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The map label for this gene is groEL

Identifier: 107023131

GI number: 107023131

Start: 1753907

End: 1755529

Strand: Reverse

Name: groEL

Synonym: Bcen_1580

Alternate gene names: 107023131

Gene position: 1755529-1753907 (Counterclockwise)

Preceding gene: 107023132

Following gene: 107023130

Centisome position: 53.29

GC content: 66.17

Gene sequence:

>1623_bases
ATGACTGCAAAAGACGTGAAATTCCGCGATGGCGCGCGCCAGCAGATCGTCAAGGGCGTGAACGTGCTGGCCGACGCGGT
GAAGGTGACGCTCGGCCCGAAAGGCCGCAACGTCGTGATCGAGCGCGGCTTCGGCGCGCCGGTGATCACGAAGGACGGCG
TGTCGGTCGCGAAGGAAATCGAGCTGAAGGACCGCTTCGAGAACATGGGCGCGCAGATCGTCAAGCAGGTCGCGTCGAAG
ACGGCCGACGTGGCCGGCGACGGGACCACCACCGCCACCGTGCTCGCGCAGGCGATCGTGCAGGAAGGCATGAAGCACGT
CGCGGCCGGCATGAATCCGATGGATCTGAAGCGCGGCATCGACAAGGCCGTCGGCGCGGTGCTCGACGAGCTGCGCAAGC
TGTCCCGGCCGATTTCGACCCACAAGGAAATCGCGCAGGTCGGCGCGATTTCCGCGAACTCGGACGAGGCGATCGGCAAG
ATCATCGCCGACGCGATGGAGAAGGTCGGCAAGGACGGCGTGATCACCGTCGAGGACGGCAAGTCGCTCGAGAACGAACT
CGACGTGGTCGAAGGCATGCAGTTCGATCGCGGTTACGTGAGCCCGTATTTCATCAACGATCCGGCGAAGCAGGCGGCCT
ATCTCGACGACGCGCTGATTCTGCTGCACGACAAGAAGATTTCCAGTGTCCGCGACCTGCTGCCGATTCTCGAAGCGGCG
TCCAAGGCCGGCAAGCCGCTGCTGATCGTGGCCGAGGATGTCGAGGCCGAAGCGCTCGCGACGCTCGTCGTGAATTCGAT
GCGCGGCATCCTGAAGGTCGCCGCCGTCAAGGCGCCGGGTTTCGGCGACCGGCGCAAGGCCATGCTGGAGGATCTCGCGA
TCCTGACCGGCGCGACCGTCATCTCGGAGGAAACCGGCAAGCAGCTCGACAAGGCCACGCTGGAGGATCTTGGCAGTGCG
AAGCGTGTCGAGGTGCGCAAGGACGACACGATCATCATCGACGGCGCGGGCGATGCGGCACGCATCGAGGCGCGCGTGAA
GTCGATTCGCGTGCAGATCGACGAAGCGACGAGCGACTACGATCGTGAGAAGCTGCAGGAGCGTGTCGCGAAGCTCGCGG
GCGGCGTGGCGGTGATCAAGGTCGGCGCGGTTACCGAAGTCGAAATGAAGGAGAAGAAGGACCGGGTCGACGATGCGCTG
CATGCGACGCGTGCGGCGGTCGAGGAGGGCATCGTGCCGGGCGGCGGCGTCGCGCTGCTGCGTGCGCGCGCGGCGCTGTC
GGACATCCGGGGCGCGAATGCGGACCAGGATGCCGGCATCCGGATCGTGCTGCGTGCGCTGGAGGCGCCGCTGCGTGTCA
TCGCGGCCAATGCCGGCGACGAACCGTCGGTCGTGATCTCGAAGGTGCTCGAAGGCAAAGGGAACTTCGGCTACAACGCG
GCGACCGGCGAGTACGGCGATCTGGTGGACGCAGGCGTGGTCGACCCGACCAAGGTCACGCGTACCGCGCTGCAGAACGC
CGCGTCGATCGCGAGCCTGGTGTTGACGACCGATGCGACCGTCGCCCAGGCGCCGAAAGAGGAGAGCGCCGAGTCGGCCC
CCGCGCCCGAACTCGGCTACTGA

Upstream 100 bases:

>100_bases
CCGCCAGGAAAGCGGCCTGAATGCCGATTCGACCGCGTCGCACGGGTGTGTGCCCGCTGCGCGCGGCATCCCGTTCAACG
ACTGTATCCGGAGCAAGAAA

Downstream 100 bases:

>100_bases
CCGGCGTCGCAGGCCTGCCTGCGATCGTCGCACAGCCGCTGGCCGGAGCGGCTTTGGTCGGCGCGCGCGACAGTGGGGAC
GCGCCGCGCCGCTTTTTCAT

Product: chaperonin GroEL

Products: NA

Alternate protein names: GroEL protein 2; Protein Cpn60 2

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MTAKDVKFRDGARQQIVKGVNVLADAVKVTLGPKGRNVVIERGFGAPVITKDGVSVAKEIELKDRFENMGAQIVKQVASK
TADVAGDGTTTATVLAQAIVQEGMKHVAAGMNPMDLKRGIDKAVGAVLDELRKLSRPISTHKEIAQVGAISANSDEAIGK
IIADAMEKVGKDGVITVEDGKSLENELDVVEGMQFDRGYVSPYFINDPAKQAAYLDDALILLHDKKISSVRDLLPILEAA
SKAGKPLLIVAEDVEAEALATLVVNSMRGILKVAAVKAPGFGDRRKAMLEDLAILTGATVISEETGKQLDKATLEDLGSA
KRVEVRKDDTIIIDGAGDAARIEARVKSIRVQIDEATSDYDREKLQERVAKLAGGVAVIKVGAVTEVEMKEKKDRVDDAL
HATRAAVEEGIVPGGGVALLRARAALSDIRGANADQDAGIRIVLRALEAPLRVIAANAGDEPSVVISKVLEGKGNFGYNA
ATGEYGDLVDAGVVDPTKVTRTALQNAASIASLVLTTDATVAQAPKEESAESAPAPELGY

Sequences:

>Translated_540_residues
MTAKDVKFRDGARQQIVKGVNVLADAVKVTLGPKGRNVVIERGFGAPVITKDGVSVAKEIELKDRFENMGAQIVKQVASK
TADVAGDGTTTATVLAQAIVQEGMKHVAAGMNPMDLKRGIDKAVGAVLDELRKLSRPISTHKEIAQVGAISANSDEAIGK
IIADAMEKVGKDGVITVEDGKSLENELDVVEGMQFDRGYVSPYFINDPAKQAAYLDDALILLHDKKISSVRDLLPILEAA
SKAGKPLLIVAEDVEAEALATLVVNSMRGILKVAAVKAPGFGDRRKAMLEDLAILTGATVISEETGKQLDKATLEDLGSA
KRVEVRKDDTIIIDGAGDAARIEARVKSIRVQIDEATSDYDREKLQERVAKLAGGVAVIKVGAVTEVEMKEKKDRVDDAL
HATRAAVEEGIVPGGGVALLRARAALSDIRGANADQDAGIRIVLRALEAPLRVIAANAGDEPSVVISKVLEGKGNFGYNA
ATGEYGDLVDAGVVDPTKVTRTALQNAASIASLVLTTDATVAQAPKEESAESAPAPELGY
>Mature_539_residues
TAKDVKFRDGARQQIVKGVNVLADAVKVTLGPKGRNVVIERGFGAPVITKDGVSVAKEIELKDRFENMGAQIVKQVASKT
ADVAGDGTTTATVLAQAIVQEGMKHVAAGMNPMDLKRGIDKAVGAVLDELRKLSRPISTHKEIAQVGAISANSDEAIGKI
IADAMEKVGKDGVITVEDGKSLENELDVVEGMQFDRGYVSPYFINDPAKQAAYLDDALILLHDKKISSVRDLLPILEAAS
KAGKPLLIVAEDVEAEALATLVVNSMRGILKVAAVKAPGFGDRRKAMLEDLAILTGATVISEETGKQLDKATLEDLGSAK
RVEVRKDDTIIIDGAGDAARIEARVKSIRVQIDEATSDYDREKLQERVAKLAGGVAVIKVGAVTEVEMKEKKDRVDDALH
ATRAAVEEGIVPGGGVALLRARAALSDIRGANADQDAGIRIVLRALEAPLRVIAANAGDEPSVVISKVLEGKGNFGYNAA
TGEYGDLVDAGVVDPTKVTRTALQNAASIASLVLTTDATVAQAPKEESAESAPAPELGY

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family

Homologues:

Organism=Homo sapiens, GI41399285, Length=527, Percent_Identity=53.8899430740038, Blast_Score=557, Evalue=1e-158,
Organism=Homo sapiens, GI31542947, Length=527, Percent_Identity=53.8899430740038, Blast_Score=557, Evalue=1e-158,
Organism=Escherichia coli, GI1790586, Length=531, Percent_Identity=71.7514124293785, Blast_Score=764, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17555558, Length=530, Percent_Identity=53.3962264150943, Blast_Score=560, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI193210679, Length=212, Percent_Identity=54.2452830188679, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17564182, Length=556, Percent_Identity=24.6402877697842, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323288, Length=524, Percent_Identity=52.8625954198473, Blast_Score=548, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6322524, Length=529, Percent_Identity=23.6294896030246, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641193, Length=527, Percent_Identity=54.26944971537, Blast_Score=567, Evalue=1e-162,
Organism=Drosophila melanogaster, GI24641191, Length=527, Percent_Identity=54.26944971537, Blast_Score=567, Evalue=1e-162,
Organism=Drosophila melanogaster, GI45550936, Length=527, Percent_Identity=53.5104364326376, Blast_Score=563, Evalue=1e-160,
Organism=Drosophila melanogaster, GI45550132, Length=527, Percent_Identity=53.5104364326376, Blast_Score=563, Evalue=1e-160,
Organism=Drosophila melanogaster, GI45550935, Length=527, Percent_Identity=53.5104364326376, Blast_Score=563, Evalue=1e-160,
Organism=Drosophila melanogaster, GI17864606, Length=526, Percent_Identity=44.4866920152091, Blast_Score=464, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24584129, Length=529, Percent_Identity=40.2646502835539, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19921262, Length=529, Percent_Identity=40.2646502835539, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24583944, Length=569, Percent_Identity=22.4956063268893, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): CH602_BURCA (Q1BV70)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621458.1
- ProteinModelPortal:   Q1BV70
- SMR:   Q1BV70
- STRING:   Q1BV70
- GeneID:   4092865
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_1580
- eggNOG:   COG0459
- HOGENOM:   HBG625289
- OMA:   DVKFHDS
- ProtClustDB:   PRK12849
- BioCyc:   BCEN331271:BCEN_1580-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00600
- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423
- PANTHER:   PTHR11353
- PRINTS:   PR00298
- TIGRFAMs:   TIGR02348

Pfam domain/function: PF00118 Cpn60_TCP1; SSF48592 GroEL-ATPase

EC number: NA

Molecular weight: Translated: 56811; Mature: 56679

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKDVKFRDGARQQIVKGVNVLADAVKVTLGPKGRNVVIERGFGAPVITKDGVSVAKEI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCEEECCCHHHHHHH
ELKDRFENMGAQIVKQVASKTADVAGDGTTTATVLAQAIVQEGMKHVAAGMNPMDLKRGI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DKAVGAVLDELRKLSRPISTHKEIAQVGAISANSDEAIGKIIADAMEKVGKDGVITVEDG
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCC
KSLENELDVVEGMQFDRGYVSPYFINDPAKQAAYLDDALILLHDKKISSVRDLLPILEAA
CCHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
SKAGKPLLIVAEDVEAEALATLVVNSMRGILKVAAVKAPGFGDRRKAMLEDLAILTGATV
HHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHH
ISEETGKQLDKATLEDLGSAKRVEVRKDDTIIIDGAGDAARIEARVKSIRVQIDEATSDY
HHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHEEEECCCCHH
DREKLQERVAKLAGGVAVIKVGAVTEVEMKEKKDRVDDALHATRAAVEEGIVPGGGVALL
HHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RARAALSDIRGANADQDAGIRIVLRALEAPLRVIAANAGDEPSVVISKVLEGKGNFGYNA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHCCCCCCCCC
ATGEYGDLVDAGVVDPTKVTRTALQNAASIASLVLTTDATVAQAPKEESAESAPAPELGY
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAKDVKFRDGARQQIVKGVNVLADAVKVTLGPKGRNVVIERGFGAPVITKDGVSVAKEI
CCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCEEECCCHHHHHHH
ELKDRFENMGAQIVKQVASKTADVAGDGTTTATVLAQAIVQEGMKHVAAGMNPMDLKRGI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DKAVGAVLDELRKLSRPISTHKEIAQVGAISANSDEAIGKIIADAMEKVGKDGVITVEDG
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCC
KSLENELDVVEGMQFDRGYVSPYFINDPAKQAAYLDDALILLHDKKISSVRDLLPILEAA
CCHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
SKAGKPLLIVAEDVEAEALATLVVNSMRGILKVAAVKAPGFGDRRKAMLEDLAILTGATV
HHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHH
ISEETGKQLDKATLEDLGSAKRVEVRKDDTIIIDGAGDAARIEARVKSIRVQIDEATSDY
HHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHEEEECCCCHH
DREKLQERVAKLAGGVAVIKVGAVTEVEMKEKKDRVDDALHATRAAVEEGIVPGGGVALL
HHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RARAALSDIRGANADQDAGIRIVLRALEAPLRVIAANAGDEPSVVISKVLEGKGNFGYNA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHCCCCCCCCC
ATGEYGDLVDAGVVDPTKVTRTALQNAASIASLVLTTDATVAQAPKEESAESAPAPELGY
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA