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The map label for this gene is nodT [H]

Identifier: 107022848

GI number: 107022848

Start: 1423580

End: 1425040

Strand: Reverse

Name: nodT [H]

Synonym: Bcen_1296

Alternate gene names: 107022848

Gene position: 1425040-1423580 (Counterclockwise)

Preceding gene: 107022853

Following gene: 107022847

Centisome position: 43.25

GC content: 70.02

Gene sequence:

>1461_bases
ATGCTACCCAAACCCATCGTTGCCGCGGCGCTGGCCGCCATCTTGTCGGCGGGGTGTGCCGTCGGTCCCGACTATGCGCG
GCCGGACGTGGCGATGCCGCGGCAGTTCCAGGGGCAGCGCGCCGTGGATCAGCGCCACGCGGCGGCCGACGCCGATCTCG
CGACGTGGTGGACGGGCTTCGGCGATCCGCAATTGACGCGCTACATCACGCTGGCGCTCGCGCAGAACCTCGATCTTGCG
CAGGCCGCGGCGCGCGTCGCGCAGGCACGCGCGGGGCTCGGCGCGGCGAATGCGGCGCTGCTGCCGTCCGGCAATGTGAG
CGGCCAGGCCGCACGCGTCTACCAGTCGGTCGAAACGCCGTTGGGGCAGGTGTTGAATGCGACGCCCGGTTTCGACCGTC
ATGGCAACGACTACGAGGCCGATTTCAACGCGAGCTGGGAGCTGGATATATTCGGCGGATTGCGCCGCGGCCGCGAAGCG
GCGCTCGCCGACTATCAGGCCTCCGAAGCGGCGGCGGTCGCGACGCGGCTCGCCGTCGCCGCGCAAACGGCGGATACCTA
CATCACGATTCGCGGGTTGCAGGGCCGGCTCGAGGTCGCGCGGCACCAGGTGCAGACCGAGCAGGATCTGCTGTCGACCC
TCAACCTGCTCTATGGAAAGGGCCTCGCGGCGGAGCTTCAGGTGCGGCAGGCCGAAGGCGCGCTCGCGCAGGTTCGTGCC
ACGGTGCCGGTGCTCGAAGCGGCGCTGGACGCGGCGATGAATGCGCTCGACGTGATGCTCGGCGCGCAGCCCGGCACACA
TCGCGCGGAATTGCTCGACGGCGGCGAGGTACCGGTCGCGCCGCGGATCGCGGCGACCGGCACGCCCGGCGAACTGCTGC
GGCGCCGGCCCGACCTGATCGCCGCCGAGCGGCGCGTGGCGGCGTCGAATGCACGCATCGGCGTGGCGATCGCCGAGTAT
TACCCGAAGTTCTCGCTGGGCGGGTTGATCGGCAGCGCGACGACGATGGGCGCGGGCAACCTGTTTGCCGGCGGCGCGAA
CCAGGCTGCGGGCGTGCTCGGCTTGCGCTGGCGTCTGTTCGATTTCGGCCGGATCAATGCGCAGATCGCGCAGGCCAAAG
GGCAGGATGCCGAAATGCTGGCTGCGTATCGGCTCGCGGCGCTGCATGCGACCGAGGACGTCGAGAATGCGTTCTCCGCG
CTCGTCAAGCGTGACGAGCAGGCGGCGATTCTCGGTGACGGCGTGAAGTCGCTCGGCCGCGCGCGGGCCGCGTCGTTCGC
GGCTTACCAGAAAGGGGTGGTCAGCCTGATCGAAGTGTTGCAGGCGGACGAAAGCCTGCTGCGCGTATCCGACGAACGCG
TGCAGGCGCGAACCGAATCGGCGCGTGCTGCGGTTGCGGCGTTCAAGGCGCTCGGCGGTGGTTGGCAGGCGCCGGAAGCG
CAGGCTGTTGCGAGTCGGTAG

Upstream 100 bases:

>100_bases
GGGGAAGGGTCGATTTTTTTCATGGGCTGCAGCTGACGGGAATGGACAACGAGTGACTATTTGGTATTATAGTCACCACC
GGATTCTTGCCAAAACCCTC

Downstream 100 bases:

>100_bases
CGGTAGTATCGGAACCTGATCGCCGCCGAACTGGGGGATTGAAGATGAAAATCAGCGAACTGGCCGAATTCGATGGCTCG
AAGTACCTGAAAGATGACGA

Product: RND efflux system, outer membrane lipoprotein, NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MLPKPIVAAALAAILSAGCAVGPDYARPDVAMPRQFQGQRAVDQRHAAADADLATWWTGFGDPQLTRYITLALAQNLDLA
QAAARVAQARAGLGAANAALLPSGNVSGQAARVYQSVETPLGQVLNATPGFDRHGNDYEADFNASWELDIFGGLRRGREA
ALADYQASEAAAVATRLAVAAQTADTYITIRGLQGRLEVARHQVQTEQDLLSTLNLLYGKGLAAELQVRQAEGALAQVRA
TVPVLEAALDAAMNALDVMLGAQPGTHRAELLDGGEVPVAPRIAATGTPGELLRRRPDLIAAERRVAASNARIGVAIAEY
YPKFSLGGLIGSATTMGAGNLFAGGANQAAGVLGLRWRLFDFGRINAQIAQAKGQDAEMLAAYRLAALHATEDVENAFSA
LVKRDEQAAILGDGVKSLGRARAASFAAYQKGVVSLIEVLQADESLLRVSDERVQARTESARAAVAAFKALGGGWQAPEA
QAVASR

Sequences:

>Translated_486_residues
MLPKPIVAAALAAILSAGCAVGPDYARPDVAMPRQFQGQRAVDQRHAAADADLATWWTGFGDPQLTRYITLALAQNLDLA
QAAARVAQARAGLGAANAALLPSGNVSGQAARVYQSVETPLGQVLNATPGFDRHGNDYEADFNASWELDIFGGLRRGREA
ALADYQASEAAAVATRLAVAAQTADTYITIRGLQGRLEVARHQVQTEQDLLSTLNLLYGKGLAAELQVRQAEGALAQVRA
TVPVLEAALDAAMNALDVMLGAQPGTHRAELLDGGEVPVAPRIAATGTPGELLRRRPDLIAAERRVAASNARIGVAIAEY
YPKFSLGGLIGSATTMGAGNLFAGGANQAAGVLGLRWRLFDFGRINAQIAQAKGQDAEMLAAYRLAALHATEDVENAFSA
LVKRDEQAAILGDGVKSLGRARAASFAAYQKGVVSLIEVLQADESLLRVSDERVQARTESARAAVAAFKALGGGWQAPEA
QAVASR
>Mature_486_residues
MLPKPIVAAALAAILSAGCAVGPDYARPDVAMPRQFQGQRAVDQRHAAADADLATWWTGFGDPQLTRYITLALAQNLDLA
QAAARVAQARAGLGAANAALLPSGNVSGQAARVYQSVETPLGQVLNATPGFDRHGNDYEADFNASWELDIFGGLRRGREA
ALADYQASEAAAVATRLAVAAQTADTYITIRGLQGRLEVARHQVQTEQDLLSTLNLLYGKGLAAELQVRQAEGALAQVRA
TVPVLEAALDAAMNALDVMLGAQPGTHRAELLDGGEVPVAPRIAATGTPGELLRRRPDLIAAERRVAASNARIGVAIAEY
YPKFSLGGLIGSATTMGAGNLFAGGANQAAGVLGLRWRLFDFGRINAQIAQAKGQDAEMLAAYRLAALHATEDVENAFSA
LVKRDEQAAILGDGVKSLGRARAASFAAYQKGVVSLIEVLQADESLLRVSDERVQARTESARAAVAAFKALGGGWQAPEA
QAVASR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=496, Percent_Identity=26.4112903225806, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI2367348, Length=492, Percent_Identity=26.4227642276423, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50829; Mature: 50829

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKPIVAAALAAILSAGCAVGPDYARPDVAMPRQFQGQRAVDQRHAAADADLATWWTGF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCC
GDPQLTRYITLALAQNLDLAQAAARVAQARAGLGAANAALLPSGNVSGQAARVYQSVETP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
LGQVLNATPGFDRHGNDYEADFNASWELDIFGGLRRGREAALADYQASEAAAVATRLAVA
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AQTADTYITIRGLQGRLEVARHQVQTEQDLLSTLNLLYGKGLAAELQVRQAEGALAQVRA
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHH
TVPVLEAALDAAMNALDVMLGAQPGTHRAELLDGGEVPVAPRIAATGTPGELLRRRPDLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCEECCCCCHHHHHCCCCHH
AAERRVAASNARIGVAIAEYYPKFSLGGLIGSATTMGAGNLFAGGANQAAGVLGLRWRLF
HHHHHHHHCCCCEEEEHHHHCCCHHHCCHHHCCHHCCCCCEECCCCCCCCHHHEEEEEEE
DFGRINAQIAQAKGQDAEMLAAYRLAALHATEDVENAFSALVKRDEQAAILGDGVKSLGR
ECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ARAASFAAYQKGVVSLIEVLQADESLLRVSDERVQARTESARAAVAAFKALGGGWQAPEA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QAVASR
HHHCCC
>Mature Secondary Structure
MLPKPIVAAALAAILSAGCAVGPDYARPDVAMPRQFQGQRAVDQRHAAADADLATWWTGF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCC
GDPQLTRYITLALAQNLDLAQAAARVAQARAGLGAANAALLPSGNVSGQAARVYQSVETP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
LGQVLNATPGFDRHGNDYEADFNASWELDIFGGLRRGREAALADYQASEAAAVATRLAVA
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AQTADTYITIRGLQGRLEVARHQVQTEQDLLSTLNLLYGKGLAAELQVRQAEGALAQVRA
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHH
TVPVLEAALDAAMNALDVMLGAQPGTHRAELLDGGEVPVAPRIAATGTPGELLRRRPDLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCEECCCCCHHHHHCCCCHH
AAERRVAASNARIGVAIAEYYPKFSLGGLIGSATTMGAGNLFAGGANQAAGVLGLRWRLF
HHHHHHHHCCCCEEEEHHHHCCCHHHCCHHHCCHHCCCCCEECCCCCCCCHHHEEEEEEE
DFGRINAQIAQAKGQDAEMLAAYRLAALHATEDVENAFSALVKRDEQAAILGDGVKSLGR
ECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ARAASFAAYQKGVVSLIEVLQADESLLRVSDERVQARTESARAAVAAFKALGGGWQAPEA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QAVASR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]