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The map label for this gene is ffh [H]

Identifier: 107021668

GI number: 107021668

Start: 112439

End: 113806

Strand: Reverse

Name: ffh [H]

Synonym: Bcen_0108

Alternate gene names: 107021668

Gene position: 113806-112439 (Counterclockwise)

Preceding gene: 107021676

Following gene: 107021667

Centisome position: 3.45

GC content: 66.59

Gene sequence:

>1368_bases
ATGCTCGACAATCTCACTCAACGGATGGCGCGCGTCGTCAAGACGCTGCGCGGCGAGGCCCGGCTCACCGAGGCGAACAC
GCAGGAGATGCTCCGCGAGGTGCGTCTCGCGCTGCTGGAAGCCGACGTGTCGCTGCCGGTCGTCCGCGAATTCATCGCCA
AGGTCAAGGAAAAGGCGCTCGGCGAAGAAGTGATCAGCAGCCTGTCGCCGGGCCAGGCGCTCGTCGGCGTGGTCCAGAAG
GAACTGACCGCCGTGATCGGCGGCGACTACGAAGGCAAGGCCGCCGAGCTGAACCTCGCGGTCACGCCGCCCGCCGTGAT
CCTGATGGCCGGCCTGCAGGGCGCCGGCAAGACCACGACCGTCGGCAAGCTCGCGAAGCTGCTGCGCGAGAAGTACAAGA
AGAAGGTGCTGACCGTGTCGTGCGACGTGTATCGCCCGGCCGCGATCATGCAGCTGAAAACGGTGACCGAGCAGGTCGGC
GCCGACTTCTTCCCGTCCACGCCGGACCAGAAGCCCGTCGACATCGCGCTCGCCGCCGTCGACTGGGCGAAGCGCCACTA
CCATGACGTGCTGCTCGTCGACACGGCCGGCCGCCTCGGCATCGACGAGGCGATGATGCAGGAAATCGCCGCGCTGCACG
GCACGCTGAAGCCGGCCGAAACGCTGTTCGTCGTCGACGCGATGCTCGGCCAGGACGCGGTCAACACCGCGAAGGCGTTC
AACGACACGCTGCCGCTCACCGGCGTCGTGCTGACCAAGCTCGACGGCGATTCGCGCGGCGGCGCCGCGCTGTCGGTGCG
CCACGTCACGGGCAAACCGATCAAGTTCGTCGGCGTCGCCGAGAAGCTCGACGGCCTCGAGGTGTTCCACCCCGACCGGA
TGGCGAACCGGATCCTCGGCATGGGCGACATCCTCGCGCTCGTCGAGGAAGCGCAGCGCGGCGTCGATGTCCAGGCCGCG
CAGAAGCTCGCCGACAAGGTCAAGAAAGGCGGCGACTTCGACCTGAACGATTTCCGCGCGCAGATCTCGCAGATGAAGAA
CATGGGCGGCCTGTCGTCGCTGATGGACAAACTCCCCGCGCAGTTCCAGCAGGCGGCGGCCGGCGCCGACATGGGTCAGG
CCGAAAAGTCGATCCGCCGGATGGAAGGCATCATCAGCTCGATGACGCCCGCCGAGCGCGCGAAACCCGAAATCATCAAG
GCGACGCGCAAGCGCCGCATCGCAGCCGGCGCGGGCGTGCCGGTGCAGGAAGTCAACCGGATGCTGAACCAGTACGACCA
GATGCGTACGATGATGAAGAAGCTGAAGGGCGGCAACATGCAGAAGATGATGCGCGGCCTGAAGGGCATGATGCCCGGCA
TGCGCTGA

Upstream 100 bases:

>100_bases
CAATATCCATGTTCGAAGTTTACACTAGGCCCCCTTCCCGCGACGGCTCCCTTTTGTTCGGTTCCGCCGCGCCTTCGGGC
CCCACTGTCCAACGCTCCCC

Downstream 100 bases:

>100_bases
TTTCGTCCGTCGGCCGGCGCGCGGGTTTTTGCCGTAGCGCGCGCCTGCCGTTCTGCTTCATCCTTATTTGTATACCGACT
GCCCGCCAGAACACATGAAC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVSLPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAAELNLAVTPPAVILMAGLQGAGKTTTVGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVTEQVG
ADFFPSTPDQKPVDIALAAVDWAKRHYHDVLLVDTAGRLGIDEAMMQEIAALHGTLKPAETLFVVDAMLGQDAVNTAKAF
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKSIRRMEGIISSMTPAERAKPEIIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGMR

Sequences:

>Translated_455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVSLPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAAELNLAVTPPAVILMAGLQGAGKTTTVGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVTEQVG
ADFFPSTPDQKPVDIALAAVDWAKRHYHDVLLVDTAGRLGIDEAMMQEIAALHGTLKPAETLFVVDAMLGQDAVNTAKAF
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKSIRRMEGIISSMTPAERAKPEIIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGMR
>Mature_455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVSLPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAAELNLAVTPPAVILMAGLQGAGKTTTVGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVTEQVG
ADFFPSTPDQKPVDIALAAVDWAKRHYHDVLLVDTAGRLGIDEAMMQEIAALHGTLKPAETLFVVDAMLGQDAVNTAKAF
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKSIRRMEGIISSMTPAERAKPEIIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGMR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=458, Percent_Identity=30.3493449781659, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI226371618, Length=397, Percent_Identity=30.4785894206549, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI89061728, Length=165, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI23308697, Length=202, Percent_Identity=33.1683168316832, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI295424842, Length=202, Percent_Identity=33.1683168316832, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788963, Length=452, Percent_Identity=64.6017699115044, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1789874, Length=278, Percent_Identity=33.0935251798561, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=461, Percent_Identity=29.0672451193059, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI193206261, Length=202, Percent_Identity=34.6534653465347, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=451, Percent_Identity=30.820399113082, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI17647949, Length=445, Percent_Identity=30.561797752809, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24641198, Length=271, Percent_Identity=29.1512915129151, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49269; Mature: 49269

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVSLPVVREFIAKVKEKAL
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAAELNLAVTPPAVILMAGLQGAGKTTT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCHH
VGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVTEQVGADFFPSTPDQKPVDIALAAV
HHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
DWAKRHYHDVLLVDTAGRLGIDEAMMQEIAALHGTLKPAETLFVVDAMLGQDAVNTAKAF
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILG
CCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHC
MGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
QFQQAAAGADMGQAEKSIRRMEGIISSMTPAERAKPEIIKATRKRRIAAGAGVPVQEVNR
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
MLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGMR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVSLPVVREFIAKVKEKAL
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAAELNLAVTPPAVILMAGLQGAGKTTT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHCCCCCCCCHH
VGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVTEQVGADFFPSTPDQKPVDIALAAV
HHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
DWAKRHYHDVLLVDTAGRLGIDEAMMQEIAALHGTLKPAETLFVVDAMLGQDAVNTAKAF
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHH
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILG
CCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHC
MGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
QFQQAAAGADMGQAEKSIRRMEGIISSMTPAERAKPEIIKATRKRRIAAGAGVPVQEVNR
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
MLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGMR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]