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The map label for this gene is mutT [H]

Identifier: 103487276

GI number: 103487276

Start: 1889313

End: 1889741

Strand: Reverse

Name: mutT [H]

Synonym: Sala_1792

Alternate gene names: 103487276

Gene position: 1889741-1889313 (Counterclockwise)

Preceding gene: 103487279

Following gene: 103487274

Centisome position: 56.49

GC content: 64.57

Gene sequence:

>429_bases
TTGGCCGCGCTTGACCCCGTAAAACCGCCAAAAACCTCGCTTGTCGTCGCTGCGGCGGCGCTCGTCGACCGCGACGGCAG
GCTATTGGTGCAACAGCGGCCCGAGGGGCTTGCAATGGCGGGGTTATGGGAGTTTCCGGGCGGCAAGCTCGAACCCGGCG
AGACACCCGAGATGGCGCTCATCCGTGAACTCGATGAGGAGCTGGGGATCGCCGTCGATCAGGCGTGCCTTGCGCCCGCC
TGTTTCGCGAGCGACATGCTCGGCGACCGGCACCTTCTCCTTCTTCTTTATGTCTGTCGCAAATGGCGCGGTACGCCGAT
CGCGCGCCATGCAAGCGCGCTAGACTGGGTGCGTCCGGTCGAGCTTCACGCGCTTCCGATGCCGCCCGCCGACAAGCCGT
TGATCGGATTGCTGGAAGCGTTGATCTAG

Upstream 100 bases:

>100_bases
CTGGTCGACCGCATCAGCCTGTAAAGATTGCGCATTGCTCCACCCCTGACTGAAATATAGTTCCCGAGGCTGCCGACATT
TGCACAGGAAGGTTAACAAT

Downstream 100 bases:

>100_bases
CTAGGGTTTCGGCTTCAGCGCCGCTGCCAGCGAGGCCGTGCCGCTGCCGCGCCGCGCGGGCTGCGGCTGGTTGGGGTGCG
GCGCCCAGCCGCTGAAATAA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAALDPVKPPKTSLVVAAAALVDRDGRLLVQQRPEGLAMAGLWEFPGGKLEPGETPEMALIRELDEELGIAVDQACLAPA
CFASDMLGDRHLLLLLYVCRKWRGTPIARHASALDWVRPVELHALPMPPADKPLIGLLEALI

Sequences:

>Translated_142_residues
MAALDPVKPPKTSLVVAAAALVDRDGRLLVQQRPEGLAMAGLWEFPGGKLEPGETPEMALIRELDEELGIAVDQACLAPA
CFASDMLGDRHLLLLLYVCRKWRGTPIARHASALDWVRPVELHALPMPPADKPLIGLLEALI
>Mature_141_residues
AALDPVKPPKTSLVVAAAALVDRDGRLLVQQRPEGLAMAGLWEFPGGKLEPGETPEMALIRELDEELGIAVDQACLAPAC
FASDMLGDRHLLLLLYVCRKWRGTPIARHASALDWVRPVELHALPMPPADKPLIGLLEALI

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus lea

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786288, Length=129, Percent_Identity=34.1085271317829, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI1788056, Length=129, Percent_Identity=39.5348837209302, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003561
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15372; Mature: 15241

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALDPVKPPKTSLVVAAAALVDRDGRLLVQQRPEGLAMAGLWEFPGGKLEPGETPEMAL
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHH
IRELDEELGIAVDQACLAPACFASDMLGDRHLLLLLYVCRKWRGTPIARHASALDWVRPV
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
ELHALPMPPADKPLIGLLEALI
EEEECCCCCCCCHHHHHHHHHC
>Mature Secondary Structure 
AALDPVKPPKTSLVVAAAALVDRDGRLLVQQRPEGLAMAGLWEFPGGKLEPGETPEMAL
CCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHH
IRELDEELGIAVDQACLAPACFASDMLGDRHLLLLLYVCRKWRGTPIARHASALDWVRPV
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
ELHALPMPPADKPLIGLLEALI
EEEECCCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3033442; 1630901; 9278503; 2841285; 8202364; 3288626; 1851162; 1309939; 7578113; 9063868 [H]