCATGCGAGGACACGTCGCACCAGGCGATCACGGCGACGAAGGACGGTGCGCGGCACTTCG
AAGTGGTCGATTCGGAATGCGTCGGGTGCAATCTTTGCATGCATGTGTGTCCGGTCGAGCAATGCATCACGATGGAGCGC
GTCGATTCGGGCGACTACGCGAACTGGACCACGCATCCGAACAATCCGGCGAGCGCGGAGGCTGGTGCGAGTGGCCCGGC
GGCGGCACCCGAGAAGCACGCGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGATCGACGCGACGCTCGCGGCGCGCGACGCGAAGGCGGCCTGACCGCGCGACGCACCGCACGCACACCGAACACGACC
CCATTCTCACGGAGCCGAAC

Downstream 100 bases:

>100_bases
CCGAGGTCCGGCGGTGCGGCATGGACCGCGCCGCCGCTTTTCGTTTCCCCGGGCCGGCATCGCACGATGCCGGCGCCGAC
GTTTTCGTGGAGCGCGTTCA

Product: dihydropyrimidine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MADLRCTIAGITSPNPFWLASAPPTDKAYNVNRAFEAGWGGVVWKTLGLDPHVVNVSSRYGAVQWNGQRIAGLNNIELIT
DRPLDVNLREIAQVKRDWPDRALIVSLMVPCNERDWKWILPLVEDTGADAVELNFGCPHGMSERGMGAAVGQVPEYVEMV
TRWVKEGTKLPCLVKLTPNISDIRMGSRAAYKGGADGVSLINTINSIVAVDLDQMAPMPTVDGKGTHGGYCGPAVKPIAL
NMVAEIARDPETPNLPISGIGGISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADGLSNWMDEKGYATLDDIRGRA
VPNVTDWKYLNLKYDIKARIDQDRCIQCGLCHIACEDTSHQAITATKDGARHFEVVDSECVGCNLCMHVCPVEQCITMER
VDSGDYANWTTHPNNPASAEAGASGPAAAPEKHAKAA

Sequences:

>Translated_437_residues
MADLRCTIAGITSPNPFWLASAPPTDKAYNVNRAFEAGWGGVVWKTLGLDPHVVNVSSRYGAVQWNGQRIAGLNNIELIT
DRPLDVNLREIAQVKRDWPDRALIVSLMVPCNERDWKWILPLVEDTGADAVELNFGCPHGMSERGMGAAVGQVPEYVEMV
TRWVKEGTKLPCLVKLTPNISDIRMGSRAAYKGGADGVSLINTINSIVAVDLDQMAPMPTVDGKGTHGGYCGPAVKPIAL
NMVAEIARDPETPNLPISGIGGISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADGLSNWMDEKGYATLDDIRGRA
VPNVTDWKYLNLKYDIKARIDQDRCIQCGLCHIACEDTSHQAITATKDGARHFEVVDSECVGCNLCMHVCPVEQCITMER
VDSGDYANWTTHPNNPASAEAGASGPAAAPEKHAKAA
>Mature_436_residues
ADLRCTIAGITSPNPFWLASAPPTDKAYNVNRAFEAGWGGVVWKTLGLDPHVVNVSSRYGAVQWNGQRIAGLNNIELITD
RPLDVNLREIAQVKRDWPDRALIVSLMVPCNERDWKWILPLVEDTGADAVELNFGCPHGMSERGMGAAVGQVPEYVEMVT
RWVKEGTKLPCLVKLTPNISDIRMGSRAAYKGGADGVSLINTINSIVAVDLDQMAPMPTVDGKGTHGGYCGPAVKPIALN
MVAEIARDPETPNLPISGIGGISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADGLSNWMDEKGYATLDDIRGRAV
PNVTDWKYLNLKYDIKARIDQDRCIQCGLCHIACEDTSHQAITATKDGARHFEVVDSECVGCNLCMHVCPVEQCITMERV
DSGDYANWTTHPNNPASAEAGASGPAAAPEKHAKAA

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=337, Percent_Identity=39.4658753709199, Blast_Score=230, Evalue=2e-60,
Organism=Escherichia coli, GI87082059, Length=400, Percent_Identity=43.75, Blast_Score=337, Evalue=7e-94,
Organism=Caenorhabditis elegans, GI71984108, Length=326, Percent_Identity=39.8773006134969, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322633, Length=323, Percent_Identity=25.3869969040248, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24640763, Length=309, Percent_Identity=42.7184466019417, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI18858217, Length=309, Percent_Identity=42.7184466019417, Blast_Score=243, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR012285 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: NA

Molecular weight: Translated: 47202; Mature: 47071

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLRCTIAGITSPNPFWLASAPPTDKAYNVNRAFEAGWGGVVWKTLGLDPHVVNVSSRY
CCCCEEEEEECCCCCCEEEECCCCCCCCEECCCHHHCCCCCEEEEECCCCCEEEEECCCC
GAVQWNGQRIAGLNNIELITDRPLDVNLREIAQVKRDWPDRALIVSLMVPCNERDWKWIL
CEEEECCEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEE
PLVEDTGADAVELNFGCPHGMSERGMGAAVGQVPEYVEMVTRWVKEGTKLPCLVKLTPNI
EEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCH
SDIRMGSRAAYKGGADGVSLINTINSIVAVDLDQMAPMPTVDGKGTHGGYCGPAVKPIAL
HHHCCCCCCCCCCCCCHHHHHHHHHHHHEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
NMVAEIARDPETPNLPISGIGGISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADG
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LSNWMDEKGYATLDDIRGRAVPNVTDWKYLNLKYDIKARIDQDRCIQCGLCHIACEDTSH
HHHHHHCCCCEEHHHHCCCCCCCCCCEEEEEEEEEEEECCCCCHHHCCCEEEEEECCCCC
QAITATKDGARHFEVVDSECVGCNLCMHVCPVEQCITMERVDSGDYANWTTHPNNPASAE
CEEEECCCCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
AGASGPAAAPEKHAKAA
CCCCCCCCCCHHHCCCC
>Mature Secondary Structure 
ADLRCTIAGITSPNPFWLASAPPTDKAYNVNRAFEAGWGGVVWKTLGLDPHVVNVSSRY
CCCEEEEEECCCCCCEEEECCCCCCCCEECCCHHHCCCCCEEEEECCCCCEEEEECCCC
GAVQWNGQRIAGLNNIELITDRPLDVNLREIAQVKRDWPDRALIVSLMVPCNERDWKWIL
CEEEECCEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEE
PLVEDTGADAVELNFGCPHGMSERGMGAAVGQVPEYVEMVTRWVKEGTKLPCLVKLTPNI
EEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCH
SDIRMGSRAAYKGGADGVSLINTINSIVAVDLDQMAPMPTVDGKGTHGGYCGPAVKPIAL
HHHCCCCCCCCCCCCCHHHHHHHHHHHHEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHHH
NMVAEIARDPETPNLPISGIGGISSWRDAAEFMVLGAGSVQVCTAAMHYGFRIVSDLADG
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LSNWMDEKGYATLDDIRGRAVPNVTDWKYLNLKYDIKARIDQDRCIQCGLCHIACEDTSH
HHHHHHCCCCEEHHHHCCCCCCCCCCEEEEEEEEEEEECCCCCHHHCCCEEEEEECCCCC
QAITATKDGARHFEVVDSECVGCNLCMHVCPVEQCITMERVDSGDYANWTTHPNNPASAE
CEEEECCCCCCEEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
AGASGPAAAPEKHAKAA
CCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 1719366 [H]