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The map label for this gene is sdhB [H]

Identifier: 107022875

GI number: 107022875

Start: 1455534

End: 1456241

Strand: Reverse

Name: sdhB [H]

Synonym: Bcen_1323

Alternate gene names: 107022875

Gene position: 1456241-1455534 (Counterclockwise)

Preceding gene: 107022876

Following gene: 107022868

Centisome position: 44.2

GC content: 64.69

Gene sequence:

>708_bases
ATGAGCGATCCGCGCACCTTGCATATCTATCGCTACGACCCCGACCGCGACGCGGCGCCTTACATGCAGCGCTACGAGAT
CGACGTGAATCCGGACGACCGCATGCTGCTCGACGTGCTGGGCCGCGTGAAGTGCGACGACGAGACGCTGTCGTATCGGC
GCTCCTGCCGCGAAGGCATCTGCGGCTCGGACGCGATGAACATCAACGGCAAGAACGGCCTCGCATGCCTGACCAACATG
CAGACGCTGCCGCGCGAAATCGTGCTGCGGCCATTGCCGGGGCTGCCGGTGGTGCGCGACCTGATCGTCGACATGACCGA
TTTCTTCAACCAGTACCACTCGATCCGGCCATACCTGATCAACGACACGACGCCGCCCGCGCGCGAGCGGCTGCAATCGC
CGGAGGAGCGCGACCAGCTCGACGGGCTGTACGAATGCATCCTGTGCGCGTGCTGTTCGACGTCGTGCCCGAGCTACTGG
TGGAACCCGGACAAGTTCGTCGGTCCCGCCGGGCTGCTGCAGGCGTATCGCTTCATCGCCGATTCGCGCGATCTCGCGAC
GGCCGAGCGGCTCGACGATCTCGAGGACCCGTACCGGCTGTTCCGCTGCCGGACGATCATGAATTGCACGGACGTGTGCC
CGAAGGGGCTGAATCCGACCAAGGCGATTTCGGAGATCCGGACGATGCTGGTCAGGCGGACGGTGTGA

Upstream 100 bases:

>100_bases
ACGATTGACCGGCATCGCGCTTGCGGCGCCGTGTGCCGCGACAGCGCCCCGCCGTGCAAGTACCCCATGAACCCACGCCG
GCCCGCGCCGGGAGGAACCG

Downstream 100 bases:

>100_bases
GGCAGGATATCCCGAAGCCGGGCTTCAACTCCCGCTATTTCCCGGCGAACGCGTCCGCCTGCGCGGCGCGATGCCGTGCC
GCAACCCGATCACTGGCCGG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSDPRTLHIYRYDPDRDAAPYMQRYEIDVNPDDRMLLDVLGRVKCDDETLSYRRSCREGICGSDAMNINGKNGLACLTNM
QTLPREIVLRPLPGLPVVRDLIVDMTDFFNQYHSIRPYLINDTTPPARERLQSPEERDQLDGLYECILCACCSTSCPSYW
WNPDKFVGPAGLLQAYRFIADSRDLATAERLDDLEDPYRLFRCRTIMNCTDVCPKGLNPTKAISEIRTMLVRRTV

Sequences:

>Translated_235_residues
MSDPRTLHIYRYDPDRDAAPYMQRYEIDVNPDDRMLLDVLGRVKCDDETLSYRRSCREGICGSDAMNINGKNGLACLTNM
QTLPREIVLRPLPGLPVVRDLIVDMTDFFNQYHSIRPYLINDTTPPARERLQSPEERDQLDGLYECILCACCSTSCPSYW
WNPDKFVGPAGLLQAYRFIADSRDLATAERLDDLEDPYRLFRCRTIMNCTDVCPKGLNPTKAISEIRTMLVRRTV
>Mature_234_residues
SDPRTLHIYRYDPDRDAAPYMQRYEIDVNPDDRMLLDVLGRVKCDDETLSYRRSCREGICGSDAMNINGKNGLACLTNMQ
TLPREIVLRPLPGLPVVRDLIVDMTDFFNQYHSIRPYLINDTTPPARERLQSPEERDQLDGLYECILCACCSTSCPSYWW
NPDKFVGPAGLLQAYRFIADSRDLATAERLDDLEDPYRLFRCRTIMNCTDVCPKGLNPTKAISEIRTMLVRRTV

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=56.4655172413793, Blast_Score=268, Evalue=3e-72,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=62.3931623931624, Blast_Score=311, Evalue=2e-86,
Organism=Escherichia coli, GI1790596, Length=221, Percent_Identity=35.7466063348416, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=235, Percent_Identity=51.4893617021277, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6322987, Length=231, Percent_Identity=53.2467532467532, Blast_Score=253, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=53.6480686695279, Blast_Score=259, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=53.0172413793103, Blast_Score=246, Evalue=1e-65,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27056; Mature: 26925

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPRTLHIYRYDPDRDAAPYMQRYEIDVNPDDRMLLDVLGRVKCDDETLSYRRSCREGI
CCCCCEEEEEEECCCCCCCHHHHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCC
CGSDAMNINGKNGLACLTNMQTLPREIVLRPLPGLPVVRDLIVDMTDFFNQYHSIRPYLI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
NDTTPPARERLQSPEERDQLDGLYECILCACCSTSCPSYWWNPDKFVGPAGLLQAYRFIA
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DSRDLATAERLDDLEDPYRLFRCRTIMNCTDVCPKGLNPTKAISEIRTMLVRRTV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDPRTLHIYRYDPDRDAAPYMQRYEIDVNPDDRMLLDVLGRVKCDDETLSYRRSCREGI
CCCCEEEEEEECCCCCCCHHHHHEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCC
CGSDAMNINGKNGLACLTNMQTLPREIVLRPLPGLPVVRDLIVDMTDFFNQYHSIRPYLI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
NDTTPPARERLQSPEERDQLDGLYECILCACCSTSCPSYWWNPDKFVGPAGLLQAYRFIA
CCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DSRDLATAERLDDLEDPYRLFRCRTIMNCTDVCPKGLNPTKAISEIRTMLVRRTV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]