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The map label for this gene is cycW [H]

Identifier: 103487305

GI number: 103487305

Start: 1919906

End: 1920553

Strand: Reverse

Name: cycW [H]

Synonym: Sala_1821

Alternate gene names: 103487305

Gene position: 1920553-1919906 (Counterclockwise)

Preceding gene: 103487306

Following gene: 103487303

Centisome position: 57.41

GC content: 72.38

Gene sequence:

>648_bases
ATGACCGCACTTATCGCCCTCTTCTGGCGCGACCTGCGCCGCGCGTGGGGCAGCGGGGCGCTGTGGCTGCCGGTGCTCTT
CTTCCTGCTCGTCGCGACCGCCTTTCCCTTTGCGGTTGGCCCCGACGCGCCGCTGCTGCGCCGTGCGGGCGGCGGAATGG
TCTGGGTGGCCGCGCTGCTCGCCGCGCTGCTGCCGATCGACCGGCTGGTGCGGCCCGACCGCGACGCGGGCGTGCTTGAT
CAGCTCGCGGTCCGCGGCTTCGCCGATGAGCTGGTCGCAGCCGTGAAGATTGTCGCGCACGCGATCGCCTTTGGCATACC
GCTGCTCGTCGCGCTCCTGCCCGCCTCCGCCCTGCTCGCGCAGGACGCCGCGCGCGTCGAAACGCTTGCGATGGGGATTG
CCCTCGCGGTTCCGGCGCTCGCGTCGCTTGCGGTGCTGAGCGCCGCGCTGACCGCCGGTCACAAGGGCGGGAGCGCGGTC
GGCGGGCTGCTCATACTCCCGCTCGCGGTGCCGCTGCTGATCTTTGGCGCCGGGATGCTCGACCCGTCGGGACGCGGCGC
GATCAAGCTGCTTGCGGCGACGAGCCTGCTGCTGACGGTGATCGGTCCGTTTGCGGCGGGTGCGGCGCTGCGAGGACTGC
GCGAATGA

Upstream 100 bases:

>100_bases
CGTCAGCGCAGCGACGCAATCTCCAGCCCGAAGCATTGCGCGGCATCGATGGCCGGAGATTGCCGCGTCGCCACGCTCCT
CGTCGTGACCGGGATCGCGC

Downstream 100 bases:

>100_bases
CGGTTTTCCGCCGGAAGCGGACGTTTGGGGATCGGCAATCTCCCCTTCAGGCGCGCGATACGCGGCTTGCCGGCCTGTCC
GGCCAGCCGCAGTCGAGAAG

Product: cytochrome c-type biogenesis protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTALIALFWRDLRRAWGSGALWLPVLFFLLVATAFPFAVGPDAPLLRRAGGGMVWVAALLAALLPIDRLVRPDRDAGVLD
QLAVRGFADELVAAVKIVAHAIAFGIPLLVALLPASALLAQDAARVETLAMGIALAVPALASLAVLSAALTAGHKGGSAV
GGLLILPLAVPLLIFGAGMLDPSGRGAIKLLAATSLLLTVIGPFAAGAALRGLRE

Sequences:

>Translated_215_residues
MTALIALFWRDLRRAWGSGALWLPVLFFLLVATAFPFAVGPDAPLLRRAGGGMVWVAALLAALLPIDRLVRPDRDAGVLD
QLAVRGFADELVAAVKIVAHAIAFGIPLLVALLPASALLAQDAARVETLAMGIALAVPALASLAVLSAALTAGHKGGSAV
GGLLILPLAVPLLIFGAGMLDPSGRGAIKLLAATSLLLTVIGPFAAGAALRGLRE
>Mature_214_residues
TALIALFWRDLRRAWGSGALWLPVLFFLLVATAFPFAVGPDAPLLRRAGGGMVWVAALLAALLPIDRLVRPDRDAGVLDQ
LAVRGFADELVAAVKIVAHAIAFGIPLLVALLPASALLAQDAARVETLAMGIALAVPALASLAVLSAALTAGHKGGSAVG
GLLILPLAVPLLIFGAGMLDPSGRGAIKLLAATSLLLTVIGPFAAGAALRGLRE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=215, Percent_Identity=36.7441860465116, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 21880; Mature: 21748

Theoretical pI: Translated: 11.28; Mature: 11.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALIALFWRDLRRAWGSGALWLPVLFFLLVATAFPFAVGPDAPLLRRAGGGMVWVAALL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHH
AALLPIDRLVRPDRDAGVLDQLAVRGFADELVAAVKIVAHAIAFGIPLLVALLPASALLA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAARVETLAMGIALAVPALASLAVLSAALTAGHKGGSAVGGLLILPLAVPLLIFGAGML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DPSGRGAIKLLAATSLLLTVIGPFAAGAALRGLRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TALIALFWRDLRRAWGSGALWLPVLFFLLVATAFPFAVGPDAPLLRRAGGGMVWVAALL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHH
AALLPIDRLVRPDRDAGVLDQLAVRGFADELVAAVKIVAHAIAFGIPLLVALLPASALLA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAARVETLAMGIALAVPALASLAVLSAALTAGHKGGSAVGGLLILPLAVPLLIFGAGML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DPSGRGAIKLLAATSLLLTVIGPFAAGAALRGLRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]