| Definition | Burkholderia cenocepacia AU 1054 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008060 |
| Length | 3,294,563 |
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The map label for this gene is cobB [H]
Identifier: 107022724
GI number: 107022724
Start: 1288827
End: 1290236
Strand: Reverse
Name: cobB [H]
Synonym: Bcen_1171
Alternate gene names: 107022724
Gene position: 1290236-1288827 (Counterclockwise)
Preceding gene: 107022725
Following gene: 107022721
Centisome position: 39.16
GC content: 69.65
Gene sequence:
>1410_bases ATGCCGGCCTGCCCCGCGCTGTTCGTCAGCGCGCCCGCGTCCGGCCAGGGCAAGACGTCGGTCACGGTCGGTCTCGCGCG GCTGCACCGGCGGCTCGGCCGCCGCGTGCGCGTGTTCAAGACCGGGCCCGATTTTCTCGATCCGATGCTGCTCGAACGCG CGAGCGGCGCACCCGTGCACGCGCTCGACCTCGGGATGGTCGGCGAGGCCGGTTGCCGCGCGCTGCTCGCCGAAGCCGCG CGCGACGCGGACCTGATCCTGATCGAAGGCGTGATGGGCTTGTTCGACGGCACGCCGAGCAGCGCCGATCTCGCGGCCGC GTTCGGCGCGCCGGTCGTCGCGGTGATTTCGGCGAAGGCGATGGCGCAGACGTTCGCGGCGATCGCGTTCGGGCTCGCGC GGTTTCGGCCGGGGTTGCCGTTTCACGGCGTGCTGGCCAACCGCGTCGGCTCGGCACGGCACGCGGAATTGCTGCAACAG GCGTTGCCCGACGATCTTCGCTGGCTCGGCCACGTGCCGGCCGATGCGGGTATCGCGCTGCCGGAGCGGCATCTCGGCCT GCATCAGCCGGCCGATATCGACGATCTCGACGCGCGGCTCGATCGCGCGGCCGATGTGCTCGCGCAGACGGCACTGGCCG AATTGCCGCCGGCCGTCGCGTTCGCGGAGCCGGACGTTGCCGCGCCGTTGCCGCGCGCGCTTGCCGGCAAGCGGATCGCG GTGGCGCGCGATGCGGCGTTTTCGTTCATCTATCCGGCGAATCTCGCGTTGCTGGGCGCGCTCGGTGCGCAGTTGCGGTT CTTTTCGCCGCTTGCCGACGAACCCGTGCCTGACGATTGCGACGCGCTGTTTTTGCCGGGCGGCTATCCGGAACTGCATG CGGCGACGCTGGCCGCGAATGCCGCGACCGCACGGACGATTCGCGCGCATGCGGCAGCCGGCCGGCCGATCGTCGCGGAA TGCGGGGGGGATGGTGTATCTGTGCGAATCGCTGACCGACGTGGATGGGTCGACGACACCGATGCTCGGCCTGCTGCCGG GGCATGCGACGATGCAACGCCGGTTCGCGGCGCTCGGCATGCAGCAGCTCGATACTGGCACGGGACCGATGCGCGGTCAT ACGTTTCATTATTCGCGGCTGGATACGCCGCTCGTGCCGGTCGCGACCGCCGCGCGGCCCGATGGCTCGGAGGGCGGCGG CGAAGCCGTTTATCGCGTGGGCGCGATCGTCGCGACGTACATGCACATGTACTGGCCGTCGAATCCGGATCTGGTCGTGG CTTTGTTCGGTGGGGAAGTGTTCGAGACATGAGCGGCCAGCTTGCCGAGCGGCCGACCTTCGACGGTACGACGCCAACGA TCTTCAGGATTCGGGGCAGGAATCGCGTGACCAGACGTGACCGGCCTTAG
Upstream 100 bases:
>100_bases CGCTGATCGATGCGGCCGATCTCGTCACCGAAATGCGGCTCGTCAAGCATCCGTACAAGGAGCAAGGCGTGAAGGCGCAG CGCGGCGTGGAGTTCTGAGC
Downstream 100 bases:
>100_bases CCGCAACGCGTTGCGCCCGCATGCGGGCCAGGAAGGTTTCTCCGTCGAACGTATTGGGATGACCTGAGGCCTCCCCGGCG TCCAGCGCGTCCTGCAACGC
Product: cobyrinic acid a,c-diamide synthase
Products: ADP; phosphate; Hydrogenobyrinic acid a,c diamide; L-glutamate
Alternate protein names: NA
Number of amino acids: Translated: 469; Mature: 468
Protein sequence:
>469_residues MPACPALFVSAPASGQGKTSVTVGLARLHRRLGRRVRVFKTGPDFLDPMLLERASGAPVHALDLGMVGEAGCRALLAEAA RDADLILIEGVMGLFDGTPSSADLAAAFGAPVVAVISAKAMAQTFAAIAFGLARFRPGLPFHGVLANRVGSARHAELLQQ ALPDDLRWLGHVPADAGIALPERHLGLHQPADIDDLDARLDRAADVLAQTALAELPPAVAFAEPDVAAPLPRALAGKRIA VARDAAFSFIYPANLALLGALGAQLRFFSPLADEPVPDDCDALFLPGGYPELHAATLAANAATARTIRAHAAAGRPIVAE CGGDGVSVRIADRRGWVDDTDARPAAGACDDATPVRGARHAAARYWHGTDARSYVSLFAAGYAARAGRDRRAARWLGGRR RSRLSRGRDRRDVHAHVLAVESGSGRGFVRWGSVRDMSGQLAERPTFDGTTPTIFRIRGRNRVTRRDRP
Sequences:
>Translated_469_residues MPACPALFVSAPASGQGKTSVTVGLARLHRRLGRRVRVFKTGPDFLDPMLLERASGAPVHALDLGMVGEAGCRALLAEAA RDADLILIEGVMGLFDGTPSSADLAAAFGAPVVAVISAKAMAQTFAAIAFGLARFRPGLPFHGVLANRVGSARHAELLQQ ALPDDLRWLGHVPADAGIALPERHLGLHQPADIDDLDARLDRAADVLAQTALAELPPAVAFAEPDVAAPLPRALAGKRIA VARDAAFSFIYPANLALLGALGAQLRFFSPLADEPVPDDCDALFLPGGYPELHAATLAANAATARTIRAHAAAGRPIVAE CGGDGVSVRIADRRGWVDDTDARPAAGACDDATPVRGARHAAARYWHGTDARSYVSLFAAGYAARAGRDRRAARWLGGRR RSRLSRGRDRRDVHAHVLAVESGSGRGFVRWGSVRDMSGQLAERPTFDGTTPTIFRIRGRNRVTRRDRP >Mature_468_residues PACPALFVSAPASGQGKTSVTVGLARLHRRLGRRVRVFKTGPDFLDPMLLERASGAPVHALDLGMVGEAGCRALLAEAAR DADLILIEGVMGLFDGTPSSADLAAAFGAPVVAVISAKAMAQTFAAIAFGLARFRPGLPFHGVLANRVGSARHAELLQQA LPDDLRWLGHVPADAGIALPERHLGLHQPADIDDLDARLDRAADVLAQTALAELPPAVAFAEPDVAAPLPRALAGKRIAV ARDAAFSFIYPANLALLGALGAQLRFFSPLADEPVPDDCDALFLPGGYPELHAATLAANAATARTIRAHAAAGRPIVAEC GGDGVSVRIADRRGWVDDTDARPAAGACDDATPVRGARHAAARYWHGTDARSYVSLFAAGYAARAGRDRRAARWLGGRRR SRLSRGRDRRDVHAHVLAVESGSGRGFVRWGSVRDMSGQLAERPTFDGTTPTIFRIRGRNRVTRRDRP
Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]
COG id: COG1797
COG function: function code H; Cobyrinic acid a,c-diamide synthase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 GATase cobBQ-type domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002586 - InterPro: IPR004484 - InterPro: IPR017929 - InterPro: IPR011698 [H]
Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]
EC number: 6.3.5.9
Molecular weight: Translated: 49605; Mature: 49474
Theoretical pI: Translated: 10.43; Mature: 10.43
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPACPALFVSAPASGQGKTSVTVGLARLHRRLGRRVRVFKTGPDFLDPMLLERASGAPVH CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEE ALDLGMVGEAGCRALLAEAARDADLILIEGVMGLFDGTPSSADLAAAFGAPVVAVISAKA EEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHH MAQTFAAIAFGLARFRPGLPFHGVLANRVGSARHAELLQQALPDDLRWLGHVPADAGIAL HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCC PERHLGLHQPADIDDLDARLDRAADVLAQTALAELPPAVAFAEPDVAAPLPRALAGKRIA CHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHCCCEEE VARDAAFSFIYPANLALLGALGAQLRFFSPLADEPVPDDCDALFLPGGYPELHAATLAAN EEHHCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHC AATARTIRAHAAAGRPIVAECGGDGVSVRIADRRGWVDDTDARPAAGACDDATPVRGARH HHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH AAARYWHGTDARSYVSLFAAGYAARAGRDRRAARWLGGRRRSRLSRGRDRRDVHAHVLAV HHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE ESGSGRGFVRWGSVRDMSGQLAERPTFDGTTPTIFRIRGRNRVTRRDRP ECCCCCEEEEECCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCC >Mature Secondary Structure PACPALFVSAPASGQGKTSVTVGLARLHRRLGRRVRVFKTGPDFLDPMLLERASGAPVH CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCCEE ALDLGMVGEAGCRALLAEAARDADLILIEGVMGLFDGTPSSADLAAAFGAPVVAVISAKA EEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHH MAQTFAAIAFGLARFRPGLPFHGVLANRVGSARHAELLQQALPDDLRWLGHVPADAGIAL HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCC PERHLGLHQPADIDDLDARLDRAADVLAQTALAELPPAVAFAEPDVAAPLPRALAGKRIA CHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHCCCEEE VARDAAFSFIYPANLALLGALGAQLRFFSPLADEPVPDDCDALFLPGGYPELHAATLAAN EEHHCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHC AATARTIRAHAAAGRPIVAECGGDGVSVRIADRRGWVDDTDARPAAGACDDATPVRGARH HHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH AAARYWHGTDARSYVSLFAAGYAARAGRDRRAARWLGGRRRSRLSRGRDRRDVHAHVLAV HHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE ESGSGRGFVRWGSVRDMSGQLAERPTFDGTTPTIFRIRGRNRVTRRDRP ECCCCCEEEEECCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; hydrogenobyrinic acid; L-glutamine; H2O
Specific reaction: 2 ATP + hydrogenobyrinic acid + 2 L-glutamine + 2 H2O = 2 ADP + 2 phosphate + hydrogenobyrinic acid a,c-diamide + 2 L-glutamate
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA