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The map label for this gene is fabD [H]

Identifier: 103487381

GI number: 103487381

Start: 1996768

End: 1997706

Strand: Reverse

Name: fabD [H]

Synonym: Sala_1897

Alternate gene names: 103487381

Gene position: 1997706-1996768 (Counterclockwise)

Preceding gene: 103487382

Following gene: 103487380

Centisome position: 59.72

GC content: 68.26

Gene sequence:

>939_bases
ATGCGCGCATTCATCTTTCCGGGACAGGGCAGCCAGTCGGTCGGCATGGGCAGGGCGCTCGCCGACGCATCGAGTCACGC
CCGCGAGGTGTTCCAGGAGGTCGACGACGCGCTCGGCCAGAAGCTGTTCCGGCTGATGAGCGAAGGGCCGGAGGATCAGC
TGACGCTCACCGAAAACGCCCAGCCCGCGATCATGGCGAACGCGATCGCCACCTTGCGCGTGCTGGAGAAGGAAGGCGGC
GTGACGCTTGCGGCCAAGGCCGACTATGTCGCGGGCCACAGCCTCGGTGAATATAGTGCGCTCTGCGCCGCGGGGGCGTT
CGATCTTGCGACCGCTGCGCGGCTGCTCAAGACGCGCGGGCAGGCGATGCAGGCGGCCGTGCCCGTCGGCGTCGGCGCGA
TGGCGGCGCTGCTCGGCGCCGACATCGAGACCGCTCAGAGGCTCGCGGATGCGGCGGCGGAGGGCGAGATATGCACCGTC
GCCAACGACAATGATCCGTTGCAGGTCGTCATCTCGGGCCACAAGGGCGCGGTCGAGCGCGCGGTCGCGCTGGTCAAGGA
CTATGGCATCAAGCGCGGCGTGCTGTTGCCTGTCTCGGCGCCCTTCCACTGCCCGCTGATGCAGCCCGCCGCCGACGCGA
TGGCCGAGGCGCTTGGCGCCAATCCCCCCGCGGCGCCGCTGGTCCCCGTCGTCGCCAATGTCACCGCCAGCCCGGTGAGC
GATGCCGACACGATCCGTGACCTGCTGGTCCAGCAAGTTACCGGCCGCGTCCGCTGGCGTGAGAGCGTCGGTGCGATGGA
GGATGTCGGGGTCACGCACTTCGTCGAGTTCGGCGGCAAGGTGCTATCCCCGATGGTCAAGCGCAGCGCATCGGGCGAGG
TCGAGACGGTCAGCCTGATCTCGATGGACGACATCGAGGCACTGCTCAAAACGCTTTAA

Upstream 100 bases:

>100_bases
CCCCGCGAAGGCGGGGGCCGTTGTCGGCCCTGCGCCGATGGCGCGGAACAAAACTCCAGCGGCCCCCGCCTTCGCGGGGG
CGACGATAAAGGGCAGGGTC

Downstream 100 bases:

>100_bases
GATTCATGTTTCAGGAGACCAGGAATGTTCGATCTCACCGGTATGACCGCCCTCGTCACGGGCGCGAGCGGCGGCATCGG
TTCGGCCATCGCGCAGGCAC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRAFIFPGQGSQSVGMGRALADASSHAREVFQEVDDALGQKLFRLMSEGPEDQLTLTENAQPAIMANAIATLRVLEKEGG
VTLAAKADYVAGHSLGEYSALCAAGAFDLATAARLLKTRGQAMQAAVPVGVGAMAALLGADIETAQRLADAAAEGEICTV
ANDNDPLQVVISGHKGAVERAVALVKDYGIKRGVLLPVSAPFHCPLMQPAADAMAEALGANPPAAPLVPVVANVTASPVS
DADTIRDLLVQQVTGRVRWRESVGAMEDVGVTHFVEFGGKVLSPMVKRSASGEVETVSLISMDDIEALLKTL

Sequences:

>Translated_312_residues
MRAFIFPGQGSQSVGMGRALADASSHAREVFQEVDDALGQKLFRLMSEGPEDQLTLTENAQPAIMANAIATLRVLEKEGG
VTLAAKADYVAGHSLGEYSALCAAGAFDLATAARLLKTRGQAMQAAVPVGVGAMAALLGADIETAQRLADAAAEGEICTV
ANDNDPLQVVISGHKGAVERAVALVKDYGIKRGVLLPVSAPFHCPLMQPAADAMAEALGANPPAAPLVPVVANVTASPVS
DADTIRDLLVQQVTGRVRWRESVGAMEDVGVTHFVEFGGKVLSPMVKRSASGEVETVSLISMDDIEALLKTL
>Mature_312_residues
MRAFIFPGQGSQSVGMGRALADASSHAREVFQEVDDALGQKLFRLMSEGPEDQLTLTENAQPAIMANAIATLRVLEKEGG
VTLAAKADYVAGHSLGEYSALCAAGAFDLATAARLLKTRGQAMQAAVPVGVGAMAALLGADIETAQRLADAAAEGEICTV
ANDNDPLQVVISGHKGAVERAVALVKDYGIKRGVLLPVSAPFHCPLMQPAADAMAEALGANPPAAPLVPVVANVTASPVS
DADTIRDLLVQQVTGRVRWRESVGAMEDVGVTHFVEFGGKVLSPMVKRSASGEVETVSLISMDDIEALLKTL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=275, Percent_Identity=34.1818181818182, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1787334, Length=287, Percent_Identity=47.7351916376307, Blast_Score=226, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71984332, Length=266, Percent_Identity=30.8270676691729, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=297, Percent_Identity=28.2828282828283, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24665753, Length=272, Percent_Identity=34.1911764705882, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32380; Mature: 32380

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFIFPGQGSQSVGMGRALADASSHAREVFQEVDDALGQKLFRLMSEGPEDQLTLTENA
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAIMANAIATLRVLEKEGGVTLAAKADYVAGHSLGEYSALCAAGAFDLATAARLLKTRG
CCHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHC
QAMQAAVPVGVGAMAALLGADIETAQRLADAAAEGEICTVANDNDPLQVVISGHKGAVER
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCHHHHH
AVALVKDYGIKRGVLLPVSAPFHCPLMQPAADAMAEALGANPPAAPLVPVVANVTASPVS
HHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
DADTIRDLLVQQVTGRVRWRESVGAMEDVGVTHFVEFGGKVLSPMVKRSASGEVETVSLI
CHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHCHHHHHHHHHHCCCCCEEEEEEE
SMDDIEALLKTL
CHHHHHHHHHHC
>Mature Secondary Structure
MRAFIFPGQGSQSVGMGRALADASSHAREVFQEVDDALGQKLFRLMSEGPEDQLTLTENA
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAIMANAIATLRVLEKEGGVTLAAKADYVAGHSLGEYSALCAAGAFDLATAARLLKTRG
CCHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHC
QAMQAAVPVGVGAMAALLGADIETAQRLADAAAEGEICTVANDNDPLQVVISGHKGAVER
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCHHHHH
AVALVKDYGIKRGVLLPVSAPFHCPLMQPAADAMAEALGANPPAAPLVPVVANVTASPVS
HHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCC
DADTIRDLLVQQVTGRVRWRESVGAMEDVGVTHFVEFGGKVLSPMVKRSASGEVETVSLI
CHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHCHHHHHHHHHHCCCCCEEEEEEE
SMDDIEALLKTL
CHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]