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The map label for this gene is yisK [H]

Identifier: 107022784

GI number: 107022784

Start: 1356181

End: 1357062

Strand: Reverse

Name: yisK [H]

Synonym: Bcen_1231

Alternate gene names: 107022784

Gene position: 1357062-1356181 (Counterclockwise)

Preceding gene: 107022788

Following gene: 107022783

Centisome position: 41.19

GC content: 57.03

Gene sequence:

>882_bases
ATGAAGCTGGCTAACCTTAATGTGGCGGGAAAGAAGACAATTTCGATTGTGGATATCGTTCATTCTCGATTCTGGCCGGT
CCAATCGTTGGTCCCCCAATTTGACGGCGATATGGTCCAATTGGTCCAACAATTTGAAGAAGTCAAACCGCATCTGAAGC
CAACGGGGAACGGTTTGTCGCTCGCGGAGGCCACCATCTTGGCCCCGATCGATCAGCCGCGTCGCAACATCTTCTGTGTC
GGCAAGAACTATCACGAGCATGCGGCCGAGTTCCAGAACTCGGGATTCGACAGCAGCGCAAAGAACGGCGAGCACGCGCC
GGAGGCGCCGGTCATTTTCACCAAGCCGGCGTCGACGGTGATCGGGCCGTCGGCAAAGATCCCACGACATGTCGGCGTGA
CCGCTCAGCTCGACTACGAGGCCGAGCTGGGTGTCGTGATCGGCAAGGGCGGCCGGGGTATCAAGAAGGCGGACGCAATG
AATTACGTCTTCGGCTACACCGTGATCAACGACTTCACCGCTCGGGATCTTCAGAAGCTTCACCGCCAGTGGTTCCTCGG
AAAGTCGCTCGACGGCTTCTGTCCGATGGGGCCGTTCGTGATCACGTCGGACGAAGTCAACGGCCAGAACATCGACATCA
AGTGTTGGGTGAACGGCGAATTGCGTCAGAACTCCAACACGTCCAAGCTGATCTTTGATATCCCGACGCTGATCGAAACC
CTGTCGGCCGGCATCGAACTTCAGCCGGGTGATGTGATTGCGACCGGTACCCCGGCCGGCGTCGGTATCGGCTTCAATCC
ACCCAAATTCCTGCAGAAGGGTGATGTGATCCGAATCGAGATCCAGAACGTCGGTGTACTCGAGAATGAGGTGGGCGAAT
GA

Upstream 100 bases:

>100_bases
TTGGACAGGATTTTGGTTTACCCGTACTTGCGTTCGGTCCACTTTGGTTCTACAGTGCGAGCACTTTCAACCAATTGGAC
TCGCGAACAGGAGTGATCTC

Downstream 100 bases:

>100_bases
CGACGACCCTCATCAGAGATATTGCCGTCGAGATAACCGGGGAAGGTCAGCCCGTCGTGTGCATCCACGGACTCGGTGGC
TCCTCGAACAACTGGACCCC

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKLANLNVAGKKTISIVDIVHSRFWPVQSLVPQFDGDMVQLVQQFEEVKPHLKPTGNGLSLAEATILAPIDQPRRNIFCV
GKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAM
NYVFGYTVINDFTARDLQKLHRQWFLGKSLDGFCPMGPFVITSDEVNGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIET
LSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE

Sequences:

>Translated_293_residues
MKLANLNVAGKKTISIVDIVHSRFWPVQSLVPQFDGDMVQLVQQFEEVKPHLKPTGNGLSLAEATILAPIDQPRRNIFCV
GKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAM
NYVFGYTVINDFTARDLQKLHRQWFLGKSLDGFCPMGPFVITSDEVNGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIET
LSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE
>Mature_293_residues
MKLANLNVAGKKTISIVDIVHSRFWPVQSLVPQFDGDMVQLVQQFEEVKPHLKPTGNGLSLAEATILAPIDQPRRNIFCV
GKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTVIGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAM
NYVFGYTVINDFTARDLQKLHRQWFLGKSLDGFCPMGPFVITSDEVNGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIET
LSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=239, Percent_Identity=43.0962343096234, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI40786394, Length=239, Percent_Identity=43.0962343096234, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI215422413, Length=192, Percent_Identity=39.5833333333333, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI13654274, Length=192, Percent_Identity=39.5833333333333, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI66348062, Length=192, Percent_Identity=39.5833333333333, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI1787428, Length=220, Percent_Identity=34.0909090909091, Blast_Score=101, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17557057, Length=189, Percent_Identity=42.3280423280423, Blast_Score=141, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324161, Length=246, Percent_Identity=28.8617886178862, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28572127, Length=232, Percent_Identity=41.8103448275862, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24663695, Length=294, Percent_Identity=34.0136054421769, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28571789, Length=191, Percent_Identity=34.5549738219895, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 31856; Mature: 31856

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLANLNVAGKKTISIVDIVHSRFWPVQSLVPQFDGDMVQLVQQFEEVKPHLKPTGNGLS
CEEECCCCCCCCEEHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
LAEATILAPIDQPRRNIFCVGKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTV
EEHEEEECCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
IGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAMNYVFGYTVINDFTARDLQKL
CCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHEEEEEHHHCCHHHHHHHHH
HRQWFLGKSLDGFCPMGPFVITSDEVNGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIET
HHHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCEEECCCCCCEEEEEHHHHHHH
LSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE
HHCCCEECCCCEEEECCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MKLANLNVAGKKTISIVDIVHSRFWPVQSLVPQFDGDMVQLVQQFEEVKPHLKPTGNGLS
CEEECCCCCCCCEEHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
LAEATILAPIDQPRRNIFCVGKNYHEHAAEFQNSGFDSSAKNGEHAPEAPVIFTKPASTV
EEHEEEECCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
IGPSAKIPRHVGVTAQLDYEAELGVVIGKGGRGIKKADAMNYVFGYTVINDFTARDLQKL
CCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHEEEEEHHHCCHHHHHHHHH
HRQWFLGKSLDGFCPMGPFVITSDEVNGQNIDIKCWVNGELRQNSNTSKLIFDIPTLIET
HHHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCEEECCCCCCEEEEEHHHHHHH
LSAGIELQPGDVIATGTPAGVGIGFNPPKFLQKGDVIRIEIQNVGVLENEVGE
HHCCCEECCCCEEEECCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]