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The map label for this gene is hutC [H]

Identifier: 103487171

GI number: 103487171

Start: 1774937

End: 1775617

Strand: Reverse

Name: hutC [H]

Synonym: Sala_1686

Alternate gene names: 103487171

Gene position: 1775617-1774937 (Counterclockwise)

Preceding gene: 103487172

Following gene: 103487170

Centisome position: 53.08

GC content: 71.37

Gene sequence:

>681_bases
ATGAACCCCGCGCGGCGCATCCGCGATGAAATCGCCGCCGCGATCCGCGCGGGCGAATGGCGCCCCGGCGACCGTGTGCC
GATCGAGCAGGACCTTGCCGCGCACTATGGCTGCGCGCGCGCGACGGTGAGCAAGGCGCTTGGCGAGCTCGCCGCCGCCG
GGCTGATTGAGCGCCGTCGCAAGGCGGGGACGTTCGTCGCGCATCCGCCGGTCCATTCGGCGGTGATGACGGTGCCCGAC
CTCGCCGAACTGATCGCCGCACGGGGCGAGGCCTATGGCTGGACGCTGAAAGCAACGCGCACCGAAGCGGAGGGCGCCGC
GCTGTGCCCCGCCCCCGCGCTATACGTCGAGGGCGTGCATTTTGCGGCGGGGGAGCCCTTCGCGCTCGAAGCGCGCTTCA
TCGCGCTCGGCGAAGTGCCCGACGCAGCGAGTGCCGATTTTCGGTCGGAGGCGCCTGGCACCTGGCTGCTTGGCCATATT
CCGTGGACCGAGGCGCGGCATGTGATCCGCGCGGTGACGCCGACGCGGGCGGAGGCGGCGCAATTGGGTGTCGGGACGTG
CGCCGCCTGTCTCGAACTCGACCGCACCACCTGGCGCGCGGGGCGGATTGTCACCCACGTCAGGCAGTTGTTCCGCGGCG
ACCGCTTCGACCTCGTCGCCCAATTCAACGCCGGGGCGTGA

Upstream 100 bases:

>100_bases
GCGTCTGGCGCGCGGGCGAAAAGCGCGTCGAAAGCGGGCGCCATGTCGCGGCGGACGCTGTCGCCGCCGCCTATCGCGCC
TGCCTCGACCGGCTGCTTGC

Downstream 100 bases:

>100_bases
CCGGGTTGCGATGCGGGCGAGGCGCCGGGCAGGGGCAAGGACCGATTAACCATGTCCGGAAACCCGGAAGCAATCTTTAT
TACCGATTGTTAGCAAAACA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MNPARRIRDEIAAAIRAGEWRPGDRVPIEQDLAAHYGCARATVSKALGELAAAGLIERRRKAGTFVAHPPVHSAVMTVPD
LAELIAARGEAYGWTLKATRTEAEGAALCPAPALYVEGVHFAAGEPFALEARFIALGEVPDAASADFRSEAPGTWLLGHI
PWTEARHVIRAVTPTRAEAAQLGVGTCAACLELDRTTWRAGRIVTHVRQLFRGDRFDLVAQFNAGA

Sequences:

>Translated_226_residues
MNPARRIRDEIAAAIRAGEWRPGDRVPIEQDLAAHYGCARATVSKALGELAAAGLIERRRKAGTFVAHPPVHSAVMTVPD
LAELIAARGEAYGWTLKATRTEAEGAALCPAPALYVEGVHFAAGEPFALEARFIALGEVPDAASADFRSEAPGTWLLGHI
PWTEARHVIRAVTPTRAEAAQLGVGTCAACLELDRTTWRAGRIVTHVRQLFRGDRFDLVAQFNAGA
>Mature_226_residues
MNPARRIRDEIAAAIRAGEWRPGDRVPIEQDLAAHYGCARATVSKALGELAAAGLIERRRKAGTFVAHPPVHSAVMTVPD
LAELIAARGEAYGWTLKATRTEAEGAALCPAPALYVEGVHFAAGEPFALEARFIALGEVPDAASADFRSEAPGTWLLGHI
PWTEARHVIRAVTPTRAEAAQLGVGTCAACLELDRTTWRAGRIVTHVRQLFRGDRFDLVAQFNAGA

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 24235; Mature: 24235

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPARRIRDEIAAAIRAGEWRPGDRVPIEQDLAAHYGCARATVSKALGELAAAGLIERRR
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAGTFVAHPPVHSAVMTVPDLAELIAARGEAYGWTLKATRTEAEGAALCPAPALYVEGVH
HCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCEE
FAAGEPFALEARFIALGEVPDAASADFRSEAPGTWLLGHIPWTEARHVIRAVTPTRAEAA
ECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHH
QLGVGTCAACLELDRTTWRAGRIVTHVRQLFRGDRFDLVAQFNAGA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
>Mature Secondary Structure
MNPARRIRDEIAAAIRAGEWRPGDRVPIEQDLAAHYGCARATVSKALGELAAAGLIERRR
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAGTFVAHPPVHSAVMTVPDLAELIAARGEAYGWTLKATRTEAEGAALCPAPALYVEGVH
HCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHCCEE
FAAGEPFALEARFIALGEVPDAASADFRSEAPGTWLLGHIPWTEARHVIRAVTPTRAEAA
ECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCHHHHH
QLGVGTCAACLELDRTTWRAGRIVTHVRQLFRGDRFDLVAQFNAGA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2203754; 2834335 [H]