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The map label for this gene is czcC [H]

Identifier: 103487926

GI number: 103487926

Start: 2584208

End: 2585479

Strand: Direct

Name: czcC [H]

Synonym: Sala_2447

Alternate gene names: 103487926

Gene position: 2584208-2585479 (Clockwise)

Preceding gene: 103487925

Following gene: 103487927

Centisome position: 77.25

GC content: 70.2

Gene sequence:

>1272_bases
ATGTACAGGATCGTTGTTGCCCTCGTGGCAGCCACATCGTGCGTTGCGATAGCGCAGGCACAGGAGGTCGGCACCGAAAG
CCGGCAGATATCAGGACCGCTCCTGACGCTCGACGAGGCGGTTGCGCTCGCGGGCGGCAGCGCGCCCGCGGCGGAAGCCG
CAGCGGCGGACGTTGATGCCGCAAGCGCAGCCCGCCGAGTCGCGGGGCTGCGCCCCAACCCAGCGCTTTCGGTCGAAGTC
GAGAATTTCGTCGGCACCGGGCCCTATAATGGCGTCAATGGCGCCGATATCACGGCAAGCGTCGCGATCCCGCTCGAACT
CGGCGGCAAGCGGCAGGCCCGGATCGCGGTTGCCGATGCGGCGGCGCACCGCGCGCAAATCGCGCAGGCGATTGCGCAGG
CCGATATCCGGTTCCAGGTCACCGAACTCTATATCCAGGCCTCGGCCGCCGAAGTGCGTGTCGCGATTGCCGAGGACCAA
TATCGTATCGCCGGCGACACGGCGCGCGCCGCGACCATAAGAGTGCAAGCGGGGCGCGCCTCGCCGCTCGAACAAGAACG
CGCCGAAGTCGCGCGCCTGACCGCCGAAACCGAGGCCGAGAAAGCGCGCCGCCTCGCCGATGCCGCGCGCGCCAGTCTCG
CGCGCCGCATTGGCCGCCCGGTCACCGGCCCGCTCGATGTCGCGGTACTCGGCGGCCCCGGAAGCGGCACCATGGGTCCG
CCCCGCCCTGTATCGGCGGCTGGCACGCTCGCGCTGGCGGCGGCCGATGCCGACCTCGCCACCGCGGATGCCGGCGTCGA
ACTGGCGCGTTCGCAGCGCGTGCCCGATCTTACCGTCGGGCCGGGCGTTCGCCGGCTCGAAGCCACCAACGATGTCGCTG
CGGTGTTCAGCGTCTCGGTGCCGCTGCCGCTGTTCAACAACGGACGCGCCGCGGTCGACCAGGCGAATGCCGAACGGCGG
CGTGCCGACGCGCAGCGCCGCGTCACCGCGCTCGATATCGAGCAGAAGATCAGCGACGCCGAAGTCGAGGCTGCCAATGC
GGCCGCGGCGGCGCGCGTCGCGAGCGGCCCCGCTCTGTCCTCGGCCATGGAAGCCGCGCGCATTGCGCGCATCGGCTACC
GCGAGGGCAAGTTCGGACAGCTCGAACTGCTCGATGCCGAACGGACGCTGACCGAGATGCGCTCCGCGTCGATCGAAGCC
CTCGCCTCCTATCAACTCGCCAAGGCCCGGTTGGAACGCCTGACGGCTCCCGCGCCGCTCGAAGGAAATTGA

Upstream 100 bases:

>100_bases
CGCGCGTCCTGCCGCCCCTTCTCGACCCGCCCCTCGCCTGACGTCTTGACGGGCTCGCGCATTCGCGCGGCGATCTATCG
GCTCAATCGAGGATGGAATT

Downstream 100 bases:

>100_bases
CCCGATGACTATCACTATCAACCGAAAGCTGCTGCTCGCCGCGACGCTGCCGCTGTTCCTCGCCGCCTGCGGTGGCGGCG
AGACCGCCAAACCCGCCGAC

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MYRIVVALVAATSCVAIAQAQEVGTESRQISGPLLTLDEAVALAGGSAPAAEAAAADVDAASAARRVAGLRPNPALSVEV
ENFVGTGPYNGVNGADITASVAIPLELGGKRQARIAVADAAAHRAQIAQAIAQADIRFQVTELYIQASAAEVRVAIAEDQ
YRIAGDTARAATIRVQAGRASPLEQERAEVARLTAETEAEKARRLADAARASLARRIGRPVTGPLDVAVLGGPGSGTMGP
PRPVSAAGTLALAAADADLATADAGVELARSQRVPDLTVGPGVRRLEATNDVAAVFSVSVPLPLFNNGRAAVDQANAERR
RADAQRRVTALDIEQKISDAEVEAANAAAAARVASGPALSSAMEAARIARIGYREGKFGQLELLDAERTLTEMRSASIEA
LASYQLAKARLERLTAPAPLEGN

Sequences:

>Translated_423_residues
MYRIVVALVAATSCVAIAQAQEVGTESRQISGPLLTLDEAVALAGGSAPAAEAAAADVDAASAARRVAGLRPNPALSVEV
ENFVGTGPYNGVNGADITASVAIPLELGGKRQARIAVADAAAHRAQIAQAIAQADIRFQVTELYIQASAAEVRVAIAEDQ
YRIAGDTARAATIRVQAGRASPLEQERAEVARLTAETEAEKARRLADAARASLARRIGRPVTGPLDVAVLGGPGSGTMGP
PRPVSAAGTLALAAADADLATADAGVELARSQRVPDLTVGPGVRRLEATNDVAAVFSVSVPLPLFNNGRAAVDQANAERR
RADAQRRVTALDIEQKISDAEVEAANAAAAARVASGPALSSAMEAARIARIGYREGKFGQLELLDAERTLTEMRSASIEA
LASYQLAKARLERLTAPAPLEGN
>Mature_423_residues
MYRIVVALVAATSCVAIAQAQEVGTESRQISGPLLTLDEAVALAGGSAPAAEAAAADVDAASAARRVAGLRPNPALSVEV
ENFVGTGPYNGVNGADITASVAIPLELGGKRQARIAVADAAAHRAQIAQAIAQADIRFQVTELYIQASAAEVRVAIAEDQ
YRIAGDTARAATIRVQAGRASPLEQERAEVARLTAETEAEKARRLADAARASLARRIGRPVTGPLDVAVLGGPGSGTMGP
PRPVSAAGTLALAAADADLATADAGVELARSQRVPDLTVGPGVRRLEATNDVAAVFSVSVPLPLFNNGRAAVDQANAERR
RADAQRRVTALDIEQKISDAEVEAANAAAAARVASGPALSSAMEAARIARIGYREGKFGQLELLDAERTLTEMRSASIEA
LASYQLAKARLERLTAPAPLEGN

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 43516; Mature: 43516

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIVVALVAATSCVAIAQAQEVGTESRQISGPLLTLDEAVALAGGSAPAAEAAAADVDA
CHHHHEEHHHHHHHHHHHHHHHCCCCCHHCCCCEEEHHHHHHHCCCCCCCHHHHHHCCHH
ASAARRVAGLRPNPALSVEVENFVGTGPYNGVNGADITASVAIPLELGGKRQARIAVADA
HHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEHHH
AAHRAQIAQAIAQADIRFQVTELYIQASAAEVRVAIAEDQYRIAGDTARAATIRVQAGRA
HHHHHHHHHHHHHHCCEEEEEEEEEEECCCEEEEEEECCCEEEECCCCEEEEEEEECCCC
SPLEQERAEVARLTAETEAEKARRLADAARASLARRIGRPVTGPLDVAVLGGPGSGTMGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
PRPVSAAGTLALAAADADLATADAGVELARSQRVPDLTVGPGVRRLEATNDVAAVFSVSV
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEEEEC
PLPLFNNGRAAVDQANAERRRADAQRRVTALDIEQKISDAEVEAANAAAAARVASGPALS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCHHHHHHHHHHHHHHCCCCHHH
SAMEAARIARIGYREGKFGQLELLDAERTLTEMRSASIEALASYQLAKARLERLTAPAPL
HHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGN
CCC
>Mature Secondary Structure
MYRIVVALVAATSCVAIAQAQEVGTESRQISGPLLTLDEAVALAGGSAPAAEAAAADVDA
CHHHHEEHHHHHHHHHHHHHHHCCCCCHHCCCCEEEHHHHHHHCCCCCCCHHHHHHCCHH
ASAARRVAGLRPNPALSVEVENFVGTGPYNGVNGADITASVAIPLELGGKRQARIAVADA
HHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEHHH
AAHRAQIAQAIAQADIRFQVTELYIQASAAEVRVAIAEDQYRIAGDTARAATIRVQAGRA
HHHHHHHHHHHHHHCCEEEEEEEEEEECCCEEEEEEECCCEEEECCCCEEEEEEEECCCC
SPLEQERAEVARLTAETEAEKARRLADAARASLARRIGRPVTGPLDVAVLGGPGSGTMGP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
PRPVSAAGTLALAAADADLATADAGVELARSQRVPDLTVGPGVRRLEATNDVAAVFSVSV
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEEEEC
PLPLFNNGRAAVDQANAERRRADAQRRVTALDIEQKISDAEVEAANAAAAARVASGPALS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCHHHHHHHHHHHHHHCCCCHHH
SAMEAARIARIGYREGKFGQLELLDAERTLTEMRSASIEALASYQLAKARLERLTAPAPL
HHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]