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The map label for this gene is yleA [C]

Identifier: 103488208

GI number: 103488208

Start: 2877476

End: 2878801

Strand: Direct

Name: yleA [C]

Synonym: Sala_2731

Alternate gene names: 103488208

Gene position: 2877476-2878801 (Clockwise)

Preceding gene: 103488207

Following gene: 103488209

Centisome position: 86.02

GC content: 69.68

Gene sequence:

>1326_bases
ATGAACGCAGAACTCGCCGACCGCGTGGAGGTCGTCAATTTTGGTTGCCGGCTCAACATCGCCGAGGGCGAGGCGATTCG
TGCGGCCGTGAAGGCCGCGGGCGCGCGCGATATGATCGTCGTCAACAGCTGCGCGGTGACCGACGAAGCGGTGCGGCAGG
CGCGGCAGGCGGTGCGCCGTGCGCTGCGCGAGCGACCGGACGCCGAGGTGGTGGTGACGGGGTGCGCGGCGGAACTGGAG
GCCGGGCGCTTTGCCGCGATGGGCGCGCGGGTCGTGCGCAATGATGTCAAGGGGCTGATCGGGAGCTATGGAAACACCGT
TTCCCCGCGAAGGCGGGAACCCATCTCCGACGGGCTCGAAATGGCACCGGCTGGTGATGGCCCCCCGCCTTCACGGGGGA
ACAAGGATTTTTTCAGCGGGGTGCGTCCCTTCACCCCCGCCCTCTCTGGCGCAGATCATGCGCGCGCCTTTCTCGGCGTC
CAGACGGGCTGCTCGCACAGCTGCACCTTTTGCGCGACGGTGCTGGCACGCGGCGCCGCGCGGTCGGCGACCGTCGAAAC
GGTCGTCGACGCCGCGCGCACGGCGCTGGGCCGCGGCCAGCGTGAGATCATTCTGACGGGGGTCGATCTTGCCAGCTATG
GCGATGACAGCGGCACCAGCCTGGCTGCGCTTGTCGAGGCCCTGCTCGCGCTCCCGGTCGAGCGCCTGCGCCTCTCCTCG
CTCGACCCCGACCGGATCGACGAGCGCCTGTTCGCGCTGCTGACCGGGGAATCGCGCGTGATGCCGCACGTCCACCTGTC
GTTGCAGGCCGGCGACGACATGGTGCTGACGCGCATGAAGCGCCGCCATCGCCGCGCCGATGCCGTGCGCCTGATCGAAC
GACTGAAGGCGGCGCGCGCGGAGATCGCCATCGGCGCCGACCTGATCGCGGGTTTTCCGACCGAAGATGAAGCGATGTTC
GCGAACTCGCTGGCGCTGATCGACGATTGTGACGTCGTTTTCGGCCATATCTTCCCCTACAGCCCCCGCGCCGGCACCCC
GGCGGCGCGGATGCCGCAGGTCGGCCGCGCCATCGCGCGCGAACGCGCCGCGATGCTGCGCGAAGCCAATGCACGGCGGC
GCCGGGACTGGCTGGACACGCAGGTCGGCCGCACGGCGGCGATGCTCGTGGAGCGCGACGGGAAAACCGGCCATGCCGAA
AACTTTGCCGCGCTGACGCTAACCGCGCCCGCGGCGCCCGGCACCATCATCGACGTGCGCCTGATCGCGCGCGACGGCGA
CCGCATGGTCGCCACTCCCGCAGAAGCAAAGGATATTGCCGCATGA

Upstream 100 bases:

>100_bases
GCGGTGATCTGGTCATCCGCTGGGCACCCGGCGAACCCATCGTGATGAGCGGCGCCGCGACACGCGTGTTCGACGGCGAA
ACCGACTGGGCACAGTTCGG

Downstream 100 bases:

>100_bases
CCGGCAAAAGCTGGAGCGAAAGACTGCTCGGCGGCTTTCGTCGCACCTCCGAACGGCTCGGCGAAAATCTCGCGGGCCTC
ACCGGCAAGGCGCGGCTCGA

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNAELADRVEVVNFGCRLNIAEGEAIRAAVKAAGARDMIVVNSCAVTDEAVRQARQAVRRALRERPDAEVVVTGCAAELE
AGRFAAMGARVVRNDVKGLIGSYGNTVSPRRREPISDGLEMAPAGDGPPPSRGNKDFFSGVRPFTPALSGADHARAFLGV
QTGCSHSCTFCATVLARGAARSATVETVVDAARTALGRGQREIILTGVDLASYGDDSGTSLAALVEALLALPVERLRLSS
LDPDRIDERLFALLTGESRVMPHVHLSLQAGDDMVLTRMKRRHRRADAVRLIERLKAARAEIAIGADLIAGFPTEDEAMF
ANSLALIDDCDVVFGHIFPYSPRAGTPAARMPQVGRAIARERAAMLREANARRRRDWLDTQVGRTAAMLVERDGKTGHAE
NFAALTLTAPAAPGTIIDVRLIARDGDRMVATPAEAKDIAA

Sequences:

>Translated_441_residues
MNAELADRVEVVNFGCRLNIAEGEAIRAAVKAAGARDMIVVNSCAVTDEAVRQARQAVRRALRERPDAEVVVTGCAAELE
AGRFAAMGARVVRNDVKGLIGSYGNTVSPRRREPISDGLEMAPAGDGPPPSRGNKDFFSGVRPFTPALSGADHARAFLGV
QTGCSHSCTFCATVLARGAARSATVETVVDAARTALGRGQREIILTGVDLASYGDDSGTSLAALVEALLALPVERLRLSS
LDPDRIDERLFALLTGESRVMPHVHLSLQAGDDMVLTRMKRRHRRADAVRLIERLKAARAEIAIGADLIAGFPTEDEAMF
ANSLALIDDCDVVFGHIFPYSPRAGTPAARMPQVGRAIARERAAMLREANARRRRDWLDTQVGRTAAMLVERDGKTGHAE
NFAALTLTAPAAPGTIIDVRLIARDGDRMVATPAEAKDIAA
>Mature_441_residues
MNAELADRVEVVNFGCRLNIAEGEAIRAAVKAAGARDMIVVNSCAVTDEAVRQARQAVRRALRERPDAEVVVTGCAAELE
AGRFAAMGARVVRNDVKGLIGSYGNTVSPRRREPISDGLEMAPAGDGPPPSRGNKDFFSGVRPFTPALSGADHARAFLGV
QTGCSHSCTFCATVLARGAARSATVETVVDAARTALGRGQREIILTGVDLASYGDDSGTSLAALVEALLALPVERLRLSS
LDPDRIDERLFALLTGESRVMPHVHLSLQAGDDMVLTRMKRRHRRADAVRLIERLKAARAEIAIGADLIAGFPTEDEAMF
ANSLALIDDCDVVFGHIFPYSPRAGTPAARMPQVGRAIARERAAMLREANARRRRDWLDTQVGRTAAMLVERDGKTGHAE
NFAALTLTAPAAPGTIIDVRLIARDGDRMVATPAEAKDIAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=449, Percent_Identity=26.5033407572383, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI28872782, Length=438, Percent_Identity=21.0045662100457, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI28872784, Length=438, Percent_Identity=21.0045662100457, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1786882, Length=443, Percent_Identity=23.7020316027088, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787057, Length=412, Percent_Identity=24.0291262135922, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71996771, Length=292, Percent_Identity=29.4520547945205, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17553146, Length=382, Percent_Identity=24.6073298429319, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922432, Length=378, Percent_Identity=28.042328042328, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356207, Length=395, Percent_Identity=23.7974683544304, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47072; Mature: 47072

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAELADRVEVVNFGCRLNIAEGEAIRAAVKAAGARDMIVVNSCAVTDEAVRQARQAVRR
CCCCHHHHHHHEECCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
ALRERPDAEVVVTGCAAELEAGRFAAMGARVVRNDVKGLIGSYGNTVSPRRREPISDGLE
HHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCE
MAPAGDGPPPSRGNKDFFSGVRPFTPALSGADHARAFLGVQTGCSHSCTFCATVLARGAA
ECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
RSATVETVVDAARTALGRGQREIILTGVDLASYGDDSGTSLAALVEALLALPVERLRLSS
CHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCC
LDPDRIDERLFALLTGESRVMPHVHLSLQAGDDMVLTRMKRRHRRADAVRLIERLKAARA
CCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAIGADLIAGFPTEDEAMFANSLALIDDCDVVFGHIFPYSPRAGTPAARMPQVGRAIAR
HHHCCHHHHCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCCCCCCCCCHHHCHHHHHHHHH
ERAAMLREANARRRRDWLDTQVGRTAAMLVERDGKTGHAENFAALTLTAPAAPGTIIDVR
HHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEE
LIARDGDRMVATPAEAKDIAA
EEEECCCEEEECCCCHHHCCC
>Mature Secondary Structure
MNAELADRVEVVNFGCRLNIAEGEAIRAAVKAAGARDMIVVNSCAVTDEAVRQARQAVRR
CCCCHHHHHHHEECCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
ALRERPDAEVVVTGCAAELEAGRFAAMGARVVRNDVKGLIGSYGNTVSPRRREPISDGLE
HHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCE
MAPAGDGPPPSRGNKDFFSGVRPFTPALSGADHARAFLGVQTGCSHSCTFCATVLARGAA
ECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
RSATVETVVDAARTALGRGQREIILTGVDLASYGDDSGTSLAALVEALLALPVERLRLSS
CHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCC
LDPDRIDERLFALLTGESRVMPHVHLSLQAGDDMVLTRMKRRHRRADAVRLIERLKAARA
CCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAIGADLIAGFPTEDEAMFANSLALIDDCDVVFGHIFPYSPRAGTPAARMPQVGRAIAR
HHHCCHHHHCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCCCCCCCCCHHHCHHHHHHHHH
ERAAMLREANARRRRDWLDTQVGRTAAMLVERDGKTGHAENFAALTLTAPAAPGTIIDVR
HHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEEE
LIARDGDRMVATPAEAKDIAA
EEEECCCEEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]