BacMap

Definition	Burkholderia cenocepacia AU 1054 chromosome 1, complete sequence.
Accession	NC_008060
Length	3,294,563

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The map label for this gene is ydfG [H]

Identifier: 107021880

GI number: 107021880

Start: 358326

End: 359072

Strand: Reverse

Name: ydfG [H]

Synonym: Bcen_0322

Alternate gene names: 107021880

Gene position: 359072-358326 (Counterclockwise)

Preceding gene: 107021884

Following gene: 107021879

Centisome position: 10.9

GC content: 67.6

Gene sequence:

>747_bases
ATGATCGTGTTCGTCACAGGTGCGTCCGCCGGCTTCGGCGCCGCCATCTCCCGTGCCTTCGTCAAGGGCGGCCATCGCGT
CGTCGCCACCGCACGCCGCAAGGATCGCCTCGATGCGCTCGCGGCCGAACTCGGCGACGCGCTGCTGCCGTTCGAGCTCG
ACGTGCGCGACCGCGCGGCCGTCGAAGCCGTGCCGGCCGCCCTTCCCGCCGAATTCGCGGCGCTCGACGTGCTCGTCAAC
AACGCCGGCCTCGCGCTCGGCGTCGAGCCGGCCCAGAAGGCGAGCCTCGACGAGTGGCAGACCATGATCGACACGAACTG
CTCGGGCCTCGTGACCGTCACGCACGCATTGCTGCCGGGCATGATCGCGCGCGGTCGCGGCCATATCTTCAATCTGGGTT
CGGTGGCCGGCACCTATCCGTATCCGGGCGGGAACGTCTACGGCGCGACCAAGGCTTTCGTCAGACAATTCAGCCTGAAC
CTGCGCACTGACCTGATCGGCACGCCGTTGCGCGTCACCGACATCGAACCGGGCCTGTGCGGCGGCACGGAATTCTCGAA
CGTCCGCTTCCGCGGCGACGATGCAAAGGCGGCGAACGTCTACCAGAACGTCCAGCCGCTCACGGCGGAGGACATCGCCG
ATACGATCTACTGGATCGCCACGCGCCCCGCGCACGTCAACATCAATACGATCGAAATGATGCCGGTCGCGCAAGCGCCG
GCCGGCCTCACGATCCATCGCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCCCGTGCCGACACGCTTCGCCGTCTTGCCGCGGTGCGGCATTCTCAGTAGGCTTGCGGGATTCCACCCGCTATTCC
GTTACCGACCAGGAGCAGCA

Downstream 100 bases:

>100_bases
CCGTCGCTCGCAGCCGCGGGCCCGCCTCCGGGCGGCCCGCGGTGTGCTACGACGCACTACATTCCGTTACGAATCGGTTA
CGAATCGGGCCTTTGCCTTC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIVFVTGASAGFGAAISRAFVKGGHRVVATARRKDRLDALAAELGDALLPFELDVRDRAAVEAVPAALPAEFAALDVLVN
NAGLALGVEPAQKASLDEWQTMIDTNCSGLVTVTHALLPGMIARGRGHIFNLGSVAGTYPYPGGNVYGATKAFVRQFSLN
LRTDLIGTPLRVTDIEPGLCGGTEFSNVRFRGDDAKAANVYQNVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP
AGLTIHRG

Sequences:

>Translated_248_residues
MIVFVTGASAGFGAAISRAFVKGGHRVVATARRKDRLDALAAELGDALLPFELDVRDRAAVEAVPAALPAEFAALDVLVN
NAGLALGVEPAQKASLDEWQTMIDTNCSGLVTVTHALLPGMIARGRGHIFNLGSVAGTYPYPGGNVYGATKAFVRQFSLN
LRTDLIGTPLRVTDIEPGLCGGTEFSNVRFRGDDAKAANVYQNVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP
AGLTIHRG
>Mature_248_residues
MIVFVTGASAGFGAAISRAFVKGGHRVVATARRKDRLDALAAELGDALLPFELDVRDRAAVEAVPAALPAEFAALDVLVN
NAGLALGVEPAQKASLDEWQTMIDTNCSGLVTVTHALLPGMIARGRGHIFNLGSVAGTYPYPGGNVYGATKAFVRQFSLN
LRTDLIGTPLRVTDIEPGLCGGTEFSNVRFRGDDAKAANVYQNVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP
AGLTIHRG

Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=32.6612903225806, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI7706318, Length=186, Percent_Identity=34.9462365591398, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7657478, Length=183, Percent_Identity=36.0655737704918, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=31.3829787234043, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI40548397, Length=179, Percent_Identity=32.4022346368715, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI214010158, Length=179, Percent_Identity=32.4022346368715, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI214010156, Length=179, Percent_Identity=32.4022346368715, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI22758144, Length=179, Percent_Identity=32.4022346368715, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI150247226, Length=190, Percent_Identity=33.1578947368421, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=30.0518134715026, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI157739938, Length=184, Percent_Identity=29.3478260869565, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI22507405, Length=273, Percent_Identity=27.1062271062271, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI4557649, Length=178, Percent_Identity=29.2134831460674, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19743808, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI40254992, Length=178, Percent_Identity=28.6516853932584, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI10190704, Length=228, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=65.9919028340081, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=30.9322033898305, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082100, Length=180, Percent_Identity=34.4444444444444, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=28.8065843621399, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=179, Percent_Identity=29.0502793296089, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=239, Percent_Identity=24.6861924686192, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=238, Percent_Identity=24.3697478991597, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=245, Percent_Identity=27.3469387755102, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=189, Percent_Identity=27.5132275132275, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=242, Percent_Identity=28.099173553719, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=188, Percent_Identity=28.1914893617021, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=184, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=223, Percent_Identity=27.3542600896861, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=25.9109311740891, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=245, Percent_Identity=26.9387755102041, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=246, Percent_Identity=28.0487804878049, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=188, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=191, Percent_Identity=28.2722513089005, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=180, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=38.2113821138211, Blast_Score=164, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=26.1306532663317, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=33.4661354581673, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281364494, Length=248, Percent_Identity=30.241935483871, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=36.0215053763441, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21358495, Length=185, Percent_Identity=32.4324324324324, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357041, Length=182, Percent_Identity=31.8681318681319, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28571526, Length=236, Percent_Identity=27.9661016949153, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=30.6122448979592, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584748, Length=179, Percent_Identity=30.7262569832402, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI161076933, Length=179, Percent_Identity=30.7262569832402, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI23397609, Length=229, Percent_Identity=28.3842794759825, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=176, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24663911, Length=247, Percent_Identity=27.5303643724696, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=31.6, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=28.2352941176471, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116007234, Length=251, Percent_Identity=31.0756972111554, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=28.8, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=28.9340101522843, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=30.0546448087432, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=28.5140562248996, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=28.5140562248996, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580925, Length=230, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=27.810650887574, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584752, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26208; Mature: 26208

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFVTGASAGFGAAISRAFVKGGHRVVATARRKDRLDALAAELGDALLPFELDVRDRAA
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEECCCHHHH
VEAVPAALPAEFAALDVLVNNAGLALGVEPAQKASLDEWQTMIDTNCSGLVTVTHALLPG
HHHHCCCCCHHHHHEEEEECCCCEEEECCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
MIARGRGHIFNLGSVAGTYPYPGGNVYGATKAFVRQFSLNLRTDLIGTPLRVTDIEPGLC
HHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCC
GGTEFSNVRFRGDDAKAANVYQNVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP
CCCCCCCEEEECCCCHHHHHHHCCCCCCHHHHHHHEEEEEECCCEEEEEEEEEEECCCCC
AGLTIHRG
CCEEEECC
>Mature Secondary Structure
MIVFVTGASAGFGAAISRAFVKGGHRVVATARRKDRLDALAAELGDALLPFELDVRDRAA
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEECCCHHHH
VEAVPAALPAEFAALDVLVNNAGLALGVEPAQKASLDEWQTMIDTNCSGLVTVTHALLPG
HHHHCCCCCHHHHHEEEEECCCCEEEECCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
MIARGRGHIFNLGSVAGTYPYPGGNVYGATKAFVRQFSLNLRTDLIGTPLRVTDIEPGLC
HHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCEEEEECCCCCC
GGTEFSNVRFRGDDAKAANVYQNVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP
CCCCCCCEEEECCCCHHHHHHHCCCCCCHHHHHHHEEEEEECCCEEEEEEEEEEECCCCC
AGLTIHRG
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]