Click here to switch to the map view.

The map label for this gene is cyoB [H]

Identifier: 103486992

GI number: 103486992

Start: 1568940

End: 1570958

Strand: Reverse

Name: cyoB [H]

Synonym: Sala_1507

Alternate gene names: 103486992

Gene position: 1570958-1568940 (Counterclockwise)

Preceding gene: 103486993

Following gene: 103486991

Centisome position: 46.96

GC content: 61.81

Gene sequence:

>2019_bases
ATGTCCGACGCCATCATCCCGCATCCCGCGCCCCCGACGCACCCGATCTTCGGCAAGCTGTCGGTCGACGCGATCCCGCT
GCACGAGCCGATCCTGGTCGCGACCTTCATCGGCGTGGCGATCGGCGGTATCGCCGTGCTCGCGCTGCTCACCAGATATC
GCCTGTGGGGCTATTTGTGGAAGGAGTGGTTCACCACGGTCGACCACAAGCGCATCGGGATCATGTACATGATCCTGGGG
CTGATCATGTTCCTGCGCGGTTTTGCCGACGCGATCATGATGCGATTGCAGCAGGTGATGGCGTTCGGCGGGTCCGAGGG
CTATCTCAACGCGCATCATTATGACCAGGTGTTCACCGCGCACGGCGTCATCATGATCTTTTTCGTCGCAATGCCGTTCA
TCACCGGCCTGATGAACTATATCGTGCCGCTCCAGATCGGCGCGCGCGACGTCAGCTTTCCCTTCCTCAACAATTTCAGC
TTCTGGATGACGAGCGCGGGCGCGGCGCTGACGATGATCTCGCTGTTCGTCGGCGAATATGCGCAGACCGGCTGGCTGGC
CTATCCGCCCTTGTCGGGCATCGCCTACAGCCCCAATGTCGGGGTCGATTATTATATCTGGGGGCTTCAGATCGCCGGGG
TTGGCACCACGCTGTCGGGCATCAACCTGATCGTCACCATCCTGAAGCTGCGCGCGCCGGGCATGGGGCTGATGAAGATG
CCGGTCTTTACCTGGACGTCGCTCTGCTCGAACATATTGATCGTCGCGAGTTTCCCGATCCTGACCGCGACGCTCGCGCT
GCTCAGCCTCGATCGCTACGCGGGGACCAATTTCTTCACCAACGATCTCGGCGGATCGCCGATGATGTATGTGAACCTGA
TCTGGATCTGGGGGCACCCGGAGGTCTACATCCTCATCCTGCCGCTGTTCGGCGTCTTTTCCGAAGTCACCTCGACCTTC
TCGGGTAAAAGGCTCTTCGGCTATACGTCGATGGTTTATGCGACGGTGTGCATCACGATCCTGTCGTACATCGTCTGGCT
GCACCATTTCTTCACCATGGGGTCGGGCGCCAGCGTCAACAGCTTTTTCGGCATCACGACGATGGTGATTTCGATCCCGA
CGGGAGCCAAGCTCTTCAACTGGCTCTTCACCATGTACCGCGGCCGCATTCGCTATGAACTGCCGATGATGTGGACGATC
GCCTTCATGCTGACCTTCGTCGTCGGCGGCATGACCGGGGTGTTGCTCGCGGTGCCGCCCGCCGACTTTGTGCTGCACAA
TTCGCTGTTTCTGATCGCGCATTTCCACAATGTCATCATCGGCGGCGTGTTGTTCGGTCTGTTCGCGGCGATCAATTACT
GGTGGCCCAAGGCGTTCGGGTTCAAGCTCGATGTGTTCTGGGGCAAGGTCAGCTTCTGGTGCTGGGTCGTCGGTTTCTGG
GTCGCCTTTACCCCGCTCTATATCCTCGGCCTGATGGGCGTCACGCGGCGGATGCGCGTGTTCGATGACCCCAGCCTGCA
AATCTGGTTCGCGATCGCCGGGGTCGGCGCGCTGATCATCGCCGCGGGCATCGGCGCGATGCTCGTCCAGTTCGCGGTCA
GCATCTGGCGCCGCAAGGAGCTCGCCGAGGAAAGCGGCGATCCGTGGGACGGGCGCACGCTCGAATGGGCGACCAGCTCG
CCGCCGCCCGACTATAATTTCGCCTTCACGCCCGTCATTCACGACCTCGACGCCTGGTACGACATGAAGAAGCGCGGGGG
GCAGCGGCCGGTTGGCGGGTTCCGCGACATTCACATGCCGAGCAATACGGGCGCGGGGATCATCCTGTCGGGCCTCTGCC
TTGTCCTGGGGTTCGCGCTCGTCTGGCATATCTGGTGGCTGGTCGGGCTGAGCTTCGTCGCGGTGATCGCGGGGGCGATC
ATCCACACCTTCAACTACAAGCGCGATTTCGACATTCCGGCGGCGACCGTCGCGGCGATCGAGGGCGCGCGCACCCGCCA
GCTGGCGGCCGGAGCCTGA

Upstream 100 bases:

>100_bases
GGGCGAGGGGCTGCCGTTGCCGGGCAAGACCGCCCGCACCGCGCTGAACGCGCCCGCCGCTACGCGCCCGCTGTCCTGAC
CGTCTGCCGAGCTGAAACCC

Downstream 100 bases:

>100_bases
TGCGATGAGTGCTACGACCCTGACCGCCGACGAGCCTGTCCGCTTCTACGACCTCGACGAACATCCGCATCCCGAAGGGC
ACAGCACGATGCTGGGCTTC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSDAIIPHPAPPTHPIFGKLSVDAIPLHEPILVATFIGVAIGGIAVLALLTRYRLWGYLWKEWFTTVDHKRIGIMYMILG
LIMFLRGFADAIMMRLQQVMAFGGSEGYLNAHHYDQVFTAHGVIMIFFVAMPFITGLMNYIVPLQIGARDVSFPFLNNFS
FWMTSAGAALTMISLFVGEYAQTGWLAYPPLSGIAYSPNVGVDYYIWGLQIAGVGTTLSGINLIVTILKLRAPGMGLMKM
PVFTWTSLCSNILIVASFPILTATLALLSLDRYAGTNFFTNDLGGSPMMYVNLIWIWGHPEVYILILPLFGVFSEVTSTF
SGKRLFGYTSMVYATVCITILSYIVWLHHFFTMGSGASVNSFFGITTMVISIPTGAKLFNWLFTMYRGRIRYELPMMWTI
AFMLTFVVGGMTGVLLAVPPADFVLHNSLFLIAHFHNVIIGGVLFGLFAAINYWWPKAFGFKLDVFWGKVSFWCWVVGFW
VAFTPLYILGLMGVTRRMRVFDDPSLQIWFAIAGVGALIIAAGIGAMLVQFAVSIWRRKELAEESGDPWDGRTLEWATSS
PPPDYNFAFTPVIHDLDAWYDMKKRGGQRPVGGFRDIHMPSNTGAGIILSGLCLVLGFALVWHIWWLVGLSFVAVIAGAI
IHTFNYKRDFDIPAATVAAIEGARTRQLAAGA

Sequences:

>Translated_672_residues
MSDAIIPHPAPPTHPIFGKLSVDAIPLHEPILVATFIGVAIGGIAVLALLTRYRLWGYLWKEWFTTVDHKRIGIMYMILG
LIMFLRGFADAIMMRLQQVMAFGGSEGYLNAHHYDQVFTAHGVIMIFFVAMPFITGLMNYIVPLQIGARDVSFPFLNNFS
FWMTSAGAALTMISLFVGEYAQTGWLAYPPLSGIAYSPNVGVDYYIWGLQIAGVGTTLSGINLIVTILKLRAPGMGLMKM
PVFTWTSLCSNILIVASFPILTATLALLSLDRYAGTNFFTNDLGGSPMMYVNLIWIWGHPEVYILILPLFGVFSEVTSTF
SGKRLFGYTSMVYATVCITILSYIVWLHHFFTMGSGASVNSFFGITTMVISIPTGAKLFNWLFTMYRGRIRYELPMMWTI
AFMLTFVVGGMTGVLLAVPPADFVLHNSLFLIAHFHNVIIGGVLFGLFAAINYWWPKAFGFKLDVFWGKVSFWCWVVGFW
VAFTPLYILGLMGVTRRMRVFDDPSLQIWFAIAGVGALIIAAGIGAMLVQFAVSIWRRKELAEESGDPWDGRTLEWATSS
PPPDYNFAFTPVIHDLDAWYDMKKRGGQRPVGGFRDIHMPSNTGAGIILSGLCLVLGFALVWHIWWLVGLSFVAVIAGAI
IHTFNYKRDFDIPAATVAAIEGARTRQLAAGA
>Mature_671_residues
SDAIIPHPAPPTHPIFGKLSVDAIPLHEPILVATFIGVAIGGIAVLALLTRYRLWGYLWKEWFTTVDHKRIGIMYMILGL
IMFLRGFADAIMMRLQQVMAFGGSEGYLNAHHYDQVFTAHGVIMIFFVAMPFITGLMNYIVPLQIGARDVSFPFLNNFSF
WMTSAGAALTMISLFVGEYAQTGWLAYPPLSGIAYSPNVGVDYYIWGLQIAGVGTTLSGINLIVTILKLRAPGMGLMKMP
VFTWTSLCSNILIVASFPILTATLALLSLDRYAGTNFFTNDLGGSPMMYVNLIWIWGHPEVYILILPLFGVFSEVTSTFS
GKRLFGYTSMVYATVCITILSYIVWLHHFFTMGSGASVNSFFGITTMVISIPTGAKLFNWLFTMYRGRIRYELPMMWTIA
FMLTFVVGGMTGVLLAVPPADFVLHNSLFLIAHFHNVIIGGVLFGLFAAINYWWPKAFGFKLDVFWGKVSFWCWVVGFWV
AFTPLYILGLMGVTRRMRVFDDPSLQIWFAIAGVGALIIAAGIGAMLVQFAVSIWRRKELAEESGDPWDGRTLEWATSSP
PPDYNFAFTPVIHDLDAWYDMKKRGGQRPVGGFRDIHMPSNTGAGIILSGLCLVLGFALVWHIWWLVGLSFVAVIAGAII
HTFNYKRDFDIPAATVAAIEGARTRQLAAGA

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer [H]

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=514, Percent_Identity=37.15953307393, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1786634, Length=654, Percent_Identity=64.0672782874618, Blast_Score=885, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=35.5679702048417, Blast_Score=324, Evalue=2e-89,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=232, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6226523, Length=252, Percent_Identity=34.5238095238095, Blast_Score=130, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014207 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 74557; Mature: 74426

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAIIPHPAPPTHPIFGKLSVDAIPLHEPILVATFIGVAIGGIAVLALLTRYRLWGYLW
CCCCCCCCCCCCCCCCCCCEEECEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEWFTTVDHKRIGIMYMILGLIMFLRGFADAIMMRLQQVMAFGGSEGYLNAHHYDQVFTA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
HGVIMIFFVAMPFITGLMNYIVPLQIGARDVSFPFLNNFSFWMTSAGAALTMISLFVGEY
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCHHHHHCCCHHHHHHHHHHHHH
AQTGWLAYPPLSGIAYSPNVGVDYYIWGLQIAGVGTTLSGINLIVTILKLRAPGMGLMKM
HHCCCEECCCCCCEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHH
PVFTWTSLCSNILIVASFPILTATLALLSLDRYAGTNFFTNDLGGSPMMYVNLIWIWGHP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCC
EVYILILPLFGVFSEVTSTFSGKRLFGYTSMVYATVCITILSYIVWLHHFFTMGSGASVN
CEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
SFFGITTMVISIPTGAKLFNWLFTMYRGRIRYELPMMWTIAFMLTFVVGGMTGVLLAVPP
HHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCHHCEEEEECC
ADFVLHNSLFLIAHFHNVIIGGVLFGLFAAINYWWPKAFGFKLDVFWGKVSFWCWVVGFW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
VAFTPLYILGLMGVTRRMRVFDDPSLQIWFAIAGVGALIIAAGIGAMLVQFAVSIWRRKE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEESGDPWDGRTLEWATSSPPPDYNFAFTPVIHDLDAWYDMKKRGGQRPVGGFRDIHMP
HHHHCCCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
SNTGAGIILSGLCLVLGFALVWHIWWLVGLSFVAVIAGAIIHTFNYKRDFDIPAATVAAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EGARTRQLAAGA
CCCHHHHHCCCC
>Mature Secondary Structure 
SDAIIPHPAPPTHPIFGKLSVDAIPLHEPILVATFIGVAIGGIAVLALLTRYRLWGYLW
CCCCCCCCCCCCCCCCCCEEECEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEWFTTVDHKRIGIMYMILGLIMFLRGFADAIMMRLQQVMAFGGSEGYLNAHHYDQVFTA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
HGVIMIFFVAMPFITGLMNYIVPLQIGARDVSFPFLNNFSFWMTSAGAALTMISLFVGEY
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCHHHHHCCCHHHHHHHHHHHHH
AQTGWLAYPPLSGIAYSPNVGVDYYIWGLQIAGVGTTLSGINLIVTILKLRAPGMGLMKM
HHCCCEECCCCCCEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHH
PVFTWTSLCSNILIVASFPILTATLALLSLDRYAGTNFFTNDLGGSPMMYVNLIWIWGHP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCC
EVYILILPLFGVFSEVTSTFSGKRLFGYTSMVYATVCITILSYIVWLHHFFTMGSGASVN
CEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
SFFGITTMVISIPTGAKLFNWLFTMYRGRIRYELPMMWTIAFMLTFVVGGMTGVLLAVPP
HHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCHHCEEEEECC
ADFVLHNSLFLIAHFHNVIIGGVLFGLFAAINYWWPKAFGFKLDVFWGKVSFWCWVVGFW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
VAFTPLYILGLMGVTRRMRVFDDPSLQIWFAIAGVGALIIAAGIGAMLVQFAVSIWRRKE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEESGDPWDGRTLEWATSSPPPDYNFAFTPVIHDLDAWYDMKKRGGQRPVGGFRDIHMP
HHHHCCCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
SNTGAGIILSGLCLVLGFALVWHIWWLVGLSFVAVIAGAIIHTFNYKRDFDIPAATVAAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EGARTRQLAAGA
CCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]