BacMap

Definition	Sphingopyxis alaskensis RB2256, complete genome.
Accession	NC_008048
Length	3,345,170

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The map label for this gene is fabG [H]

Identifier: 103487062

GI number: 103487062

Start: 1649923

End: 1650720

Strand: Reverse

Name: fabG [H]

Synonym: Sala_1577

Alternate gene names: 103487062

Gene position: 1650720-1649923 (Counterclockwise)

Preceding gene: 103487063

Following gene: 103487061

Centisome position: 49.35

GC content: 61.65

Gene sequence:

>798_bases
ATGAGCAAGGATCGTCCGCTTTCAGGAAAGCTGGTGGTGCTCACCGGCGCGGGCGGCATCATCGGACGTGTCGCGACCGG
CCTGTTCGTTCGCAACGGTGCGCGTCTGGTGATGGTCGACCGGTGCGAACAGGCCCTGACTGCGGCGCGGGAAGCGCTGG
GGGATGACAAGGCAGCGGCGTTCGCCATGCCCTGCGACCTGACCGACCCGCGGCAGGTCGCGGAACTGGCCGAAAACGTC
GGTGCGGAGCACGGGCCGGTCGATGCCCTGTTCAACAACGTAGCCGGCAAGACGCAGAATATCTTTGCGCCATTCGAACA
TTTTCCGCTGGACGAATGGAATGAGGTAATGGCGATGAACCTGACCACGGCGATGCTGTGCTGCCAGCATTTCGGCGCGC
AAATGGCGGCGCGGGGGCAGGGAACAATCGTCAATACGCTTTCCATCTATGGCATCGTCGGGCCGGATCAGCGCATTTAC
GACGGCGCCCAATATGAAGGCCGCGCCATCAACTCACCAGCGGTTTACAGCGCGGCAAAGGCGGGGCTGTGGGGACTGAC
GAAATATCTTGCCACCTACTGGGGTCCAAAGGGCGTGCGCGTCAATGCCGTGACGCCAGGCGGCGTTTACAGCGGCCAGA
ACGAAACCTTTGTTGACCGATATTCTGCCCGTGTGCCGATGGGACGCATGGCGAAAGCCGAAGAGATTGCGGACGCCATG
CTGTTTCTCGCCAGCGATGGCGCGTCCTACATCAATGGCCAGAACATCGTGGTTGACGGAGGGCTGACGACATGGTGA

Upstream 100 bases:

>100_bases
AACCGCGCCTGCACGTCATGCCGCGTGAAAGGTCCATCGACATCGATTCCGAACTGGATTTCAAACTGGTCGAACTGTTG
ATGCGCGAAAGGCTGGAGCA

Downstream 100 bases:

>100_bases
GCGGCGAGCGGTCCGTCGAACGGACATTCGTTATCGCGGAAGCGGGCGTCAACCACGACGGATCGCTCGACAAGGCGTTG
CGTCTTGTCGATATCGCCGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSKDRPLSGKLVVLTGAGGIIGRVATGLFVRNGARLVMVDRCEQALTAAREALGDDKAAAFAMPCDLTDPRQVAELAENV
GAEHGPVDALFNNVAGKTQNIFAPFEHFPLDEWNEVMAMNLTTAMLCCQHFGAQMAARGQGTIVNTLSIYGIVGPDQRIY
DGAQYEGRAINSPAVYSAAKAGLWGLTKYLATYWGPKGVRVNAVTPGGVYSGQNETFVDRYSARVPMGRMAKAEEIADAM
LFLASDGASYINGQNIVVDGGLTTW

Sequences:

>Translated_265_residues
MSKDRPLSGKLVVLTGAGGIIGRVATGLFVRNGARLVMVDRCEQALTAAREALGDDKAAAFAMPCDLTDPRQVAELAENV
GAEHGPVDALFNNVAGKTQNIFAPFEHFPLDEWNEVMAMNLTTAMLCCQHFGAQMAARGQGTIVNTLSIYGIVGPDQRIY
DGAQYEGRAINSPAVYSAAKAGLWGLTKYLATYWGPKGVRVNAVTPGGVYSGQNETFVDRYSARVPMGRMAKAEEIADAM
LFLASDGASYINGQNIVVDGGLTTW
>Mature_264_residues
SKDRPLSGKLVVLTGAGGIIGRVATGLFVRNGARLVMVDRCEQALTAAREALGDDKAAAFAMPCDLTDPRQVAELAENVG
AEHGPVDALFNNVAGKTQNIFAPFEHFPLDEWNEVMAMNLTTAMLCCQHFGAQMAARGQGTIVNTLSIYGIVGPDQRIYD
GAQYEGRAINSPAVYSAAKAGLWGLTKYLATYWGPKGVRVNAVTPGGVYSGQNETFVDRYSARVPMGRMAKAEEIADAML
FLASDGASYINGQNIVVDGGLTTW

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=27.2388059701493, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI15277342, Length=271, Percent_Identity=30.2583025830258, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=31.8181818181818, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=30.4526748971193, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI10190704, Length=264, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI66933014, Length=271, Percent_Identity=30.2583025830258, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4503301, Length=238, Percent_Identity=28.9915966386555, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=271, Percent_Identity=25.0922509225092, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI5031737, Length=267, Percent_Identity=25.8426966292135, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI59889578, Length=243, Percent_Identity=27.1604938271605, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723750, Length=268, Percent_Identity=20.8955223880597, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=31.5384615384615, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=27.7566539923954, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI2367175, Length=264, Percent_Identity=32.1969696969697, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788459, Length=183, Percent_Identity=32.2404371584699, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082100, Length=269, Percent_Identity=28.996282527881, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787905, Length=265, Percent_Identity=26.7924528301887, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=275, Percent_Identity=29.4545454545455, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789208, Length=266, Percent_Identity=29.3233082706767, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=278, Percent_Identity=27.3381294964029, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=25.0950570342205, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=23.9543726235741, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=267, Percent_Identity=33.7078651685393, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25147288, Length=264, Percent_Identity=30.6818181818182, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=28.8321167883212, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=278, Percent_Identity=28.7769784172662, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=276, Percent_Identity=28.6231884057971, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=278, Percent_Identity=28.7769784172662, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=27.4021352313167, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=275, Percent_Identity=26.9090909090909, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=278, Percent_Identity=26.6187050359712, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=28.6259541984733, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=270, Percent_Identity=26.2962962962963, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=274, Percent_Identity=28.4671532846715, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=274, Percent_Identity=26.6423357664234, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=278, Percent_Identity=27.3381294964029, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=26.4492753623188, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=28, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=270, Percent_Identity=25.1851851851852, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=210, Percent_Identity=28.0952380952381, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=265, Percent_Identity=26.7924528301887, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=157, Percent_Identity=26.1146496815287, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=275, Percent_Identity=26.5454545454545, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=30.1526717557252, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=26.4150943396226, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28571526, Length=266, Percent_Identity=30.8270676691729, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=28.1368821292776, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI23397609, Length=267, Percent_Identity=30.7116104868914, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24643142, Length=265, Percent_Identity=27.9245283018868, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644337, Length=266, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24644339, Length=266, Percent_Identity=27.0676691729323, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28228; Mature: 28097

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDRPLSGKLVVLTGAGGIIGRVATGLFVRNGARLVMVDRCEQALTAAREALGDDKAAA
CCCCCCCCCEEEEEECCCHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHCCCCCEE
FAMPCDLTDPRQVAELAENVGAEHGPVDALFNNVAGKTQNIFAPFEHFPLDEWNEVMAMN
EEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHH
LTTAMLCCQHFGAQMAARGQGTIVNTLSIYGIVGPDQRIYDGAQYEGRAINSPAVYSAAK
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCHHCCCCCCCCEECCCCHHHHHHH
AGLWGLTKYLATYWGPKGVRVNAVTPGGVYSGQNETFVDRYSARVPMGRMAKAEEIADAM
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LFLASDGASYINGQNIVVDGGLTTW
HHHCCCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SKDRPLSGKLVVLTGAGGIIGRVATGLFVRNGARLVMVDRCEQALTAAREALGDDKAAA
CCCCCCCCEEEEEECCCHHHHHHHHHHEEECCCEEEEHHHHHHHHHHHHHHHCCCCCEE
FAMPCDLTDPRQVAELAENVGAEHGPVDALFNNVAGKTQNIFAPFEHFPLDEWNEVMAMN
EEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHH
LTTAMLCCQHFGAQMAARGQGTIVNTLSIYGIVGPDQRIYDGAQYEGRAINSPAVYSAAK
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCHHCCCCCCCCEECCCCHHHHHHH
AGLWGLTKYLATYWGPKGVRVNAVTPGGVYSGQNETFVDRYSARVPMGRMAKAEEIADAM
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
LFLASDGASYINGQNIVVDGGLTTW
HHHCCCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]