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The map label for this gene is cmcT [H]

Identifier: 107021920

GI number: 107021920

Start: 403607

End: 405046

Strand: Reverse

Name: cmcT [H]

Synonym: Bcen_0362

Alternate gene names: 107021920

Gene position: 405046-403607 (Counterclockwise)

Preceding gene: 107021921

Following gene: 107021919

Centisome position: 12.29

GC content: 70.83

Gene sequence:

>1440_bases
ATGACCCACGGGATTCACGGCGAGAAGCGCTGGTACGCGCTGATCGTGCTCTGTCTCGGCGTGCTGATGATCGTGCTCGA
CAGCACGATCGTGAACGTTGCGCTGCCGTCGATCAGTACCGACCTCCACTTCACCGAAACGGCCCTCGTCTGGGTCGTCA
ACGCGTACCTGCTGACGTTCGGCGGCTGCCTGCTGCTCGGCGGCCGGCTCGGCGACCTGTACGGCCAGCGGCGCATGTTC
CTCGCGGGCCTCGTCGTGTTCACGCTCGCGTCGCTCGCCTGCGGCCTCGCGCAATCGCAGGCGATGCTGATCGCCGCGCG
CGCGGTGCAGGGACTCGGCGGCGCGGTCGTGTCGGCCGTCTCGCTGTCGCTGATCATGAATCTCTTCACGGAACCCGGCG
AACGCGCGCGTGCGATGGGCGTCTACGGCTTCGTCTGCGCGGGCGGCGGCAGCATCGGCGTGCTGCTCGGCGGGCTGCTG
ACGAGCTCGCTGTCGTGGCACTGGATCTTCCTCGTCAACCTGCCGATCGGCGTCGCCGTCTATGCGATGTGCGTCGCGTT
GCTGCCGCGCGTGCGTGCACCGGCCGGCACCGCGCGGCTCGACGTCGCCGGCGCGATCACGGTGACCGCATCGCTGATGC
TGGCCGTCTACGGGATCGTCGGCGGCAACGAGGCCGGCTGGCTGTCGACGCAGACCGTCGCACTGATCGGCGCGGCCGTC
GTGCTGCTCGCGCTGTTCATCGCGATCGAGTCGCGTGCCGCGCATCCGCTGATGCCGCTCACGCTGTTCGCCGCGCGCAA
CGTGGCGCTCGCGAATGCGATCGCCGTGCTGTGGGCAGCCGCGATGTTCGCGTGGTTCTTCCTGTCCGCGCTGTACATGC
AGCGCGTGCTCGGCTATGGGCCGCTGCAGGTCGGCCTCGCGTTCCTGCCGGCGAATTTGATCATGGCCGCGTTCTCGCTC
GGGCTGTCGGCGCGCATCGTGATGCGTTTCGGCATCCGCGGCCCGATCGCGGCCGGCCTGCTGCTCGCGGCGTGCGGCCT
CGCGCTGTTCTCGCGCGCACCGGTCGACGGCGGTTTCGTGTGGCACGTGCTGCCCGGCATGACGCTGCTCGGCATCGGCG
CGGGCGTCGCGTTCAACCCGGTGCTGCTCGCCGCGATGAACGACGTCGACCCGGCCGATTCCGGGCTCGCGTCAGGCATC
GTCAACACGTCGTTCATGATGGGCGGCGCGCTCGGGCTCGCGATCCTCGCGAGTCTCGCCGGCGCCCGCACCGACGCGCT
CGCGGCGACGCAAGCCGCGCCGCTCGACGCGCTGAACGGCGGCTACCACGCGGCCTTCGCGTTCGGCGCGGCGTTTGCCG
CCGTGGCCGCGCTGACCGGTTTGGCGCTGCGCATCCGGGCGCCACGCGCGGTCGAAGGCGCCGGCCCCGCGATGCACTGA

Upstream 100 bases:

>100_bases
CGCGCCACTACGCGACGCTCCTGCCACAAACCGGCAGGAAGCCCGCGCCGGCGACCTCTACAATGCATCCTTCAAATAAC
GATCAGAAGGCTGCAGGCCC

Downstream 100 bases:

>100_bases
CCGTCGACGGGGAAACCGGGGAACCGGGGAACCGGGGAACCGGGGAACCGGCATCGGAGCAGGGCACGCGTTGTCGCGCC
TCTTTTTTATGCGCGTCGGA

Product: EmrB/QacA family drug resistance transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTHGIHGEKRWYALIVLCLGVLMIVLDSTIVNVALPSISTDLHFTETALVWVVNAYLLTFGGCLLLGGRLGDLYGQRRMF
LAGLVVFTLASLACGLAQSQAMLIAARAVQGLGGAVVSAVSLSLIMNLFTEPGERARAMGVYGFVCAGGGSIGVLLGGLL
TSSLSWHWIFLVNLPIGVAVYAMCVALLPRVRAPAGTARLDVAGAITVTASLMLAVYGIVGGNEAGWLSTQTVALIGAAV
VLLALFIAIESRAAHPLMPLTLFAARNVALANAIAVLWAAAMFAWFFLSALYMQRVLGYGPLQVGLAFLPANLIMAAFSL
GLSARIVMRFGIRGPIAAGLLLAACGLALFSRAPVDGGFVWHVLPGMTLLGIGAGVAFNPVLLAAMNDVDPADSGLASGI
VNTSFMMGGALGLAILASLAGARTDALAATQAAPLDALNGGYHAAFAFGAAFAAVAALTGLALRIRAPRAVEGAGPAMH

Sequences:

>Translated_479_residues
MTHGIHGEKRWYALIVLCLGVLMIVLDSTIVNVALPSISTDLHFTETALVWVVNAYLLTFGGCLLLGGRLGDLYGQRRMF
LAGLVVFTLASLACGLAQSQAMLIAARAVQGLGGAVVSAVSLSLIMNLFTEPGERARAMGVYGFVCAGGGSIGVLLGGLL
TSSLSWHWIFLVNLPIGVAVYAMCVALLPRVRAPAGTARLDVAGAITVTASLMLAVYGIVGGNEAGWLSTQTVALIGAAV
VLLALFIAIESRAAHPLMPLTLFAARNVALANAIAVLWAAAMFAWFFLSALYMQRVLGYGPLQVGLAFLPANLIMAAFSL
GLSARIVMRFGIRGPIAAGLLLAACGLALFSRAPVDGGFVWHVLPGMTLLGIGAGVAFNPVLLAAMNDVDPADSGLASGI
VNTSFMMGGALGLAILASLAGARTDALAATQAAPLDALNGGYHAAFAFGAAFAAVAALTGLALRIRAPRAVEGAGPAMH
>Mature_478_residues
THGIHGEKRWYALIVLCLGVLMIVLDSTIVNVALPSISTDLHFTETALVWVVNAYLLTFGGCLLLGGRLGDLYGQRRMFL
AGLVVFTLASLACGLAQSQAMLIAARAVQGLGGAVVSAVSLSLIMNLFTEPGERARAMGVYGFVCAGGGSIGVLLGGLLT
SSLSWHWIFLVNLPIGVAVYAMCVALLPRVRAPAGTARLDVAGAITVTASLMLAVYGIVGGNEAGWLSTQTVALIGAAVV
LLALFIAIESRAAHPLMPLTLFAARNVALANAIAVLWAAAMFAWFFLSALYMQRVLGYGPLQVGLAFLPANLIMAAFSLG
LSARIVMRFGIRGPIAAGLLLAACGLALFSRAPVDGGFVWHVLPGMTLLGIGAGVAFNPVLLAAMNDVDPADSGLASGIV
NTSFMMGGALGLAILASLAGARTDALAATQAAPLDALNGGYHAAFAFGAAFAAVAALTGLALRIRAPRAVEGAGPAMH

Specific function: Involved in cephamycin export [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=426, Percent_Identity=32.3943661971831, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1789042, Length=450, Percent_Identity=26.6666666666667, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1790195, Length=420, Percent_Identity=30, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788710, Length=456, Percent_Identity=26.0964912280702, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788392, Length=426, Percent_Identity=29.81220657277, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790146, Length=169, Percent_Identity=25.4437869822485, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082320, Length=201, Percent_Identity=27.363184079602, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324954, Length=396, Percent_Identity=26.7676767676768, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319770, Length=294, Percent_Identity=26.8707482993197, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=457, Percent_Identity=24.507658643326, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322958, Length=386, Percent_Identity=24.0932642487047, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=127, Percent_Identity=34.6456692913386, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323520, Length=269, Percent_Identity=26.7657992565056, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=309, Percent_Identity=24.2718446601942, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49024; Mature: 48893

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHGIHGEKRWYALIVLCLGVLMIVLDSTIVNVALPSISTDLHFTETALVWVVNAYLLTF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
GGCLLLGGRLGDLYGQRRMFLAGLVVFTLASLACGLAQSQAMLIAARAVQGLGGAVVSAV
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SLSLIMNLFTEPGERARAMGVYGFVCAGGGSIGVLLGGLLTSSLSWHWIFLVNLPIGVAV
HHHHHHHHHCCCCHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHH
YAMCVALLPRVRAPAGTARLDVAGAITVTASLMLAVYGIVGGNEAGWLSTQTVALIGAAV
HHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
VLLALFIAIESRAAHPLMPLTLFAARNVALANAIAVLWAAAMFAWFFLSALYMQRVLGYG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLQVGLAFLPANLIMAAFSLGLSARIVMRFGIRGPIAAGLLLAACGLALFSRAPVDGGFV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
WHVLPGMTLLGIGAGVAFNPVLLAAMNDVDPADSGLASGIVNTSFMMGGALGLAILASLA
HHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GARTDALAATQAAPLDALNGGYHAAFAFGAAFAAVAALTGLALRIRAPRAVEGAGPAMH
CCCHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
THGIHGEKRWYALIVLCLGVLMIVLDSTIVNVALPSISTDLHFTETALVWVVNAYLLTF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
GGCLLLGGRLGDLYGQRRMFLAGLVVFTLASLACGLAQSQAMLIAARAVQGLGGAVVSAV
CHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SLSLIMNLFTEPGERARAMGVYGFVCAGGGSIGVLLGGLLTSSLSWHWIFLVNLPIGVAV
HHHHHHHHHCCCCHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEEEECCHHHHH
YAMCVALLPRVRAPAGTARLDVAGAITVTASLMLAVYGIVGGNEAGWLSTQTVALIGAAV
HHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
VLLALFIAIESRAAHPLMPLTLFAARNVALANAIAVLWAAAMFAWFFLSALYMQRVLGYG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLQVGLAFLPANLIMAAFSLGLSARIVMRFGIRGPIAAGLLLAACGLALFSRAPVDGGFV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCH
WHVLPGMTLLGIGAGVAFNPVLLAAMNDVDPADSGLASGIVNTSFMMGGALGLAILASLA
HHHHCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GARTDALAATQAAPLDALNGGYHAAFAFGAAFAAVAALTGLALRIRAPRAVEGAGPAMH
CCCHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]