BacMap

Definition	Burkholderia cenocepacia AU 1054 chromosome 1, complete sequence.
Accession	NC_008060
Length	3,294,563

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The map label for this gene is ucpA [C]

Identifier: 107022938

GI number: 107022938

Start: 1524001

End: 1524756

Strand: Reverse

Name: ucpA [C]

Synonym: Bcen_1386

Alternate gene names: 107022938

Gene position: 1524756-1524001 (Counterclockwise)

Preceding gene: 107022939

Following gene: 107022937

Centisome position: 46.28

GC content: 71.3

Gene sequence:

>756_bases
GTGCAGGTGAACGCGACTCACGATCCAGCCAAACCGCCGCTCGCCGGCCGGACCGCACTCGTGACCGGGGGCGGCCGCGG
TCTCGGCGAAGCCATTTGCGAAGAGCTTGCGCAGCACGGCGCGCACGTCGTCGTCGCCGATCTCGACGGCGACCGCGCGG
CGGCCGTCGCGCAGCGGCTCGAGCGGCACGGCGGACAGGCGGTCGGCCGGCCGCTCGACGTGCGCGACGAGGCATCGGTG
CTGCAGGTCGTGCACGACGCGCGCGAATCGCTCGGCGAGCTCGACGTGATCGTCAACAACGCGGCGATCGACGTGACCGC
GCCGATCGACGACGTGAGCGTCGACGCGTGGCAGCAGGTGCTGATGACGAACCTGTTCGGCCCGTACCTGATGTGTCACG
CGGCCGTGCCGATGATGAAGGCGCGCGGCAACGGGCATATCGTCAACATCGCGTCGACCGCGTCCAAGCGCGCGTGGCCG
AACGCGTCCGCGTATCACGCGACGAAGTGGGGGCTGCTCGGGCTGTCGCACGCGCTGCACGCCGAACTGCGGCCGAGCGG
CGTGCGCGTGTCGGCGATCGTCGCGGGCGGGATGCGCACGCCGTTCCTGCTCGACCGTTTCCCGGACATCGACGAGGACA
CGCTGCAGCCGCCGGAGCACGTCGCGGCCGCCGTGCGCTTCGTGCTGACGCAGCCGCCGGGCACCGTGGTGCCGGAGCTG
ATGGTGCTGCCGATGAAGGAGACGTCATGGCCCTGA

Upstream 100 bases:

>100_bases
GCACACGCAGGCCGGCACGGTTTTCGCTGTACCTCATGCACGGACGGTTGTCGCGACAAGTGTCGCCGTCAACCGGATGG
ATTTCCGACATCGACAGGAG

Downstream 100 bases:

>100_bases
AGCGCGAACGGCGGCTGCCCGGCGCGGTGCTGCTCGACAAGGACGGCACGCTGCTCGACGACGTGCCGTACAACGTCGAC
CCCGCGCGCATGCGCCTCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MQVNATHDPAKPPLAGRTALVTGGGRGLGEAICEELAQHGAHVVVADLDGDRAAAVAQRLERHGGQAVGRPLDVRDEASV
LQVVHDARESLGELDVIVNNAAIDVTAPIDDVSVDAWQQVLMTNLFGPYLMCHAAVPMMKARGNGHIVNIASTASKRAWP
NASAYHATKWGLLGLSHALHAELRPSGVRVSAIVAGGMRTPFLLDRFPDIDEDTLQPPEHVAAAVRFVLTQPPGTVVPEL
MVLPMKETSWP

Sequences:

>Translated_251_residues
MQVNATHDPAKPPLAGRTALVTGGGRGLGEAICEELAQHGAHVVVADLDGDRAAAVAQRLERHGGQAVGRPLDVRDEASV
LQVVHDARESLGELDVIVNNAAIDVTAPIDDVSVDAWQQVLMTNLFGPYLMCHAAVPMMKARGNGHIVNIASTASKRAWP
NASAYHATKWGLLGLSHALHAELRPSGVRVSAIVAGGMRTPFLLDRFPDIDEDTLQPPEHVAAAVRFVLTQPPGTVVPEL
MVLPMKETSWP
>Mature_251_residues
MQVNATHDPAKPPLAGRTALVTGGGRGLGEAICEELAQHGAHVVVADLDGDRAAAVAQRLERHGGQAVGRPLDVRDEASV
LQVVHDARESLGELDVIVNNAAIDVTAPIDDVSVDAWQQVLMTNLFGPYLMCHAAVPMMKARGNGHIVNIASTASKRAWP
NASAYHATKWGLLGLSHALHAELRPSGVRVSAIVAGGMRTPFLLDRFPDIDEDTLQPPEHVAAAVRFVLTQPPGTVVPEL
MVLPMKETSWP

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=31.5573770491803, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI19923817, Length=234, Percent_Identity=29.4871794871795, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=33.695652173913, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4503817, Length=186, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4504505, Length=187, Percent_Identity=34.2245989304813, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7657478, Length=216, Percent_Identity=31.4814814814815, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI20149619, Length=221, Percent_Identity=28.0542986425339, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI40254992, Length=227, Percent_Identity=29.9559471365639, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=32.0388349514563, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI5031737, Length=203, Percent_Identity=29.5566502463054, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=203, Percent_Identity=29.5566502463054, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=27.3092369477912, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI40254986, Length=185, Percent_Identity=31.8918918918919, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.5303643724696, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=241, Percent_Identity=31.9502074688797, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI44680136, Length=236, Percent_Identity=27.5423728813559, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI44680133, Length=236, Percent_Identity=27.5423728813559, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI17738292, Length=236, Percent_Identity=27.5423728813559, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI210032110, Length=243, Percent_Identity=21.8106995884774, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4502601, Length=154, Percent_Identity=36.3636363636364, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=29.8804780876494, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI223718074, Length=216, Percent_Identity=31.4814814814815, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI25282469, Length=273, Percent_Identity=23.4432234432234, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI142976729, Length=231, Percent_Identity=22.0779220779221, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI83715985, Length=185, Percent_Identity=30.8108108108108, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=30.9417040358744, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=172, Percent_Identity=28.4883720930233, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32455239, Length=183, Percent_Identity=29.5081967213115, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI5031765, Length=183, Percent_Identity=29.5081967213115, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542939, Length=230, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7705855, Length=226, Percent_Identity=26.5486725663717, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI310128830, Length=215, Percent_Identity=24.6511627906977, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI310115468, Length=215, Percent_Identity=24.6511627906977, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI157739938, Length=201, Percent_Identity=24.3781094527363, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI10190704, Length=184, Percent_Identity=26.6304347826087, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=36.8932038834951, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI209862901, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19923983, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4502599, Length=154, Percent_Identity=33.7662337662338, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI7706318, Length=181, Percent_Identity=26.5193370165746, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=36.3157894736842, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790717, Length=187, Percent_Identity=28.3422459893048, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789057, Length=209, Percent_Identity=31.1004784688995, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=32.4324324324324, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787820, Length=241, Percent_Identity=31.9502074688797, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789378, Length=210, Percent_Identity=29.0476190476191, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=226, Percent_Identity=28.7610619469027, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=191, Percent_Identity=28.7958115183246, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=30.8510638297872, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786701, Length=218, Percent_Identity=30.7339449541284, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367175, Length=240, Percent_Identity=30.4166666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789208, Length=210, Percent_Identity=27.1428571428571, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786812, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=220, Percent_Identity=26.3636363636364, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367365, Length=182, Percent_Identity=30.2197802197802, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=33.1578947368421, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=224, Percent_Identity=33.0357142857143, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=197, Percent_Identity=36.0406091370558, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=26.2626262626263, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=208, Percent_Identity=24.0384615384615, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17558628, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=178, Percent_Identity=33.1460674157303, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=254, Percent_Identity=25.1968503937008, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=30.0925925925926, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=31.0679611650485, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=177, Percent_Identity=26.5536723163842, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=25.4032258064516, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=168, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=222, Percent_Identity=26.5765765765766, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=222, Percent_Identity=26.5765765765766, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=198, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=201, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=263, Percent_Identity=23.9543726235741, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=29.3814432989691, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21358495, Length=248, Percent_Identity=27.0161290322581, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=27.6422764227642, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281364892, Length=177, Percent_Identity=31.638418079096, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355631, Length=241, Percent_Identity=31.1203319502075, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17737361, Length=197, Percent_Identity=30.9644670050761, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=31.9371727748691, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641232, Length=243, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24644339, Length=185, Percent_Identity=30.2702702702703, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357041, Length=204, Percent_Identity=28.4313725490196, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=203, Percent_Identity=30.5418719211823, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24639444, Length=236, Percent_Identity=29.6610169491525, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859837, Length=213, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356301, Length=239, Percent_Identity=27.1966527196653, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640492, Length=256, Percent_Identity=25, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI116007236, Length=241, Percent_Identity=29.045643153527, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643142, Length=183, Percent_Identity=30.0546448087432, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581726, Length=175, Percent_Identity=27.4285714285714, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=28.7179487179487, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=27.6, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647946, Length=207, Percent_Identity=22.7053140096618, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45553409, Length=194, Percent_Identity=23.7113402061856, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24647948, Length=194, Percent_Identity=23.7113402061856, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644337, Length=236, Percent_Identity=26.6949152542373, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221510726, Length=220, Percent_Identity=28.1818181818182, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571387, Length=246, Percent_Identity=25.609756097561, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=27.3224043715847, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=27.3224043715847, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26684; Mature: 26684

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVNATHDPAKPPLAGRTALVTGGGRGLGEAICEELAQHGAHVVVADLDGDRAAAVAQRL
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
ERHGGQAVGRPLDVRDEASVLQVVHDARESLGELDVIVNNAAIDVTAPIDDVSVDAWQQV
HHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCHHHHHHH
LMTNLFGPYLMCHAAVPMMKARGNGHIVNIASTASKRAWPNASAYHATKWGLLGLSHALH
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AELRPSGVRVSAIVAGGMRTPFLLDRFPDIDEDTLQPPEHVAAAVRFVLTQPPGTVVPEL
HCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
MVLPMKETSWP
EEECCCCCCCC
>Mature Secondary Structure
MQVNATHDPAKPPLAGRTALVTGGGRGLGEAICEELAQHGAHVVVADLDGDRAAAVAQRL
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
ERHGGQAVGRPLDVRDEASVLQVVHDARESLGELDVIVNNAAIDVTAPIDDVSVDAWQQV
HHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCHHHHHHH
LMTNLFGPYLMCHAAVPMMKARGNGHIVNIASTASKRAWPNASAYHATKWGLLGLSHALH
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AELRPSGVRVSAIVAGGMRTPFLLDRFPDIDEDTLQPPEHVAAAVRFVLTQPPGTVVPEL
HCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
MVLPMKETSWP
EEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]