Click here to switch to the map view.

The map label for this gene is emrK [H]

Identifier: 107022835

GI number: 107022835

Start: 1409352

End: 1410779

Strand: Reverse

Name: emrK [H]

Synonym: Bcen_1283

Alternate gene names: 107022835

Gene position: 1410779-1409352 (Counterclockwise)

Preceding gene: 107022838

Following gene: 107022834

Centisome position: 42.82

GC content: 72.27

Gene sequence:

>1428_bases
ATGCCCGATGCGATCCTGTGCCCGTTGTCCGTTCGTGAGCGATGGTGCGTCGCGGTCCGGCGCGCGTTGACGCCCGGACC
GCGACGCACCGGCGCGCCGGACGCGTTCGCGCCGGCGGTGGCCGGTGTCGCCCTGTCGACGCCGATGAGGCCGATGGCGC
CGATGCGCGTGCCTTGGCCGGCGTTAGCGCCTGCGTTCCAGCGCTGGTCCACCGCCATCGCCCGTGCAGGCGACGGCCAG
TCCGGCGGCGGCAGCGGCTCGGGCGCCGCGCCAGGCCGCAACGGCGAGCACTCGACCGACGCGCCGGGCGGCGGTGGCGG
CGACGACCATCCGCACGACGACCGCGGCGGCCGCACCGGCGGCGACGGGGATGGCAACGACGGCGAACGCAAGCGGCCCG
GCAAGAAGCCGCTGATCATCCTGGGCGCGGTGGTGTTGGTGCTGCTCATCGGCGGGCTCGTGTGGTGGTTCGCGACGCGC
AACCAGGAAAGCACCGACGATGCGTATACCGACGGCAACGCGATCGCGGTCGCGCCGCACGTGTCCGGCTACGTGACGCG
CCTGGCGGTCGACGACAACACCTTCGTGCGGCGCGGCGACGTGCTCGTCGAGATCGATCCGCGCGACTACCGCGCGCAGG
TCGACGCGGCGCAGGCCCAGCTCGGTCTCGCGCAGGCGCAGCTCGACGCGGCGCGCGTGCAGCTCGATATCGCGCGCGTG
CAGTATCCGGCCCAGTACCGGCAGGCGCGCGCGCAGATCGAATCGGCGGAAGCCGCGTACCGGCAGGCGCTCGCCGCGCA
GTCCCGCCAGCGGGCGGTCGATGCGCGCGCAACCTCGCAGCAGGCGATCGACGCGGCCGATGCGCAGCGCGCGACCGCCG
ACGCGAACGTCGCGATGGCCCAGGCGCAGGCCCGCACCGCGAGCCTCGTGCCGCAGCAGATCCGGCAGGCCGAGACCGCC
GTCGAGGAACGCCGCCAGCAGGTGCTGCAGGCACGCGCGCAGCTCGAGACGGCCAACCTGAACCTGTCGTACTGCGAGAT
GCGCGCGCCGTCCGACGGCTGGGTCACGCGGCGCAACGTGCAACTGGGCTCGTTCCTGCAACCGGGCACGTCGATCTTCT
CGATCGTCACGCCGCGCGTGTGGGTCACCGCGAATTTCAAGGAGTCGCAGCTCGAGCGGATGCGCATCGGCGACCGCGTC
GACGTGTCGGTCGACGCGTATCCCGATCTCGACCTGCACGGCCACGTCGACAGCATCCAGCTCGGCAGCGGCTCGCGTTT
CTCCGCGTTCCCGACCGAGAACGCGACTGGCAACTTCGTGAAGATCGTGCAGCGCGTGCCGGTGAAGATCGTGCTCGACG
GCCCGCTGCCGACCCGTCCACCGCTCGGTCTCGGCCTGTCGGCCGTGCCGACCGTTCACCTCAAATGA

Upstream 100 bases:

>100_bases
GGTCGGACGAAGCAGGTGGCCGGGCCCGCCGTTTGCTTGATCGCGCGCTTGAGGTCGGCGCGAGCAATGTCGCCCGCGCC
GCCGCCTGGAGCCCCGTTTC

Downstream 100 bases:

>100_bases
CCGGCCGCCGTGCCGCGGCCGGTGCCGACCGGAGCGATCCGATGCCCGATACCCGCATGCCGTTCCCGTTTCGCGAGGCC
CGCCGATGAGCCGGCCGCCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MPDAILCPLSVRERWCVAVRRALTPGPRRTGAPDAFAPAVAGVALSTPMRPMAPMRVPWPALAPAFQRWSTAIARAGDGQ
SGGGSGSGAAPGRNGEHSTDAPGGGGGDDHPHDDRGGRTGGDGDGNDGERKRPGKKPLIILGAVVLVLLIGGLVWWFATR
NQESTDDAYTDGNAIAVAPHVSGYVTRLAVDDNTFVRRGDVLVEIDPRDYRAQVDAAQAQLGLAQAQLDAARVQLDIARV
QYPAQYRQARAQIESAEAAYRQALAAQSRQRAVDARATSQQAIDAADAQRATADANVAMAQAQARTASLVPQQIRQAETA
VEERRQQVLQARAQLETANLNLSYCEMRAPSDGWVTRRNVQLGSFLQPGTSIFSIVTPRVWVTANFKESQLERMRIGDRV
DVSVDAYPDLDLHGHVDSIQLGSGSRFSAFPTENATGNFVKIVQRVPVKIVLDGPLPTRPPLGLGLSAVPTVHLK

Sequences:

>Translated_475_residues
MPDAILCPLSVRERWCVAVRRALTPGPRRTGAPDAFAPAVAGVALSTPMRPMAPMRVPWPALAPAFQRWSTAIARAGDGQ
SGGGSGSGAAPGRNGEHSTDAPGGGGGDDHPHDDRGGRTGGDGDGNDGERKRPGKKPLIILGAVVLVLLIGGLVWWFATR
NQESTDDAYTDGNAIAVAPHVSGYVTRLAVDDNTFVRRGDVLVEIDPRDYRAQVDAAQAQLGLAQAQLDAARVQLDIARV
QYPAQYRQARAQIESAEAAYRQALAAQSRQRAVDARATSQQAIDAADAQRATADANVAMAQAQARTASLVPQQIRQAETA
VEERRQQVLQARAQLETANLNLSYCEMRAPSDGWVTRRNVQLGSFLQPGTSIFSIVTPRVWVTANFKESQLERMRIGDRV
DVSVDAYPDLDLHGHVDSIQLGSGSRFSAFPTENATGNFVKIVQRVPVKIVLDGPLPTRPPLGLGLSAVPTVHLK
>Mature_474_residues
PDAILCPLSVRERWCVAVRRALTPGPRRTGAPDAFAPAVAGVALSTPMRPMAPMRVPWPALAPAFQRWSTAIARAGDGQS
GGGSGSGAAPGRNGEHSTDAPGGGGGDDHPHDDRGGRTGGDGDGNDGERKRPGKKPLIILGAVVLVLLIGGLVWWFATRN
QESTDDAYTDGNAIAVAPHVSGYVTRLAVDDNTFVRRGDVLVEIDPRDYRAQVDAAQAQLGLAQAQLDAARVQLDIARVQ
YPAQYRQARAQIESAEAAYRQALAAQSRQRAVDARATSQQAIDAADAQRATADANVAMAQAQARTASLVPQQIRQAETAV
EERRQQVLQARAQLETANLNLSYCEMRAPSDGWVTRRNVQLGSFLQPGTSIFSIVTPRVWVTANFKESQLERMRIGDRVD
VSVDAYPDLDLHGHVDSIQLGSGSRFSAFPTENATGNFVKIVQRVPVKIVLDGPLPTRPPLGLGLSAVPTVHLK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=358, Percent_Identity=31.5642458100559, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789041, Length=353, Percent_Identity=33.4277620396601, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1790519, Length=319, Percent_Identity=31.3479623824451, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1789637, Length=336, Percent_Identity=27.6785714285714, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790024, Length=279, Percent_Identity=30.8243727598566, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87081951, Length=323, Percent_Identity=27.8637770897833, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790012, Length=279, Percent_Identity=27.2401433691756, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787013, Length=298, Percent_Identity=29.5302013422819, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50749; Mature: 50617

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAILCPLSVRERWCVAVRRALTPGPRRTGAPDAFAPAVAGVALSTPMRPMAPMRVPWP
CCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
ALAPAFQRWSTAIARAGDGQSGGGSGSGAAPGRNGEHSTDAPGGGGGDDHPHDDRGGRTG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDGDGNDGERKRPGKKPLIILGAVVLVLLIGGLVWWFATRNQESTDDAYTDGNAIAVAPH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCC
VSGYVTRLAVDDNTFVRRGDVLVEIDPRDYRAQVDAAQAQLGLAQAQLDAARVQLDIARV
CCCEEEEEEECCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHH
QYPAQYRQARAQIESAEAAYRQALAAQSRQRAVDARATSQQAIDAADAQRATADANVAMA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QAQARTASLVPQQIRQAETAVEERRQQVLQARAQLETANLNLSYCEMRAPSDGWVTRRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECC
QLGSFLQPGTSIFSIVTPRVWVTANFKESQLERMRIGDRVDVSVDAYPDLDLHGHVDSIQ
CCCCCCCCCHHHHHEECCEEEEEECCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEE
LGSGSRFSAFPTENATGNFVKIVQRVPVKIVLDGPLPTRPPLGLGLSAVPTVHLK
ECCCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure 
PDAILCPLSVRERWCVAVRRALTPGPRRTGAPDAFAPAVAGVALSTPMRPMAPMRVPWP
CCCEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCH
ALAPAFQRWSTAIARAGDGQSGGGSGSGAAPGRNGEHSTDAPGGGGGDDHPHDDRGGRTG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDGDGNDGERKRPGKKPLIILGAVVLVLLIGGLVWWFATRNQESTDDAYTDGNAIAVAPH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCC
VSGYVTRLAVDDNTFVRRGDVLVEIDPRDYRAQVDAAQAQLGLAQAQLDAARVQLDIARV
CCCEEEEEEECCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHH
QYPAQYRQARAQIESAEAAYRQALAAQSRQRAVDARATSQQAIDAADAQRATADANVAMA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QAQARTASLVPQQIRQAETAVEERRQQVLQARAQLETANLNLSYCEMRAPSDGWVTRRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECC
QLGSFLQPGTSIFSIVTPRVWVTANFKESQLERMRIGDRVDVSVDAYPDLDLHGHVDSIQ
CCCCCCCCCHHHHHEECCEEEEEECCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEE
LGSGSRFSAFPTENATGNFVKIVQRVPVKIVLDGPLPTRPPLGLGLSAVPTVHLK
ECCCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]