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The map label for this gene is hpt [H]

Identifier: 107021667

GI number: 107021667

Start: 111793

End: 112344

Strand: Reverse

Name: hpt [H]

Synonym: Bcen_0107

Alternate gene names: 107021667

Gene position: 112344-111793 (Counterclockwise)

Preceding gene: 107021668

Following gene: 107021664

Centisome position: 3.41

GC content: 65.4

Gene sequence:

>552_bases
ATGAACCGCGAAGAAGCCCTCCACATTTTCGACCACTCCGAAGAGATCGTCTCGGCCGACGCCGTCAACGCGTCGATCTC
GAAGATGGCCGACGCGATCCGCGCCGAAATCGGCGACGCGTTCCCGCTCGTTCTCTCGGTGATGGGCGGCGCCGCGGTGT
TTACCGGGATGCTGCTGCCGCATCTCGATTTCCCGCTCGAATTCGACTACATCCACCTGACCCGCTACCGCAACACGACG
CAGGGCAGCCCGGAGATGCACTGGCGCGTCGCGCCGCGCGAATCGGTGAAGGACCGCATCGTGCTCGTACTCGACGACAT
CCTCGACGAAGGCGAGACGATGGCCGCGATCCGCGACCGCATCCTCGACATGGGCGCGCAGCGCTTCATGTCGGCCGTGC
TGTGCGAGAAGACGCTCGCGAAGGCGAAACCGCTGCACCCCGACTTCTGCGGCTTCTCGGTGCCGGACCGTTACGTGTTC
GGCTGCGGGATGGACGCGAAGGGCTACTGGCGCAACCTGCCGACGATCCGCGCGCTGACCGCGAACGTCTGA

Upstream 100 bases:

>100_bases
CGCTGATTTCGTCCGTCGGCCGGCGCGCGGGTTTTTGCCGTAGCGCGCGCCTGCCGTTCTGCTTCATCCTTATTTGTATA
CCGACTGCCCGCCAGAACAC

Downstream 100 bases:

>100_bases
TCGCCGCCCGGCCTGCTATATAAATGGAAAGCGGCGCTCCGGTTGCCCGGAGCGCCGCTTTTTTTCGCGCGTGCCGCCTG
CGTTACAACTGGTGCACGAA

Product: hypoxanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: HGPRT; HGPRTase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNREEALHIFDHSEEIVSADAVNASISKMADAIRAEIGDAFPLVLSVMGGAAVFTGMLLPHLDFPLEFDYIHLTRYRNTT
QGSPEMHWRVAPRESVKDRIVLVLDDILDEGETMAAIRDRILDMGAQRFMSAVLCEKTLAKAKPLHPDFCGFSVPDRYVF
GCGMDAKGYWRNLPTIRALTANV

Sequences:

>Translated_183_residues
MNREEALHIFDHSEEIVSADAVNASISKMADAIRAEIGDAFPLVLSVMGGAAVFTGMLLPHLDFPLEFDYIHLTRYRNTT
QGSPEMHWRVAPRESVKDRIVLVLDDILDEGETMAAIRDRILDMGAQRFMSAVLCEKTLAKAKPLHPDFCGFSVPDRYVF
GCGMDAKGYWRNLPTIRALTANV
>Mature_183_residues
MNREEALHIFDHSEEIVSADAVNASISKMADAIRAEIGDAFPLVLSVMGGAAVFTGMLLPHLDFPLEFDYIHLTRYRNTT
QGSPEMHWRVAPRESVKDRIVLVLDDILDEGETMAAIRDRILDMGAQRFMSAVLCEKTLAKAKPLHPDFCGFSVPDRYVF
GCGMDAKGYWRNLPTIRALTANV

Specific function: This Enzyme Acts Exclusively On Hypoxanthine; It Does Not Act On Guanine (By Similarity). [C]

COG id: COG0634

COG function: function code F; Hypoxanthine-guanine phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17510817, Length=170, Percent_Identity=25.8823529411765, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005904
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.8 [H]

Molecular weight: Translated: 20427; Mature: 20427

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNREEALHIFDHSEEIVSADAVNASISKMADAIRAEIGDAFPLVLSVMGGAAVFTGMLLP
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HLDFPLEFDYIHLTRYRNTTQGSPEMHWRVAPRESVKDRIVLVLDDILDEGETMAAIRDR
CCCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ILDMGAQRFMSAVLCEKTLAKAKPLHPDFCGFSVPDRYVFGCGMDAKGYWRNLPTIRALT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCCHHHHEE
ANV
CCC
>Mature Secondary Structure
MNREEALHIFDHSEEIVSADAVNASISKMADAIRAEIGDAFPLVLSVMGGAAVFTGMLLP
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
HLDFPLEFDYIHLTRYRNTTQGSPEMHWRVAPRESVKDRIVLVLDDILDEGETMAAIRDR
CCCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ILDMGAQRFMSAVLCEKTLAKAKPLHPDFCGFSVPDRYVFGCGMDAKGYWRNLPTIRALT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHCCCHHHHEE
ANV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]