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The map label for this gene is ribE [H]

Identifier: 103488467

GI number: 103488467

Start: 3131768

End: 3132385

Strand: Reverse

Name: ribE [H]

Synonym: Sala_2990

Alternate gene names: 103488467

Gene position: 3132385-3131768 (Counterclockwise)

Preceding gene: 103488468

Following gene: 103488461

Centisome position: 93.64

GC content: 69.09

Gene sequence:

>618_bases
ATGTTCACCGGCATCATCACCGACATCGGCACCATCCGCAGCCGCGAGGATCGCGGCGACACGCGGCTCGTCATCGCGAC
CGCCCATGACACGGCAACGATCGACCTCGGCGCATCGATCGCCTGTTCGGGCGCCTGCCTGACCGTCGTCGACAAGGGAC
GCGATGCGGATGGCGACTGGTTCGCGGTCGATGCCAGCGCCGAGACGCTCGCGCGTACGGCCCCGGGCATGTGGGACGCG
GGGCGCCGCCTCAACATCGAACGCGCGCTCAAGGTTGGCGACGAGCTGGGGGGGCATATCGTCACCGGCCATGTCGACGC
GGTGGGCCGGATCGTCGCGGTCGAACCTGTCGGCGACAGCGTCAAGCTGACGGTCGAGGCGCCCGCCGCGCTGGCGCCGC
ATATCGCGCCCAAGGGGTCGATCACGCTCGACGGCGTGTCGCTGACGGTCAACGAAGTGACCGACCAGCCCGACGGCAGC
GCGCATTTCACGCTCAACATCATCCCGCACACGCAGGCGATGACGACGCTGGACGAAGCGGCGGCGGGGCGACCGGTCAA
TCTGGAGATCGACATTCTCGCGCGCTATCTCGCGCGGATGCAGGCGCGCGCCGCCTAG

Upstream 100 bases:

>100_bases
CGCCGCCGCGCACGGCCGCTGGCGCCTTGCCGACAGCCGGATGCTTGGCAGCGACCGGCTCGACGTCTACGAGCGCGTCA
GGACAATTTGAGGGGCTCCC

Downstream 100 bases:

>100_bases
AGCGATGTGCTGTATATCTGACCCGCCGCGAGTTCGGGATCGGCGGCGATCATCGACCGGCGCATCGCCAGGCGTCCGAT
TCGCAGCAGCTCGGCCTTGC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MFTGIITDIGTIRSREDRGDTRLVIATAHDTATIDLGASIACSGACLTVVDKGRDADGDWFAVDASAETLARTAPGMWDA
GRRLNIERALKVGDELGGHIVTGHVDAVGRIVAVEPVGDSVKLTVEAPAALAPHIAPKGSITLDGVSLTVNEVTDQPDGS
AHFTLNIIPHTQAMTTLDEAAAGRPVNLEIDILARYLARMQARAA

Sequences:

>Translated_205_residues
MFTGIITDIGTIRSREDRGDTRLVIATAHDTATIDLGASIACSGACLTVVDKGRDADGDWFAVDASAETLARTAPGMWDA
GRRLNIERALKVGDELGGHIVTGHVDAVGRIVAVEPVGDSVKLTVEAPAALAPHIAPKGSITLDGVSLTVNEVTDQPDGS
AHFTLNIIPHTQAMTTLDEAAAGRPVNLEIDILARYLARMQARAA
>Mature_205_residues
MFTGIITDIGTIRSREDRGDTRLVIATAHDTATIDLGASIACSGACLTVVDKGRDADGDWFAVDASAETLARTAPGMWDA
GRRLNIERALKVGDELGGHIVTGHVDAVGRIVAVEPVGDSVKLTVEAPAALAPHIAPKGSITLDGVSLTVNEVTDQPDGS
AHFTLNIIPHTQAMTTLDEAAAGRPVNLEIDILARYLARMQARAA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=194, Percent_Identity=33.5051546391753, Blast_Score=97, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=33.1730769230769, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21426; Mature: 21426

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIITDIGTIRSREDRGDTRLVIATAHDTATIDLGASIACSGACLTVVDKGRDADGDW
CCCEEEECCHHHCCCCCCCCEEEEEEECCCCEEEECCCCEEECCEEEEEEECCCCCCCCE
FAVDASAETLARTAPGMWDAGRRLNIERALKVGDELGGHIVTGHVDAVGRIVAVEPVGDS
EEEECCHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCC
VKLTVEAPAALAPHIAPKGSITLDGVSLTVNEVTDQPDGSAHFTLNIIPHTQAMTTLDEA
EEEEEECCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHH
AAGRPVNLEIDILARYLARMQARAA
HCCCCCEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIITDIGTIRSREDRGDTRLVIATAHDTATIDLGASIACSGACLTVVDKGRDADGDW
CCCEEEECCHHHCCCCCCCCEEEEEEECCCCEEEECCCCEEECCEEEEEEECCCCCCCCE
FAVDASAETLARTAPGMWDAGRRLNIERALKVGDELGGHIVTGHVDAVGRIVAVEPVGDS
EEEECCHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCC
VKLTVEAPAALAPHIAPKGSITLDGVSLTVNEVTDQPDGSAHFTLNIIPHTQAMTTLDEA
EEEEEECCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHH
AAGRPVNLEIDILARYLARMQARAA
HCCCCCEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]