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The map label for this gene is trxB [H]

Identifier: 107023021

GI number: 107023021

Start: 1628062

End: 1629732

Strand: Reverse

Name: trxB [H]

Synonym: Bcen_1469

Alternate gene names: 107023021

Gene position: 1629732-1628062 (Counterclockwise)

Preceding gene: 107023028

Following gene: 107023018

Centisome position: 49.47

GC content: 70.14

Gene sequence:

>1671_bases
ATGCCGGCTCGCGTGGCGATTCGGCGACGAGTCGCAGCAGCCGACGTGCCCGCAGATCAGGCACATCCGCAAATGCACCC
AGCGGCTGCCCGATCTGATGCATTCCTCACAGTAGTCCTTGTCGGTGTCGAACACGCGTGCTTCGTCGAGATGCGTACAG
GCGTTGGCCATCTTGCGCTCCGATGCCGGCGCGGGAGCGACGCTTGCGACGGGCCGGCGCGAGGCCGCAAGCGGGACGGA
TACGCGACATTGTGCGGCGTCGCGGCGCGGCCGGACCTTAATTGTCATGAAGCGGCCCGCGCGGCGCGTGCCGGCGGCGT
ACAGTCGCGGATGCGTCCGGCCGCGGCACCGCCGCACCGGCCGGACCGCATTCGACATCGACATCATCGGGAGGCGCTCA
TGGAGCAACCGCAACACGTGCGGATCGTCGGCCTGCCGCGCAGCCGGGACGCGTACGCGATCCGCGATTTCCTGCAGCGG
CGCATGATCGCGTACGACTGGTGCGAGCTGACGTCGGACGCTGACTGCGCGCAGGTGCTCGGCATCGCGCCGCTTCGCGA
CATCCGGCTGCCGGTCGTGATCTTTCCGGACGGCTCGCGCCTGTACCAGCCGACGCTGGCCGAGATCGCCGCGCGGCTCG
GCTGGGTCGCGCGGCCGCGCTTCGTCGAATACGACGTGTCGATCTACGGCGCGGGACCGGCCGGGCTGTCGGCGGCGGTC
TACGCGGCGTCCGAAGGGCTGCGCGCGGTCGTGATCGAGCGCGGCGCGATCGGCGGGCAGGCCGGCACGAGTTCGCTGAT
CGAGAACTACATGGGCTTCCCCGACGGCATCCCGGGCGCGGAGCTTGCCGAACGCGCGCGCGAGCAGGCGGTGAAGTTCG
GCGTCGAGCTGCTGACGATGCGCGAGGGCGTGCATGCGACGTTCGTCGACGGCAAGATCCGCGTCGAGCTCGCCGACGGG
TCGATCCTGATCGCCCGCGCGAACATCTGCGCGACCGGCATCGAATATCGCAGCCTCGGGCTGCCGGAGGAACCGGCGTT
TCTCAACGCGGGGCTGTTCTACGGCGCGGGGTCGAGCGAAGCGCCGATGTGCGCGGGCGAGCAGGTGTTCATCGTCGGCG
GCGGCAATTCGGCCGGCCAGGCCGCGATGAATTTCTCCCGGCATGCGCGCCAGGTGACGATGCTCGTGCGCGGCGCGTCG
CTCGCCGACACGCTGTCGCGCTACCTGATCGACCGGATCGAACGCACGCCGAACATCGAGGTCCGCTACCGGTCGAGCGT
CGCCGCGCTGCACGGCGACGGCTGGCTCGACGCGATCGAGCTTCGCTCGGCGGACGGCACGCGCGAACGGCTGCCGGCCA
CGCGCCTGTTCGTGTGCATCGGCGGCGCGCCGAATACCGACTGGGCGAGGGACACCGACATCATTCGCAATCCGGACGGT
TATCTCGTCACCGGCGGCGATCTGTACGATTGTCCGGCGTTCGAGCGCGTATGGCCGCTCGAGCGCCGGCCGTACCACCT
GGAAACCAGCGTGCCGGGATCGTTCGCGGCCGGCGACGTGCGATCGGGCTCGGTCAAGCGCGTCGCGTCGGCGGTCGGCG
AAGGCGCGATGGCCGTGACCTTCGTGCACCGGTTTCTCGGCGAGGATGCGCATCGGCTCGCGCGCGCGTGA

Upstream 100 bases:

>100_bases
ACGACGGAATCTCGCCCGCGACGACTTCGTCCGCGTAGCACCAGATCCAGCGCTCGCCGGGCTCGATCGAGCGGACGAGC
CGGTGGCCGGTGTCGTGGAA

Downstream 100 bases:

>100_bases
CGCGCTCGCGGGCCGTTCGATGCGTTCATCGCGCGTCGGCTTGCGTCGCGTCGCGCAACCCGCCCCGGCCGGCGTGCGCC
GGCGGCGTCCACCCGCCGCC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MPARVAIRRRVAAADVPADQAHPQMHPAAARSDAFLTVVLVGVEHACFVEMRTGVGHLALRCRRGSDACDGPARGRKRDG
YATLCGVAARPDLNCHEAARAARAGGVQSRMRPAAAPPHRPDRIRHRHHREALMEQPQHVRIVGLPRSRDAYAIRDFLQR
RMIAYDWCELTSDADCAQVLGIAPLRDIRLPVVIFPDGSRLYQPTLAEIAARLGWVARPRFVEYDVSIYGAGPAGLSAAV
YAASEGLRAVVIERGAIGGQAGTSSLIENYMGFPDGIPGAELAERAREQAVKFGVELLTMREGVHATFVDGKIRVELADG
SILIARANICATGIEYRSLGLPEEPAFLNAGLFYGAGSSEAPMCAGEQVFIVGGGNSAGQAAMNFSRHARQVTMLVRGAS
LADTLSRYLIDRIERTPNIEVRYRSSVAALHGDGWLDAIELRSADGTRERLPATRLFVCIGGAPNTDWARDTDIIRNPDG
YLVTGGDLYDCPAFERVWPLERRPYHLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLGEDAHRLARA

Sequences:

>Translated_556_residues
MPARVAIRRRVAAADVPADQAHPQMHPAAARSDAFLTVVLVGVEHACFVEMRTGVGHLALRCRRGSDACDGPARGRKRDG
YATLCGVAARPDLNCHEAARAARAGGVQSRMRPAAAPPHRPDRIRHRHHREALMEQPQHVRIVGLPRSRDAYAIRDFLQR
RMIAYDWCELTSDADCAQVLGIAPLRDIRLPVVIFPDGSRLYQPTLAEIAARLGWVARPRFVEYDVSIYGAGPAGLSAAV
YAASEGLRAVVIERGAIGGQAGTSSLIENYMGFPDGIPGAELAERAREQAVKFGVELLTMREGVHATFVDGKIRVELADG
SILIARANICATGIEYRSLGLPEEPAFLNAGLFYGAGSSEAPMCAGEQVFIVGGGNSAGQAAMNFSRHARQVTMLVRGAS
LADTLSRYLIDRIERTPNIEVRYRSSVAALHGDGWLDAIELRSADGTRERLPATRLFVCIGGAPNTDWARDTDIIRNPDG
YLVTGGDLYDCPAFERVWPLERRPYHLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLGEDAHRLARA
>Mature_555_residues
PARVAIRRRVAAADVPADQAHPQMHPAAARSDAFLTVVLVGVEHACFVEMRTGVGHLALRCRRGSDACDGPARGRKRDGY
ATLCGVAARPDLNCHEAARAARAGGVQSRMRPAAAPPHRPDRIRHRHHREALMEQPQHVRIVGLPRSRDAYAIRDFLQRR
MIAYDWCELTSDADCAQVLGIAPLRDIRLPVVIFPDGSRLYQPTLAEIAARLGWVARPRFVEYDVSIYGAGPAGLSAAVY
AASEGLRAVVIERGAIGGQAGTSSLIENYMGFPDGIPGAELAERAREQAVKFGVELLTMREGVHATFVDGKIRVELADGS
ILIARANICATGIEYRSLGLPEEPAFLNAGLFYGAGSSEAPMCAGEQVFIVGGGNSAGQAAMNFSRHARQVTMLVRGASL
ADTLSRYLIDRIERTPNIEVRYRSSVAALHGDGWLDAIELRSADGTRERLPATRLFVCIGGAPNTDWARDTDIIRNPDGY
LVTGGDLYDCPAFERVWPLERRPYHLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLGEDAHRLARA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=331, Percent_Identity=32.3262839879154, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87081763, Length=360, Percent_Identity=29.4444444444444, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320560, Length=339, Percent_Identity=32.1533923303835, Blast_Score=133, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6321898, Length=339, Percent_Identity=30.3834808259587, Blast_Score=126, Evalue=9e-30,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 60136; Mature: 60005

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARVAIRRRVAAADVPADQAHPQMHPAAARSDAFLTVVLVGVEHACFVEMRTGVGHLAL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCEEEEEECCCCCEEEE
RCRRGSDACDGPARGRKRDGYATLCGVAARPDLNCHEAARAARAGGVQSRMRPAAAPPHR
EEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCC
PDRIRHRHHREALMEQPQHVRIVGLPRSRDAYAIRDFLQRRMIAYDWCELTSDADCAQVL
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GIAPLRDIRLPVVIFPDGSRLYQPTLAEIAARLGWVARPRFVEYDVSIYGAGPAGLSAAV
CCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHH
YAASEGLRAVVIERGAIGGQAGTSSLIENYMGFPDGIPGAELAERAREQAVKFGVELLTM
HHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEH
REGVHATFVDGKIRVELADGSILIARANICATGIEYRSLGLPEEPAFLNAGLFYGAGSSE
HCCCEEEEECCEEEEEEECCCEEEEECCHHHCCCCHHHCCCCCCCCEEECCEEECCCCCC
APMCAGEQVFIVGGGNSAGQAAMNFSRHARQVTMLVRGASLADTLSRYLIDRIERTPNIE
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHHHHHCCCCEE
VRYRSSVAALHGDGWLDAIELRSADGTRERLPATRLFVCIGGAPNTDWARDTDIIRNPDG
EEECCCEEEEECCCCEEEEEEECCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCEECCCC
YLVTGGDLYDCPAFERVWPLERRPYHLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVT
CEEECCCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH
FVHRFLGEDAHRLARA
HHHHHHCCHHHHHHCC
>Mature Secondary Structure 
PARVAIRRRVAAADVPADQAHPQMHPAAARSDAFLTVVLVGVEHACFVEMRTGVGHLAL
CCHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCEEEEEECCCCCEEEE
RCRRGSDACDGPARGRKRDGYATLCGVAARPDLNCHEAARAARAGGVQSRMRPAAAPPHR
EEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCCC
PDRIRHRHHREALMEQPQHVRIVGLPRSRDAYAIRDFLQRRMIAYDWCELTSDADCAQVL
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
GIAPLRDIRLPVVIFPDGSRLYQPTLAEIAARLGWVARPRFVEYDVSIYGAGPAGLSAAV
CCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHH
YAASEGLRAVVIERGAIGGQAGTSSLIENYMGFPDGIPGAELAERAREQAVKFGVELLTM
HHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEH
REGVHATFVDGKIRVELADGSILIARANICATGIEYRSLGLPEEPAFLNAGLFYGAGSSE
HCCCEEEEECCEEEEEEECCCEEEEECCHHHCCCCHHHCCCCCCCCEEECCEEECCCCCC
APMCAGEQVFIVGGGNSAGQAAMNFSRHARQVTMLVRGASLADTLSRYLIDRIERTPNIE
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHHHHHCCCCEE
VRYRSSVAALHGDGWLDAIELRSADGTRERLPATRLFVCIGGAPNTDWARDTDIIRNPDG
EEECCCEEEEECCCCEEEEEEECCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCEECCCC
YLVTGGDLYDCPAFERVWPLERRPYHLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVT
CEEECCCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH
FVHRFLGEDAHRLARA
HHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]