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The map label for this gene is ectB [H]

Identifier: 103488427

GI number: 103488427

Start: 3092431

End: 3093738

Strand: Direct

Name: ectB [H]

Synonym: Sala_2950

Alternate gene names: 103488427

Gene position: 3092431-3093738 (Clockwise)

Preceding gene: 103488426

Following gene: 103488428

Centisome position: 92.44

GC content: 65.9

Gene sequence:

>1308_bases
ATGATGATTACGACACCGCAACCGTCCGGCAACCTTCCGGATCGGAGCATTTATGAACGCCGCGAATCGGCGGTGCGCAG
CTACGCCCGGTCGATGCCGCGCCAATTCGGTAAAGCGCAGGGCGTGTGGATGCACGATGATCAGGGCGGGCGTTATCTCG
ACTTCCTGTCGGGCTGTTCGACGCTGAACTATGGCCACAACCATCCGATTTTGAAACAGGCGCTGCTCGACTATATCGCC
GCCGACGGCATCGCCCACGGGCTCGACCTGCACACCGATGCAAAGCAGGACTTTCTCGACACGTTCGAGGAAGTGATCCT
GAAACCGCGCGGGCTCGACCACCGCGTGATGTTCACCGGCCCGACCGGCACCAACGCTGTCGAGGCCGCGATCAAGCTCG
CGCGCAAGGTGACGGGCCGCGAAATGGTGATCGCCTTTACCAACGGCTTTCACGGCATGACGTTGGGCGCGCTCGCCTGC
ACCGGCAATGCGACCAAGCGCGGCGGCGCGGGCGTACCGCTGAGCCACGTCGCGCACGAACCCTATTATGATTATTACGG
TCCCGAGGTCGATACCGCCGAATTGCTCGAACAACGGCTCGCCGACCCGTCGAGCGGGCTCGACGCGCCCGCGGCGATCC
TCGTCGAAACGGTGCAGGGTGAGGGCGGGCTCAATGCCGCCTCGGCCGAATGGCTGCGCCGCATCGCGGGAATCGCGAAG
GCGCATGGCGCGCTGCTGATCGTCGACGACATCCAGGCGGGTTGCGGCCGCACCGGCACCTTCTTCAGCTTCGAGGATAT
GGGCTTCACCCCCGATATCGTGACGCTGGCGAAGTCGCTGTCGGGCATGGGCCTGCCCTTTGCGCTGACCCTGCTGCGTC
CCGAGCTCGACCAATGGTCGCCGGGCGAGCATAACGGCACCTTCCGCGGCAACAACCATGCCTTTGTCACCGCGACCGCC
GCGCTCCGCCATTTCTGGAGCGCCGACGATTTCCAGCGCGACATAGGCCGCCGCGCCGCCCTGCTCGAAACCCGCCTCGC
GCGCATCGCCGCCGAACATGGGTTCGAGGTGCGCGGGCGCGGCATGATGCGCGGCGTCAATGTCGGCTCGGGCGAGCTCG
CCGCGACCGTCACCGCCGCCTGCTTCGACGCCGGGCTGATCATCGAGACCAGCGGCGCGCACGACGAGGTGATCAAGGTG
CTCGCCCCGCTCGTCATCGACGATGCGGTGCTCGGTGCCGGCCTCGACATCCTCGAAAGCAAGATCCGCGAGGCGATGGC
CACCGATTACGCCGTCGCCGCCGAATAA

Upstream 100 bases:

>100_bases
TTCGAGCGCGAGACGCATTTCGCGGGCGCCCACGCCACCGAATATCTGGCCCGCATCGGGCCGTTCGACCGCATGAAAAT
CGACGCAGAACAGGGATAAG

Downstream 100 bases:

>100_bases
ACAGGAGATAACCGACATGATCGTTCGCAACCTCGGCGACATCCGCAAGACCGACCGCAATGTCCGCTCGGACGGCTGGG
CCAGCGCCCGGATGCTGCTC

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MMITTPQPSGNLPDRSIYERRESAVRSYARSMPRQFGKAQGVWMHDDQGGRYLDFLSGCSTLNYGHNHPILKQALLDYIA
ADGIAHGLDLHTDAKQDFLDTFEEVILKPRGLDHRVMFTGPTGTNAVEAAIKLARKVTGREMVIAFTNGFHGMTLGALAC
TGNATKRGGAGVPLSHVAHEPYYDYYGPEVDTAELLEQRLADPSSGLDAPAAILVETVQGEGGLNAASAEWLRRIAGIAK
AHGALLIVDDIQAGCGRTGTFFSFEDMGFTPDIVTLAKSLSGMGLPFALTLLRPELDQWSPGEHNGTFRGNNHAFVTATA
ALRHFWSADDFQRDIGRRAALLETRLARIAAEHGFEVRGRGMMRGVNVGSGELAATVTAACFDAGLIIETSGAHDEVIKV
LAPLVIDDAVLGAGLDILESKIREAMATDYAVAAE

Sequences:

>Translated_435_residues
MMITTPQPSGNLPDRSIYERRESAVRSYARSMPRQFGKAQGVWMHDDQGGRYLDFLSGCSTLNYGHNHPILKQALLDYIA
ADGIAHGLDLHTDAKQDFLDTFEEVILKPRGLDHRVMFTGPTGTNAVEAAIKLARKVTGREMVIAFTNGFHGMTLGALAC
TGNATKRGGAGVPLSHVAHEPYYDYYGPEVDTAELLEQRLADPSSGLDAPAAILVETVQGEGGLNAASAEWLRRIAGIAK
AHGALLIVDDIQAGCGRTGTFFSFEDMGFTPDIVTLAKSLSGMGLPFALTLLRPELDQWSPGEHNGTFRGNNHAFVTATA
ALRHFWSADDFQRDIGRRAALLETRLARIAAEHGFEVRGRGMMRGVNVGSGELAATVTAACFDAGLIIETSGAHDEVIKV
LAPLVIDDAVLGAGLDILESKIREAMATDYAVAAE
>Mature_435_residues
MMITTPQPSGNLPDRSIYERRESAVRSYARSMPRQFGKAQGVWMHDDQGGRYLDFLSGCSTLNYGHNHPILKQALLDYIA
ADGIAHGLDLHTDAKQDFLDTFEEVILKPRGLDHRVMFTGPTGTNAVEAAIKLARKVTGREMVIAFTNGFHGMTLGALAC
TGNATKRGGAGVPLSHVAHEPYYDYYGPEVDTAELLEQRLADPSSGLDAPAAILVETVQGEGGLNAASAEWLRRIAGIAK
AHGALLIVDDIQAGCGRTGTFFSFEDMGFTPDIVTLAKSLSGMGLPFALTLLRPELDQWSPGEHNGTFRGNNHAFVTATA
ALRHFWSADDFQRDIGRRAALLETRLARIAAEHGFEVRGRGMMRGVNVGSGELAATVTAACFDAGLIIETSGAHDEVIKV
LAPLVIDDAVLGAGLDILESKIREAMATDYAVAAE

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=418, Percent_Identity=28.7081339712919, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI284507298, Length=312, Percent_Identity=28.8461538461538, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI13994255, Length=448, Percent_Identity=22.3214285714286, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI37574042, Length=438, Percent_Identity=24.6575342465753, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI24119277, Length=438, Percent_Identity=25.5707762557078, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI226442705, Length=437, Percent_Identity=24.0274599542334, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226442709, Length=340, Percent_Identity=25, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI188536080, Length=301, Percent_Identity=24.2524916943522, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI38679950, Length=301, Percent_Identity=24.2524916943522, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI38679946, Length=301, Percent_Identity=24.2524916943522, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789016, Length=428, Percent_Identity=33.411214953271, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787560, Length=440, Percent_Identity=32.2727272727273, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=29.3670886075949, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI145693181, Length=375, Percent_Identity=28.2666666666667, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=29.7229219143577, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1786991, Length=294, Percent_Identity=30.2721088435374, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=27.2435897435897, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=438, Percent_Identity=26.027397260274, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32564660, Length=424, Percent_Identity=28.5377358490566, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=22.6851851851852, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25144274, Length=294, Percent_Identity=25.1700680272109, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=440, Percent_Identity=24.0909090909091, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=426, Percent_Identity=30.2816901408451, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324432, Length=428, Percent_Identity=27.3364485981308, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=28.125, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=28.8056206088993, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI161085790, Length=425, Percent_Identity=28.7058823529412, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21356575, Length=420, Percent_Identity=25.4761904761905, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281366494, Length=284, Percent_Identity=26.7605633802817, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24667139, Length=284, Percent_Identity=26.7605633802817, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24667143, Length=284, Percent_Identity=26.7605633802817, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46705; Mature: 46705

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMITTPQPSGNLPDRSIYERRESAVRSYARSMPRQFGKAQGVWMHDDQGGRYLDFLSGCS
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHCCC
TLNYGHNHPILKQALLDYIAADGIAHGLDLHTDAKQDFLDTFEEVILKPRGLDHRVMFTG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
PTGTNAVEAAIKLARKVTGREMVIAFTNGFHGMTLGALACTGNATKRGGAGVPLSHVAHE
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHEEECCCCCCCCCCCCCHHHHHCC
PYYDYYGPEVDTAELLEQRLADPSSGLDAPAAILVETVQGEGGLNAASAEWLRRIAGIAK
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHH
AHGALLIVDDIQAGCGRTGTFFSFEDMGFTPDIVTLAKSLSGMGLPFALTLLRPELDQWS
HCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
PGEHNGTFRGNNHAFVTATAALRHFWSADDFQRDIGRRAALLETRLARIAAEHGFEVRGR
CCCCCCCEECCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
GMMRGVNVGSGELAATVTAACFDAGLIIETSGAHDEVIKVLAPLVIDDAVLGAGLDILES
CCEEECCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
KIREAMATDYAVAAE
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MMITTPQPSGNLPDRSIYERRESAVRSYARSMPRQFGKAQGVWMHDDQGGRYLDFLSGCS
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHCCC
TLNYGHNHPILKQALLDYIAADGIAHGLDLHTDAKQDFLDTFEEVILKPRGLDHRVMFTG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
PTGTNAVEAAIKLARKVTGREMVIAFTNGFHGMTLGALACTGNATKRGGAGVPLSHVAHE
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHEEECCCCCCCCCCCCCHHHHHCC
PYYDYYGPEVDTAELLEQRLADPSSGLDAPAAILVETVQGEGGLNAASAEWLRRIAGIAK
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHH
AHGALLIVDDIQAGCGRTGTFFSFEDMGFTPDIVTLAKSLSGMGLPFALTLLRPELDQWS
HCCCEEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
PGEHNGTFRGNNHAFVTATAALRHFWSADDFQRDIGRRAALLETRLARIAAEHGFEVRGR
CCCCCCCEECCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
GMMRGVNVGSGELAATVTAACFDAGLIIETSGAHDEVIKVLAPLVIDDAVLGAGLDILES
CCEEECCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
KIREAMATDYAVAAE
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]