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The map label for this gene is hcr [H]

Identifier: 103487947

GI number: 103487947

Start: 2607632

End: 2609509

Strand: Reverse

Name: hcr [H]

Synonym: Sala_2468

Alternate gene names: 103487947

Gene position: 2609509-2607632 (Counterclockwise)

Preceding gene: 103487948

Following gene: 103487946

Centisome position: 78.01

GC content: 65.97

Gene sequence:

>1878_bases
ATGCAGAAATCATTCCGCTTCGGCCTGTGCGTGGCGATGACGTTTCTGACGGCATCGATCGTCCATGCGGAGGACGCCGA
CGAGCATGCCGCCCATCATGGGAGTGCCTCGCCGCCTGGCGGCGTGGCGGTTGGCAGCATGGCGTCATCCGGGATGAAGC
CCGCGGGCGAAATGCAATCGATGATGGGCGAAATGATGGAAGGCGAGCATGGCGGCCGCCGCCAGTCTCCTTTCTTCTCG
CAATTGCTCGCGCTACCGGCACTCGATGACGCGGCGAGGCAAGCCCTGCTGCGGCAAGCCGAGCAACGGTCGCATCGAGG
GCTGATGCTGATCTCCGAGGCCGCCCGCGCAGCCGCGCACGCCGAAACGGCGACCGAGCAAATCGCCGCCGTGCGCAATC
TTCGCGAAGGCAGCGATCTTCTCGATAGCGGTGCGGCTGCCCGGATGGCCCTCGCCGGGACCGGAAAGCCGGCGGGCGCC
GCGATGAACTGGTTCCGCGATCGCCTGTCGATCGAGCCGGACGAGACGCACGCGGCCCATCCTTTCGGCCTGTCTCCCTC
CCACCTGCTGCTGATGCTGTTCCTCCTCTTGCTGAGTACCGGCCTCGCCGCGTTGCAGCTACTTCGTCTCAAGCGCATCC
GTCAGATCGTCGCAGCCAGGAAAGGAACCGCGAAGGTCGCCAACACGCAACCGTCGCCGGCCGCAGCTCCGGAGATGCAG
GCCGCTACGGCCGGAGCGCTCGCGCCAAGCAACGCGCCCGCCCCGGCCGGTGCTTCGCTGCGCAAGCCCCGGCCCTGGTC
CGGACCGCTGCGGGTGACGCGGATCATCCGGGAGACGCCGACCATCAGGACCTTCCGTCTCGCAGATCCCGCAGCCGACC
GGCTGCCTTTCGATTTCCTGCCCGGTCAGTTTCTGCAAATCGAGGTCGAGCCCGAGCCCGGCAAGCGTGCCCGCCGATCC
TACACTATCGCTTCGTCGCCGACGCAGCGGGCCTATGTCGAACTGACGGTGAAGCGCGAGGAGCAGGGAGCGGTGTCCCG
CCACCTGCACGACACGCTCATTGTCGGGGATCTTGTTCGAGCCTCGGGCCCTTTCGGCTCCTTCACCTTCACTGGGACGA
CCGCGGATAGTATCGTGCTCATCGCGGGCGGTGTCGGGATCACGCCGATGATGTCGGTATTGCGCTATCTTACAGACACC
GCCTGGCCGGGCGAGATATTCTTCCTTTATGGCGCTCGGTCCACGGACGAGTTCGTCTTCCGTGACGAAATCGAGCGACT
CGAGCGGCTTCATGACAATCTGCATGTCTTCGCCGCGATGGAGCGCTCGCCAGGGACGGTCTGGCATGGCGCCGTCGGCC
CCCTGACGCGGGACATGCTGCTTTCGGCCGTCCCCGACATCGCGCGCCGCCGCATCCACCTGTGCGGTCCCCCCGCGATG
ATGGCGGCGATGAAGGCGGAGCTCGCCGAGCTCGGCGTGCCGGAAGTGCAACTTCATACCGAAGCCTTTGGGCCCGCATC
GCTGCCCATCGATCCAGTCGACGCGCCCAGCGCGCCCGGCAACGATGCAAGTCGCACGGTACAGCCTCCGTCCGCGCCTT
CCACAAGGATTGCCGAAGCTTCCGTGACGTTCGCTCTGTCGGGTGTGTCCGCCGCCCTGGCTGGCGATCAGACCGTGCTC
GAAGCCGCCGAGGGGGTTGGCGTCGAGATACCCTATTCCTGCCGCACCGGAGACTGCGGACTATGCGTCACCAAGCTGCT
CGACGGTGAAGTCACGATGGCGAACGAAGCGGGCCTGGCGCCGGAAGACAAGGCGAACGGCTATATATTGGCTTGCCAGG
CCAAAGGCAGCGGCAAGCCGATCGTGGTTGAAGCCTGA

Upstream 100 bases:

>100_bases
GCGGGGCAAGGCAATATGCAGCCCGCGGATCAGACCACGACCGATCAGTCGGCGCCGATGAAGCATATGTAAGCAGATTC
GCCGGGCGGGGTGACCAAAG

Downstream 100 bases:

>100_bases
TGCGCGAACGCGGCGACATATTGATGGTGCTTCTGGTGGGGTTCATTCTGGTCTTTCCGGCCGGATTTCTCGTTCACGCA
TCCCCACGCTTCCCCGGTAG

Product: oxidoreductase FAD-binding region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MQKSFRFGLCVAMTFLTASIVHAEDADEHAAHHGSASPPGGVAVGSMASSGMKPAGEMQSMMGEMMEGEHGGRRQSPFFS
QLLALPALDDAARQALLRQAEQRSHRGLMLISEAARAAAHAETATEQIAAVRNLREGSDLLDSGAAARMALAGTGKPAGA
AMNWFRDRLSIEPDETHAAHPFGLSPSHLLLMLFLLLLSTGLAALQLLRLKRIRQIVAARKGTAKVANTQPSPAAAPEMQ
AATAGALAPSNAPAPAGASLRKPRPWSGPLRVTRIIRETPTIRTFRLADPAADRLPFDFLPGQFLQIEVEPEPGKRARRS
YTIASSPTQRAYVELTVKREEQGAVSRHLHDTLIVGDLVRASGPFGSFTFTGTTADSIVLIAGGVGITPMMSVLRYLTDT
AWPGEIFFLYGARSTDEFVFRDEIERLERLHDNLHVFAAMERSPGTVWHGAVGPLTRDMLLSAVPDIARRRIHLCGPPAM
MAAMKAELAELGVPEVQLHTEAFGPASLPIDPVDAPSAPGNDASRTVQPPSAPSTRIAEASVTFALSGVSAALAGDQTVL
EAAEGVGVEIPYSCRTGDCGLCVTKLLDGEVTMANEAGLAPEDKANGYILACQAKGSGKPIVVEA

Sequences:

>Translated_625_residues
MQKSFRFGLCVAMTFLTASIVHAEDADEHAAHHGSASPPGGVAVGSMASSGMKPAGEMQSMMGEMMEGEHGGRRQSPFFS
QLLALPALDDAARQALLRQAEQRSHRGLMLISEAARAAAHAETATEQIAAVRNLREGSDLLDSGAAARMALAGTGKPAGA
AMNWFRDRLSIEPDETHAAHPFGLSPSHLLLMLFLLLLSTGLAALQLLRLKRIRQIVAARKGTAKVANTQPSPAAAPEMQ
AATAGALAPSNAPAPAGASLRKPRPWSGPLRVTRIIRETPTIRTFRLADPAADRLPFDFLPGQFLQIEVEPEPGKRARRS
YTIASSPTQRAYVELTVKREEQGAVSRHLHDTLIVGDLVRASGPFGSFTFTGTTADSIVLIAGGVGITPMMSVLRYLTDT
AWPGEIFFLYGARSTDEFVFRDEIERLERLHDNLHVFAAMERSPGTVWHGAVGPLTRDMLLSAVPDIARRRIHLCGPPAM
MAAMKAELAELGVPEVQLHTEAFGPASLPIDPVDAPSAPGNDASRTVQPPSAPSTRIAEASVTFALSGVSAALAGDQTVL
EAAEGVGVEIPYSCRTGDCGLCVTKLLDGEVTMANEAGLAPEDKANGYILACQAKGSGKPIVVEA
>Mature_625_residues
MQKSFRFGLCVAMTFLTASIVHAEDADEHAAHHGSASPPGGVAVGSMASSGMKPAGEMQSMMGEMMEGEHGGRRQSPFFS
QLLALPALDDAARQALLRQAEQRSHRGLMLISEAARAAAHAETATEQIAAVRNLREGSDLLDSGAAARMALAGTGKPAGA
AMNWFRDRLSIEPDETHAAHPFGLSPSHLLLMLFLLLLSTGLAALQLLRLKRIRQIVAARKGTAKVANTQPSPAAAPEMQ
AATAGALAPSNAPAPAGASLRKPRPWSGPLRVTRIIRETPTIRTFRLADPAADRLPFDFLPGQFLQIEVEPEPGKRARRS
YTIASSPTQRAYVELTVKREEQGAVSRHLHDTLIVGDLVRASGPFGSFTFTGTTADSIVLIAGGVGITPMMSVLRYLTDT
AWPGEIFFLYGARSTDEFVFRDEIERLERLHDNLHVFAAMERSPGTVWHGAVGPLTRDMLLSAVPDIARRRIHLCGPPAM
MAAMKAELAELGVPEVQLHTEAFGPASLPIDPVDAPSAPGNDASRTVQPPSAPSTRIAEASVTFALSGVSAALAGDQTVL
EAAEGVGVEIPYSCRTGDCGLCVTKLLDGEVTMANEAGLAPEDKANGYILACQAKGSGKPIVVEA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI47778923, Length=250, Percent_Identity=26.4, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI49574502, Length=211, Percent_Identity=28.9099526066351, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1787098, Length=359, Percent_Identity=30.08356545961, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1787658, Length=373, Percent_Identity=27.3458445040214, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788903, Length=251, Percent_Identity=30.2788844621514, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788104, Length=363, Percent_Identity=25.3443526170799, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17563928, Length=233, Percent_Identity=29.6137339055794, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17563926, Length=242, Percent_Identity=28.099173553719, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323552, Length=239, Percent_Identity=29.2887029288703, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323510, Length=234, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322146, Length=234, Percent_Identity=27.3504273504274, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321673, Length=217, Percent_Identity=26.2672811059908, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322699, Length=225, Percent_Identity=25.7777777777778, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 66174; Mature: 66174

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSFRFGLCVAMTFLTASIVHAEDADEHAAHHGSASPPGGVAVGSMASSGMKPAGEMQS
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEECCHHHCCCCCHHHHHH
MMGEMMEGEHGGRRQSPFFSQLLALPALDDAARQALLRQAEQRSHRGLMLISEAARAAAH
HHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
AETATEQIAAVRNLREGSDLLDSGAAARMALAGTGKPAGAAMNWFRDRLSIEPDETHAAH
HHHHHHHHHHHHHHHCCHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCC
PFGLSPSHLLLMLFLLLLSTGLAALQLLRLKRIRQIVAARKGTAKVANTQPSPAAAPEMQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHH
AATAGALAPSNAPAPAGASLRKPRPWSGPLRVTRIIRETPTIRTFRLADPAADRLPFDFL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCC
PGQFLQIEVEPEPGKRARRSYTIASSPTQRAYVELTVKREEQGAVSRHLHDTLIVGDLVR
CCCEEEEEECCCCCHHHHHEEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
ASGPFGSFTFTGTTADSIVLIAGGVGITPMMSVLRYLTDTAWPGEIFFLYGARSTDEFVF
CCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHH
RDEIERLERLHDNLHVFAAMERSPGTVWHGAVGPLTRDMLLSAVPDIARRRIHLCGPPAM
HHHHHHHHHHHCCEEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEECCCHHH
MAAMKAELAELGVPEVQLHTEAFGPASLPIDPVDAPSAPGNDASRTVQPPSAPSTRIAEA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHH
SVTFALSGVSAALAGDQTVLEAAEGVGVEIPYSCRTGDCGLCVTKLLDGEVTMANEAGLA
EEEEEECCCHHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHCCCEEECCCCCCC
PEDKANGYILACQAKGSGKPIVVEA
CCCCCCCEEEEEEECCCCCCEEEEC
>Mature Secondary Structure
MQKSFRFGLCVAMTFLTASIVHAEDADEHAAHHGSASPPGGVAVGSMASSGMKPAGEMQS
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEECCHHHCCCCCHHHHHH
MMGEMMEGEHGGRRQSPFFSQLLALPALDDAARQALLRQAEQRSHRGLMLISEAARAAAH
HHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
AETATEQIAAVRNLREGSDLLDSGAAARMALAGTGKPAGAAMNWFRDRLSIEPDETHAAH
HHHHHHHHHHHHHHHCCHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCC
PFGLSPSHLLLMLFLLLLSTGLAALQLLRLKRIRQIVAARKGTAKVANTQPSPAAAPEMQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHH
AATAGALAPSNAPAPAGASLRKPRPWSGPLRVTRIIRETPTIRTFRLADPAADRLPFDFL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCC
PGQFLQIEVEPEPGKRARRSYTIASSPTQRAYVELTVKREEQGAVSRHLHDTLIVGDLVR
CCCEEEEEECCCCCHHHHHEEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
ASGPFGSFTFTGTTADSIVLIAGGVGITPMMSVLRYLTDTAWPGEIFFLYGARSTDEFVF
CCCCCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHH
RDEIERLERLHDNLHVFAAMERSPGTVWHGAVGPLTRDMLLSAVPDIARRRIHLCGPPAM
HHHHHHHHHHHCCEEEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEECCCHHH
MAAMKAELAELGVPEVQLHTEAFGPASLPIDPVDAPSAPGNDASRTVQPPSAPSTRIAEA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHH
SVTFALSGVSAALAGDQTVLEAAEGVGVEIPYSCRTGDCGLCVTKLLDGEVTMANEAGLA
EEEEEECCCHHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHCCCEEECCCCCCC
PEDKANGYILACQAKGSGKPIVVEA
CCCCCCCEEEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]