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The map label for this gene is ldh [H]

Identifier: 103487006

GI number: 103487006

Start: 1586256

End: 1587305

Strand: Reverse

Name: ldh [H]

Synonym: Sala_1521

Alternate gene names: 103487006

Gene position: 1587305-1586256 (Counterclockwise)

Preceding gene: 103487008

Following gene: 103487005

Centisome position: 47.45

GC content: 67.05

Gene sequence:

>1050_bases
ATGTCCGCTGTCTGGGATTTCGCCGATTTCGACGATCACGAACATGTCCACATGTTCCGCGATCGCGCCAGCGGGCTGAC
CGCGGTTATCGCCGTCCACTCGACATACCTTGGCCCCGGCGCGGGCGGCGTGCGATACTGGCATTATCCGCAGCGCGCCG
CCGCAATCACCGACGCGCTGCGCCTGTCGCGCGGGATGAGCTATAAAAATGCGATGGCGGGGCTGCCGATGGGCGGCGGC
AAGGGCGTGATCCTGGCCGACGAAGGACAGGAAAAGAGACCCGAACTGCTCGCCGCATTCGGGCGCGCTGTCGATTCGCT
CGGCGGCGCCTATGTGACCGCCGAGGATGTCGGCATCACCGACGCCGACATGGTCGAGATTTCCAGGCAGACGAAGCATG
TCAGCGGGCTGCCCGTGGCGAGCGGCGAGGCCGGGGGCGATCCGGGGCCGTTCACCGCGCTCGGCGTCTACCTCGGCATC
AAGGCGGCGATTCGCGAAGGGTTGGGCACCGACAGCGCGAAAGATGTGCGCGTCGCGATCCAGGGTGTCGGCAGCGTCGG
CGGTGGCGTCGCGCGGCGGCTCGCGGCCGAGGGCGCGAAGCTGACCCTCGCCGACGTCAACCTGGCGCGCGCGAAGGCGC
TCGCCGAGGAACTGGGCGCCGAACTCGCCGATTCGGCGGCGATCATGGAGATCGAGGCCGATGTGCTCAGCCCCAATGCG
CTGGGTGCGATTCTGACCGAACGGAGCATCGAGAAGTTGAAGGTGCCGATCGTCGCGGGCGGCGCAAACAATCAGCTCGC
AACCGCTCTCGACGGCCAGCGCATCCACGACCGCGGCATCGTCTATGCCCCCGACTATGTCATCAACGCCGGCGGGATCA
TCAATGTCGCGCTGGAGTATCTTGGACAGGGAAGCCAGGACGAGGTCGAAAGCCGTATCCGGCTGATCCCCGGCCGGCTC
GCCGAAATCTGGGCCGAGAGCAAGGCGAGCGGTACCCCCGCCTCGGTCGTCGCCGACCGTATGGCGCAAAAACTGATCGG
GCGCGGGTGA

Upstream 100 bases:

>100_bases
CCATTTTCGCTTGGGCCGCTGACAGGCGCTTTTGGGGTGACTCGCTGCCCCTGTTTGATTATTACATCTTCACGTAATTT
TTTAACGTGAGGAAGCTGCC

Downstream 100 bases:

>100_bases
TCCGGCAACGCGCGCCGTCATCCCGGCCAGGGCCGGAAGCGCGACCTTGCATCAAGCAATTATGGCGCGATCCCGGCTGT
CACCCGGCTGGCGGAATGCG

Product: Glu/Leu/Phe/Val dehydrogenase, dimerisation region

Products: NA

Alternate protein names: LeuDH [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSAVWDFADFDDHEHVHMFRDRASGLTAVIAVHSTYLGPGAGGVRYWHYPQRAAAITDALRLSRGMSYKNAMAGLPMGGG
KGVILADEGQEKRPELLAAFGRAVDSLGGAYVTAEDVGITDADMVEISRQTKHVSGLPVASGEAGGDPGPFTALGVYLGI
KAAIREGLGTDSAKDVRVAIQGVGSVGGGVARRLAAEGAKLTLADVNLARAKALAEELGAELADSAAIMEIEADVLSPNA
LGAILTERSIEKLKVPIVAGGANNQLATALDGQRIHDRGIVYAPDYVINAGGIINVALEYLGQGSQDEVESRIRLIPGRL
AEIWAESKASGTPASVVADRMAQKLIGRG

Sequences:

>Translated_349_residues
MSAVWDFADFDDHEHVHMFRDRASGLTAVIAVHSTYLGPGAGGVRYWHYPQRAAAITDALRLSRGMSYKNAMAGLPMGGG
KGVILADEGQEKRPELLAAFGRAVDSLGGAYVTAEDVGITDADMVEISRQTKHVSGLPVASGEAGGDPGPFTALGVYLGI
KAAIREGLGTDSAKDVRVAIQGVGSVGGGVARRLAAEGAKLTLADVNLARAKALAEELGAELADSAAIMEIEADVLSPNA
LGAILTERSIEKLKVPIVAGGANNQLATALDGQRIHDRGIVYAPDYVINAGGIINVALEYLGQGSQDEVESRIRLIPGRL
AEIWAESKASGTPASVVADRMAQKLIGRG
>Mature_348_residues
SAVWDFADFDDHEHVHMFRDRASGLTAVIAVHSTYLGPGAGGVRYWHYPQRAAAITDALRLSRGMSYKNAMAGLPMGGGK
GVILADEGQEKRPELLAAFGRAVDSLGGAYVTAEDVGITDADMVEISRQTKHVSGLPVASGEAGGDPGPFTALGVYLGIK
AAIREGLGTDSAKDVRVAIQGVGSVGGGVARRLAAEGAKLTLADVNLARAKALAEELGAELADSAAIMEIEADVLSPNAL
GAILTERSIEKLKVPIVAGGANNQLATALDGQRIHDRGIVYAPDYVINAGGIINVALEYLGQGSQDEVESRIRLIPGRLA
EIWAESKASGTPASVVADRMAQKLIGRG

Specific function: Functions catabolically in the bacterial metabolism of branched-chain L-amino acids. Catalyzes the reversible deamination of these branched-chain L-amino acids to their oxo analogs [H]

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.9 [H]

Molecular weight: Translated: 36244; Mature: 36112

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVWDFADFDDHEHVHMFRDRASGLTAVIAVHSTYLGPGAGGVRYWHYPQRAAAITDAL
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCEEEECCHHHHHHHHHH
RLSRGMSYKNAMAGLPMGGGKGVILADEGQEKRPELLAAFGRAVDSLGGAYVTAEDVGIT
HHHHCCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCC
DADMVEISRQTKHVSGLPVASGEAGGDPGPFTALGVYLGIKAAIREGLGTDSAKDVRVAI
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
QGVGSVGGGVARRLAAEGAKLTLADVNLARAKALAEELGAELADSAAIMEIEADVLSPNA
EECCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCH
LGAILTERSIEKLKVPIVAGGANNQLATALDGQRIHDRGIVYAPDYVINAGGIINVALEY
HHHHHHHHHHHHEEEEEEECCCCCCEEECCCCCEECCCCCEECCCEEECCCCHHHHHHHH
LGQGSQDEVESRIRLIPGRLAEIWAESKASGTPASVVADRMAQKLIGRG
HCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAVWDFADFDDHEHVHMFRDRASGLTAVIAVHSTYLGPGAGGVRYWHYPQRAAAITDAL
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCEEEECCHHHHHHHHHH
RLSRGMSYKNAMAGLPMGGGKGVILADEGQEKRPELLAAFGRAVDSLGGAYVTAEDVGIT
HHHHCCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCC
DADMVEISRQTKHVSGLPVASGEAGGDPGPFTALGVYLGIKAAIREGLGTDSAKDVRVAI
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
QGVGSVGGGVARRLAAEGAKLTLADVNLARAKALAEELGAELADSAAIMEIEADVLSPNA
EECCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCH
LGAILTERSIEKLKVPIVAGGANNQLATALDGQRIHDRGIVYAPDYVINAGGIINVALEY
HHHHHHHHHHHHEEEEEEECCCCCCEEECCCCCEECCCCCEECCCEEECCCCHHHHHHHH
LGQGSQDEVESRIRLIPGRLAEIWAESKASGTPASVVADRMAQKLIGRG
HCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020469 [H]