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The map label for this gene is livM [H]

Identifier: 107021987

GI number: 107021987

Start: 472250

End: 473437

Strand: Reverse

Name: livM [H]

Synonym: Bcen_0429

Alternate gene names: 107021987

Gene position: 473437-472250 (Counterclockwise)

Preceding gene: 107021988

Following gene: 107021986

Centisome position: 14.37

GC content: 68.1

Gene sequence:

>1188_bases
GTGACTTCATACACCGATTCGATGTCGAACCCGGTCGCCGACGCGTCGAAGCCCGCTGCCGCCGCGCGCGCGGCGGACGG
CTTCGCGCTCGGCCTGCCGCCCCGCCCCGCGCTGCTGTCGCGCCGCGCGTGGCTCGCGCTCGTCGCGCTGTGCGTGGCGA
TCGGCATCGGCGTGCCGCTCGCCGCGCTGGTTGCGCCCGAAGCCAGCGCGTTCCATCTGTCCGCGTACACGATGACGCTC
GCCGGCAAGCTGATGTGCTACGCGATCGCCGCGCTCGCGCTCGATCTCGTGTGGGGCTACTGCGGCATCCTGAGCCTCGG
CCACGGCCTGTTCTTCGCGCTCGGCGGCTATGCGATCGGCATGTACCTGATGCGCGAGATCGGCCGCGACGGCAAGTACG
GCAGCGACCTGCCCGACTTCATGGTGTTTCTCGACTGGCACCAGTTGCCGTGGTACTGGAGCGGCACGCAGCATCTCGCG
TGGGCCCTCGCGCTGGTCGTGCTCGTGCCGGCCGTGCTCGCGTGGGTGTTCGGCTTCTTCACGTTCCGCTCGCGCGTGAA
GGGCGTGTACCTGTCGATCATCACGCAGGCCATGACGTTCGCCGCGATGCTGCTGTTCTATCGCAACGAGACGGGCTTCG
GCGGCAACAACGGCTTCACCGATTTCAAGCGCATCGCCGGCTTCGCGATCACGTCGCCGGGCACGCGTACGGTGCTGTTG
CTGCTGACGTTCGCGATCCTCGTGCTCGCGTTCATCGCCGCGCGCGCGATCGTCACGAGCAAGCTCGGGCGCGTGGTGAC
CGCGGTGCGCGACGGCGAGACGCGGCTGATGTTCCTCGGCTACAGCCCGCTCGCGTACAAGCTGTTCGTGTGGACCGTGT
CGGCCGTGCTGTGCGGCATCGCCGGCGCGCTGTACGTGCCGCAGGTCGGCATCATCAATCCCGGCGAGATGTCGCCCGGC
AACTCGATCGAAATGGCGATCTGGGTCGCGGTGGGCGGGCGCGGCACGCTGATCGGGCCGATCGTCGGCGCGTTCGCGGT
GAACGGCGCGAAGAGTTTCTTCACCGCGTACTTCGCCGAATACTGGCTGTTCTTCCTCGGCCTGATCTTCGTGCTCGTGC
CGCTCCTGCTGCCGCGCGGGATCATGGGCCTCGTCGAAACCGTGCTCGCGAAGGGGAAACGCGCATGA

Upstream 100 bases:

>100_bases
GTACTCGCGAAGATCGCGGTGCTCGTGATGATCGTGCTGTTCATCCAGAAACGCCCGCAGGGGATGTTCGCCCCGAAGGG
CCGCAGCGCGGAGGCTTGAC

Downstream 100 bases:

>100_bases
ACGGAACGGCTCTCTACCAGTTCACGCCGCCGCCCGAGGACGAGCTGCTGGCCGTCAGCGGCAGCGCATCGATGGGGCGC
GTCGTGCCGGACGGCATCGA

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTSYTDSMSNPVADASKPAAAARAADGFALGLPPRPALLSRRAWLALVALCVAIGIGVPLAALVAPEASAFHLSAYTMTL
AGKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMREIGRDGKYGSDLPDFMVFLDWHQLPWYWSGTQHLA
WALALVVLVPAVLAWVFGFFTFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPGTRTVLL
LLTFAILVLAFIAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGALYVPQVGIINPGEMSPG
NSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSFFTAYFAEYWLFFLGLIFVLVPLLLPRGIMGLVETVLAKGKRA

Sequences:

>Translated_395_residues
MTSYTDSMSNPVADASKPAAAARAADGFALGLPPRPALLSRRAWLALVALCVAIGIGVPLAALVAPEASAFHLSAYTMTL
AGKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMREIGRDGKYGSDLPDFMVFLDWHQLPWYWSGTQHLA
WALALVVLVPAVLAWVFGFFTFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPGTRTVLL
LLTFAILVLAFIAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGALYVPQVGIINPGEMSPG
NSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSFFTAYFAEYWLFFLGLIFVLVPLLLPRGIMGLVETVLAKGKRA
>Mature_394_residues
TSYTDSMSNPVADASKPAAAARAADGFALGLPPRPALLSRRAWLALVALCVAIGIGVPLAALVAPEASAFHLSAYTMTLA
GKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMREIGRDGKYGSDLPDFMVFLDWHQLPWYWSGTQHLAW
ALALVVLVPAVLAWVFGFFTFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPGTRTVLLL
LTFAILVLAFIAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGALYVPQVGIINPGEMSPGN
SIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSFFTAYFAEYWLFFLGLIFVLVPLLLPRGIMGLVETVLAKGKRA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=353, Percent_Identity=25.7790368271955, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 42331; Mature: 42200

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYTDSMSNPVADASKPAAAARAADGFALGLPPRPALLSRRAWLALVALCVAIGIGVPL
CCCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHH
AALVAPEASAFHLSAYTMTLAGKLMCYAIAALALDLVWGYCGILSLGHGLFFALGGYAIG
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYLMREIGRDGKYGSDLPDFMVFLDWHQLPWYWSGTQHLAWALALVVLVPAVLAWVFGFF
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHH
TFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFAITSPGTRTVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCEEECCCCHHHHHH
LLTFAILVLAFIAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHH
AGALYVPQVGIINPGEMSPGNSIEMAIWVAVGGRGTLIGPIVGAFAVNGAKSFFTAYFAE
HHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHH
YWLFFLGLIFVLVPLLLPRGIMGLVETVLAKGKRA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSYTDSMSNPVADASKPAAAARAADGFALGLPPRPALLSRRAWLALVALCVAIGIGVPL
CCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHH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HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]