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The map label for this gene is atpA

Identifier: 103487767

GI number: 103487767

Start: 2410077

End: 2411606

Strand: Direct

Name: atpA

Synonym: Sala_2286

Alternate gene names: 103487767

Gene position: 2410077-2411606 (Clockwise)

Preceding gene: 103487765

Following gene: 103487768

Centisome position: 72.05

GC content: 64.77

Gene sequence:

>1530_bases
ATGGAAATCCGCGCCGCTGAAATCAGCAAGGTCATCAAGGACCAGATCGCCAATTTCGGAACCGACGCCACGGTCACCGA
GATCGGTTCGGTGCTCTCGGTCGGCGACGGCATCGCCCGCGTCCACGGCCTCGACAATGTCCAGGCCGGTGAAATGGTCG
AATTCGCCAATGGCGTGAAGGGCATGGCGCTCAACCTCGAAGCCGACAATGTCGGCATCGTGATCTTCGGCAGCGACGCC
GCGATCAAGGAAGGCGACCAGGTCAAGCGCACCGGCACGATCGTCGACGTCCCGGTCGGCAAGGGGCTGCTCGGCCGCGT
CGTCGATGGCCTCGGCAATCCGATCGACGGCAAGGGCCCGATCAAGGCCGACAAGCGGATGCGCGTCGAGGTGAAGGCGC
CGGGCATCATCCCGCGCACCTCGGTCCACGAACCCGTGCAGACCGGCCTCAAGGCACTGGACGCGCTCGTCCCCGTCGGC
CGCGGCCAGCGCGAGCTGATCATCGGCGACCGCCAGACCGGCAAGACCGCCGTGGCGATCGACACCTTCATCAACCAGAA
GGCCGCCAACGCGGGCGATGACGAGTCGAAGAAGCTCTATTGCATCTATGTCGCCGTCGGCCAGAAGCGTTCGACCGTCG
CGCAGATCGTCCGCCAGCTCGAAGAAAATGGCGCGATGGAATATTCGATCGTCGTCGCCGCGACCGCGTCGGAACCCGCG
CCGCTCCAGTTCCTCGCGCCCTACACCGGCTGCACGATGGGCGAGTTCTTCCGCGACAACGGTATGCACGCCGTGATCGT
CTATGACGATCTGTCGAAGCAGGCCGTCGCCTATCGCCAGATGTCGCTGCTGCTGCGCCGCCCGCCGGGCCGCGAAGCCT
ATCCGGGCGACGTTTTCTATCTGCACAGCCGCCTGCTCGAGCGCGCGGCCAAGATGAACAGCGACAATGGTTCGGGCTCG
CTCACCGCGCTGCCGATCATCGAAACGCAGGCGGGCGACGTGTCGGCGTACATCCCGACCAACGTGATTTCGATCACCGA
CGGCCAGATCTTCCTCGAAACCAACCTGTTCAACGCCGGTATCCGCCCGGCGATCAACGTCGGCCTGTCGGTGAGCCGCG
TCGGCTCGGCCGCGCAGACCAAGGCGATGAAGAAGGTGTCGGGCTCGATCAAGCTCGAACTCGCGCAATATCGCGAAATG
GAAGCCTTTGCGCAGTTCGGCTCGGACCTCGACGCCTCGACGCAGAAACTGCTGGGCCGCGGCGCGCGCCTGACCCAGCT
TTTGAAGCAGCCGCAGTTCCAGCCGATGCCGTTCGAGGAACAGACCGCGTCGATCTTCGCGGGCACCAACGGCTATCTCG
ACACTGTCGCGACCACCGACGTGTCGCGCTACGAAGCGGCGATGCTCGCCTATCTGCGCAGCGACCACCCGCAAGTGCTG
GCGGCGATCCGCGACAGCAAGGATCTGGGCGACGACACGAAGAAGGCGCTGGTCGCCGCGCTCGACGCCTTCGCCAAGAT
TTTCGCATAA

Upstream 100 bases:

>100_bases
GCTGATCGACGGCAGCATCCGTACCCGTCTCAATAGCTTCGCGCAGGCGATGAAGGGCTGAAAGCCCGTACGCCCTATGT
GTTCGATGAAAGGCTGAATA

Downstream 100 bases:

>100_bases
TCGTCACCCCGGCGAAAGCCGGGGTCTCGACGGTGAGATCCCGGCCTTCGCCGGGATGACAGATTAAAGGGTAAAGACGG
GACTTATGGCCAGTCTGAAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MEIRAAEISKVIKDQIANFGTDATVTEIGSVLSVGDGIARVHGLDNVQAGEMVEFANGVKGMALNLEADNVGIVIFGSDA
AIKEGDQVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGPIKADKRMRVEVKAPGIIPRTSVHEPVQTGLKALDALVPVG
RGQRELIIGDRQTGKTAVAIDTFINQKAANAGDDESKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
PLQFLAPYTGCTMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNSDNGSGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNAGIRPAINVGLSVSRVGSAAQTKAMKKVSGSIKLELAQYREM
EAFAQFGSDLDASTQKLLGRGARLTQLLKQPQFQPMPFEEQTASIFAGTNGYLDTVATTDVSRYEAAMLAYLRSDHPQVL
AAIRDSKDLGDDTKKALVAALDAFAKIFA

Sequences:

>Translated_509_residues
MEIRAAEISKVIKDQIANFGTDATVTEIGSVLSVGDGIARVHGLDNVQAGEMVEFANGVKGMALNLEADNVGIVIFGSDA
AIKEGDQVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGPIKADKRMRVEVKAPGIIPRTSVHEPVQTGLKALDALVPVG
RGQRELIIGDRQTGKTAVAIDTFINQKAANAGDDESKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
PLQFLAPYTGCTMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNSDNGSGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNAGIRPAINVGLSVSRVGSAAQTKAMKKVSGSIKLELAQYREM
EAFAQFGSDLDASTQKLLGRGARLTQLLKQPQFQPMPFEEQTASIFAGTNGYLDTVATTDVSRYEAAMLAYLRSDHPQVL
AAIRDSKDLGDDTKKALVAALDAFAKIFA
>Mature_509_residues
MEIRAAEISKVIKDQIANFGTDATVTEIGSVLSVGDGIARVHGLDNVQAGEMVEFANGVKGMALNLEADNVGIVIFGSDA
AIKEGDQVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGPIKADKRMRVEVKAPGIIPRTSVHEPVQTGLKALDALVPVG
RGQRELIIGDRQTGKTAVAIDTFINQKAANAGDDESKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
PLQFLAPYTGCTMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNSDNGSGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNAGIRPAINVGLSVSRVGSAAQTKAMKKVSGSIKLELAQYREM
EAFAQFGSDLDASTQKLLGRGARLTQLLKQPQFQPMPFEEQTASIFAGTNGYLDTVATTDVSRYEAAMLAYLRSDHPQVL
AAIRDSKDLGDDTKKALVAALDAFAKIFA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=479, Percent_Identity=72.651356993737, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=479, Percent_Identity=72.651356993737, Blast_Score=726, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=28.476821192053, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI19913426, Length=390, Percent_Identity=26.4102564102564, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI32189394, Length=390, Percent_Identity=25.1282051282051, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=515, Percent_Identity=57.6699029126214, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1790170, Length=441, Percent_Identity=24.4897959183673, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788251, Length=352, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=503, Percent_Identity=70.5765407554672, Blast_Score=729, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=503, Percent_Identity=70.5765407554672, Blast_Score=727, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=503, Percent_Identity=65.2087475149105, Blast_Score=659, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570191, Length=329, Percent_Identity=27.0516717325228, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=383, Percent_Identity=26.6318537859008, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=402, Percent_Identity=24.6268656716418, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988068, Length=75, Percent_Identity=56, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=68, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17565854, Length=260, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=502, Percent_Identity=69.7211155378486, Blast_Score=729, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=346, Percent_Identity=27.4566473988439, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6322581, Length=409, Percent_Identity=26.8948655256724, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320016, Length=156, Percent_Identity=30.7692307692308, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24658560, Length=480, Percent_Identity=71.25, Blast_Score=712, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=28.5245901639344, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=28.5245901639344, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=28.5245901639344, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24638766, Length=391, Percent_Identity=25.0639386189258, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28574560, Length=409, Percent_Identity=24.9388753056235, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129479, Length=269, Percent_Identity=28.996282527881, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24583988, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583986, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583984, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583992, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_SPHAL (Q1GQS7)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617328.1
- ProteinModelPortal:   Q1GQS7
- SMR:   Q1GQS7
- GeneID:   4080743
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2286
- NMPDR:   fig|317655.9.peg.2209
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   SALA317655:SALA_2286-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54435; Mature: 54435

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRAAEISKVIKDQIANFGTDATVTEIGSVLSVGDGIARVHGLDNVQAGEMVEFANGVK
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHCCCC
GMALNLEADNVGIVIFGSDAAIKEGDQVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCCHHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCC
IKADKRMRVEVKAPGIIPRTSVHEPVQTGLKALDALVPVGRGQRELIIGDRQTGKTAVAI
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTFINQKAANAGDDESKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
HHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
PLQFLAPYTGCTMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CEEEECCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMNSDNGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNAG
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEECCCCCC
IRPAINVGLSVSRVGSAAQTKAMKKVSGSIKLELAQYREMEAFAQFGSDLDASTQKLLGR
CCCHHHCCEEHHHHCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHCC
GARLTQLLKQPQFQPMPFEEQTASIFAGTNGYLDTVATTDVSRYEAAMLAYLRSDHPQVL
CHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEECHHHCCHHHHHHHHHHHHHCCCHHHH
AAIRDSKDLGDDTKKALVAALDAFAKIFA
HHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIRAAEISKVIKDQIANFGTDATVTEIGSVLSVGDGIARVHGLDNVQAGEMVEFANGVK
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHCCCC
GMALNLEADNVGIVIFGSDAAIKEGDQVKRTGTIVDVPVGKGLLGRVVDGLGNPIDGKGP
CEEEEEECCCEEEEEECCCCCCCCCCCHHHCCCEEEECCCCCHHHHHHHHCCCCCCCCCC
IKADKRMRVEVKAPGIIPRTSVHEPVQTGLKALDALVPVGRGQRELIIGDRQTGKTAVAI
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTFINQKAANAGDDESKKLYCIYVAVGQKRSTVAQIVRQLEENGAMEYSIVVAATASEPA
HHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
PLQFLAPYTGCTMGEFFRDNGMHAVIVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFY
CEEEECCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMNSDNGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETNLFNAG
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEECCCCCC
IRPAINVGLSVSRVGSAAQTKAMKKVSGSIKLELAQYREMEAFAQFGSDLDASTQKLLGR
CCCHHHCCEEHHHHCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHCC
GARLTQLLKQPQFQPMPFEEQTASIFAGTNGYLDTVATTDVSRYEAAMLAYLRSDHPQVL
CHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEECHHHCCHHHHHHHHHHHHHCCCHHHH
AAIRDSKDLGDDTKKALVAALDAFAKIFA
HHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA