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The map label for this gene is dcp [H]

Identifier: 103488636

GI number: 103488636

Start: 3309753

End: 3311939

Strand: Direct

Name: dcp [H]

Synonym: Sala_3161

Alternate gene names: 103488636

Gene position: 3309753-3311939 (Clockwise)

Preceding gene: 103488635

Following gene: 103488640

Centisome position: 98.94

GC content: 62.96

Gene sequence:

>2187_bases
ATGCCGCAGAGCGCGCCCCGCCTTGCCCGCAAGCTGTCGATCATGCTTGCATCCACCGCGATGATCATGGGTTATGGCCC
GATGAGCACCGCCATCGCCGCCGAACCCGCCGCCGCCAAAACCGTCCCCGCAGGACAGAACCCGCTGCTGCAACCCTGGA
CCGGCCCCTATCAGGGGGTGCCGCCGTGGGACAAGCTCGACCCCGAACTTTTCCCCGACGCCTTTCAGAAGGCGATGGCC
GAGGTGAAGGCCGAAGTGCAGGCGGTGATCGACAACCCCGCCGAACCGACGTTCGAAAACACCCACGTCCCGATGATGCT
CGCGGGCGAGACGATGGAGCGCGTCTTTGCGATGTGGGGCGTGCAGACGTCGAACAAATCGAACGATCGCGTCGAGGAAA
TCGACGCCGAATGGAGCCCGAGGCTCACCACCTTCTACACCGAGCTGTTCCTCGATCCCAAACTCTTCGCGCGCTACAAG
GCGGTGTACGACAAGCGCCACACGAGCGGGCTCGACGCGCAGCAGATCCGCATCGTCGAGCGCAGCCATGACGAAATGGT
GCGCGACGGCGCGAACCTGTCCCCGGCGGACAAGGAAAAGCTGGTCGCGATGAACGCGAAGCTCGAAGGCCTCTTCTCGG
CTTTCTCCTCAAAGCTGCTCGGCGATGAAAAGCTCTACACCTTCGTCACCGACAAGGCCGAGCTCGACGGGCTCGACCCG
GCTTTCGTCGCGTCGCTTGCCGCCGCGGCGGAGGCCAACGGCCATGCCGGTCACTGGGCGATCAAGAATACGCGCTCGTC
GGCGCAACCGGTGCTGCAGAATGCGACCAACCGCAAATTGCGCGAAAAGGTCTGGCGCGCCTTCGTCGGCCGCGGCGACA
ATGGTGACGCCAACGACACCAATGCGACGATCGCCGAAATCCTGAAGCTGCGCCAGCAGCGCGCCGAACTGCTCGGTTTC
CCGACCCACGCGCATTACCGCATGGCCGACACGATGGCGAAGACGCCCGACAATGCGATGGGTCTGATGATGAAGGTGTG
GCCCGCCGCCGTCGCGCGCGTGAAGGAAGAGGTCGCCGACATGCAGGCGATCGCCGACGCCGAAGCCAGGGCGGGCAAGG
GGCCGAAGATCACCATCGAGCCATGGGACTATCGCTATTATGCCGAAAAGGTCCGCAAGGCGAAATATGACCTCGATGAA
AGCGAGGTGAAGCCCTATCTTCAGCTCGACAAGCTGGTCGACGGCATGTTCTGGGCCGCGGGTCGGCTCTATGACCTCGG
CTTCCGCGAGAATACGGGGCAGATTCCGGTTTTCGATCCCAAGGTGCGGACCTTCGAGGTTTATAACCTCAAGACGAACG
AGAATGTCGGCGTCTTCTACCTCGACAATTTCGCGCGCGACGGAAAGCGGTCGGGCGCGTGGATGACGACCTATCGCAGC
CAGCAGTCGCTCGGCGGCGAGCGCAACGTCCTTGCCTCGAACAACAATAATTTCACCGAAGGCGCACAGGGCGAACCGAC
GCTCATCAGCATCGACGACGCCTCGACCTTGTTCCACGAGTTCGGCCACGGCATCCATTATCTGCTCCAGCAGGTCAAAT
ATCCGGCGCTCGCCGGGGTGCCGCGCGATTTCGTCGAATATCCCAGCCAGGTGAACGAAAACTGGCTGATGACCCCCGAA
GTGCTGTCGAAATATGCGACGCACTACCGGACGGGCGAGCCGATGCCGCAGGTGCTGGTCGACAAGATCCTCGCGAGCCA
GAAGTTCAACCAGGGGTTCGAGACGGTCGAATATCTGGCGAGCGCGATCGTCGACATGAAGCTGCACGACCGCAAGACCC
CGCCGACCGACGTCGACAGGTTCGAACGCGAGACGCTGGCCGAAATCGGAATGCCAAAGGAAATCGTCATGCGGCACCGC
CTGCCGCAGTTCGGCCACCTGTTCAGCTCGGACGCCTATTCGGCGGGCTATTACTCCTACCTCTGGTCCGAAACGATGGA
CGCCGACACCTGGGCGGCTTTCACCGAAGCCGGCGGCCCGTGGGACCGCAGCGTTGCCGACAGGTTCCGCACCATTTTGC
TCATGACCGGCAACGAGACCGACCGCGCCGAGGCCTATCGCGCCTTCCGCGGCCGCGACCCCGACGTCAAGGCGCTGCTC
GAAAAGCGCGGTTTCCCGACCGAATAA

Upstream 100 bases:

>100_bases
TCGCGCGGCAACCCGAAACTTGCGCATCGCTGTCATATCTGGTTAATCCACCGCCCGACATGGTTTCGTCCGAAACCTTT
TCCACCGGGAGAATCCGAAT

Downstream 100 bases:

>100_bases
AGGGCAAGGCAAAGGGGGTCGTTTCGGGCCCCCTTTGTTTGTGCGGGCGACGCCGGCCCACGGTTGCCTCGATCATCGGG
ATGACCGCTTTCGACCGAAG

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MPQSAPRLARKLSIMLASTAMIMGYGPMSTAIAAEPAAAKTVPAGQNPLLQPWTGPYQGVPPWDKLDPELFPDAFQKAMA
EVKAEVQAVIDNPAEPTFENTHVPMMLAGETMERVFAMWGVQTSNKSNDRVEEIDAEWSPRLTTFYTELFLDPKLFARYK
AVYDKRHTSGLDAQQIRIVERSHDEMVRDGANLSPADKEKLVAMNAKLEGLFSAFSSKLLGDEKLYTFVTDKAELDGLDP
AFVASLAAAAEANGHAGHWAIKNTRSSAQPVLQNATNRKLREKVWRAFVGRGDNGDANDTNATIAEILKLRQQRAELLGF
PTHAHYRMADTMAKTPDNAMGLMMKVWPAAVARVKEEVADMQAIADAEARAGKGPKITIEPWDYRYYAEKVRKAKYDLDE
SEVKPYLQLDKLVDGMFWAAGRLYDLGFRENTGQIPVFDPKVRTFEVYNLKTNENVGVFYLDNFARDGKRSGAWMTTYRS
QQSLGGERNVLASNNNNFTEGAQGEPTLISIDDASTLFHEFGHGIHYLLQQVKYPALAGVPRDFVEYPSQVNENWLMTPE
VLSKYATHYRTGEPMPQVLVDKILASQKFNQGFETVEYLASAIVDMKLHDRKTPPTDVDRFERETLAEIGMPKEIVMRHR
LPQFGHLFSSDAYSAGYYSYLWSETMDADTWAAFTEAGGPWDRSVADRFRTILLMTGNETDRAEAYRAFRGRDPDVKALL
EKRGFPTE

Sequences:

>Translated_728_residues
MPQSAPRLARKLSIMLASTAMIMGYGPMSTAIAAEPAAAKTVPAGQNPLLQPWTGPYQGVPPWDKLDPELFPDAFQKAMA
EVKAEVQAVIDNPAEPTFENTHVPMMLAGETMERVFAMWGVQTSNKSNDRVEEIDAEWSPRLTTFYTELFLDPKLFARYK
AVYDKRHTSGLDAQQIRIVERSHDEMVRDGANLSPADKEKLVAMNAKLEGLFSAFSSKLLGDEKLYTFVTDKAELDGLDP
AFVASLAAAAEANGHAGHWAIKNTRSSAQPVLQNATNRKLREKVWRAFVGRGDNGDANDTNATIAEILKLRQQRAELLGF
PTHAHYRMADTMAKTPDNAMGLMMKVWPAAVARVKEEVADMQAIADAEARAGKGPKITIEPWDYRYYAEKVRKAKYDLDE
SEVKPYLQLDKLVDGMFWAAGRLYDLGFRENTGQIPVFDPKVRTFEVYNLKTNENVGVFYLDNFARDGKRSGAWMTTYRS
QQSLGGERNVLASNNNNFTEGAQGEPTLISIDDASTLFHEFGHGIHYLLQQVKYPALAGVPRDFVEYPSQVNENWLMTPE
VLSKYATHYRTGEPMPQVLVDKILASQKFNQGFETVEYLASAIVDMKLHDRKTPPTDVDRFERETLAEIGMPKEIVMRHR
LPQFGHLFSSDAYSAGYYSYLWSETMDADTWAAFTEAGGPWDRSVADRFRTILLMTGNETDRAEAYRAFRGRDPDVKALL
EKRGFPTE
>Mature_727_residues
PQSAPRLARKLSIMLASTAMIMGYGPMSTAIAAEPAAAKTVPAGQNPLLQPWTGPYQGVPPWDKLDPELFPDAFQKAMAE
VKAEVQAVIDNPAEPTFENTHVPMMLAGETMERVFAMWGVQTSNKSNDRVEEIDAEWSPRLTTFYTELFLDPKLFARYKA
VYDKRHTSGLDAQQIRIVERSHDEMVRDGANLSPADKEKLVAMNAKLEGLFSAFSSKLLGDEKLYTFVTDKAELDGLDPA
FVASLAAAAEANGHAGHWAIKNTRSSAQPVLQNATNRKLREKVWRAFVGRGDNGDANDTNATIAEILKLRQQRAELLGFP
THAHYRMADTMAKTPDNAMGLMMKVWPAAVARVKEEVADMQAIADAEARAGKGPKITIEPWDYRYYAEKVRKAKYDLDES
EVKPYLQLDKLVDGMFWAAGRLYDLGFRENTGQIPVFDPKVRTFEVYNLKTNENVGVFYLDNFARDGKRSGAWMTTYRSQ
QSLGGERNVLASNNNNFTEGAQGEPTLISIDDASTLFHEFGHGIHYLLQQVKYPALAGVPRDFVEYPSQVNENWLMTPEV
LSKYATHYRTGEPMPQVLVDKILASQKFNQGFETVEYLASAIVDMKLHDRKTPPTDVDRFERETLAEIGMPKEIVMRHRL
PQFGHLFSSDAYSAGYYSYLWSETMDADTWAAFTEAGGPWDRSVADRFRTILLMTGNETDRAEAYRAFRGRDPDVKALLE
KRGFPTE

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=597, Percent_Identity=28.9782244556114, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI14149738, Length=695, Percent_Identity=25.8992805755396, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI156105687, Length=548, Percent_Identity=24.4525547445255, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1787819, Length=686, Percent_Identity=38.0466472303207, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1789913, Length=692, Percent_Identity=31.6473988439306, Blast_Score=327, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI32565901, Length=425, Percent_Identity=24, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71999758, Length=584, Percent_Identity=20.7191780821918, Blast_Score=90, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319793, Length=683, Percent_Identity=25.1830161054173, Blast_Score=194, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322715, Length=689, Percent_Identity=21.9158200290276, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21356111, Length=584, Percent_Identity=25.1712328767123, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI20129717, Length=437, Percent_Identity=22.6544622425629, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 81747; Mature: 81616

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSAPRLARKLSIMLASTAMIMGYGPMSTAIAAEPAAAKTVPAGQNPLLQPWTGPYQGV
CCCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPWDKLDPELFPDAFQKAMAEVKAEVQAVIDNPAEPTFENTHVPMMLAGETMERVFAMWG
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHC
VQTSNKSNDRVEEIDAEWSPRLTTFYTELFLDPKLFARYKAVYDKRHTSGLDAQQIRIVE
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RSHDEMVRDGANLSPADKEKLVAMNAKLEGLFSAFSSKLLGDEKLYTFVTDKAELDGLDP
HHHHHHHHCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCCCCH
AFVASLAAAAEANGHAGHWAIKNTRSSAQPVLQNATNRKLREKVWRAFVGRGDNGDANDT
HHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NATIAEILKLRQQRAELLGFPTHAHYRMADTMAKTPDNAMGLMMKVWPAAVARVKEEVAD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MQAIADAEARAGKGPKITIEPWDYRYYAEKVRKAKYDLDESEVKPYLQLDKLVDGMFWAA
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHC
GRLYDLGFRENTGQIPVFDPKVRTFEVYNLKTNENVGVFYLDNFARDGKRSGAWMTTYRS
CCEEECCCCCCCCCCCEECCCCEEEEEEEEECCCCCEEEEECCHHCCCCCCCCEEEEECC
QQSLGGERNVLASNNNNFTEGAQGEPTLISIDDASTLFHEFGHGIHYLLQQVKYPALAGV
HHHCCCCCCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHCCCHHCCC
PRDFVEYPSQVNENWLMTPEVLSKYATHYRTGEPMPQVLVDKILASQKFNQGFETVEYLA
CHHHHHCHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
SAIVDMKLHDRKTPPTDVDRFERETLAEIGMPKEIVMRHRLPQFGHLFSSDAYSAGYYSY
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHCCCCCCCCHHHH
LWSETMDADTWAAFTEAGGPWDRSVADRFRTILLMTGNETDRAEAYRAFRGRDPDVKALL
HHHHCCCCHHHHHHHCCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCCHHHHHH
EKRGFPTE
HHCCCCCC
>Mature Secondary Structure 
PQSAPRLARKLSIMLASTAMIMGYGPMSTAIAAEPAAAKTVPAGQNPLLQPWTGPYQGV
CCCHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPWDKLDPELFPDAFQKAMAEVKAEVQAVIDNPAEPTFENTHVPMMLAGETMERVFAMWG
CCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHC
VQTSNKSNDRVEEIDAEWSPRLTTFYTELFLDPKLFARYKAVYDKRHTSGLDAQQIRIVE
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RSHDEMVRDGANLSPADKEKLVAMNAKLEGLFSAFSSKLLGDEKLYTFVTDKAELDGLDP
HHHHHHHHCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHCCCCCH
AFVASLAAAAEANGHAGHWAIKNTRSSAQPVLQNATNRKLREKVWRAFVGRGDNGDANDT
HHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NATIAEILKLRQQRAELLGFPTHAHYRMADTMAKTPDNAMGLMMKVWPAAVARVKEEVAD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MQAIADAEARAGKGPKITIEPWDYRYYAEKVRKAKYDLDESEVKPYLQLDKLVDGMFWAA
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHC
GRLYDLGFRENTGQIPVFDPKVRTFEVYNLKTNENVGVFYLDNFARDGKRSGAWMTTYRS
CCEEECCCCCCCCCCCEECCCCEEEEEEEEECCCCCEEEEECCHHCCCCCCCCEEEEECC
QQSLGGERNVLASNNNNFTEGAQGEPTLISIDDASTLFHEFGHGIHYLLQQVKYPALAGV
HHHCCCCCCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHHCCCHHCCC
PRDFVEYPSQVNENWLMTPEVLSKYATHYRTGEPMPQVLVDKILASQKFNQGFETVEYLA
CHHHHHCHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
SAIVDMKLHDRKTPPTDVDRFERETLAEIGMPKEIVMRHRLPQFGHLFSSDAYSAGYYSY
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHCCCCCCCCHHHH
LWSETMDADTWAAFTEAGGPWDRSVADRFRTILLMTGNETDRAEAYRAFRGRDPDVKALL
HHHHCCCCHHHHHHHCCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCCHHHHHH
EKRGFPTE
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]