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The map label for this gene is speB [H]

Identifier: 103487208

GI number: 103487208

Start: 1813120

End: 1813935

Strand: Reverse

Name: speB [H]

Synonym: Sala_1723

Alternate gene names: 103487208

Gene position: 1813935-1813120 (Counterclockwise)

Preceding gene: 103487209

Following gene: 103487207

Centisome position: 54.23

GC content: 68.87

Gene sequence:

>816_bases
ATGCCCGCGATCCGCCTGTTCGGCTTGCCGACCGACATCAACAGCAGTTTCGAGCGCGGCGCCGCGGGTGGTCCGGCGGC
GGTCCGTGCGGCGCTGTGGAGCGACCGCGGCAATATGGCGAGCGAGCTCGGCGGCGAAATTGGCGCTGACATCGCCTTTA
CCGACGATGGCGACCTGCCGCTCACCGAGAACAGCGCGCACGACGATGCCGCGATCCGCCGTCACGTCGCGATGCTGTGC
GAGGATGGCGAGGTGCCATTGGCGCTCGGCGGCGATCATGCGGTGACCTTTCCGCTCGTCGAGGCCGCGGCGACCTGTTT
TGGGCCGGTGAACATCCTCCATTTCGATGCTCACCCCGATCTCTATGACGATTTCGCCGGCAACCCGCGCAGCCATGCCT
CGCCCTTTGCGCGCATCTGCGAGGGCGGTCACGCCAAGCGGCTGGTGCAGGCGGGTATCCGCACGCTCAACCACCATTGC
CGCGAGCAGGCGGCGCGCTTCGGGGTCGAGATTGTCCCCATGGCGGGCTTCGCGCCCGACAAGGTGCCCGTGCTCGAAGG
ACCGCTGTATATCTCGATCGACCTCGACGGGATCGATCCGTCCGAAGCGCCGGGCGTCGCGCACCCCGAACCCGGCGGGC
TGACGGTGCGCGAAGTCCTCGCGGTGCTGCACAGGCAGACCGCGCCGATCGTCGGCGCCGACATCGTCGAGCATCACCCC
GGCCGCGACATCGGCGGCGTCACCGCGATCCTCGGCGCCAAGCTGGTGCGCGAACTCGCCGCGCTGATCGACCGCAACGG
GCCTTACCGCCCTTGA

Upstream 100 bases:

>100_bases
GTCATCGCGCTCTAATGGGTCCTGACCCTAGCGGTCGCATGGAATCCCCGTGCAACGGAGCGCGCCTTGCGCGCCCGCTG
GCAATGGCTACAGATGATCC

Downstream 100 bases:

>100_bases
ATCCCCCGCCCGCAAAGGAGAACCCATGACCCTGATCGTCCACCACCTCAACAACAGCCGGTCGCAGCGCATCTTGTGGC
TGCTCGAGGAAATCGGCGCG

Product: arginase/agmatinase/formiminoglutamase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MPAIRLFGLPTDINSSFERGAAGGPAAVRAALWSDRGNMASELGGEIGADIAFTDDGDLPLTENSAHDDAAIRRHVAMLC
EDGEVPLALGGDHAVTFPLVEAAATCFGPVNILHFDAHPDLYDDFAGNPRSHASPFARICEGGHAKRLVQAGIRTLNHHC
REQAARFGVEIVPMAGFAPDKVPVLEGPLYISIDLDGIDPSEAPGVAHPEPGGLTVREVLAVLHRQTAPIVGADIVEHHP
GRDIGGVTAILGAKLVRELAALIDRNGPYRP

Sequences:

>Translated_271_residues
MPAIRLFGLPTDINSSFERGAAGGPAAVRAALWSDRGNMASELGGEIGADIAFTDDGDLPLTENSAHDDAAIRRHVAMLC
EDGEVPLALGGDHAVTFPLVEAAATCFGPVNILHFDAHPDLYDDFAGNPRSHASPFARICEGGHAKRLVQAGIRTLNHHC
REQAARFGVEIVPMAGFAPDKVPVLEGPLYISIDLDGIDPSEAPGVAHPEPGGLTVREVLAVLHRQTAPIVGADIVEHHP
GRDIGGVTAILGAKLVRELAALIDRNGPYRP
>Mature_270_residues
PAIRLFGLPTDINSSFERGAAGGPAAVRAALWSDRGNMASELGGEIGADIAFTDDGDLPLTENSAHDDAAIRRHVAMLCE
DGEVPLALGGDHAVTFPLVEAAATCFGPVNILHFDAHPDLYDDFAGNPRSHASPFARICEGGHAKRLVQAGIRTLNHHCR
EQAARFGVEIVPMAGFAPDKVPVLEGPLYISIDLDGIDPSEAPGVAHPEPGGLTVREVLAVLHRQTAPIVGADIVEHHPG
RDIGGVTAILGAKLVRELAALIDRNGPYRP

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=275, Percent_Identity=32.7272727272727, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1789306, Length=250, Percent_Identity=32, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 28514; Mature: 28382

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAIRLFGLPTDINSSFERGAAGGPAAVRAALWSDRGNMASELGGEIGADIAFTDDGDLP
CCCEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHCHHHCCCEEEECCCCCC
LTENSAHDDAAIRRHVAMLCEDGEVPLALGGDHAVTFPLVEAAATCFGPVNILHFDAHPD
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHCCCCEEEEECCCCC
LYDDFAGNPRSHASPFARICEGGHAKRLVQAGIRTLNHHCREQAARFGVEIVPMAGFAPD
HHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
KVPVLEGPLYISIDLDGIDPSEAPGVAHPEPGGLTVREVLAVLHRQTAPIVGADIVEHHP
CCCEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCC
GRDIGGVTAILGAKLVRELAALIDRNGPYRP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PAIRLFGLPTDINSSFERGAAGGPAAVRAALWSDRGNMASELGGEIGADIAFTDDGDLP
CCEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHCHHHCCCEEEECCCCCC
LTENSAHDDAAIRRHVAMLCEDGEVPLALGGDHAVTFPLVEAAATCFGPVNILHFDAHPD
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHCCCCEEEEECCCCC
LYDDFAGNPRSHASPFARICEGGHAKRLVQAGIRTLNHHCREQAARFGVEIVPMAGFAPD
HHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
KVPVLEGPLYISIDLDGIDPSEAPGVAHPEPGGLTVREVLAVLHRQTAPIVGADIVEHHP
CCCEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCC
GRDIGGVTAILGAKLVRELAALIDRNGPYRP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]